Tamas F Freund

Summary

Affiliation: Institute of Experimental Medicine
Country: Hungary

Publications

  1. ncbi request reprint Role of endogenous cannabinoids in synaptic signaling
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 8, Szigony u 43, H 1083 Hungary
    Physiol Rev 83:1017-66. 2003
  2. ncbi request reprint Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro
    Norbert Hajos
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H 1450, Hungary
    J Neurosci 24:9127-37. 2004
  3. ncbi request reprint Distinct properties of two major excitatory inputs to hippocampal pyramidal cells: a computational study
    Szabolcs Káli
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, PO Box 67, Budapest H 1450, Hungary
    Eur J Neurosci 22:2027-48. 2005
  4. pmc CB1 receptor-dependent and -independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212-2
    Beáta Németh
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, Budapest H 1450, Hungary
    Neuropharmacology 54:51-7. 2008
  5. ncbi request reprint Perisomatic inhibition
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Neuron 56:33-42. 2007
  6. ncbi request reprint Changes in the views of neuronal connectivity and communication after Cajal: examples from the hippocampus
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, H 1083 Budapest, Hungary
    Prog Brain Res 136:203-13. 2002
  7. ncbi request reprint Interneuron Diversity series: Rhythm and mood in perisomatic inhibition
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, PO Box 67, H 1450, Hungary
    Trends Neurosci 26:489-95. 2003
  8. pmc Nitric oxide signaling modulates synaptic transmission during early postnatal development
    Csaba Cserép
    Laboratory of Cerebral Cortex Research, Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    Cereb Cortex 21:2065-74. 2011
  9. pmc Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons
    Zoltan Peterfi
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 32:14448-63. 2012
  10. doi request reprint Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus
    Anikó Ludányi
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 28:2976-90. 2008

Collaborators

Detail Information

Publications59

  1. ncbi request reprint Role of endogenous cannabinoids in synaptic signaling
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 8, Szigony u 43, H 1083 Hungary
    Physiol Rev 83:1017-66. 2003
    ..Finally, the possible functions of endocannabinoids as retrograde synaptic signal molecules are discussed in relation to synaptic plasticity and network activity patterns...
  2. ncbi request reprint Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro
    Norbert Hajos
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H 1450, Hungary
    J Neurosci 24:9127-37. 2004
    ....
  3. ncbi request reprint Distinct properties of two major excitatory inputs to hippocampal pyramidal cells: a computational study
    Szabolcs Káli
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, PO Box 67, Budapest H 1450, Hungary
    Eur J Neurosci 22:2027-48. 2005
    ..In this case, the efficacy of the PP was enhanced by the dendritic generation and limited spread of action potentials. Strong PP activation could also evoke dendritic Ca++ spikes, which often triggered a somatic burst...
  4. pmc CB1 receptor-dependent and -independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212-2
    Beáta Németh
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, Budapest H 1450, Hungary
    Neuropharmacology 54:51-7. 2008
    ....
  5. ncbi request reprint Perisomatic inhibition
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Neuron 56:33-42. 2007
    ..The well-balanced cooperation of the two inhibitory systems is required for the normal network operations underlying the cognitive functions of the cerebral cortex...
  6. ncbi request reprint Changes in the views of neuronal connectivity and communication after Cajal: examples from the hippocampus
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, H 1083 Budapest, Hungary
    Prog Brain Res 136:203-13. 2002
    ..Cajal would be delighted to see the revitalization of functional neuroanatomy, particularly of molecular anatomy, among the modern disciplines in the neurosciences today...
  7. ncbi request reprint Interneuron Diversity series: Rhythm and mood in perisomatic inhibition
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, PO Box 67, H 1450, Hungary
    Trends Neurosci 26:489-95. 2003
    ..Impairment of this inhibitory mechanism is likely to result in mood disorders such as anxiety...
  8. pmc Nitric oxide signaling modulates synaptic transmission during early postnatal development
    Csaba Cserép
    Laboratory of Cerebral Cortex Research, Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    Cereb Cortex 21:2065-74. 2011
    ....
