Barna Budai

Summary

Country: Hungary

Publications

  1. doi request reprint The use of high dose d,l-leucovorin in first-line bevacizumab+mFOLFIRI treatment of patients with metastatic colorectal cancer may enhance the antiangiogenic effect of bevacizumab
    B Budai
    National Institute of Oncology, Budapest, Hungary
    Angiogenesis 16:113-21. 2013
  2. doi request reprint Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab
    Barna Budai
    National Institute of Oncology, Semmelweis University, Budapest, Hungary
    Pharmacogenet Genomics 22:69-72. 2012
  3. ncbi request reprint [The clinical importance of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the 5-fluoropyrimidine-based therapy of metastatic colorectal tumours]
    Barna Budai
    Országos Onkológiai Intézet, Budapest 1122, Hungary
    Magy Onkol 48:253-7. 2004
  4. doi request reprint Enhanced 5-fluorouracil cytotoxicity in high cyclooxygenase-2 expressing colorectal cancer cells and xenografts induced by non-steroidal anti-inflammatory drugs via downregulation of dihydropyrimidine dehydrogenase
    Andrea Réti
    Department of Clinical Research, National Institute of Oncology, Budapest, Hungary
    Cancer Chemother Pharmacol 66:219-27. 2010
  5. ncbi request reprint Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil
    Erika Hitre
    National Institute of Oncology, Budapest, Hungary
    Pharmacogenet Genomics 15:723-30. 2005
  6. doi request reprint Enhancement of 5-fluorouracil efficacy on high COX-2 expressing HCA-7 cells by low dose indomethacin and NS-398 but not on low COX-2 expressing HT-29 cells
    Andrea Réti
    National Institute of Oncology, Budapest, Hungary
    Pathol Oncol Res 15:335-44. 2009
  7. ncbi request reprint [Prognostic significance of sex steroid and hypophyseal hormones in head and neck squamous cell carcinoma]
    Eva Remenar
    Fej Nyak, Allcsont, Laser és Helyreállító Plasztikai Sebészeti Osztály, Országos Onkológiai Intézet, Budapest 1122, Hungary
    Magy Onkol 47:155-9. 2003
  8. pmc SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer
    Viktor Komlósi
    School of PhD Studies, Pathological Sciences, Semmelweis University, Budapest, Hungary
    BMC Cancer 10:525. 2010
  9. ncbi request reprint Increase of hypophyseal hormone levels in male head and neck cancer patients
    Eva Remenar
    Department of Head and Neck, Laser and Reconstructive Plastic Surgery, National Institute of Oncology, Budapest, H 1122, Hungary
    Pathol Oncol Res 13:341-4. 2007
  10. ncbi request reprint Prognostic significance of the thymidylate biosynthetic enzymes in human colorectal tumors
    Judit Kralovanszky
    National Institute of Oncology, Semmelweis University, Budapest, Hungary
    Oncology 62:167-74. 2002

