J H Humphrey

Summary

Publications

  1. pmc Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal study
    Melissa F Miller
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    BMC Infect Dis 6:1. 2006
  2. pmc Mother to child transmission of HIV among Zimbabwean women who seroconverted postnatally: prospective cohort study
    Jean H Humphrey
    ZVITAMBO Project, Harare, Zimbabwe
    BMJ 341:c6580. 2010
  3. ncbi request reprint HIV incidence among post-partum women in Zimbabwe: risk factors and the effect of vitamin A supplementation
    Jean H Humphrey
    Johns Hopkins Bloomberg School of Public Health, Department of International Health, Baltimore, Maryland, USA
    AIDS 20:1437-46. 2006
  4. ncbi request reprint Effects of a single large dose of vitamin A, given during the postpartum period to HIV-positive women and their infants, on child HIV infection, HIV-free survival, and mortality
    Jean H Humphrey
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Infect Dis 193:860-71. 2006
  5. pmc HIV-1 and HIV-2 prevalence and associated risk factors among postnatal women in Harare, Zimbabwe
    J H Humphrey
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Epidemiol Infect 135:933-42. 2007
  6. ncbi request reprint Adoption of safer infant feeding and postpartum sexual practices and their relationship to maternal HIV status and risk of acquiring HIV in Zimbabwe
    N V Tavengwa
    ZVITAMBO Project, Harare, Zimbabwe
    Trop Med Int Health 12:97-106. 2007
  7. ncbi request reprint Effect of postpartum maternal or neonatal vitamin A supplementation on infant mortality among infants born to HIV-negative mothers in Zimbabwe
    Lucie C Malaba
    Department of Nutrition, University of Zimbabwe, Harare, Zimbabwe
    Am J Clin Nutr 81:454-60. 2005
  8. ncbi request reprint Vitamin A supplementation of young infants
    J H Humphrey
    Center for Human Nutrition, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
    Lancet 356:422-4. 2000
  9. ncbi request reprint Mortality and morbidity among postpartum HIV-positive and HIV-negative women in Zimbabwe: risk factors, causes, and impact of single-dose postpartum vitamin A supplementation
    Partson Zvandasara
    Department of Obstetrics and Gynaecology, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe
    J Acquir Immune Defic Syndr 43:107-16. 2006
  10. ncbi request reprint Vitamin A and the nursing mother-infant dyad: evidence for intervention
    Rebecca J Stoltzfus
    Center for Human Nutrition, Department of International Health, The Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
    Adv Exp Med Biol 503:39-47. 2002

