Manipulating the sleep-wake cycle and circadian rhythms to improve clinical management of major depressionIan B Hickie
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallett St, Camperdown, NSW, 2050, Australia
BMC Med 11:79. 2013
..Due to very considerable progress in the basic and clinical neurosciences of sleep-wake cycles and underlying circadian systems this situation is now rapidly changing...
- Applying clinical staging to young people who present for mental health care
Ian B Hickie
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, New South Wales
Early Interv Psychiatry 7:31-43. 2013
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- Novel melatonin-based therapies: potential advances in the treatment of major depression
Ian B Hickie
Brain and Mind Research Institute, The University of Sydney, Camperdown, NSW, Australia
Lancet 378:621-31. 2011
..As agomelatine does not raise serotonin levels, it has less potential for the common gastrointestinal, sexual, or metabolic side-effects that characterise many other antidepressant compounds...
The 2010 Rudd plan: will it actually deliver better health services?Ian B Hickie
Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
Med J Aust 192:511-2. 2010
- Youth mental health: we know where we are and we can now say where we need to go next
Ian B Hickie
Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
Early Interv Psychiatry 5:63-9. 2011
..To provide an overview of the state of knowledge relevant to the development of youth-specific mental health initiatives...
Neurophysiological biomarkers support bipolar-spectrum disorders within psychosis clusterManreena Kaur
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
J Psychiatry Neurosci 37:313-21. 2012
..Further research is warranted to determine whether patients with bipolar-spectrum disorders show similar impairments in these biomarkers...
- Reduced mismatch negativity in mild cognitive impairment: associations with neuropsychological performance
Loren Mowszowski
Ageing Brain Centre, Brain and Mind Research Institute, The University of Sydney, 94 Mallett Street, Camperdown, NSW 2050, Australia
J Alzheimers Dis 30:209-19. 2012
..These findings overall suggest that MMN may be a viable neurophysiological biomarker of underlying disease in this 'at risk' group...
- Reduced temporal mismatch negativity in late-life depression: an event-related potential index of cognitive deficit and functional disability?
Sharon L Naismith
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Australia
J Affect Disord 138:71-8. 2012
..This study examined MMN elicited by duration deviant stimuli in older people with lifetime depression, and explored its relationship with neuropsychological functioning and disability...
- Targeted primary care-based mental health services for young Australians
Elizabeth M Scott
Clinical Research Unit, Brain and Mind Research Institute, Sydney, NSW
Med J Aust 196:136-40. 2012
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- Impaired MMN/P3a complex in first-episode psychosis: cognitive and psychosocial associations
Daniel F Hermens
Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia
Prog Neuropsychopharmacol Biol Psychiatry 34:822-9. 2010
..Such deficits in FEP appear to have important links with higher-order cognitive and psychosocial functioning...
- Sleep disturbance relates to neuropsychological functioning in late-life depression
Sharon L Naismith
Clinical Research Unit, Brain and Mind Research Institute, Australia
J Affect Disord 132:139-45. 2011
..Sleep-wake disturbance in older people is a risk factor for depression onset and recurrence. The aim of this study was to determine if objective sleep-wake disturbance in late-life depression relates to neuropsychological functioning...
- Fronto-striatal correlates of impaired implicit sequence learning in major depression: an fMRI study
Sharon L Naismith
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
J Affect Disord 125:256-61. 2010
..This study sought to probe the integrity of fronto-striatal circuits using functional magnetic resonance imaging (fMRI) in conjunction with a theoretically-driven motor sequencing implicit learning (IL) task...
- MMN/P3a deficits in first episode psychosis: comparing schizophrenia-spectrum and affective-spectrum subgroups
Manreena Kaur
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
Schizophr Res 130:203-9. 2011
..First-episode psychosis (FEP) patients show reduced amplitudes of the 'MMN/P3a complex', but it is unclear whether this occurs across the FEP spectrum...
- Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes: an MRI study
Sean N Hatton
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
BMC Psychiatry 12:45. 2012
..This study examined the relationship between anterior insula GMV, clinical symptom severity and neuropsychological performance in a heterogeneous cohort of young people presenting for mental health care...
- Impaired verbal memory in young adults with unipolar and bipolar depression
Daniel F Hermens
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, New South Wales, Australia
Early Interv Psychiatry 4:227-33. 2010
..Specifically, deficits in verbal memory have been linked to depression in young people. This study examined whether young adults with unipolar compared with bipolar depression showed similar neurocognitive deficits...
