Andrew E Czeizel

Summary

Affiliation: Foundation for the Community Control of Hereditary Diseases
Country: Hungary

Publications

  1. ncbi request reprint Association between severe nausea and vomiting in pregnancy and lower rate of preterm births
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Paediatr Perinat Epidemiol 18:253-9. 2004
  2. ncbi request reprint Population-based case-control study of mebendazole in pregnant women for birth outcomes
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 45:85-8. 2005
  3. ncbi request reprint Association between bronchial asthma in pregnancy and shorter gestational age in a population-based study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    J Matern Fetal Neonatal Med 18:107-12. 2005
  4. ncbi request reprint Maternal panic disorder and congenital abnormalities: a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 76:253-61. 2006
  5. doi request reprint Maternal demographic and socioeconomic characteristics of live-born infants with isolated ocular congenital abnormalities
    Erzsebet H Puho
    National Center for Healthcare Audit and Improvement, Budapest, Hungary
    Ophthalmic Epidemiol 15:257-63. 2008
  6. ncbi request reprint A population-based case-control study of oral griseofulvin treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, National Center for Epidemiology, Budapest, Hungary
    Acta Obstet Gynecol Scand 83:827-31. 2004
  7. ncbi request reprint Effect of vaginal metronidazole + miconazole treatment during pregnancy for gestational age and birth weight in a population-based study
    Zoltán Kazy
    Foundation for the Community Control of Hereditary Diseases, Trkvsz lejt 32, Budapest, 1026, Hungary
    Arch Gynecol Obstet 272:294-7. 2005
  8. ncbi request reprint Acute respiratory infections during pregnancy and congenital abnormalities: a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 46:86-96. 2006
  9. doi request reprint Delineation of a multiple congenital abnormality syndrome in the offspring of pregnant women affected with high fever-related disorders: a population-based study
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 48:158-66. 2008
  10. doi request reprint Birth outcomes of cases with isolated atrial septal defect type II--a population-based case-control study
    Attila Vereczkey
    Versys Clinics, Human Reproduction Institute, Budapest, Hungary
    Acta Obstet Gynecol Scand 92:824-9. 2013

Detail Information

Publications93

  1. ncbi request reprint Association between severe nausea and vomiting in pregnancy and lower rate of preterm births
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Paediatr Perinat Epidemiol 18:253-9. 2004
    ..4% vs. 9.5%). This finding may be connected with the favourable hormonal milieu (larger placenta, higher level of chorionic gonadotrophin and oestrogens) of pregnant women with nausea and vomiting...
  2. ncbi request reprint Population-based case-control study of mebendazole in pregnant women for birth outcomes
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 45:85-8. 2005
    ..Thus, treatment with mebendazole during pregnancy did not indicate a teratogenic and fetotoxic risk to the embryo or fetus, though the numbers of treated cases and controls in this study were limited...
  3. ncbi request reprint Association between bronchial asthma in pregnancy and shorter gestational age in a population-based study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    J Matern Fetal Neonatal Med 18:107-12. 2005
    ..To study the association between bronchial asthma during pregnancy and gestational age/birth weight, and also preterm birth and low birth weight...
  4. ncbi request reprint Maternal panic disorder and congenital abnormalities: a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 76:253-61. 2006
    ..Maternal panic disorder in pregnancy is the most common manifestation of anxiety disorders in Hungary. The association between panic disorder during pregnancy and structural birth defects, i.e., congenital abnormalities, was studied...
  5. doi request reprint Maternal demographic and socioeconomic characteristics of live-born infants with isolated ocular congenital abnormalities
    Erzsebet H Puho
    National Center for Healthcare Audit and Improvement, Budapest, Hungary
    Ophthalmic Epidemiol 15:257-63. 2008
    ..To evaluate maternal age and birth order, in addition socioeconomic status and finally occupational background of mothers who delivered babies with different isolated ocular congenital abnormalities...
  6. ncbi request reprint A population-based case-control study of oral griseofulvin treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, National Center for Epidemiology, Budapest, Hungary
    Acta Obstet Gynecol Scand 83:827-31. 2004
    ..To study the teratogenicity of oral griseofulvin during pregnancy...
