Po Shiuan Hsieh

Summary

Publications

  1. ncbi request reprint Functional interaction of AT1 and AT2 receptors in fructose-induced insulin resistance and hypertension in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan 114
    Metabolism 54:157-64. 2005
  2. doi request reprint Inflammatory change of fatty liver induced by intraportal low-dose lipopolysaccharide infusion deteriorates pancreatic insulin secretion in fructose-induced insulin-resistant rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
    Liver Int 28:1167-75. 2008
  3. doi request reprint Mild portal endotoxaemia induces subacute hepatic inflammation and pancreatic beta-cell dysfunction in rats
    P S Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
    Eur J Clin Invest 38:640-8. 2008
  4. doi request reprint COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
    Obesity (Silver Spring) 17:1150-7. 2009
  5. ncbi request reprint Diminution of hypertriglyceridemia-induced pressor effect under hyperinsulinemic condition in normal and fructose-induced insulin resistant rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, ROC
    Chin J Physiol 50:99-104. 2007
  6. doi request reprint Selective COX2 inhibition improves whole body and muscular insulin resistance in fructose-fed rats
    P S Hsieh
    Department of Physiology and Biophysics, National Defence Medical Centre, Taipei, Taiwan
    Eur J Clin Invest 38:812-9. 2008
  7. doi request reprint Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats
    P S Hsieh
    National Defense Medical Center, Taipei, Taiwan
    Eur J Clin Invest 40:164-71. 2010
  8. ncbi request reprint Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan
    J Hypertens 23:2209-17. 2005
  9. ncbi request reprint Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan, Republic of China
    Am J Hypertens 17:707-711. 2004
  10. ncbi request reprint Aqueous extract of Monascus purpureus M9011 prevents and reverses fructose-induced hypertension in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan, Republic of China
    J Agric Food Chem 51:3945-50. 2003