Collaborators

Detail Information

Publications26

  1. pmc Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal study
    Melissa F Miller
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    BMC Infect Dis 6:1. 2006
    ..Anemia is common in HIV infection and independently associated with disease progression and mortality. The pathophysiology of HIV-related anemia is not well understood especially in infancy...
  2. pmc Mother to child transmission of HIV among Zimbabwean women who seroconverted postnatally: prospective cohort study
    Jean H Humphrey
    ZVITAMBO Project, Harare, Zimbabwe
    BMJ 341:c6580. 2010
    ....
  3. ncbi request reprint HIV incidence among post-partum women in Zimbabwe: risk factors and the effect of vitamin A supplementation
    Jean H Humphrey
    Johns Hopkins Bloomberg School of Public Health, Department of International Health, Baltimore, Maryland, USA
    AIDS 20:1437-46. 2006
    ..To test whether post-partum vitamin A supplementation can reduce incident HIV among post-partum women and identify risk factors for HIV incidence...
  4. ncbi request reprint Effects of a single large dose of vitamin A, given during the postpartum period to HIV-positive women and their infants, on child HIV infection, HIV-free survival, and mortality
    Jean H Humphrey
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Infect Dis 193:860-71. 2006
    ..We investigated the effect that single-large-dose maternal/neonatal vitamin A supplementation has on MTCT, HIV-free survival, and mortality in HIV-exposed infants...
  5. pmc HIV-1 and HIV-2 prevalence and associated risk factors among postnatal women in Harare, Zimbabwe
    J H Humphrey
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Epidemiol Infect 135:933-42. 2007
    ..Prevalent HIV-1 infection is associated with financial insecurity and weak psychosocial support. The ZVITAMBO study apparently spanned the peak of the HIV-1 epidemic among reproductive women in Harare...
  6. ncbi request reprint Adoption of safer infant feeding and postpartum sexual practices and their relationship to maternal HIV status and risk of acquiring HIV in Zimbabwe
    N V Tavengwa
    ZVITAMBO Project, Harare, Zimbabwe
    Trop Med Int Health 12:97-106. 2007
    ..To examine the relationships between maternal knowledge and concern about HIV status, adoption of preventive practices and risk of acquiring HIV in Zimbabwe...
  7. ncbi request reprint Effect of postpartum maternal or neonatal vitamin A supplementation on infant mortality among infants born to HIV-negative mothers in Zimbabwe
    Lucie C Malaba
    Department of Nutrition, University of Zimbabwe, Harare, Zimbabwe
    Am J Clin Nutr 81:454-60. 2005
    ....
  8. ncbi request reprint Vitamin A supplementation of young infants
    J H Humphrey
    Center for Human Nutrition, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
    Lancet 356:422-4. 2000
    ..Furthermore, the minimum requirement of vitamin A given to infants is 237 mcmol...
  9. ncbi request reprint Mortality and morbidity among postpartum HIV-positive and HIV-negative women in Zimbabwe: risk factors, causes, and impact of single-dose postpartum vitamin A supplementation
    Partson Zvandasara
    Department of Obstetrics and Gynaecology, University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe
    J Acquir Immune Defic Syndr 43:107-16. 2006
    ..Vitamin A deficiency is common among women in resource-poor countries and is associated with greater mortality during HIV...
  10. ncbi request reprint Vitamin A and the nursing mother-infant dyad: evidence for intervention
    Rebecca J Stoltzfus
    Center for Human Nutrition, Department of International Health, The Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
    Adv Exp Med Biol 503:39-47. 2002
    ..In sum, the probable benefits of improving the vitamin A status of the breastfeeding mother and her baby are substantial, but to achieve these benefits, more aggressive interventions will be needed...
  11. ncbi request reprint Child mortality according to maternal and infant HIV status in Zimbabwe
    Edmore Marinda
    ZVITAMBO Project, Harare, Zimbabwe
    Pediatr Infect Dis J 26:519-26. 2007
    ..HIV causes substantial mortality among African children but there is limited data on how this is influenced by maternal or infant infection status and timing...
  12. ncbi request reprint Early exclusive breastfeeding reduces the risk of postnatal HIV-1 transmission and increases HIV-free survival
    Peter J Iliff
    ZVITAMBO Project, Borrowdale, Harare, Zimbabwe
    AIDS 19:699-708. 2005
    ....
  13. ncbi request reprint Neonatal vitamin A supplementation: effect on development and growth at 3 y of age
    J H Humphrey
    Center for Human Nutrition, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
    Am J Clin Nutr 68:109-17. 1998
    ..68 cm, P < 0.05), over the first 3 y of life. This study provides no evidence that neonatal vitamin A supplementation is associated with biologically significant adverse growth or developmental sequelae...
  14. ncbi request reprint HIV-positive poor women may stop breast-feeding early to protect their infants from HIV infection although available replacement diets are grossly inadequate
    Kevin M Lunney