  7. ncbi request reprint Effect of vaginal metronidazole + miconazole treatment during pregnancy for gestational age and birth weight in a population-based study
    Zoltán Kazy
    Foundation for the Community Control of Hereditary Diseases, Trkvsz lejt 32, Budapest, 1026, Hungary
    Arch Gynecol Obstet 272:294-7. 2005
    ..5% after this treatment compared with the 9.2% of preterm birth in the untreated group. Thus the combination of M+M was not able to reduce the preterm birth associated with vulvovaginal infections/disorders...
  8. ncbi request reprint Acute respiratory infections during pregnancy and congenital abnormalities: a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 46:86-96. 2006
    ..However, periconceptional multivitamin/folic acid supplementation during the early pregnancy was able to reduce the acute respiratory infection related risk for congenital abnormalities...
  9. doi request reprint Delineation of a multiple congenital abnormality syndrome in the offspring of pregnant women affected with high fever-related disorders: a population-based study
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 48:158-66. 2008
    ..0%) among 181 MCA babies born to mothers with high fever-related diseases. In the total dataset of 1349 MCA, 2.8% of cases can be associated with high fever...
  10. doi request reprint Birth outcomes of cases with isolated atrial septal defect type II--a population-based case-control study
    Attila Vereczkey
    Versys Clinics, Human Reproduction Institute, Budapest, Hungary
    Acta Obstet Gynecol Scand 92:824-9. 2013
    ..e. only a fossa ovalis defect) after surgical correction or lethal outcome in the light of maternal sociodemographic data...
  11. ncbi request reprint A population-based case-control study on the effect of bronchial asthma during pregnancy for congenital abnormalities of the offspring
    Lilla Tamási
    Semmelweis University, School of Medicine, Department of Respiratory Medicine, Budapest, Hungary
    J Asthma 43:81-6. 2006
    ..The main limitation of the analysis was that at the time of data collection only a small proportion of pregnant mothers were using anti-asthma medications recommended by the actual guidelines...
  12. ncbi request reprint Pregnancy complications and delivery outcomes of pregnant women with influenza
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    J Matern Fetal Neonatal Med 19:135-40. 2006
    ..The aim of this study was to ascertain the relationship between influenza during pregnancy and pregnancy complications, and in addition, delivery outcomes particularly preterm birth and low birth weight in newborns...
  13. ncbi request reprint Teratogenic potential of vaginal metronidazole treatment during pregnancy
    Zoltán Kazy
    Foundation for the Community Control of Hereditary Diseases, Torokvesz Lejto 32, 1026 Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 123:174-8. 2005
    ..To study the human teratogenic potential of vaginal metronidazole treatment during pregnancy...
  14. doi request reprint Senna treatment in pregnant women and congenital abnormalities in their offspring--a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Reprod Toxicol 28:100-4. 2009
    ..In conclusion, senna treatment did not associate with a higher risk of CAs in the offspring of pregnant women with constipation...
  15. doi request reprint Teratogenic potential of pholedrine: a sympathomimetic vasoconstrictive drug - a population-based case-control study
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis, University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 50:122-8. 2010
    ..The knowledge of the teratogenic potential of pholedrine may contribute to the evaluation of other sympathomimetic drugs...
  16. ncbi request reprint The use of data set of the Hungarian case-control surveillance of congenital abnormalities for evaluation of birth outcomes beyond birth defects
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Cent Eur J Public Health 15:147-53. 2007
    ....
  17. ncbi request reprint Maternal acute respiratory infectious diseases during pregnancy and birth outcomes
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Epidemiol 23:29-35. 2008
    ..5%, adjusted OR with 95% CI: 0.5, 0.4-0.7). In conclusion, there was an obvious correlation between severity of ARID in pregnant women and rate of preterm births...
  18. ncbi request reprint Maternal influenza during pregnancy and risk of congenital abnormalities in offspring
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 73:989-96. 2005
    ....
