Thomas J Howard

Summary

Publications

  1. doi The role of antimicrobial therapy in severe acute pancreatitis
    Thomas J Howard
    Hepatobiliary Surgical Cancer Care, Community Hospital North, 8040 Clearvista Parkway, Suite 240, Indianapolis, IN 46256, USA
    Surg Clin North Am 93:585-93. 2013
  2. ncbi CT vs MRCP: optimal classification of IPMN type and extent
    Joshua A Waters
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Gastrointest Surg 12:101-9. 2008
  3. pmc Small pancreatic and periampullary neuroendocrine tumors: resect or enucleate?
    Susan C Pitt
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202 5124, USA
    J Gastrointest Surg 13:1692-8. 2009
  4. ncbi A margin-negative R0 resection accomplished with minimal postoperative complications is the surgeon's contribution to long-term survival in pancreatic cancer
    Thomas J Howard
    Pancreas Research Group, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Gastrointest Surg 10:1338-45; discussion 1345-6. 2006
  5. ncbi Intraductal papillary mucinous neoplasms: predictors of malignant and invasive pathology
    C Max Schmidt
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Ann Surg 246:644-51; discussion 651-4. 2007
  6. ncbi Pancreatic cystic neuroendocrine tumors: preoperative diagnosis with endoscopic ultrasound and fine-needle immunocytology
    Marshall S Baker
    Department of Surgery, Indiana University School of Medicine, IU Medical Center Cancer Pavilion RT 130D, 535 Barnhill Drive, Indianapolis, IN 46202, USA
    J Gastrointest Surg 12:450-6. 2008
  7. pmc Post-operative morbidity results in decreased long-term survival after resection for hilar cholangiocarcinoma
    Aakash Chauhan
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    HPB (Oxford) 13:139-47. 2011
  8. doi Mechanisms of primary operative failure and results of remedial operation in patients with chronic pancreatitis
    Thomas J Howard
    Department of Surgery and Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA
    J Gastrointest Surg 12:2087-95; discussion 2095-6. 2008
  9. ncbi Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience
    C Max Schmidt
    Department of Surgery, Indiana University School of Medicine, 980 W Walnut Street, Indianapolis, IN 46202, USA
    Arch Surg 145:634-40. 2010
  10. ncbi Total pancreatectomy (R0 resection) improves survival over subtotal pancreatectomy in isolated neck margin positive pancreatic adenocarcinoma
    C Max Schmidt
    Department of Surgery and Indiana University Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Surgery 142:572-8; discussion 578-80. 2007

Collaborators

Detail Information

Publications45

  1. doi The role of antimicrobial therapy in severe acute pancreatitis
    Thomas J Howard
    Hepatobiliary Surgical Cancer Care, Community Hospital North, 8040 Clearvista Parkway, Suite 240, Indianapolis, IN 46256, USA
    Surg Clin North Am 93:585-93. 2013
    ..Positive cultures should guide antimicrobial therapy, and for infected pancreatic necrosis, antibiotics should be used in conjunction with interventional techniques for source control...
  2. ncbi CT vs MRCP: optimal classification of IPMN type and extent
    Joshua A Waters
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Gastrointest Surg 12:101-9. 2008
    ..CT scanning commonly serves as the primary imaging modality before surgery. We hypothesized MRCP provides better characterization of IPMN type/extent, which more closely matches actual pathology...
  3. pmc Small pancreatic and periampullary neuroendocrine tumors: resect or enucleate?
    Susan C Pitt
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202 5124, USA
    J Gastrointest Surg 13:1692-8. 2009
    ..The aim of this study was to compare the outcomes of enucleation versus resection in patients with small pancreatic, ampullary, and duodenal neuroendocrine tumors (NETs)...