  9. pmc Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons
    Zoltan Peterfi
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 32:14448-63. 2012
    ..The shifted induction threshold implies that endocannabinoid-LTD contributes to cortical information processing during distinct network activity patterns in a cell type-specific manner...
  10. doi request reprint Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus
    Anikó Ludányi
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 28:2976-90. 2008
    ....
  11. ncbi request reprint Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes
    Resat Cinar
    Institute of Biochemistry, Biological Research Center, Hungarian Academy of Sciences, Szeged, Hungary
    Neurochem Int 52:1402-9. 2008
    ....
  12. pmc NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling
    Eszter Szabadits
    Laboratory of Cerebral Cortex Research, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083, Budapest, Hungary
    J Neurosci 31:5893-904. 2011
    ..These data indicate that NMDARs can modulate hippocampal GABAergic inhibition via NO-cGMP signaling in an activity-dependent manner and that this effect is subregion specific in the mouse hippocampus...
  13. ncbi request reprint Post-natal development of type 1 cannabinoid receptor immunoreactivity in the rat hippocampus
    Yury M Morozov
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Szigony u 43, H 1083 Hungary
    Eur J Neurosci 18:1213-22. 2003
    ..This suggests that retrograde synaptic signalling by endocannabinoids is required for the normal operation of GABAergic neurotransmission even before it becomes hyperpolarizing...
  14. ncbi request reprint Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition
    Norbert Hajos
    Department of Functional Neuroanatomy, Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, H 1450, Budapest, Hungary
    Chem Phys Lipids 121:73-82. 2002
    ..Thus, at least two different cannabinoid sensitive presynaptic receptors regulate network activity in the hippocampus, CB1 via the GABAergic interneurons, and a new receptor via a direct action on pyramidal cell axon terminals...
  15. pmc Laminar analysis of slow wave activity in humans
    Richard Csercsa
    Institute for Psychology, Hungarian Academy of Sciences, Budapest, Hungary
    Brain 133:2814-29. 2010
    ..Our results emphasize the major involvement of supragranular layers in the genesis of slow wave activity...
  16. ncbi request reprint Fast synaptic subcortical control of hippocampal circuits
    Viktor Varga
    Institute of Experimental Medicine, Budapest 1083, Hungary
    Science 326:449-53. 2009
    ..This form of subcortical network regulation should be incorporated into current concepts of normal and pathological cortical function...
  17. pmc Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro
    Norbert Hajos
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    J Neurosci 33:11677-91. 2013
    ..Thus, in addition to gamma oscillation, these GABAergic cells play a central role in SWR generation. ..
  18. ncbi request reprint The effects of cannabinoids on contextual conditioned fear in CB1 knockout and CD1 mice
    Eva Mikics
    Institute of Experimental Medicine, Budapest, Hungary
    Behav Pharmacol 17:223-30. 2006
    ..Data are interpreted in terms of the potential involvement of cannabinoids in trauma-induced behavioral changes...
  19. pmc Loss and reorganization of calretinin-containing interneurons in the epileptic human hippocampus
    Kinga Tóth
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, Budapest, Hungary
    Brain 133:2763-77. 2010
    ..We hypothesize that reorganization of the interneuron-selective cells may be implicated in the occurrence of seizures in non-sclerotic patients, where the majority of principal and non-principal cells are preserved...
  20. pmc Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area
    Ferenc Matyas
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, H 1083 Budapest, Hungary
    Neuropharmacology 54:95-107. 2008
    ..These findings indicate that retrograde synaptic signaling mediated by 2-AG via CB(1) may influence the drug-reward circuitry at multiple types of synapses in the VTA...
  21. pmc Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics
    Rita Zemankovics
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    J Physiol 588:2109-32. 2010
    ....
  22. ncbi request reprint Involvement of nitric oxide in depolarization-induced suppression of inhibition in hippocampal pyramidal cells during activation of cholinergic receptors
    Judit K Makara
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 27:10211-22. 2007
    ....
