Wesley Hsu

Summary

Publications

  1. doi request reprint Role of cancer stem cells in spine tumors: review of current literature
    Wesley Hsu
    Department of Neurosurgery, Wake Forest Baptist Medical Center, Winston Salem, NC 27157 1029, USA
    Neurosurgery 71:117-25. 2012
  2. doi request reprint Animal model of intramedullary spinal cord glioma using human glioblastoma multiforme neurospheres
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Neurosurg Spine 16:315-9. 2012
  3. doi request reprint Strategies to avoid wrong-site surgery during spinal procedures
    Wesley Hsu
    Department of Neurosurgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina 27157 1029, USA
    Neurosurg Focus 31:E5. 2011
  4. doi request reprint Image-guided, endoscopic, transcervical resection of cervical chordoma
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 12:431-5. 2010
  5. ncbi request reprint Three-level en bloc spondylectomy for chordoma
    Michelle J Clarke
    Department of Neurosurgery, Mayo Clinic, Rochester, MN 55905, USA
    Neurosurgery 68:325-33; discussion 333. 2011
  6. doi request reprint A new technique for intraoperative reduction of occipitocervical instability
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Neurosurgery 66:319-23; discussion 323-4. 2010
  7. ncbi request reprint Lysis of intracerebral hematoma with stereotactically implanted tissue plasminogen activator polymers in a rabbit model
    Quoc Anh Thai
    Division of Cerebrovascular Neurosurgery, Department of Neurosurgery, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Neurosurg 105:424-9. 2006
  8. doi request reprint Adjacent-level range of motion and intradiscal pressure after posterior cervical decompression and fixation: an in vitro human cadaveric model
    Ryan M Kretzer
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Spine (Phila Pa 1976) 37:E778-85. 2012
  9. doi request reprint Stereotactic radiosurgery for spine tumors: review of current literature
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Stereotact Funct Neurosurg 88:315-21. 2010
  10. doi request reprint Intramedullary spinal cord tumor surgery: can we do it without intraoperative neurophysiological monitoring?
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Childs Nerv Syst 26:241-5. 2010