  4. ncbi A margin-negative R0 resection accomplished with minimal postoperative complications is the surgeon's contribution to long-term survival in pancreatic cancer
    Thomas J Howard
    Pancreas Research Group, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Gastrointest Surg 10:1338-45; discussion 1345-6. 2006
    ..Long-term survival in patients with pancreatic cancer after resection remains poor. Achieving a margin negative resection (R0) with no postoperative complications are prognostic variables that can be affected by the surgeon...
  5. ncbi Intraductal papillary mucinous neoplasms: predictors of malignant and invasive pathology
    C Max Schmidt
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Ann Surg 246:644-51; discussion 651-4. 2007
    ..Determine whether size and other preoperative parameters predict malignant or invasive intraductal papillary mucinous neoplasia (IPMN)...
  6. ncbi Pancreatic cystic neuroendocrine tumors: preoperative diagnosis with endoscopic ultrasound and fine-needle immunocytology
    Marshall S Baker
    Department of Surgery, Indiana University School of Medicine, IU Medical Center Cancer Pavilion RT 130D, 535 Barnhill Drive, Indianapolis, IN 46202, USA
    J Gastrointest Surg 12:450-6. 2008
    ..This report represents the largest series of CNETs treated to date, documents the role of EUS in preoperative diagnosis, and describes current management...
  7. pmc Post-operative morbidity results in decreased long-term survival after resection for hilar cholangiocarcinoma
    Aakash Chauhan
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    HPB (Oxford) 13:139-47. 2011
    ..The purpose of the present study was to demonstrate that post-operative morbidity (PM) associated with resections of hilar cholangiocarcinoma (HCCA) is associated with short- and long-term patient survival...
  8. doi Mechanisms of primary operative failure and results of remedial operation in patients with chronic pancreatitis
    Thomas J Howard
    Department of Surgery and Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA
    J Gastrointest Surg 12:2087-95; discussion 2095-6. 2008
    ..Resection and drainage operations achieve long-term pain relief in approximately 85% of patients with chronic pancreatitis (CP). In patients who develop recurrent pain, a few data exist on the long-term results of remedial operations...
  9. ncbi Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience
    C Max Schmidt
    Department of Surgery, Indiana University School of Medicine, 980 W Walnut Street, Indianapolis, IN 46202, USA
    Arch Surg 145:634-40. 2010
    ..To determine the importance of hospital volume, surgeon experience, and surgeon volume in performing pancreaticoduodenectomy (PD)...
  10. ncbi Total pancreatectomy (R0 resection) improves survival over subtotal pancreatectomy in isolated neck margin positive pancreatic adenocarcinoma
    C Max Schmidt
    Department of Surgery and Indiana University Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Surgery 142:572-8; discussion 578-80. 2007
    ..In patients undergoing pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PC), conversion to total pancreatectomy (TP) may be necessary to achieve R0 resection...
  11. doi Pancreatic necrosectomy: North American mortality is much lower than expected
    Purvi Y Parikh
    Department of Surgery, Indiana University, Indianapolis, IN, USA
    J Am Coll Surg 209:712-9. 2009
    ..But no national data have been available for patients with necrotizing pancreatitis. In 2007, a CPT code specific for debridement of pancreatic necrosis became available...
  12. ncbi PGE(2) in pancreatic cyst fluid helps differentiate IPMN from MCN and predict IPMN dysplasia
    C Max Schmidt
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    J Gastrointest Surg 12:243-9. 2008
    ..PGE(2) level may also be an indicator of malignant progression of IPMN before ductal obstruction by tumor. Prospective evaluation will be necessary to evaluate the clinical role of PGE(2) level in pancreatic fluid...
  13. ncbi Pancreatic disorders in children: relationship of postoperative morbidity and the indication for surgery
    Aaron Rabinovich
    Indiana University School of Medicine and Riley Children s Hospital, Indianapolis, Indiana 46202 5125, USA
    Am Surg 72:641-3. 2006
    ..Pancreatic surgery in children is associated with a very low mortality (1.6%) and morbidity equal to that of adult patients. Unique types of morbidities occur with each category of disease state...
