Research Topics

Edward C Holmes

Summary

Publications

  1. doi request reprint The evolution and emergence of hantaviruses
    Edward C Holmes
    Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China Electronic address
    Curr Opin Virol 10:27-33. 2015
  2. pmc Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus
    Jie Cui
    Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia
    Virol J 10:304. 2013
  3. pmc Extensive diversity of Rickettsiales bacteria in two species of ticks from China and the evolution of the Rickettsiales
    Yan Jun Kang
    Department of Zoonoses, State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China
    BMC Evol Biol 14:167. 2014
  4. pmc Novel non-parametric models to estimate evolutionary rates and divergence times from heterochronous sequence data
    Mathieu Fourment
    Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, Australia
    BMC Evol Biol 14:163. 2014
  5. pmc Malpais spring virus is a new species in the genus vesiculovirus
    Nikos Vasilakis
    Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Virol J 10:69. 2013
  6. pmc Identification of diverse full-length endogenous betaretroviruses in megabats and microbats
    Joshua A Hayward
    Retroviral Biology and Antivirals Laboratory, Centre for Virology, Burnet Institute, Melbourne, VIC 3004, Australia
    Retrovirology 10:35. 2013
  7. pmc What can we predict about viral evolution and emergence?
    Edward C Holmes
    Sydney Emerging Infections and Biosecurity Institute, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia
    Curr Opin Virol 3:180-4. 2013

Collaborators

  • Jie Cui
  • Mathieu Fourment
  • Yan Jun Kang
  • Joshua A Hayward
  • Lin Fa Wang
  • Nikos Vasilakis
  • Yu Jiang Guo
  • Gao Yu Zhao
  • Yong zhen Zhang
  • Xiao Ping Chen
  • Stephen J Dumler
  • Ming Hui Chen
  • Joseph J Gillespie
  • Bao Pan
  • Mang Shi
  • Xiu Nian Diao
  • Yanwen Xiong
  • Wei Ming Fu
  • Gilda Tachedjian
  • Hume Field
  • STEVEN WIDEN
  • Mary Tachedjian
  • Amelia Pa Travassos da Rosa
  • Peter J Walker
  • John Sebastian Eden
  • Thomas G Wood
  • Robert B Tesh

Detail Information

Publications7

  1. doi request reprint The evolution and emergence of hantaviruses
    Edward C Holmes
    Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China Electronic address
    Curr Opin Virol 10:27-33. 2015
    ..As a consequence, the evolution and emergence of hantaviruses is more complex than previously anticipated, and may serve as a realistic model for other viral groups. ..
  2. pmc Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus
    Jie Cui
    Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia
    Virol J 10:304. 2013
    ..MERS-CoV utilizes the dipeptidyl peptidase 4 (DPP4) host cell receptor, and analysis of the long-term interaction between virus and receptor provides key information on the evolutionary events that lead to the viral emergence...
  3. pmc Extensive diversity of Rickettsiales bacteria in two species of ticks from China and the evolution of the Rickettsiales
    Yan Jun Kang
    Department of Zoonoses, State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China
    BMC Evol Biol 14:167. 2014
    ....
  4. pmc Novel non-parametric models to estimate evolutionary rates and divergence times from heterochronous sequence data
    Mathieu Fourment
    Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, Australia
    BMC Evol Biol 14:163. 2014
    ..In the case of Bayesian inference methods the impact of the prior on branching times is not clearly understood, and if the amount of data is limited the posterior could be strongly influenced by the prior...
  5. pmc Malpais spring virus is a new species in the genus vesiculovirus
    Nikos Vasilakis
    Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Virol J 10:69. 2013
    ....
  6. pmc Identification of diverse full-length endogenous betaretroviruses in megabats and microbats
    Joshua A Hayward
    Retroviral Biology and Antivirals Laboratory, Centre for Virology, Burnet Institute, Melbourne, VIC 3004, Australia
    Retrovirology 10:35. 2013
    ..To improve our understanding of betaretroviruses in an evolutionarily distinct host species, we characterized ╬▓ERVs present in the genomes and transcriptomes of mega- and microbats, which are an important reservoir of emerging viruses...
  7. pmc What can we predict about viral evolution and emergence?
    Edward C Holmes
    Sydney Emerging Infections and Biosecurity Institute, School of Biological Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia
    Curr Opin Virol 3:180-4. 2013
    ..I also emphasize that a properly grounded research program in disease prediction must involve a synthesis of ecological and genetic perspectives...