Michael V Holmes

Summary

Publications

  1. ncbi The role of dietary vitamin K in the management of oral vitamin K antagonists
    Michael V Holmes
    Department of Clinical Pharmacology, Guy s and St Thomas NHS Foundation Trust, London, UK
    Blood Rev 26:1-14. 2012
  2. ncbi CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis
    Michael V Holmes
    Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Pl, London, WC1E 6BT, United Kingdom
    JAMA 306:2704-14. 2011
  3. ncbi The genetics of coronary heart disease
    Daniel I Swerdlow
    Genetic Epidemiology Group, Department of Epidemiology and Public Health, UCL Institute of Epidemiology and Health Care, University College London, UK
    Br Med Bull 102:59-77. 2012
  4. ncbi Complex disease genetics: present and future translational applications
    Michael V Holmes
    Centre for Clinical Pharmacology, Division of Medicine, University College London, Rayne Institute, 5 University Street, London, WC1E 6JJ, UK
    Genome Med 1:104. 2009
  5. ncbi Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies
    Michael V Holmes
    Centre for Clinical Pharmacology, University College London, London, United Kingdom
    PLoS ONE 4:e7960. 2009
  6. ncbi Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
    Michael V Holmes
    Research Department of Epidemiology and Public Health, University College London, London, UK
    Lancet 378:584-94. 2011
  7. ncbi Utility of genetic determinants of lipids and cardiovascular events in assessing risk
    Michael V Holmes
    Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Nat Rev Cardiol 8:207-21. 2011

Detail Information

Publications7

  1. ncbi The role of dietary vitamin K in the management of oral vitamin K antagonists
    Michael V Holmes
    Department of Clinical Pharmacology, Guy s and St Thomas NHS Foundation Trust, London, UK
    Blood Rev 26:1-14. 2012
    ....
  2. ncbi CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis
    Michael V Holmes
    Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Pl, London, WC1E 6BT, United Kingdom
    JAMA 306:2704-14. 2011
    ....
  3. ncbi The genetics of coronary heart disease
    Daniel I Swerdlow
    Genetic Epidemiology Group, Department of Epidemiology and Public Health, UCL Institute of Epidemiology and Health Care, University College London, UK
    Br Med Bull 102:59-77. 2012
    ..Recent major advances in genomic science and technology have opened new avenues of investigation in the pathogenesis of CHD, some of which are leading to clinical translation...
  4. ncbi Complex disease genetics: present and future translational applications
    Michael V Holmes
    Centre for Clinical Pharmacology, Division of Medicine, University College London, Rayne Institute, 5 University Street, London, WC1E 6JJ, UK
    Genome Med 1:104. 2009
    ..ABSTRACT: A report on the British Atherosclerosis Society autumn meeting 'Genetics of Complex Diseases', Cambridge, UK, 17-18 September 2009...
  5. ncbi Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies
    Michael V Holmes
    Centre for Clinical Pharmacology, University College London, London, United Kingdom
    PLoS ONE 4:e7960. 2009
    ..Studies of the genetic basis of drug response could help clarify mechanisms of drug action/metabolism, and facilitate development of genotype-based predictive tests of efficacy or toxicity (pharmacogenetics)...
  6. ncbi Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
    Michael V Holmes
    Research Department of Epidemiology and Public Health, University College London, London, UK
    Lancet 378:584-94. 2011
    ..We aimed to reduce the effect of small-study bias and investigate whether folate status modifies the association between MTHFR 677C→T and stroke in a genetic analysis and meta-analysis of randomised controlled trials...
  7. ncbi Utility of genetic determinants of lipids and cardiovascular events in assessing risk
    Michael V Holmes
    Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Nat Rev Cardiol 8:207-21. 2011
    ..Many of the issues we discuss hold true for any late-onset common disease with modifiable risk factors and proven preventative strategies...