  14. ncbi Fatty pancreas: a factor in postoperative pancreatic fistula
    Abhishek Mathur
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Ann Surg 246:1058-64. 2007
    ..To determine whether patients who develop a pancreatic fistula after pancreatoduodenectomy are more likely to have pancreatic fat than matched controls...
  15. doi A prospective, randomized study of EUS-guided celiac plexus neurolysis for pancreatic cancer: one injection or two?
    Julia K LeBlanc
    Division of Gastroenterology and Hepatology, Indiana University Medical Center IU Health, Indianapolis, Indiana, USA
    Gastrointest Endosc 74:1300-7. 2011
    ..The technique of alcohol injection during EUS-guided celiac plexus neurolysis (CPN) in patients with pancreatic cancer-related pain has not been standardized...
  16. doi Splenic preserving distal pancreatectomy: does vessel preservation matter?
    Joal D Beane
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Am Coll Surg 212:651-7; discussion 657-8. 2011
    ..However, no data are available on the relative merits of these techniques. The aim of this analysis was to compare the outcomes of splenic preserving distal pancreatectomy with and without splenic vessel preservation...
  17. doi Pancreatic surgery: evolution at a high-volume center
    Kathryn M Ziegler
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Surgery 148:702-9; discussion 709-10. 2010
    ..Therefore, the aims of this report are to determine whether the pancreatic operations or the spectrum of disease have evolved at a high-volume center...
  18. doi Clinical framework to guide operative decision making in disconnected left pancreatic remnant (DLPR) following acute or chronic pancreatitis
    Kariuki P Murage
    Departments of Surgery and Radiology, Indiana University School of Medicine, Indianapolis, IN, USA
    Surgery 148:847-56; discussion 856-7. 2010
    ..Optimal operative treatment, either distal pancreatectomy (DP) or internal drainage (ID), remains unknown. This paper critically evaluates our operative experience in patients with DLPR...
  19. ncbi Small-bowel complications of major gastrointestinal tract surgery
    Kumaresan Sandrasegaran
    Department of Radiology, Indiana University Medical Center, Indianapolis, IN 46202, USA
    AJR Am J Roentgenol 185:671-81. 2005
    ..Gastrointestinal complications of major abdominal surgery often require radiologic assessment. The purpose of this article is to review the expected imaging findings and complications after commonly performed gastric and pancreatic surgery...
  20. ncbi Disconnection of the pancreatic duct: an important but overlooked complication of severe acute pancreatitis
    Kumaresan Sandrasegaran
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Radiographics 27:1389-400. 2007
    ..Early recognition of disconnected pancreatic duct obviates unnecessary and potentially harmful drainage procedures...
  21. ncbi Improved outcomes in postoperative and pancreatitis-related visceral pseudoaneurysms
    Nicholas J Zyromski
    Department of Surgery, Indiana University, Indianapolis, IN 46202, USA
    J Gastrointest Surg 11:50-5. 2007
    ..Early recognition and prompt angiographic occlusion leads to improved outcomes...
  22. doi Small-bowel obstruction: state-of-the-art imaging and its role in clinical management
    Dean D T Maglinte
    Department of Radiology, Indiana University Medical Center, Indianapolis, Indiana 46202 5253, USA
    Clin Gastroenterol Hepatol 6:130-9. 2008
    ..This review focuses on modern imaging techniques and their role in both the diagnosis and treatment of patients with SBO...
  23. ncbi Pyogenic liver abscess following pancreaticoduodenectomy: risk factors, treatment, and long-term outcome
    Victor C Njoku
    Department of Surgery and Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA
    J Gastrointest Surg 18:922-8. 2014
    ..Pyogenic liver abscess (PLA) is an uncommon complication following PD with little information on its incidence or treatment. This study was done to examine the incidence, risk factors, treatment, and long-term outcome of PLA after PD...