  19. ncbi request reprint Pregnancy complications and delivery outcomes of pregnant women with common cold
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Cent Eur J Public Health 14:10-4. 2006
    ..To study the association between common cold during pregnancy and pregnancy complications and delivery outcomes: gestational age/birth weight, in addition preterm birth and low birthweight...
  20. ncbi request reprint Population-based case-control study of oxoline acid use during pregnancy for birth outcomes
    Istvan Dudás
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Congenit Anom (Kyoto) 46:39-42. 2006
    ..Our data did not indicate teratogenic and fetotoxic effect of oxoline acid, however, the number of cases and controls was limited...
  21. ncbi request reprint Maternal severe migraine and risk of congenital limb deficiencies
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 76:592-601. 2006
    ..Therefore, we examined the risk of congenital abnormalities in infants born to women who had migraines and other headaches during pregnancy...
  22. ncbi request reprint The possible association between the combination of vaginal metronidazole and miconazole treatment and poly-syndactyly Population-based case-control teratologic study
    Zoltán Kazy
    Foundation for the Community Control of Hereditary Diseases, Torokvesz Lejto 32, H 1026 Budapest, Hungary
    Reprod Toxicol 20:89-94. 2005
    ....
  23. ncbi request reprint Population-based case-control study of oral ketoconazole treatment for birth outcomes
    Zoltán Kazy
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Congenit Anom (Kyoto) 45:5-8. 2005
    ..Our study failed to demonstrate a higher rate of congenital abnormalities in infants with mothers who had received oral ketoconazole treatment during pregnancy...
  24. doi request reprint No association between severe constipation with related drug treatment in pregnant women and congenital abnormalities in their offspring: A population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Congenit Anom (Kyoto) 50:15-20. 2010
    ..A higher rate of CA was not found in the offspring of pregnant women with severe constipation and related senna treatment...
  25. doi request reprint Rate of preterm births in pregnant women with common lower genital tract infection: a population-based study based on the clinical practice
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    J Matern Fetal Neonatal Med 22:410-8. 2009
    ..To estimate the rate of preterm births in pregnant women with lower genital tract infection, i.e. vulvovaginitis-bacterial vaginosis and to check their prevention by drug treatments in the usual clinical practice...
  26. ncbi request reprint A population-based case-control study of isolated primary congenital glaucoma
    Gábor Vogt
    Hospital and Central Outpatients Clinics of the Hungarian State Railways, Budapest, Hungary
    Am J Med Genet A 140:1148-55. 2006
    ..We conclude that the higher incidence of IPCG in the Hungarian Gypsy population is associated with their inbreeding and the possible founder effect of a gene mutation...
  27. ncbi request reprint Pregnancy complications and birth outcomes of pregnant women with urinary tract infections and related drug treatments
    Ferenc Banhidy
    Second Department of Obstetrics and Gynaecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Scand J Infect Dis 39:390-7. 2007
    ..In conclusion, maternal urinary tract infections during pregnancy increase pre-eclampsia and polyhydramnios, and in addition the rate of preterm birth; however, the latter is preventable by appropriate drug treatments...
  28. doi request reprint Possible association between acute pelvic inflammatory disease in pregnant women and congenital abnormalities in their offspring: a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 82:563-70. 2008
    ..The possible association between acute pelvic inflammatory diseases (APID) of pregnant women and structural birth defects, that is, congenital abnormalities (CA) in their offspring, has not been studied...
  29. doi request reprint Iron deficiency anemia: pregnancy outcomes with or without iron supplementation
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Nutrition 27:65-72. 2011
    ..To estimate the efficacy of iron supplementation in anemic pregnant women on the basis of occurrence of pregnancy complications and birth outcomes...
  30. ncbi request reprint A population-based case-control teratologic study of oral dipyrone treatment during pregnancy
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Drug Saf 30:59-70. 2007
    ..To study the possible human teratogenic effect of oral dipyrone, an antipyretic and analgesic drug treatment during pregnancy...
  31. ncbi request reprint Maternal diseases and isolated orofacial clefts in Hungary
    Julia Metneki
    National Center for Epidemiology, Department of Human Genetics and Teratology, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 73:617-23. 2005
    ....
