Research Topics
| G MozsikSummaryCountry: Hungary Publications
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Detail Information
Publications
Leiden mutation (as genetic) and environmental (retinoids) sequences in the acute and chronic inflammatory and premalignant colon disease in human gastrointestinal tractG Mozsik
First Department of Medicine, Medical Faculty, University of Pecs, Pecs 7643, Hungary
J Physiol Paris 95:489-94. 2001..pylori and hepatitis C infections), chronic (ileitis terminalis, ulcerative colitis) GI inflammatory diseases and in colon polyposis without and with malignisation...
[Prevalence of Leiden mutation in various gastrointestinal disorders]Gyula Mozsik
Pecsi Tudomanyegyetem Altalanos Orvostudomanyi Kar, I sz Belgyógyászati Klinika
Orv Hetil 143:447-50. 2002..001). CONCLUSION: The presented results suggest that the Leiden mutation is involved in patients with different inflammatory bowel disease, colon polyposis, as one of the suggested genetic factors...
Mechanisms of action of retinoids in gastrointestinal mucosal protection in animals, human healthy subjects and patientsG Mozsik
First Department of Medicine, University Medical School of Pecs, Hungary
Life Sci 69:3103-12. 2001..intact vagal nerve; b) scavenging properties vs. intact adrenals. 3) The GI mucosal protective effect of retinoids is correlated with biochemical changes in the GI mucosa...
Four response stages of capsaicin-sensitive primary afferent neurons to capsaicin and its analog: gastric acid secretion, gastric mucosal damage and protectionG Mozsik
First Department of Medicine, Medical Faculty, University of Pecs, Hungary
J Gastroenterol Hepatol 16:1093-7. 2001..The final effects of capsaicin depend on the dosage and timing. The different effects are excitation, a sensory-blocking effect, long-term selective neurotoxic impairment and irreversible cell destruction...
The key-role of vagal nerve and adrenals in the cytoprotection and general gastric mucosal integrityG Mozsik
First Department of Medicine, Faculty of Medicine, University of Pecs, H 7643 Pecs, Ifjusag u 13, Hungary
J Physiol Paris 95:229-37. 2001..Similarly to this, the beta-carotene induced gastric cytoprotection disappeared in adrenalectomized rats too...
Prevalence of the factor V Leiden mutation in human inflammatory bowel disease with different activityZ Nagy
First Department of Medicine, University of Pecs, Medical Faculty, PO Box 99, H 7643 Pecs, Ifjusag u 13, Hungary
J Physiol Paris 95:483-7. 2001..AIMS of this study were: (1) to classify the IBD patients according the disease activity; and (2) to determine the presence of factor V Leiden mutation in IBD patients...
Atropine-induced gastrointestinal cytoprotection dependences to the intact of vagal nerve against indomethacin-induced gastrointestinal mucosal and microvascular damage in ratsO Karádi
First Department of Medicine, Medical Faculty of University of Pécs, H 7643 Pecs, PO Box 99, Hungary
J Physiol Paris 95:29-33. 2001....
Expanded parietal cell pool in transgenic mice unable to synthesize histamineB Hunyady
First Dept of Medicine, Medical Faculty, University of Pecs, Pecs, Hungary
Scand J Gastroenterol 38:133-40. 2003..The histidine decarboxylase enzyme (HDC) is responsible for the synthesis of histamine in mammals. Histidine decarboxylase-deficient (HDC-/-) mice have recently been developed by targeted mutation of the HDC gene...
Gastrointestinal cytoprotection: from basic science to clinical perspectivesG Mozsik
First Department of Medicine, Medical and Health Centre, University of Pecs, Pecs, Hungary
Inflammopharmacology 15:49-60. 2007..This paper gives a short overview on the different approaches for the exploring gastrointestinal cytoprotection...
Failure of capsaicin-containing red pepper sauce suspension to induce esophageal motility response in patients with Barrett's esophagusA Kiraly
First Department of Medicine, University of Pecs, Hungary, H 7643 Pecs, Ifjusag u 13, Hungary
J Physiol Paris 95:197-200. 2001..0) suspension on the phasic activity of the human esophagus of healthy volunteers and patients with Barrett's esophagus...
Capsaicin research as a new tool to approach of the human gastrointestinal physiology, pathology and pharmacologyG Mozsik
First Department of Medicine, Medical and Health Centre, University of Pecs, H 7643, Pecs, Hungary
Inflammopharmacology 15:232-45. 2007..Capsaicin has been found to act on the capsaicin sensitive afferent nerves in animal experiments...
One year follow-up of patients after successful helicobacter pylori eradication therapyA Vincze
First Department of Medicine, Faculty of Medicine, University of Pecs, Pecs, Hungary
J Physiol Paris 95:457-60. 2001..The aim of this study was to investigate the Helicobacter pylori (Hp) status of patients who underwent successful eradication therapy 1 year prior to the study and to evaluate their current symptoms...
Plasma carnitine ester profiles in Crohn's disease and ulcerative colitis patients with different IGR2230a_1 genotypesG Talian
Department of Medical Genetics and Child Development, University of Pecs, H 7624 Pecs, Hungary
Int J Immunogenet 36:329-35. 2009..Our data suggest that this polymorphism alone is not associated with CD and UC in the Hungarian population, and has no effect on the carnitine metabolism...
Susceptibility of dopamine D5 receptor targeted mice to cysteamineB Hunyady
First Department of Internal Medicine, Medical Faculty, University of Pecs, Hungary
J Physiol Paris 95:147-51. 2001..Out of five different subtypes, mRNA of D5 (=D1b) dopamine receptor is very abundant in the gastric epithelium. D1 receptor selective dopamine agonists have been shown to protect against experimental gastro-duodenal lesions...
Otilonium bromide enhances sensory thresholds of volume and pressure in patients with irritable bowel syndromeJ Czimmer
First Department of Medicine, University of Pecs, H 7643 Pecs, Ifjusag u 13, Hungary
J Physiol Paris 95:153-6. 2001..Aims: to determine whether otilonium bromide can influence sensory thresholds of patients suffering from irritable bowel syndrome...
Search for factor V Arg306 Cambridge and Hong Kong mutations in mixed Hungarian population samplesK Komlosi
Department of Medical Genetics and Child Development, Faculty of Medicine, University of Pecs, Pecs, Hungary
Acta Haematol 110:220-2. 2003
Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in ratsB Bódis
First Department of Medicine, Medical Faculty, University of Pecs, Hungary
J Physiol Paris 95:271-5. 2001..THE AIM OF OUR STUDY was to evaluate the changes in the tissue level of aquaporins (AQP1 and AQP4) after ethanol and capsaicin treatment in rat stomach...