Collaborators

Detail Information

Publications31

  1. doi request reprint Role of cancer stem cells in spine tumors: review of current literature
    Wesley Hsu
    Department of Neurosurgery, Wake Forest Baptist Medical Center, Winston Salem, NC 27157 1029, USA
    Neurosurgery 71:117-25. 2012
    ..This discussion is followed by a review of what is known about the role of CSCs in the most common primary tumors of the osseous spine...
  2. doi request reprint Animal model of intramedullary spinal cord glioma using human glioblastoma multiforme neurospheres
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Neurosurg Spine 16:315-9. 2012
    ..In this study, the authors' goal was to develop a novel spinal cord tumor model using a human neurosphere cell line...
  3. doi request reprint Strategies to avoid wrong-site surgery during spinal procedures
    Wesley Hsu
    Department of Neurosurgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina 27157 1029, USA
    Neurosurg Focus 31:E5. 2011
    ..The following review discusses important issues that can help prevent WSS during spinal procedures...
  4. doi request reprint Image-guided, endoscopic, transcervical resection of cervical chordoma
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 12:431-5. 2010
    ....
  5. ncbi request reprint Three-level en bloc spondylectomy for chordoma
    Michelle J Clarke
    Department of Neurosurgery, Mayo Clinic, Rochester, MN 55905, USA
    Neurosurgery 68:325-33; discussion 333. 2011
    ..However, these procedures often are complex and require the surgeon to plan a procedure that results in negative tumor margins, protects vital neurovascular structures, and concludes with a viable biomechanical reconstruction...
  6. doi request reprint A new technique for intraoperative reduction of occipitocervical instability
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Neurosurgery 66:319-23; discussion 323-4. 2010
    ..Anterior decompression by means of a transoral or transcervical approach followed by posterior instrumentation commonly is used to treat this pathology...
  7. ncbi request reprint Lysis of intracerebral hematoma with stereotactically implanted tissue plasminogen activator polymers in a rabbit model
    Quoc Anh Thai
    Division of Cerebrovascular Neurosurgery, Department of Neurosurgery, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Neurosurg 105:424-9. 2006
    ..The authors report the use of stereotactically implanted polymers loaded with tissue plasminogen activator (tPA) to induce lysis of ICH in a rabbit model...
  8. doi request reprint Adjacent-level range of motion and intradiscal pressure after posterior cervical decompression and fixation: an in vitro human cadaveric model
    Ryan M Kretzer
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Spine (Phila Pa 1976) 37:E778-85. 2012
    ..This in vitro human cadaveric study measured adjacent-level kinematics after posterior cervical decompression and fixation...
  9. doi request reprint Stereotactic radiosurgery for spine tumors: review of current literature
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Stereotact Funct Neurosurg 88:315-21. 2010
    ..The purpose of this review is to summarize the pertinent literature regarding the use of SR for lesions of the spine and spinal cord. Particular emphasis will be placed on large clinical series of both primary and secondary spine tumors...
  10. doi request reprint Intramedullary spinal cord tumor surgery: can we do it without intraoperative neurophysiological monitoring?
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Childs Nerv Syst 26:241-5. 2010
    ..The objective of this review is to discuss the utilization of intraoperative neurophysiological monitoring (IONM) during spinal cord tumor surgery...
  11. doi request reprint Postoperative anticoagulation in patients with mechanical heart valves following surgical treatment of subdural hematomas
    Anubhav G Amin
    Department of Neurosurgery, Johns Hopkins Medical Institutions, The Johns Hopkins University School of Medicine, Meyer Bldg 8 161, 600 N Wolfe St, Baltimore, MD 21287, USA
    Neurocrit Care 19:90-4. 2013
    ..Management guidelines regarding the timing for resuming anticoagulation therapy following a surgically treated subdural hematoma (SDH) in patients with mechanical valves remains to be determined...
  12. doi request reprint Multidisciplinary management of primary tumors of the vertebral column
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Curr Treat Options Oncol 10:107-25. 2009
    ..This review will discuss the most common primary bone tumors and focus on recent surgical, medical, and radiation treatment advances...
  13. doi request reprint Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target
    Wesley Hsu
    Department of Neurosurgery and Oncology, Brain Tumor Stem Cell Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    J Neurosurg 115:760-9. 2011
    ..Thus, the objective of this study was to establish the first fully characterized primary chordoma cell line expressing gain of the T gene locus that readily recapitulates the original parental tumor phenotype in vitro and in vivo...
  14. doi request reprint Surgical considerations of spinal ependymomas in the pediatric population
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Meyer Bldg 8 161, 600 N Wolfe St, Baltimore, MD 21287, USA
    Childs Nerv Syst 25:1253-9. 2009
    ..Spinal ependymoma is the second most common spinal cord tumor in children. The clinical evaluation of these patients, operative techniques, postoperative management considerations, and long-term outcomes are discussed...
  15. ncbi request reprint Dural prostate adenocarcinoma metastasis with subdural hematoma mimicking the appearance of an epidural hematoma
    Michael J Dorsi
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, United States
    Clin Neurol Neurosurg 112:501-4. 2010
    ..Here we describe the clinical presentation, evaluation and surgical intervention of a patient with a dural prostate carcinoma metastasis with chronic subdural hematoma mimicking an epidural hematoma...
  16. doi request reprint Transoral approaches to the cervical spine
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Neurosurgery 66:119-25. 2010