  32. ncbi request reprint Possible association between maternal recurrent orofacial herpes in pregnancy and a lower rate of preterm birth
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    J Matern Fetal Neonatal Med 19:537-42. 2006
    ..To study the possible association between orofacial herpes during pregnancy and pregnancy complications including preterm birth and low birth weight, since the results of previous studies are inconsistent...
  33. ncbi request reprint Pregnancy complications and delivery outcomes in pregnant women with severe migraine
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 134:157-63. 2007
    ..The objective was to study the possible association among maternal migraine during pregnancy, pregnancy complications, and the delivery outcomes: sex ratio, gestational age/birth weight and preterm birth/low birth weight...
  34. ncbi request reprint Drug treatment during pregnancy and isolated orofacial clefts in hungary
    Erzsebet H Puho
    National Center for Healthcare Audit and Improvement, Department of Human Genetics and Teratology and the Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Cleft Palate Craniofac J 44:194-202. 2007
    ..To evaluate the possible association between all kinds of drug treatments during pregnancy and isolated cleft lip with or without cleft palate (CL/P) and posterior cleft palate (PCP) in the offspring...
  35. ncbi request reprint Population-based case-control study of allergic rhinitis during pregnancy for birth outcomes
    Akos Somoskovi
    Department of Respiratory Medicine, School of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 131:21-7. 2007
    ..The present study aimed to estimate the effect of maternal allergic rhinitis on birth outcomes, in particular congenital abnormalities, preterm birth and low birthweight newborns...
  36. ncbi request reprint A population-based case-control teratological study of vaginal econazole treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 111:135-40. 2003
    ..To study human risk and benefit of vaginal econazole treatment during pregnancy...
  37. doi request reprint Possible association between symptomatic cholelithiasis-complicated cholecystitis in pregnant women and congenital abnormalities in their offspring--a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 146:152-5. 2009
    ..To estimate the risk of congenital abnormalities in the offspring of pregnant women with symptomatic cholelithiasis and complicated cholecystitis...
  38. ncbi request reprint Maternal diseases and risk of isolated ear abnormalities in their children
    László Paput
    Department of Oto Rhino Laryngologic and Head Neck Surgical Department, National Center for Healthcare Audit and Improvement, Budapest, Hungary
    Cent Eur J Public Health 19:170-6. 2011
    ..In conclusion high fever related influenza-common cold with secondary complications may play a role in the origin of IECA, but is preventable with the early and effective antifever treatment of these pregnant women...
  39. ncbi request reprint A possible association between maternal glomerulonephritis and congenital intestinal atresia/stenosis--a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Epidemiol 22:557-64. 2007
    ..However, this finding is considered only as signal and further studies are needed to confirm or reject this possible association...
  40. ncbi request reprint Population-based case-control teratogenic study of hydroxyprogesterone treatment during pregnancy
    Istvan Dudás
    Foundation for the Community Control of Hereditary Diseases, 1026 Törökvész lejtõ 32, Budapest, Hungary
    Congenit Anom (Kyoto) 46:194-8. 2006
    ....
  41. ncbi request reprint Population-based case-control study of the common cold during pregnancy and congenital abnormalities
    Nandor Acs
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Epidemiol 21:65-75. 2006
    ....
  42. ncbi request reprint Association between maternal panic disorders and pregnancy complications and delivery outcomes
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 124:47-52. 2006
    ....
  43. doi request reprint Maternal characteristics and birth outcomes of pregnant women who had offspring with congenital ear abnormalities - a population-based case-control study
    László Paput
    Department of Otolaryngology, Head and Neck Surgery, State Health Centre, Budapest, Hungary
    J Matern Fetal Neonatal Med 24:1107-14. 2011
    ....
  44. doi request reprint Prevention of neural-tube defects with periconceptional folic acid, methylfolate, or multivitamins?
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Ann Nutr Metab 58:263-71. 2011
    ..To review the main results of intervention trials which showed the efficacy of periconceptional folic acid-containing multivitamin and folic acid supplementation in the prevention of neural-tube defects (NTD)...