Collaborators

Detail Information

Publications17

  1. doi request reprint The use of high dose d,l-leucovorin in first-line bevacizumab+mFOLFIRI treatment of patients with metastatic colorectal cancer may enhance the antiangiogenic effect of bevacizumab
    B Budai
    National Institute of Oncology, Budapest, Hungary
    Angiogenesis 16:113-21. 2013
    ..These findings need to be further confirmed in a randomized controlled prospective trial...
  2. doi request reprint Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab
    Barna Budai
    National Institute of Oncology, Semmelweis University, Budapest, Hungary
    Pharmacogenet Genomics 22:69-72. 2012
    ..Bevacizumab-related hypertension might be a predictive marker of treatment efficacy (P=0.0002 for OS) in the case of wild (CC) SHMT1 1420 genotypes only...
  3. ncbi request reprint [The clinical importance of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the 5-fluoropyrimidine-based therapy of metastatic colorectal tumours]
    Barna Budai
    Országos Onkológiai Intézet, Budapest 1122, Hungary
    Magy Onkol 48:253-7. 2004
    ..015). Determination of MTHFR C677T polymorphism has prognostic value in case of patients with metastatic colorectal cancer receiving 5-fluoropyrimidine-based therapy, and may help in designing the individual (group) tailored therapy...
  4. doi request reprint Enhanced 5-fluorouracil cytotoxicity in high cyclooxygenase-2 expressing colorectal cancer cells and xenografts induced by non-steroidal anti-inflammatory drugs via downregulation of dihydropyrimidine dehydrogenase
    Andrea Réti
    Department of Clinical Research, National Institute of Oncology, Budapest, Hungary
    Cancer Chemother Pharmacol 66:219-27. 2010
    ....
  5. ncbi request reprint Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil
    Erika Hitre
    National Institute of Oncology, Budapest, Hungary
    Pharmacogenet Genomics 15:723-30. 2005
    ....
  6. doi request reprint Enhancement of 5-fluorouracil efficacy on high COX-2 expressing HCA-7 cells by low dose indomethacin and NS-398 but not on low COX-2 expressing HT-29 cells
    Andrea Réti
    National Institute of Oncology, Budapest, Hungary
    Pathol Oncol Res 15:335-44. 2009
    ....
  7. ncbi request reprint [Prognostic significance of sex steroid and hypophyseal hormones in head and neck squamous cell carcinoma]
    Eva Remenar
    Fej Nyak, Allcsont, Laser és Helyreállító Plasztikai Sebészeti Osztály, Országos Onkológiai Intézet, Budapest 1122, Hungary
    Magy Onkol 47:155-9. 2003
    ..to investigate the clinical outcome of HNSCC patients, and their hormonal status...
  8. pmc SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer
    Viktor Komlósi
    School of PhD Studies, Pathological Sciences, Semmelweis University, Budapest, Hungary
    BMC Cancer 10:525. 2010
    ..The serum total homocysteine (HCY), marker of folate metabolism was also investigated...
  9. ncbi request reprint Increase of hypophyseal hormone levels in male head and neck cancer patients
    Eva Remenar
    Department of Head and Neck, Laser and Reconstructive Plastic Surgery, National Institute of Oncology, Budapest, H 1122, Hungary
    Pathol Oncol Res 13:341-4. 2007
    ..The significant increase in FSH and LH serum levels, observed only in the cancer patients, indicates that these hormones may play a role in the development and/or progression of HNSCC...
  10. ncbi request reprint Prognostic significance of the thymidylate biosynthetic enzymes in human colorectal tumors
    Judit Kralovanszky
    National Institute of Oncology, Semmelweis University, Budapest, Hungary
    Oncology 62:167-74. 2002
    ..Multivariate analysis showed that among the variables tested, beside Dukes' stage, TS and TK activities were significant prognostic factors for the overall survival of colorectal cancer patients...
  11. ncbi request reprint Co-inhibition of cyclooxygenase-2 and dihydropyrimidine dehydrogenase by non-steroidal anti-inflammatory drugs in tumor cells and xenografts
    Andrea Réti
    National Institute of Oncology, Rath Gy str 7 9, Budapest H 1122, Hungary
    Anticancer Res 29:3095-101. 2009
    ..We previously showed that NSAIDs increased 5-FU sensitivity only in high COX-2-expressing cancer cells...
  12. ncbi request reprint [Potentiation of 5-fluorouracil efficacy. Molecular mechanisms playing a role in the cytotoxic action of 5-fluorouracil and 5-ethyl-2'-deoxyuridine (EUdR) combination]
    Csilla Katona
    Onkoradiológia, Uzsoki utcai Kórház, Budapest, Hungary
    Magy Onkol 48:243-51. 2004
    ..Pharmacologic modulation of 5-fluorouracil (5-FU) metabolism provides a possibility for the enhancement of its clinical efficacy...
  13. pmc Effects of the lactase 13910 C/T and calcium-sensor receptor A986S G/T gene polymorphisms on the incidence and recurrence of colorectal cancer in Hungarian population
    Krisztian Bacsi
    First Department of Medicine, Semmelweis University, Budapest 1083 Korányi Sándor u 2 a, Hungary
    BMC Cancer 8:317. 2008
    ....
  14. doi request reprint Microanalytical method development for Fe, Cu and Zn determination in colorectal cancer cells
    Zsófia Polgári
    Laboratory of Environmental Chemistry and Bioanalytics, Department of Analytical Chemistry, Institute of Chemistry, Eotvos Lorand University, H 1518, P O Box 32, Budapest, Hungary
    Talanta 85:1959-65. 2011
    ..Pronounced differences in the iron uptake compared to the iron supply (inorganic vs. organic chelated as well as iron(II) vs. iron(III)) were observed in the case of cell lines incubated in FCS-free medium...
  15. ncbi request reprint [Pharmacogenetic studies on the prediction of efficacy and toxicity of fluoropyrimidine-based adjuvant therapy in colorectal cancer]
    Judit Kralovanszky
    Országos Onkológiai Intézet, 1122 Budapest
    Magy Onkol 51:113-25. 2007
    ..According to the Cox multivariate analysis the combination of germline TS polymorphisms and DPD activity is/an independent prognostic marker of survival in CRC patients treated with adjuvant 5-FU therapy...
  16. ncbi request reprint [Serum levels of sex steroid and pituitary hormones in chronic alcoholics and head and neck cancer patients as compared to normal controls]
    Eva Remenar
    Országos Onkológiai Intézet, Fej Nyak, Allcsont, Laser és Helyreállító Plasztikai Sebészeti Osztály, Budapest, Hungary
    Magy Onkol 46:329-32. 2002
    ..However, only a few percent of all alcoholics develop head and neck cancer...
  17. ncbi request reprint High and low affinity receptors mediate growth effects of gastrin and gastrin-Gly on DLD-1 human colonic carcinoma cells
    Shawn Ahmed
    Creighton University School of Medicine, Department of Biomedical Sciences, 2500 California Plaza, Omaha, NE 68137, USA
    FEBS Lett 556:199-203. 2004
    ..The binding profiles of the peptides tested suggest that these sites are different from previously identified wild-type and mutant CCK(1) or CCK(2) receptors...