  23. pmc Complex propagation patterns characterize human cortical activity during slow-wave sleep
    Balázs Hangya
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    J Neurosci 31:8770-9. 2011
    ..At larger spatial scales, the orderly SWA propagation dominates; at the finer scale of the ECoG recordings, non-REM sleep is characterized by complex SWA propagation patterns...
  24. ncbi request reprint GABAergic neurons of the medial septum lead the hippocampal network during theta activity
    Balázs Hangya
    Laboratory of Cerebral Cortex Research, Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 29:8094-102. 2009
    ..Thus, a pacemaker neuron population of the MS leads hippocampal activity, presumably via the synchronization of hippocampal interneurons...
  25. pmc Distinct synaptic properties of perisomatic inhibitory cell types and their different modulation by cholinergic receptor activation in the CA3 region of the mouse hippocampus
    Gergely G Szabó
    Laboratory of Network Neurophysiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    Eur J Neurosci 31:2234-46. 2010
    ..These findings suggest that not only are the basic synaptic properties of perisomatic inhibitory cells distinct, but acetylcholine can differentially control the impact of perisomatic inhibition from different sources...
  26. pmc Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus
    Attila I Gulyás
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 30:15134-45. 2010
    ..These results collectively suggest that the rhythmic perisomatic inhibition, generating oscillatory fluctuation in local field potentials after carbachol treatment of hippocampal slices, is the result of periodic GABA release from FSBCs...
  27. ncbi request reprint Excitement reduces inhibition via endocannabinoids
    Tamas F Freund
    Department of Functional Neuroanatomy, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1450, Budapest, Hungary
    Neuron 38:362-5. 2003
    ..In this issue of Neuron, Chevaleyre and Castillo provide evidence for another form of endocannabinoid-mediated depression of hippocampal inhibition, which is activity dependent and long lasting...
  28. ncbi request reprint Impaired and repaired inhibitory circuits in the epileptic human hippocampus
    Zsófia Maglóczky
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, POB 67, H 1450, Hungary
    Trends Neurosci 28:334-40. 2005
    ..The highly heterogeneous, but specific, alterations of GABAergic interneuron circuits have important implications for the pharmacotherapy of epilepsy...
  29. ncbi request reprint Immunocytochemically defined interneuron populations in the hippocampus of mouse strains used in transgenic technology
    Ferenc Matyas
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Hippocampus 14:460-81. 2004
    ..We can conclude that the morphofunctional classification of interneurons established in the rat is largely valid for mouse strains used in transgenic procedures...
  30. ncbi request reprint Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus
    Judit K Makara
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 8 Szigony u 43, Budapest, H 1083 Hungary
    Nat Neurosci 8:1139-41. 2005
    ..These results establish a role for 2-AG in synaptic plasticity and point to monoacylglycerol lipase as a possible drug target...
  31. pmc Molecular composition of the endocannabinoid system at glutamatergic synapses
    Istvan Katona
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 26:5628-37. 2006
    ....
  32. ncbi request reprint Hippocampal GABAergic synapses possess the molecular machinery for retrograde nitric oxide signaling
    Eszter Szabadits
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1450 Budapest, Hungary
    J Neurosci 27:8101-11. 2007
    ....
  33. pmc Maintaining network activity in submerged hippocampal slices: importance of oxygen supply
    Norbert Hajos
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, 1083 Budapest, Hungary
    Eur J Neurosci 29:319-27. 2009
    ..These improvements to the recording conditions enable detailed studies of neurons under more realistic conditions of network activity, which are essential for a better understanding of neuronal network operation...
  34. ncbi request reprint Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types
    Agnes L Bodor
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1450 Budapest, Hungary
    J Neurosci 25:6845-56. 2005
    ....
  35. doi request reprint Physiological sharp wave-ripples and interictal events in vitro: what's the difference?
    Mária R Karlócai
    1 Laboratory of Cerebral Cortex, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Brain 137:463-85. 2014
    ..Thus, the collapse of pyramidal cell perisomatic inhibition appears to be a crucial factor in the emergence of epileptiform events. ..