  45. doi request reprint The efficacy of antihypertensive treatment in pregnant women with chronic and gestational hypertension: a population-based study
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Hypertens Res 33:460-6. 2010
    ..Antihypertensive treatments were not able to neutralize the harm of severe CH in pregnant women, the antihypertensive treatments were not appropriate and/or effective, or related drug treatments may contribute to these adverse effects...
  46. doi request reprint Congenital abnormalities of 88 children born to mothers who attempted suicide with phenobarbital during pregnany: the use of a disaster epidemiological model for the evaluation of drug teratogenicity
    Gábor Timmermann
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Pharmacoepidemiol Drug Saf 18:815-25. 2009
    ..To study the effect of large doses of phenobarbital used for a suicide attempt during pregnancy for fetuses to estimate the teratogenic potential of phenobarbital...
  47. doi request reprint Birth outcomes of cases with unclassified multiple congenital abnormalities and pregnancy complications in their mothers depending on the number of component defects. Population-based case-control study
    Erzsebet H Puho
    Foundation for the Community Control of Hereditary Diseases, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 48:126-36. 2008
    ..UMCA represent one of the most severe categories of CA. The degree of intrauterine fetal growth retardation depends on number of component CA in UMCA cases...
  48. doi request reprint A possible association between maternal otitis media and ear defect in their offspring
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Am J Otolaryngol 32:203-9. 2011
    ..The possible association between otitis media in pregnancy (OMP) and structural birth defects, that is, congenital abnormalities (CAs), in their offspring has not been studied...
  49. ncbi request reprint No association between periconceptional multivitamin supplementation and risk of multiple congenital abnormalities: a population-based case-control study
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Am J Med Genet A 140:2469-77. 2006
    ..In conclusion, our observational case-control study did not detect a folic acid containing multivitamins during the early pregnancy as a risk factor for MCAs...
  50. pmc A study of the risk of mental retardation among children of pregnant women who have attempted suicide by means of a drug overdose
    Dora Petik
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    J Inj Violence Res 4:10-9. 2012
    ..The aim of the study was to estimate the effect on the fetal development of high doses of prescription drugs taken as a suicide attempt during pregnancy...
  51. ncbi request reprint High fever-related maternal diseases as possible causes of multiple congenital abnormalities: a population-based case-control study
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 79:544-51. 2007
    ..Multiple congenital abnormalities (MCAs) represent the most severe category of structural birth defects; therefore, we decided to evaluate the possible etiological factors for MCAs...
  52. ncbi request reprint No teratogenic effect of prenoxdiazine: a population-based case-control study
    Zoltán Bártfai
    Department of Respiratory Medicine, Semmelweis Medical University, Budapest, Hungary
    Congenit Anom (Kyoto) 47:16-21. 2007
    ..2) or in any group of congenital abnormalities. Treatment with prenoxdiazine during pregnancy did not have any teratogenic risk to the fetus. Thus, prenoxdiazine treatment in pregnant women with an unproductive cough may be beneficial...
  53. ncbi request reprint A population-based case-control teratological study of oral nystatin treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology, National Center for Epidemiology Budapest, Hungary
    Scand J Infect Dis 35:830-5. 2003
    ..The conclusion of the study is that treatment with oral nystatin during pregnancy presents little teratogenic risk to the foetus, but the possible association between hypospadias and nystatin needs further study...
  54. ncbi request reprint Preterm birth reduction after clotrimazole treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Törökvészlejto 32, 1026 Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 116:157-63. 2004
    ..Thus the objective of this secondary analysis in the expanded data set was to evaluate potential confounders and to examine the possible interaction of clotrimazole with other drugs...
  55. doi request reprint Teratogenic potential of tribenoside, a drug for the treatment of haemorrhoids and varicose veins--a population-based case--control study
    Tamás Kubicsek
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Reprod Toxicol 31:464-9. 2011
    ..In conclusion TT in pregnant women associated with a higher risk of congenital hydrocephalus in their children, however, this finding is based on only 4 cases therefore requires further confirmation in future studies...