    ZVITAMBO Project, Harare, Zimbabwe
    J Nutr 138:351-7. 2008
    ..As reflected in the new World Health Organization guidance, HIV-positive mothers should continue breastfeeding their infants beyond 6 mo if replacement feeding is still not acceptable, feasible, affordable, sustainable, and safe...
  15. ncbi request reprint An education and counseling program for preventing breast-feeding-associated HIV transmission in Zimbabwe: design and impact on maternal knowledge and behavior
    Ellen G Piwoz
    ZVITAMBO Project, Harare, Zimbabwe
    J Nutr 135:950-5. 2005
    ..Formative research aided in the design of a culturally sensitive intervention. The intervention increased relevant knowledge and improved feeding practices among women who primarily did not know their HIV status...
  16. ncbi request reprint Total body iron in HIV-positive and HIV-negative Zimbabwean newborns strongly predicts anemia throughout infancy and is predicted by maternal hemoglobin concentration
    Melissa F Miller
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
    J Nutr 133:3461-8. 2003
    ..Babies born with low birthweight or to mothers with low hemoglobin are born with less TBI, which confers a substantially greater risk of anemia from 3 to 12 mo of age...
  17. doi request reprint Effect of early exclusive breastfeeding on morbidity among infants born to HIV-negative mothers in Zimbabwe
    Ai Koyanagi
    Johns Hopkins Bloomberg School of Public Health, Department of International Health, Baltimore MD, USA
    Am J Clin Nutr 89:1375-82. 2009
    ..No studies conducted in Africa have reported any benefits of EBF for infants born to HIV-negative women...
  18. pmc Heat treatment of expressed breast milk is a feasible option for feeding HIV-exposed, uninfected children after 6 months of age in rural Zimbabwe
    Mduduzi N N Mbuya
    ZVITAMBO Project, Harare, Zimbabwe
    J Nutr 140:1481-8. 2010
    ..EHT provides a strategy for improving the diets of HIV-exposed but uninfected children after direct breast-feeding has ceased...
  19. doi request reprint Associations between breast milk viral load, mastitis, exclusive breast-feeding, and postnatal transmission of HIV
    Kevin M Lunney
    University of Maryland School of Medicine, Department of Epidemiology and Preventive Medicine, Baltimore, USA
    Clin Infect Dis 50:762-9. 2010
    ..The mechanism of exclusive breast-feeding protection is unknown but is hypothesized to be mediated through reduced mastitis...
  20. doi request reprint Improved HIV-1 incidence estimates using the BED capture enzyme immunoassay
    John W Hargrove
    ZVITAMBO Project, Harare, Zimbabwe
    AIDS 22:511-8. 2008
    ..To validate the BED capture enzyme immunoassay for HIV-1 subtype C and to derive adjustments facilitating estimation of HIV-1 incidence from cross-sectional surveys...
  21. pmc Postpartum plasma CD4 change in HIV-positive women: implications for timing of HAART initiation
    Ai Koyanagi
    Johns Hopkins Bloomberg School of Public Health, Department of International Health, Baltimore, Maryland, USA
    AIDS Res Hum Retroviruses 26:547-52. 2010
    ..27 (95% CI 1.85-14.96) times higher than those with CD4 <350 at delivery but >or=350 cells/microl at 6 weeks. The use of CD4 counts immediately postpartum to define HAART eligibility may lead to substantial misclassification...
  22. ncbi request reprint Effect of maternal and neonatal vitamin A supplementation and other postnatal factors on anemia in Zimbabwean infants: a prospective, randomized study
    Melissa F Miller
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    Am J Clin Nutr 84:212-22. 2006
    ..Anemia is prevalent in infants in developing countries. Its etiology is multifactorial and includes vitamin A deficiency...
  23. ncbi request reprint Maternal Herpes simplex virus type 2 infection, syphilis and risk of intra-partum transmission of HIV-1: results of a case control study
    Frances M Cowan
    Centre for Sexual Health and HIV Research, Royal Free and University College Medical School, University College London, UK
    AIDS 22:193-201. 2008
    ..The effect of these infections on intra-partum mother-to-child-transmission (MTCT) of HIV-1 is unknown...
  24. pmc The impact of safer breastfeeding practices on postnatal HIV-1 transmission in Zimbabwe
    Ellen G Piwoz
    Center for Nutrition, Academy for Educational Development, Washington, DC, USA
    Am J Public Health 97:1249-54. 2007
    ....
  25. ncbi request reprint Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe
    Ellen G Piwoz
    Academy for Educational Development, Washington DC, USA
    AIDS 20:1981-4. 2006
    ..23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population...
  26. ncbi request reprint Genetic variants in nonclassical major histocompatibility complex class I human leukocyte antigen (HLA)-E and HLA-G molecules are associated with susceptibility to heterosexual acquisition of HIV-1
    Julie Lajoie
    Laboratoire d Immunogénétique, Hôpital Notre Dame du Centre Hospitalier de l Université de Montréal, Canada
    J Infect Dis 193:298-301. 2006
    ..In conclusion, HLA-E and HLA-G polymorphisms can independently and synergistically influence susceptibility to heterosexual acquisition of HIV-1...