- Does sleep disturbance mediate neuropsychological functioning in older people with depression?
Sharon L Naismith
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 94 Mallet Street, Camperdown NSW 2050, Australia
J Affect Disord 116:139-43. 2009
..However, the association between sleep disturbance and neuropsychological functioning in depression has not been well evaluated. The current study therefore aimed to investigate these relationships...
- The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathophysiological features
Sharon L Naismith
Ageing Brain Centre, Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
Prog Neurobiol 98:99-143. 2012
..Ultimately, future research must aim to evaluate whether basic biomedical knowledge can be successfully translated into enhanced health outcomes via the implementation of early intervention paradigms...
- Can older "at risk" adults benefit from psychoeducation targeting healthy brain aging?
Louisa M Norrie
Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, NSW, Australia
Int Psychogeriatr 23:413-24. 2011
..The current study sought to investigate whether older adults "at risk" of cognitive decline benefit from psychoeducation targeting healthy brain aging...
- Neuropsychological clustering highlights cognitive differences in young people presenting with depressive symptoms
Daniel F Hermens
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
J Int Neuropsychol Soc 17:267-76. 2011
..Distinct neuropsychological profiling may help to predict later psychiatric outcomes and enhance individually-tailored early intervention strategies...
- Sleep well, think well: sleep-wake disturbance in mild cognitive impairment
Sharon L Naismith
Ageing Brain Centre, Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
J Geriatr Psychiatry Neurol 23:123-30. 2010
..This preliminary data suggests that sleep-wake disturbance in nonamnestic forms of MCI is related to cognitive functioning and may be indicative of shared neurobiological underpinnings...
- Early intervention for cognitive decline: is there a role for multiple medical or behavioural interventions?
Sharon L Naismith
Brain and Mind Research Institute, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Early Interv Psychiatry 3:19-27. 2009
..Evidence for the beneficial effects of providing relevant interventions is assessed...
- Internet-based treatment for older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double-blind, placebo controlled trial
Nicole L Cockayne
Brain and Mind Research Institute, The University of Sydney, Camperdown NSW, Australia
BMC Psychiatry 11:10. 2011
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- Psychomotor slowing in older patients with major depression: Relationships with blood flow in the caudate nucleus and white matter lesions
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, Sydney, Australia
Psychiatry Res 155:211-20. 2007
..Reduced %rCBF is associated with demonstrable psychomotor slowing and presence of WMLs. While psychomotor slowing is determined in part by subcortical changes, other cortical and illness-dependent factors are likely to be relevant...
- Mental health expenditure in Australia: time for affirmative action
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, New South Wales
Aust N Z J Public Health 30:119-22. 2006
..Urgent investments in cost-effective modes of care are required and these should prioritise increased access among those subpopulations disadvantaged by other social, economic or geographic factors...
- Increased access to evidence-based primary mental health care: will the implementation match the rhetoric?
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
Med J Aust 187:100-3. 2007
..The responsibility for achieving the best outcome does not lie only with governments. To date, the professions have not placed enough emphasis on systematically adopting evidence-based forms of collaborative care...
- Microstructural white matter changes in the corpus callosum of young people with bipolar disorder: a diffusion tensor imaging study
Jim Lagopoulos
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
PLoS ONE 8:e59108. 2013
..Our findings provide evidence of microstructural white matter changes early in the course of illness within the corpus callosum and the nature of these changes suggest they are associated with abnormalities in the myelination of axons...
- The role of mild depression in sleep disturbance and quality of life in Parkinson's disease
Sharon L Naismith
Brain and Mind Research Institute, University of Sydney, Camperdown, New South Wales, Australia
J Neuropsychiatry Clin Neurosci 22:384-9. 2010
..Overall, these data highlight the need to screen patients for even mild levels of depression because its relationship with sleep and quality of life are evident early in the disease course...
- Cognitive training in affective disorders improves memory: a preliminary study using the NEAR approach
Sharon L Naismith
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, NSW, Australia
J Affect Disord 121:258-62. 2010
..Some of these changes persist despite antidepressant treatment. While research in other areas of psychiatry has shown cognitive training techniques to be effective, only one study has evaluated this approach in depression...
- Thoughts of death or suicidal ideation are common in young people aged 12 to 30 years presenting for mental health care
Elizabeth M Scott
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Camperdown, NSW 2050, Australia
BMC Psychiatry 12:234. 2012
..This study determines the socio-demographic, psychopathological and illness-stage correlates of suicidal ideation in young persons attending headspace services...
