Laura A E Hughes

Summary

Publications

  1. pmc Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP)
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e18571. 2011
  2. doi request reprint Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study
    Laura A E Hughes
    Department of Epidemiology, Faculty of Health Medicine and Life Science, MaastrichtUniversity, Maastricht, The Netherlands
    Am J Epidemiol 174:1127-39. 2011
  3. doi request reprint Dietary flavonol, flavone and catechin intake and risk of colorectal cancer in the Netherlands Cohort Study
    Colinda C J M Simons
    Department of Epidemiology, School for Oncology and Developmental Biology GROW, Maastricht University, Maastricht, The Netherlands
    Int J Cancer 125:2945-52. 2009
  4. doi request reprint Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Int J Epidemiol 39:1333-44. 2010
  5. pmc Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    PLoS ONE 4:e7951. 2009
  6. doi request reprint Physical activity, occupational sitting time, and colorectal cancer risk in the Netherlands cohort study
    Colinda C J M Simons
    Department of Epidemiology, Faculty of Health, Medicine, and Life Sciences, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Am J Epidemiol 177:514-30. 2013
  7. doi request reprint The CpG island methylator phenotype in colorectal cancer: progress and problems
    Laura A E Hughes
    Dept of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, 6200MD Maastricht, The Netherlands
    Biochim Biophys Acta 1825:77-85. 2012
  8. doi request reprint Longitudinal changes in BMI in older adults are associated with meat consumption differentially, by type of meat consumed
    Anne M J Gilsing
    Department of Epidemiology, School for Oncology and Developmental Biology, Maastricht University, Maastricht, Netherlands
    J Nutr 142:340-9. 2012
  9. ncbi request reprint Higher dietary flavone, flavonol, and catechin intakes are associated with less of an increase in BMI over time in women: a longitudinal analysis from the Netherlands Cohort Study
    Laura A E Hughes
    Department of Epidemiology, School for Oncology and Developmental Biology, Nutrition and Toxicology Research Institute, Maastricht University, Maastricht, Netherlands NUTRIM
    Am J Clin Nutr 88:1341-52. 2008
  10. ncbi request reprint Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Int J Epidemiol 41:1060-72. 2012

Detail Information

Publications12

  1. pmc Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP)
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e18571. 2011
    ..We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC)...
  2. doi request reprint Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study
    Laura A E Hughes
    Department of Epidemiology, Faculty of Health Medicine and Life Science, MaastrichtUniversity, Maastricht, The Netherlands
    Am J Epidemiol 174:1127-39. 2011
    ..Height was associated with risk of CRC, especially distal colon tumors (highest quintile vs. lowest: HR = 1.53, 95% CI: 1.03, 2.27; P-trend = 0.05), in women only...
  3. doi request reprint Dietary flavonol, flavone and catechin intake and risk of colorectal cancer in the Netherlands Cohort Study
    Colinda C J M Simons
    Department of Epidemiology, School for Oncology and Developmental Biology GROW, Maastricht University, Maastricht, The Netherlands
    Int J Cancer 125:2945-52. 2009
    ..Dietary catechin intake may be associated with a decreased rectal cancer risk in overweight men. Dietary flavonol and catechin intake may be associated with a decreased colorectal cancer risk in normal weight women...
  4. doi request reprint Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Int J Epidemiol 39:1333-44. 2010
    ..Energy restriction during childhood and adolescence is suggested to lower colorectal cancer (CRC) risk. We investigated this in the Netherlands Cohort Study...
  5. pmc Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    PLoS ONE 4:e7951. 2009
    ..Within the Netherlands Cohort Study on diet and cancer, we investigated the association between early life energy restriction and risk of subsequent CRC characterized by the (promoter) CpG island methylation phenotype (CIMP)...
  6. doi request reprint Physical activity, occupational sitting time, and colorectal cancer risk in the Netherlands cohort study
    Colinda C J M Simons
    Department of Epidemiology, Faculty of Health, Medicine, and Life Sciences, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Am J Epidemiol 177:514-30. 2013
    ..59, 95% CI: 0.39, 0.90; P for trend = 0.02). In conclusion, regular long-term physical activity and fewer sitting hours may protect against colon cancer, particularly distal colon cancer; results for rectal cancer were mixed...
  7. doi request reprint The CpG island methylator phenotype in colorectal cancer: progress and problems
    Laura A E Hughes
    Dept of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, 6200MD Maastricht, The Netherlands
    Biochim Biophys Acta 1825:77-85. 2012
    ....
  8. doi request reprint Longitudinal changes in BMI in older adults are associated with meat consumption differentially, by type of meat consumed
    Anne M J Gilsing
    Department of Epidemiology, School for Oncology and Developmental Biology, Maastricht University, Maastricht, Netherlands
    J Nutr 142:340-9. 2012
    ..However, total meat consumption, or factors directly related to total meat intake, was not strongly associated with weight change during the 14-y prospective follow-up in this elderly population...
  9. ncbi request reprint Higher dietary flavone, flavonol, and catechin intakes are associated with less of an increase in BMI over time in women: a longitudinal analysis from the Netherlands Cohort Study
    Laura A E Hughes
    Department of Epidemiology, School for Oncology and Developmental Biology, Nutrition and Toxicology Research Institute, Maastricht University, Maastricht, Netherlands NUTRIM
    Am J Clin Nutr 88:1341-52. 2008
    ..Dietary flavonoids are suggested to have antiobesity effects. Prospective evidence of an association between flavonoids and body mass index (BMI) is lacking in general populations...
  10. ncbi request reprint Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Int J Epidemiol 41:1060-72. 2012
    ..We investigated whether measures of anthropometry differentially influence risk of tumours according to BRAF c.1799T>A p.V600E mutation (BRAF) and microsatellite instability (MSI) status...
  11. doi request reprint Self-reported clothing size as a proxy measure for body size
    Laura A E Hughes
    Department of Epidemiology, School for Oncology and Developmental Biology GROW, Maastricht University, Maastricht, The Netherlands
    Epidemiology 20:673-6. 2009
    ..Few studies have considered the potential utility of clothing size as a predictor of diseases associated with body weight...
  12. doi request reprint Pharmacoepigenomics in colorectal cancer: a step forward in predicting prognosis and treatment response
    Kim M Smits
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, The Netherlands
    Pharmacogenomics 9:1903-16. 2008
    ..This review describes the current knowledge on the prognostic and predictive value of epigenetic markers in colorectal cancer...