Otmar Huber

Summary

Publications

  1. Rennert K, Otto P, Funke H, Huber O, Tomaso H, Mosig A. A human macrophage-hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica. BMC Microbiol. 2016;16:2 pubmed publisher
    ..We developed a suitable tool for more detailed in vitro studies on the immune response upon liver cell infection by F. tularensis. ..
  2. Bloch L, Ndongson Dongmo B, Kusch A, Dragun D, Heller R, Huber O. Real-time monitoring of hypertrophy in HL-1 cardiomyocytes by impedance measurements reveals different modes of growth. Cytotechnology. 2016;68:1897-907 pubmed publisher
    ..Hypertrophic growth was blocked by the PI3K/mTOR inhibitor PI-103. ..
  3. Schiffner R, Bischoff S, Lehmann T, Rakers F, Rupprecht S, Reiche J, et al. Redistribution of Cerebral Blood Flow during Severe Hypovolemia and Reperfusion in a Sheep Model: Critical Role of α1-Adrenergic Signaling. Int J Mol Sci. 2017;18: pubmed publisher
  4. request reprint
    Cindric Vranesic A, Reiche J, Hoischen C, Wohlmann A, Bratsch J, Friedrich K, et al. Characterization of SKAP/kinastrin isoforms: the N-terminus defines tissue specificity and Pontin binding. Hum Mol Genet. 2016;25:2838-2852 pubmed
  5. Wetzel F, Mittag S, Cano Cortina M, Wagner T, Kramer O, Niedenthal R, et al. SUMOylation regulates the intracellular fate of ZO-2. Cell Mol Life Sci. 2017;74:373-392 pubmed publisher
    ..From these data we conclude that SUMOylation affects the intracellular localization of ZO-2 and its regulatory role on GSK3? and ?-catenin signaling activity. ..