  24. pmc Natural history of pancreatitis-induced splenic vein thrombosis: a systematic review and meta-analysis of its incidence and rate of gastrointestinal bleeding
    James R Butler
    Department of Surgery, Indiana University School of Medicine, Indianapolis, 46202, USA
    HPB (Oxford) 13:839-45. 2011
    ..Despite this influence, its incidence and the rate of associated gastrointestinal (GI) bleeding are imprecisely known...
  25. doi Acute superior mesenteric-portal vein thrombosis after pancreaticoduodenectomy: treatment by operative thrombectomy
    Nicholas J Zyromski
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Ind 46202, USA
    Surgery 143:566-7. 2008
  26. ncbi Surgery for chronic pancreatitis: cross-sectional imaging of postoperative anatomy and complications
    Kumaresan Sandrasegaran
    Department of Radiology, Indiana University Medical Center, 550 N University Blvd, UH 0279, Indianapolis, IN 46202, USA
    AJR Am J Roentgenol 184:1118-27. 2005
    ..Surgery is increasingly undertaken for intractable chronic pancreatitis. We evaluated the postsurgical anatomy and complications of surgical options including Whipple, Puestow, Frey's, and Beger's procedures...
  27. ncbi CT of acute biliopancreatic limb obstruction
    Kumaresan Sandrasegaran
    Department of Radiology, Indiana University School of Medicine, UH 0279, 550 N University Blvd, Indianapolis, IN 46202, USA
    AJR Am J Roentgenol 186:104-9. 2006
    ..Our objective was to report the CT features of biliopancreatic limb (afferent loop) obstruction...
  28. ncbi Influence of bactibilia after preoperative biliary stenting on postoperative infectious complications
    Thomas J Howard
    Department of Surgery, Indiana University School of Medicine, Indianapolis, USA
    J Gastrointest Surg 10:523-31. 2006
    ..Jaundiced patients can undergo preoperative biliary stenting while maintaining an acceptable postoperative morbidity rate...
  29. ncbi Can pancreaticoduodenectomy be used to palliate selective metastatic malignancies? Case report of malignant fibrous histiocytoma
    Mindy M Ho
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Gastrointest Surg 9:934-7. 2005
  30. ncbi New concepts in staging and treatment of locally advanced pancreatic head cancer
    Chandana G Lall
    Department of Radiology, Indiana University Medical Center, UH 0279, 550 N University Blvd, Indianapolis, IN 46202, USA
    AJR Am J Roentgenol 189:1044-50. 2007
    ..As a result, the imaging criteria to determine which patients are candidates for potentially curative resection are evolving...
  31. doi Radiation dose from computed tomography in patients with necrotizing pancreatitis: how much is too much?
    Chad G Ball
    Department of Surgery, Indiana University, 545 Barnhill Drive, Emerson Hall 203, Indianapolis, IN 46202, USA
    J Gastrointest Surg 14:1529-35. 2010
    ..Computed tomography (CT) is the gold standard for defining pancreatic necrosis. The primary goal was to identify the frequency and effective radiation dose of CT imaging for patients with necrotizing pancreatitis...
  32. doi Annular pancreas: dramatic differences between children and adults
    Nicholas J Zyromski
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Am Coll Surg 206:1019-25; discussion 1025-7. 2008
    ..In addition, no large analysis has compared children and adults. Recently, prenatal diagnosis and advances in imaging have led to increased experience with this condition...
  33. ncbi Declining morbidity and mortality rates in the surgical management of pancreatic necrosis
    Thomas J Howard
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Gastrointest Surg 11:43-9. 2007
    ..04) were significantly less in group II patients. Current methods of surgical management utilizing IAP guidelines have resulted in a decreased operative morbidity, mortality, and hospital length of stay in patients with PN...
  34. doi The burden of incisional hernia in necrotizing pancreatitis: how can we improve?
    Hayder H Al-Azzawi
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg 199:310-4; discussion 314. 2010
    ..However, no published data exist regarding the incidence of IH in NP. The aim of the current study was to define the incidence of and identify risk factors for developing IH after pancreatic debridement...
