Relationship between apolipoprotein E4 genotype and white matter integrity in HIV-positive young adults in South AfricaJacqueline Hoare
Department of Psychiatry and Mental Health, University of Cape Town, Anzio Road Observatory, Cape Town, 7925, South Africa
Eur Arch Psychiatry Clin Neurosci 263:189-95. 2013
..007). These data indicate that the ε4 allelic variant of ApoE is associated with memory impairment and white matter damage of the corpus callosum in HIV-positive subjects...
- A diffusion tensor imaging and neuropsychological study of prospective memory impairment in South African HIV positive individuals
Hoare Jacqueline
Department of Psychiatry and Mental Health, University of Cape Town, Anzio Road Observatory, 7925 Cape Town, South Africa
Metab Brain Dis 27:289-97. 2012
..0035), the corpus collosum (p = 0.006) and the cingulum (p = 0.0033) when compared to those who were HIV positive with good ProM. This study reinforces the importance of ProM assessment in HIV...
- A diffusion tensor imaging and neurocognitive study of HIV-positive children who are HAART-naïve "slow progressors"
Jacqueline Hoare
Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa
J Neurovirol 18:205-12. 2012
..These data suggest that demyelination as reflected by the increase in RD may be a prominent disease process in paediatric HIV infection...
- White matter correlates of apathy in HIV-positive subjects: a diffusion tensor imaging study
Jacqueline Hoare
Department of Psychiatry and Mental Health, University of Cape Town, Anzio Road Observatory, 7925, Cape Town, South Africa
J Neuropsychiatry Clin Neurosci 22:313-20. 2010
..Results of the study confirmed the hypothesis which anticipated changes associated with apathy in white matter tracts that relay through the medial prefrontal cortex...
- White-Matter damage in Clade C HIV-positive subjects: a diffusion tensor imaging study
Jacqueline Hoare
Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa
J Neuropsychiatry Clin Neurosci 23:308-15. 2011
..This study provides evidence that white-matter integrity is compromised in individuals infected with clade C HIV...
- Characterization of HIV-Associated Neurocognitive Disorders among individuals starting antiretroviral therapy in South Africa
John A Joska
Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa
AIDS Behav 15:1197-203. 2011
..In a regression model, a lower level of education and male gender were predictive of HIV-D. These findings suggest that HAND are highly prevalent in primary care settings in South Africa where clade C HIV is predominant...
Neuropsychological outcomes in adults commencing highly active anti-retroviral treatment in South Africa: a prospective studyJohn A Joska
Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa
BMC Infect Dis 12:39. 2012
..To date, there have been no cohort studies of the impact of highly active anti-retroviral treatment (HAART) in South Africa where clade C HIV is predominant...
- Validity of the International HIV Dementia Scale in South Africa
John A Joska
Department of Psychiatry and Mental Health, University of Cape Town, South Africa
AIDS Patient Care STDS 25:95-101. 2011
..Variable performance in neuropsychological testing may account for false negative screens. The inclusion of brief tests of executive function in a screening battery should be considered...
- Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa
John A Joska
Department of Psychiatry and Mental Health, University of Cape Town, South Africa
J Neurovirol 16:377-83. 2010
..These findings suggest that the ε4 allelic variant in HIV-positive individuals is not associated with the development of HAD in Southern Africa...