  56. ncbi request reprint Short-term paracetamol therapy during pregnancy and a lower rate of preterm birth
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Paediatr Perinat Epidemiol 19:106-11. 2005
    ..01). The possible preterm birth protective effect of paracetamol may be associated with paracetamol-induced reduction of prostacyclin production in pregnant women. The clinical relevance of these findings needs further studies...
  57. doi request reprint Efficacy of medical care of epileptic pregnant women based on the rate of congenital abnormalities in their offspring
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Congenit Anom (Kyoto) 51:34-42. 2011
    ..The efficacy of special medical care of epileptic pregnant women was not shown on the basis of decrease in the rate of CAs in the offspring of epileptic pregnant women...
  58. doi request reprint Birth outcomes of cases with left-sided obstructive defects of the heart in the function of maternal socio-demographic factors: a population-based case-control study
    Attila Vereczkey
    Versys Clinics, Human Reproduction Institute, Budapest, Hungary
    J Matern Fetal Neonatal Med 25:2536-41. 2012
    ..To evaluate the birth outcomes and maternal variables of cases with different types of left-sided obstructive defects (LSOD) of the heart...
  59. doi request reprint Congenital abnormalities in children of 43 pregnant women who attempted suicide with large doses of nitrazepam
    Janos Gidai
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Pharmacoepidemiol Drug Saf 19:175-82. 2010
    ..To evaluate the teratogenic effect of very large doses of nitrazepam in children born to pregnant women who attempted suicide and to check the feasibility of self-poisoning pregnant women model...
  60. ncbi request reprint Increasing total prevalence rate of cases with Down syndrome in Hungary
    Julia Metneki
    Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Eur J Epidemiol 20:525-35. 2005
    ..In addition better ascertainment may also contribute to this increase, but new etiological factors cannot also be excluded...
  61. doi request reprint A possible association of periodontal infectious diseases in pregnant women with isolated orofacial clefts in their children: A population-based case-control study
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 88:466-73. 2010
    ....
  62. doi request reprint The estimation of human teratogenic/fetotoxic risk of exposures to drugs on the basis of Hungarian experience: a critical evaluation of clinical and epidemiological models of human teratology
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Expert Opin Drug Saf 8:283-303. 2009
    ..The risk and benefit of drug use during pregnancy needs a better balance because the teratogenic risk is exaggerated...
  63. doi request reprint Periconceptional folic acid and multivitamin supplementation for the prevention of neural tube defects and other congenital abnormalities
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 85:260-8. 2009
    ....
  64. doi request reprint Hypotension in pregnant women: a population-based case-control study of pregnancy complications and birth outcomes
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Hypertens Res 34:55-61. 2011
    ..49-0.84). In conclusion, a higher risk for CAs and other adverse birth outcomes was not found in the offspring of pregnant women with hypotension, but maternal hypotension was associated with a higher risk of some pregnancy complications...
  65. doi request reprint A possible association between acute infectious diarrhoea in pregnant women and congenital abnormalities in their offspring--a population-based case-control study
    Nandor Acs
    Second Department of Obstetrics and Gynaecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Scand J Infect Dis 42:359-67. 2010
    ..A possible explanation for the association of IDP with higher risk for some specific CAs may be the high fever in IDP...
  66. doi request reprint Association between uterus uni/bicornis in pregnant women and postural deformities in their offspring
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Am J Obstet Gynecol 205:560.e1-6. 2011
    ..The objective of the investigation was to study the possible association between uterus uni- or bicornis in pregnant women and structural birth defects (ie, congenital abnormalities) in their offspring...
  67. ncbi request reprint Maternal use of nutritional supplements during the first month of pregnancy and decreased risk of Down's syndrome: case-control study
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Nutrition 21:698-704; discussion 774. 2005
    ..We studied the association between the use of nutritional supplements during the first gestational month and the origin of Down's syndrome...
  68. ncbi request reprint Hungarian cohort-controlled trial of periconceptional multivitamin supplementation shows a reduction in certain congenital abnormalities
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Birth Defects Res A Clin Mol Teratol 70:853-61. 2004
    ..A controlled cohort trial was designed to confirm or deny these results...