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Functional interaction of AT1 and AT2 receptors in fructose-induced insulin resistance and hypertension in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan 114
    Metabolism 54:157-64. 2005
    ..Furthermore, AT1R- and AT2R-mediated effects on blood pressure are disassociated with their actions on glucose metabolism in this hypertensive model...
  2. doi request reprint Inflammatory change of fatty liver induced by intraportal low-dose lipopolysaccharide infusion deteriorates pancreatic insulin secretion in fructose-induced insulin-resistant rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
    Liver Int 28:1167-75. 2008
    ..This study tested whether subacute inflammatory change of fatty liver induced by portal endotoxaemia is detrimental to pancreatic insulin secretion in fructose-fed rats (FFRs) with fatty liver...
  3. doi request reprint Mild portal endotoxaemia induces subacute hepatic inflammation and pancreatic beta-cell dysfunction in rats
    P S Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
    Eur J Clin Invest 38:640-8. 2008
    ..This study tests whether portal endotoxaemia is a pathogenic link between chronic subacute hepatic inflammation and pancreatic beta-cell dysfunction...
  4. doi request reprint COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan
    Obesity (Silver Spring) 17:1150-7. 2009
    ..Our findings suggest that COX-2 activation in fat inflammation is important in the development of insulin resistance and fatty liver in high fat induced obese rats...
  5. ncbi request reprint Diminution of hypertriglyceridemia-induced pressor effect under hyperinsulinemic condition in normal and fructose-induced insulin resistant rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, ROC
    Chin J Physiol 50:99-104. 2007
    ..The present results demonstrated that hypertriglyceridemia-induced pressor response was diminished under hyperinsulinemic condition in both normal and fructose-induced insulin resistant rats...
  6. doi request reprint Selective COX2 inhibition improves whole body and muscular insulin resistance in fructose-fed rats
    P S Hsieh
    Department of Physiology and Biophysics, National Defence Medical Centre, Taipei, Taiwan
    Eur J Clin Invest 38:812-9. 2008
    ..Aims of this study were to examine the effects of COX1 and COX2 inhibitors on whole body and muscular insulin resistance in fructose-fed rats, an animal model of the metabolic syndrome...
  7. doi request reprint Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats
    P S Hsieh
    National Defense Medical Center, Taipei, Taiwan
    Eur J Clin Invest 40:164-71. 2010
    ..The aim was to examine whether the inhibition of selective cyclooxygenase (COX) 2 activation could suppress the development of inflammatory reaction in visceral and subcutaneous abdominal fats of high-fat-induced obese rats...
  8. ncbi request reprint Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan
    J Hypertens 23:2209-17. 2005
    ..To examine whether angiotensin II type 2 receptors (AT2R) are involved in the reversal of fructose-induced hypertension and insulin resistance after chronic angiotensin II type 1 receptor (AT1R) blockade...
  9. ncbi request reprint Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan, Republic of China
    Am J Hypertens 17:707-711. 2004
    ....
  10. ncbi request reprint Aqueous extract of Monascus purpureus M9011 prevents and reverses fructose-induced hypertension in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan, Republic of China
    J Agric Food Chem 51:3945-50. 2003
    ....
  11. ncbi request reprint Importance of cyclooxygenase 2-mediated low-grade inflammation in the development of fructose-induced insulin resistance in rats
    Tse Tsung Liu
    Department of Family and Community, Hualien Army Force Hospital, Hualien, Taiwan, Republic of China
    Chin J Physiol 52:65-71. 2009
    ..The present study demonstrates that the COX2-mediated low-grade inflammation, especially mediated by increase in oxidative stress was important in the development of insulin resistance in fructose-fed rats...
  12. ncbi request reprint Augmentation of nitric oxide is crucial for the time-dependent effects of rosiglitazone on blood pressure and baroreflex function in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei
    J Hypertens 26:83-92. 2008
    ..To determine the time-dependent effects of rosiglitazone (RSG) on blood pressure (MAP) and baroreflex sensitivity (BRS) and the involvement of nitric oxide (NO) in these effects...
  13. doi request reprint Discipline-specific insulin sensitivity in athletes
    Yi Liang Chen
    Laboratory of Exercise Biochemistry, Taipei Physical Education College, Taipei, Taiwan
    Nutrition 25:1137-42. 2009
    ..The main goal of the study was to compare insulin sensitivity in athletes (n=757) and physically active controls (n=670) in relation to the two factors...
  14. doi request reprint Circulating growth arrest-specific 6 protein is associated with adiposity, systemic inflammation, and insulin resistance among overweight and obese adolescents
    Fone Ching Hsiao
    MD, Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri Service General Hospital, National Defense Medical Center, No 325, Section 2, Chenggong Road, Neihu District, Taipei City 114, Taiwan
    J Clin Endocrinol Metab 98:E267-74. 2013
    ..The potential role of the Gas6/TAM system in the initiation of childhood obesity and obesity-associated complications deserves further attention...
  15. doi request reprint Alleviation of hyperglycemia in diabetic rats by intraportal injection of insulin-producing cells generated from surgically resected human pancreatic tissue
    Jia Fwu Shyu
    Department of Biology and Anatomy, National Defense Medical Center, Taipei 11490, Taiwan, ROC
    J Endocrinol 208:233-44. 2011
    ..Thus, surgically resected pancreatic tissue may represent an alternative source of functional insulin-producing cells...
  16. pmc Activation of estrogen receptor is crucial for resveratrol-stimulating muscular glucose uptake via both insulin-dependent and -independent pathways
    Jen Ying Deng
    Department of Life Science and Center for Healthy and Aging Research, College of Medicine, Chang Gung University, Tao Yuan, Taiwan
    Diabetes 57:1814-23. 2008
    ..However, it remains unknown whether activation of ER is involved in the metabolic effects of RSV via insulin-dependent and -independent mechanisms...
  17. ncbi request reprint Attenuation of hypertriglyceridemia-induced pressor effect in rats with fructose-induced insulin resistance
    Hung Jung Lin
    Department of Emergency Medicine, Chi Mei Medical Center, Tainan, ROC
    Chin J Physiol 50:16-21. 2007
    ..The present results suggest that the prolonged pressor response induced by acute hypertriglyceridemia is attenuated in rats with fructose-induced insulin resistance...
  18. ncbi request reprint Hyperinsulinemia instead of insulin resistance induces baroreflex dysfunction in chronic insulin-infused rats
    Ling Zong Hong
    Department of Education and Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan
    Am J Hypertens 20:451-8. 2007
    ..The present study was undertaken to compare the effects of chronic hyperinsulinemia with or without insulin resistance on the autonomic control of heart rate (HR) in rats...
  19. ncbi request reprint Effect of hepatic denervation on peripheral insulin sensitivity in conscious dogs
    Mary Courtney Moore
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Am J Physiol Endocrinol Metab 282:E286-96. 2002
    ..05 vs. Sham-Sal), 9.8 +/- 0.9 (P < 0.05 vs. Sham-Sal), and 13.6 +/- 1.8 mg. kg(-1) x min(-1), respectively. DN caused peripheral insulin resistance, and intraportal but not peripheral acetylcholine restored insulin sensitivity...