  36. doi request reprint The effects of an Echinacea preparation on synaptic transmission and the firing properties of CA1 pyramidal cells in the hippocampus
    Norbert Hajos
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Phytother Res 26:354-62. 2012
    ..In summary, the Echinacea extract can significantly regulate excitatory, but not inhibitory, synaptic transmission in the hippocampus, and this action might be involved in its anxiolytic effects observed in behaviour tests...
  37. pmc Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans
    Zsófia Maglóczky
    Hungarian Academy of Sciences, Institute of Experimental Medicine, Budapest, Hungary
    Epilepsia 51:115-20. 2010
    ..Pharmacotherapy aimed at the modulation of endocannabinoid-mediated retrograde synaptic signaling should take into account the opposite change in CB1-receptor expression observed on glutamatergic versus GABAergic axon terminals...
  38. ncbi request reprint GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons
    Gábor Nyiri
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Szigony u 43, Hungary
    Eur J Neurosci 21:3034-42. 2005
    ..The results also suggest that cholinergic transmission in the hippocampus is fine-tuned by endocannabinoid signalling...
  39. doi request reprint Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals
    Rita Nyilas
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1083 Budapest, Hungary
    J Neurosci 28:1058-63. 2008
    ....
  40. pmc Redistribution of CB1 cannabinoid receptors in the acute and chronic phases of pilocarpine-induced epilepsy
    Mária R Karlócai
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    PLoS ONE 6:e27196. 2011
    ....
  41. pmc NMDA receptors in GABAergic synapses during postnatal development
    Csaba Cserép
    Laboratory of Cerebral Cortex Research, Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    PLoS ONE 7:e37753. 2012
    ..This additional level of cooperation that operates within the depolarizing GABAergic synapse, may also allow its own modification triggered by Ca(2+)-influx through the NMDA receptors...
  42. ncbi request reprint Convergence of excitatory and inhibitory inputs onto CCK-containing basket cells in the CA1 area of the rat hippocampus
    Ferenc Matyas
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, PO Box 67, H 1450, Hungary
    Eur J Neurosci 19:1243-56. 2004
    ..Additional differences in their anatomical and physiological properties predict that CCK basket cells are under a more diverse, elaborate control than PV basket cells, and thus the function of the two populations must be different...
  43. ncbi request reprint Endocannabinoid transport tightly controls 2-arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404
    Norbert Hajos
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony u 43, H 1083 Budapest, Hungary
    Eur J Neurosci 19:2991-6. 2004
    ....
  44. pmc DAG-sensitive and Ca(2+) permeable TRPC6 channels are expressed in dentate granule cells and interneurons in the hippocampal formation
    Gergo A Nagy
    Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1450 Budapest, Hungary
    Hippocampus 23:221-32. 2013
    ..2012 Wiley Periodicals, Inc...
  45. doi request reprint Multiple functions of endocannabinoid signaling in the brain
    Istvan Katona
    Institute of Experimental Medicine, Hungarian Academy of Sciences, 1051 Budapest, Hungary
    Annu Rev Neurosci 35:529-58. 2012
    ..Finally, we discuss how cell type- and synapse-specific refinement of endocannabinoid signaling may explain the characteristic behavioral effects of cannabinoids...
  46. doi request reprint Types and synaptic connections of hippocampal inhibitory neurons reciprocally connected with the medial septum
    Virág T Takács
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, PO Box 67, H 1450 Hungary
    Eur J Neurosci 28:148-64. 2008
    ..oriens and radiatum. The synaptic organization suggests that by sampling the activity of large populations of principal cells HS cells can reliably broadcast hippocampal activity level to the medial septum...
  47. pmc Neuroligin 2 is expressed in synapses established by cholinergic cells in the mouse brain
    Virág T Takács
    Laboratory of Cerebral Cortex Research, Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    PLoS ONE 8:e72450. 2013
    ....
  48. doi request reprint Extrinsic and local glutamatergic inputs of the rat hippocampal CA1 area differentially innervate pyramidal cells and interneurons
    Virág T Takács
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Hippocampus 22:1379-91. 2012
    ..lacunosum-moleculare. The results highlight differences in the postsynaptic target selection of the feed-forward versus recurrent glutamatergic inputs to the CA1 and CA3 areas...