  35. ncbi Pancreatic mucinous adenocarcinoma with peritoneal metastases
    Wee Chian Lim
    Department of Medicine, Division of Gastroenterology and Hepatology, Indiana University Medical Center, Indianapolis, Indiana, USA
    Gastrointest Endosc 62:140-1. 2005
  36. ncbi Frequency of biliary complications after laparoscopic cholecystectomy detected by ERCP: experience at a large tertiary referral center
    Mubashir H Khan
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Gastrointest Endosc 65:247-52. 2007
    ..Although a learning curve phenomenon was attributed to biliary injuries early after its introduction, we were interested in trends in biliary injury rates over time as laparoscopic cholecystectomy has become a mature technology...
  37. doi A phase II study of gemcitabine in combination with radiation therapy in patients with localized, unresectable, pancreatic cancer: a Hoosier Oncology Group study
    Higinia R Cardenes
    Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, USA
    Am J Clin Oncol 34:460-5. 2011
    ..A Phase II study was conducted at Indiana University to evaluate the safety and efficacy of combined weekly Gemcitabine (GEM) with external beam radiotherapy (RT) in unresectable, locally advanced pancreatic cancer (LAPC)...
  38. ncbi Pancreaticoduodenectomy: a 20-year experience in 516 patients
    C Max Schmidt
    Department of Surgery, University Hospital, Indiana University School of Medicine, Indianapolis, USA
    Arch Surg 139:718-25; discussion 725-7. 2004
    ..Pancreaticoduodenectomy (PD) is a safe procedure for a variety of periampullary conditions...
  39. ncbi Quality of life after bilateral thoracoscopic splanchnicectomy: long-term evaluation in patients with chronic pancreatitis
    Thomas J Howard
    Department of Surgery, Indiana University School of Medicine, Emerson Hall 523, 545 Barnhill Drive, Indianapolis, IN 46202, USA
    J Gastrointest Surg 6:845-52; discussion 853-4. 2002
    ..Bilateral thoracoscopic splanchnicectomy appears to work best in patients who have had no prior operative or endoscopic interventions...
  40. ncbi Disconnected pancreatic duct syndrome: imaging findings and therapeutic implications in 26 surgically corrected patients
    Mark Tann
    Department of Radiology, Indiana University School of Medicine, 550 N University Boulevard, RM0279, Indianapolis, IN 46202 5253, USA
    J Comput Assist Tomogr 27:577-82. 2003
    ..The purpose of our study is to describe accurately the imaging features of CT scanning and endoscopic retrograde pancreatography (ERCP) that define the DPDS...
  41. ncbi Spontaneous duodenal hematoma: a rare cause of upper gastrointestinal tract obstruction
    Brent R Weil
    Department of Surgery, Indiana University School of Medicine, Indianapolis, USA
    Arch Surg 143:794-6. 2008
    ..Here we report a case of a 75-year-old man who spontaneously developed an intramural duodenal hematoma with no apparent inciting event or risk factors...
  42. ncbi Use of a new sealing device to simplify jejunal resection during pancreaticoduodenectomy
    Thomas J Howard
    Pancreas Research Group and the Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg 190:504-6. 2005
    ....
  43. ncbi The multifaceted role of radiology in small bowel obstruction
    Kumaresan Sandrasegaran
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN 46202 5257, USA
    Semin Ultrasound CT MR 24:319-35. 2003
    ..The meaning of frequently used but poorly defined terms in describing intestinal obstruction is clarified and illustrated...
  44. ncbi Prophylactic antibiotics alter the bacteriology of infected necrosis in severe acute pancreatitis
    Thomas J Howard
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    J Am Coll Surg 195:759-67. 2002
    ....
  45. ncbi Efficacy of venous reconstruction in patients with adenocarcinoma of the pancreatic head
    Thomas J Howard
    Pancreas Research Group and the Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Gastrointest Surg 7:1089-95. 2003
    ..Kalpan-Meier life table analysis shows similar survival curves when compared to a contemporary cohort of patients who do not undergo venous reconstruction...