    ..Endoscopic endonasal and endoscopic transcervical approaches are promising alternatives that may become more mainstream as experience with these approaches increases...
  17. doi request reprint Pediatric spinal tumors
    Wesley Hsu
    Wake Forest Baptist Hospital, Department of Neurosurgery, Winston Salem, North Carolina, USA Electronic address
    Handb Clin Neurol 112:959-65. 2013
    ..Treatment is based on tumor type, but surgical resection is the mainstay. Predictors of outcome include the histological grading, extent of resection, and neurological status at the time of surgery...
  18. doi request reprint The subdural evacuation port system: outcomes from a single institution experience and predictors of success
    Matthew T Neal
    Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, NC, 27157, United States
    Clin Neurol Neurosurg 115:658-64. 2013
    ..This report examines the largest single institution experience with the SEPS and explores patient and imaging characteristics associated with successful procedures...
  19. doi request reprint Intraoperative localization of thoracic spine level with preoperative percutaneous placement of intravertebral polymethylmethacrylate
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Spinal Disord Tech 21:72-5. 2008
    ..To evaluate the safety and utility of preoperative vertebroplasty for intraoperative localization of thoracic spinal levels...
  20. doi request reprint Delivery of stereotactic radiosurgery: a cross-platform comparison
    Trang Nguyen
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Neurol Res 33:787-91. 2011
    ..The objective of this review is to compare and contrast the various currently available stereotactic radiosurgery platforms...
  21. ncbi request reprint The FGFR/MEK/ERK/brachyury pathway is critical for chordoma cell growth and survival
    Yunping Hu
    Department of Neurosurgery and Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 and Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21201, USA
    Carcinogenesis 35:1491-9. 2014
    ..Those findings highlight that FGFR/MEK/ERK/brachyury pathway coordinately regulates chordoma cell growth and survival and may represent a novel chemotherapeutic target for chordoma. ..
  22. doi request reprint Novel placement of cortical bone trajectory screws in previously instrumented pedicles for adjacent-segment lumbar disease using CT image-guided navigation
    Analiz Rodriguez
    Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, North Carolina
    Neurosurg Focus 36:E9. 2014
    ..This unique technique results in the placement of 2 screws in the same pedicle (1 traditional pedicle trajectory and 1 CBT) and obviates the need to remove preexisting instrumentation...
  23. ncbi request reprint Delayed intracranial delivery of a nitric oxide donor from a controlled-release polymer prevents experimental cerebral vasospasm in rabbits
    Gustavo Pradilla
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Neurosurgery 55:1393-9; discussion 1399-1400. 2004
    ..We evaluated the efficacy of controlled-release polymers that contain the NO donor diethylenetriamine (DETA-NO) for the delayed treatment of vasospasm in a rabbit model of SAH...
  24. ncbi request reprint Epidural abscesses of the CNS
    Gustavo Pradilla
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lancet Neurol 8:292-300. 2009
    ..Increased clinical awareness can greatly improve outcomes by helping to diagnose patients earlier...
  25. doi request reprint Pretruncal nonaneurysmal subarachnoid hemorrhage causing basilar artery vasospasm
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, Meyer Bldg 8 161, 600 N Wolfe St, Baltimore, MD 21287, USA
    Neurocrit Care 13:256-60. 2010
    ..Although vasospasm is a common occurrence after aneurysmal subarachnoid hemorrhage and can lead to significant morbidity and mortality, vasospasm in the setting of PNSAH is rare...
  26. doi request reprint Clear-cell chondrosarcoma of the lumbar spine: case report and review of the literature
    Wesley Hsu
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Neurosurgery 68:E1160-4; discussion 1164. 2011
    ..Clear-cell chondrosarcoma is a rare subtype of chondrosarcoma. These osseous tumors are most commonly found in the end of long bones. We report a rare case of clear-cell chondrosarcoma of the osseous spine...
  27. doi request reprint Keyhole to the brain: Walter Dandy and neuroendoscopy
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Neurosurg Pediatr 3:439-42. 2009
    ..This paper reviews his contributions to the early evolution of this growing and important field of neurosurgery...
  28. ncbi request reprint Epidemiology of brachial plexus injury in the pediatric multitrauma population in the United States
    Michael J Dorsi
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Neurosurg Pediatr 5:573-7. 2010
    ..The aim of this study was to estimate the prevalence of brachial plexus injury (BPI) in pediatric multitrauma patients...
  29. doi request reprint Accuracy of percutaneous placement of a ventriculoatrial shunt under ultrasonography guidance: a retrospective study at a single institution
    Philippe Metellus
    Departments of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Neurosurg 110:867-70. 2009
    ..The authors therefore conclude that percutaneous placement of a VA shunt under preoperative radiographic guidance and ultrasonographic monitoring is a safe, effective, and reliable technique that is simple to learn...
  30. doi request reprint Frameless stereotaxy-assisted clipping of distal anterior cerebral artery aneurysm: technical note and case series
    Wesley Hsu
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Comput Aided Surg 13:41-6. 2008
    ..We report a case series of five patients in which frameless stereotaxy and CT angiographic data sets were used to minimize the extent of surgery required to clip distal ACA aneurysms...
  31. ncbi request reprint Local delivery of interleukin-2 and adriamycin is synergistic in the treatment of experimental malignant glioma
    Wesley Hsu
    Departments of Neurosurgery and Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Neurooncol 74:135-40. 2005
    ..In the current study, we hypothesized that local delivery of ADR and IL-2 might act synergistically against experimental intracranial glioma...