  69. ncbi request reprint Birth characteristics of different ocular congenital abnormalities in hungary
    Gábor Vogt
    Hospital and Central Outpatients Clinics of the Hungarian State Railways, Budapest, Hungary
    Ophthalmic Epidemiol 13:159-66. 2006
    ..The aim of the study was to estimate the prevalence at birth of different ocular congenital abnormalities and to describe their birth characteristics in Hungary...
  70. ncbi request reprint Association of very high Hungarian rate of preterm births with cervical incompetence in pregnant women
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Cent Eur J Public Health 18:8-15. 2010
    ....
  71. doi request reprint No association between maternal recurrent genital herpes in pregnancy and higher risk for congenital abnormalities
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Acta Obstet Gynecol Scand 87:292-9. 2008
    ..To study the possible links between recurrent symptomatic genital herpes during pregnancy and risk for congenital abnormalities (CAs)...
  72. ncbi request reprint Protective effect of hyperemesis gravidarum for nonsyndromic oral clefts
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Obstet Gynecol 101:737-44. 2003
    ..To evaluate whether hyperemesis gravidarum is associated with a decreased risk for nonsyndromic oral clefts and to examine the relationship between hyperemesis gravidarum, birth weight, and gestational age...
  73. ncbi request reprint A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy
    Erika Eros
    Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 101:147-54. 2002
    ..To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)...
  74. pmc Attempted suicide and pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    J Inj Violence Res 3:45-54. 2011
    ..This system was appropriate to describe the characteristics of these pregnant women as a secondary finding from this model...
  75. ncbi request reprint Periconceptional multivitamin supplementation and multimalformed offspring
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Obstet Gynecol 102:1255-61. 2003
    ..To study the human teratogenic risk of a folic acid-containing multivitamin...
  76. ncbi request reprint A case-control teratological study of vaginal natamycin treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Torokvesz Lejto 32, 1026 Budapest, Hungary
    Reprod Toxicol 17:387-91. 2003
    ..01), though mean gestational age was shorter. The conclusion of this study is that the treatment with vaginal natamycin during pregnancy presents no detectable teratogenic risk to the fetus...
  77. ncbi request reprint Possible association between different congenital abnormalities and use of different sulfonamides during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Congenit Anom (Kyoto) 44:79-86. 2004
    ..9, 1.1-13.8). Thus, maternal treatment of sulfamethoxydiazine may cause ventricular septal defect, while sulfathiourea may induce clubfoot; however, further studies are needed to verify or reject these associations...
  78. doi request reprint Specified critical period of different congenital abnormalities: a new approach for human teratological studies
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Congenit Anom (Kyoto) 48:103-9. 2008
    ..The author of this Commentary proposes a detailed database for this approach for discussion because a consensus may be achieved only after the confirmation or modification of these critical periods...
  79. ncbi request reprint Periconceptional folic acid/multivitamin supplementation and twin pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Am J Obstet Gynecol 191:790-4. 2004
    ..These findings were confirmed by US and Swedish studies, but not in the Chinese population. The aim of this analysis is to evaluate this possible association in a population-based data set...
  80. ncbi request reprint Occupational epidemiological study of workers in an acrylonitrile using factory with particular attention to cancers and birth defects
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Torokvesz Lejto 32, Budapest 1026, Hungary
    Mutat Res 547:79-89. 2004
    ..In conclusion, our study did not indicate the carcinogenic, mutagenic and teratogenic effect of acrylonitrile among workers using this chemical in the factory...
  81. ncbi request reprint Tolnaftate spray treatment during pregnancy
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Torokvesz Lejto 32, 1026 Budapest, Hungary
    Reprod Toxicol 18:443-4. 2004
    ..Thus, it is a signal for the potential teratogenic risk of tolnaftate in a case-control study, though the number of cases and controls were limited. Therefore, international collaboration is needed for the final conclusion...
  82. ncbi request reprint Periconceptional clinics: a medical health care infrastructure of new genetics
    Andrew E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Fetal Diagn Ther 20:515-8. 2005
    ..Periconceptional clinics seem to be appropriate for the starting point for the primary prevention of common complex diseases as well...