  49. ncbi request reprint Molecular architecture of the cannabinoid signaling system in the core of the nucleus accumbens
    Ferenc Matyas
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest
    Ideggyogy Sz 60:187-91. 2007
    ....
  50. doi request reprint Glutamatergic input from specific sources influences the nucleus accumbens-ventral pallidum information flow
    Edit Papp
    Laboratory of Cerebral Cortex Research, Institute of Experimental Medicine, Hungarian Academy of Sciences, H 1450 Budapest, P O BOX 67, Budapest, Hungary
    Brain Struct Funct 217:37-48. 2012
    ..e. mPFC, vHC, BLA, TH) to the NAc might thus convey different types of reward-related information during goal-directed behaviour, and thereby contribute to the complex regulation of nucleus accumbens functions...
  51. ncbi request reprint The spatial and temporal pattern of fatty acid amide hydrolase expression in rat hippocampus during postnatal development
    Yury M Morozov
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, H 1083, Budapest, Hungary
    Eur J Neurosci 20:459-66. 2004
    ..Instead, FAAH may subserve general roles as the inactivating enzyme for many fatty acid amides, in addition to anandamide...
  52. doi request reprint Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
    Istvan Katona
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, H 1083 Budapest, Hungary
    Nat Med 14:923-30. 2008
    ....
  53. pmc Control of excitatory synaptic transmission by capsaicin is unaltered in TRPV1 vanilloid receptor knockout mice
    Felix Benninger
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H 1450, Hungary
    Neurochem Int 52:89-94. 2008
    ..These data strongly argue against the hypothesis that capsaicin modulates excitatory synaptic transmission by activating TRPV1Rs, at least in the hippocampal network...
  54. pmc The presence of pacemaker HCN channels identifies theta rhythmic GABAergic neurons in the medial septum
    Viktor Varga
    Department of Cell and Network Neurobiology, Institute of Experimental Medicine of the Hungarian Academy of Sciences Szigony u 43 Budapest, 1083 Hungary
    J Physiol 586:3893-915. 2008
    ..In most MS theta cells rhythm genesis is apparently determined by interactions at the level of the network rather than by the pacemaking property of HCN channels alone...
  55. ncbi request reprint Different input and output properties characterize parvalbumin-positive basket and Axo-axonic cells in the hippocampal CA3 subfield
    Orsolya I Papp
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Hippocampus 23:903-18. 2013
    ..Thus, CA3 pyramidal cells more profoundly innervate BCs than AACs, which could explain, at least in part, their distinct spiking behavior under different hippocampal network activities. © 2013 Wiley Periodicals, Inc. ..
  56. ncbi request reprint Populations of hippocampal inhibitory neurons express different levels of cytochrome c
    Attila I Gulyás
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Eur J Neurosci 23:2581-94. 2006
    ..Thus, similar to the parvalbumin-containing basket and axo-axonic cells, the hippocampo-septal neurons potentially have a high average activity level...
  57. doi request reprint The anxiolytic potential and psychotropic side effects of an echinacea preparation in laboratory animals and healthy volunteers
    Jozsef Haller
    Institute of Experimental Medicine, Budapest, Hungary
    Phytother Res 27:54-61. 2013
    ..The lower dose (1 tablet per day) did not affect anxiety significantly...
  58. ncbi request reprint Cell type-specific differences in chloride-regulatory mechanisms and GABA(A) receptor-mediated inhibition in rat substantia nigra
    Alexandra Gulacsi
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, H 1083 Hungary
    J Neurosci 23:8237-46. 2003
    ..The relatively low efficacy of GABAA-mediated inhibition in nigral dopaminergic neurons compared with nigral GABAergic neurons may be related to their lack of KCC2...
  59. ncbi request reprint Properties of in vivo interictal spike generation in the human subiculum
    Dániel Fabó
    Institute for Psychology, Hungarian Academy of Sciences, 1068 Budapest, Szondi u 83 85, Hungary
    Brain 131:485-99. 2008
    ..Limited data suggest that subiculum might even play a pacemaker role in the generation of paroxysmal discharges...