  83. ncbi request reprint Inverse association between severe nausea and vomiting in pregnancy and some congenital abnormalities
    Andrew E Czeizel
    Am J Med Genet A 140:453-62. 2006
    ..Thus in this study the mothers of cases with congenital abnormalities were 26% less likely to have had severe nausea and vomiting in early pregnancy than the mothers of population controls without congenital abnormalities...
  84. ncbi request reprint Aspirin use during early pregnancy and the risk of congenital abnormalities: a population-based case-control study
    Bente Nørgård
    Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Am J Obstet Gynecol 192:922-3. 2005
    ..We examined the risk of selected congenital abnormalities in a large case-control dataset from Hungary and found no increased risk of such congenital abnormalities...
  85. ncbi request reprint Outcomes in pregnancy
    Andrew E Czeizel
    Lancet 359:2204-5. 2002
  86. ncbi request reprint Birth weight and gestational age of newborns with cleft lip with or without cleft palate and with isolated cleft palate
    Diego F Wyszynski
    Boston University School of Medicine, 715 Albany Street, L 320, Boston, MA 02118, USA
    J Clin Pediatr Dent 27:185-90. 2003
    ..Speculations on a relationship between these findings and the presence of oral clefts are presented...
  87. ncbi request reprint Use of phenytoin, phenobarbital, or diazepam during pregnancy and risk of congenital abnormalities: a case-time-control study
    Dorte Kjaer
    The Danish Epidemiology Science Centre, Department of Epidemiology, Institute of Public Health, University of Aarhus, Aarhus, Denmark
    Pharmacoepidemiol Drug Saf 16:181-8. 2007
    ..We studied congenital abnormalities following exposure to phenytoin, phenobarbital, and diazepam in early pregnancy, i.e., second and third month, compared to mid-pregnancy, i.e., fifth and sixth month of pregnancy...
  88. doi request reprint Acetaminophen use during pregnancy: effects on risk for congenital abnormalities
    Cristina Rebordosa
    Autonomous University of Barcelona, Barcelona, Spain
    Am J Obstet Gynecol 198:178.e1-7. 2008
    ..We evaluated if acetaminophen, one of the most frequently used drugs among pregnant women is associated with an increased prevalence of congenital abnormalities...
  89. ncbi request reprint Risk of congenital abnormalities in children born to women with ulcerative colitis: a population-based, case-control study
    Bente Nørgård
    Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Am J Gastroenterol 98:2006-10. 2003
    ..We therefore examined the risk of congenital abnormalities in children born to women with ulcerative colitis...
  90. ncbi request reprint Maternal herpes labialis in pregnancy and neural tube defects
    Bente Nørgård
    Department of Clinical Epidemiology, Aarhus University Hospital, Denmark
    Dev Med Child Neurol 48:674-6. 2006
    ..19 (95% confidence interval [CI] 0.68-2.06), and in the entire pregnancy was OR 0.94 (95% CI 0.61-1.44). Self-reported maternal herpes labialis during pregnancy was not associated with a substantially increased risk of NTDs in infants...
  91. ncbi request reprint An evaluation of maternal illnesses in the origin of neural-tube defects
    Erika Medveczky
    International Peto Institute, Kútvölgyi út 6, 1125 Budapest, Hungary
    Arch Gynecol Obstet 270:244-51. 2004
    ..The objective of the study was to estimate risk of acute and chronic maternal diseases during pregnancy in the origin of neural-tube defects...
  92. ncbi request reprint A population-based case-control study of isolated ocular coloboma
    Gábor Vogt
    Hospital and Central Outpatients Clinics of the Hungarian State Railways, Podmaniczky u 111, H 1062 Budapest, Hungary
    Ophthalmic Epidemiol 12:191-7. 2005
    ..To attempt the detection of possible etiological factors in the origin of isolated ocular, mainly iris coloboma...
  93. ncbi request reprint Maternal use of oral contraceptives and risk of hypospadias - a population-based case-control study
    Pia Wogelius
    Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Eur J Epidemiol 21:777-81. 2006
    ..83 (95% CI: 0.46-1.50). Our data showed that self-reported maternal use of oral contraceptives during pregnancy was not associated with an increased risk of hypospadias in the offspring...