- The impact of gender on early ill-health retirement in people with heart disease and depression
Matt B Paradise
Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
Aust N Z J Psychiatry 46:249-56. 2012
..Given the deleterious effects of ill-health retirement, identifying at-risk groups is important for guiding targeted interventions...
- Alcohol use and mismatch negativity in young patients with psychotic disorder
Kate M Chitty
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
Neuroreport 22:918-22. 2011
..This may reflect an additive effect of N-methyl-D-aspartate receptor hypofunction and high-alcohol consumption...
- Frontal lobe changes occur early in the course of affective disorders in young people
Jim Lagopoulos
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
BMC Psychiatry 12:4. 2012
..Contrasts were carried out between controls subjects and patients cohorts with attenuated syndromes and discrete disorders, separately...
- Enhancing memory in late-life depression: the effects of a combined psychoeducation and cognitive training program
Sharon L Naismith
Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, NSW, Australia
Am J Geriatr Psychiatry 19:240-8. 2011
..To evaluate the efficacy of a multifactorial cognitive training (CT) program for older people with a lifetime history of depressive disorder...
- Recognition and treatment of depression: a comparison of Australian and Chinese medical students
Ye Rong
Brain and Mind Research Institute, The University of Sydney, Camperdown NSW 2050, Australia
Soc Psychiatry Psychiatr Epidemiol 44:636-42. 2009
..To improve services, we need to ensure health professionals have an appropriate understanding of depression and its treatments. This study compares the level of awareness of depression between Chinese and Australian medical students...
- Disability is already pronounced in young people with early stages of affective disorders: data from an early intervention service
Blake A Hamilton
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, 2050 Australia
J Affect Disord 131:84-91. 2011
..This study examined patient self-reported disability in young people attending a designated early intervention service...
- Neuropsychological and socio-occupational functioning in young psychiatric outpatients: a longitudinal investigation
Rico S C Lee
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
PLoS ONE 8:e58176. 2013
..The current study extended these findings to young and early-course psychiatric outpatients, with the aim of identifying cognitive markers that predict later socio-occupational functioning...
- Arginine Vasopressin selectively enhances recognition of sexual cues in male humans
Adam J Guastella
Brain and Mind Research Institute, University of Sydney, Camperdown, Sydney, NSW, Australia
Psychoneuroendocrinology 36:294-7. 2011
..They further extend animal and human genetic studies linking Arginine Vasopressin to sexual behavior in males. Findings suggest an important cognitive mechanism that could enhance sexual behaviors in humans...
- The relationship between actigraphically defined sleep disturbance and REM sleep behaviour disorder in Parkinson's Disease
Sharon L Naismith
Parkinson s Disease Research Clinic, Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, 94 Mallett St, Camperdown, NSW 2050, Australia
Clin Neurol Neurosurg 112:420-3. 2010
..In this study, we sought to evaluate the utility of actigraphy for examining symptoms of rapid eye movement sleep behaviour disorder (RSBD)...
- Delayed preattentional functioning in early psychosis patients with cannabis use
Nicole Pesa
School of Psychology, University of Wollongong, Wollongong, NSW, 2522, Australia
Psychopharmacology (Berl) 222:507-18. 2012
..The event-related potentials, mismatch negativity (MMN) and P3a are reduced in EP. Cannabinoids have been shown to modulate N-methyl-D-aspartate receptors which are involved in MMN generation...
- Improving knowledge and attitudes towards depression: a controlled trial among Chinese medical students
Ye Rong
Brain and Mind Research Institute, The University of Sydney, Sydney, Australia
BMC Psychiatry 11:36. 2011
..The purpose of this study was to determine whether a self-directed learning strategy as a part of student-centred education improved knowledge of and attitudes towards depression among Chinese medical students...
- A systematic review of the impact of adherence on the effectiveness of e-therapies
Liesje Donkin
Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
J Med Internet Res 13:e52. 2011
..Understanding the role of adherence may be crucial to understanding how program usage influences the effectiveness of e-therapy interventions...
- How does social functioning in the early stages of psychosis relate to depression and social anxiety?
Catherine Chudleigh
Clinical Research Unit, Brain and Mind Research Institute, New South Wales, Australia
Early Interv Psychiatry 5:224-32. 2011
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- Delayed sleep phase in young people with unipolar or bipolar affective disorders
Rébecca Robillard
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, New South Wales, Australia
J Affect Disord 145:260-3. 2013
..Despite marked changes in circadian rhythms during the normal course of adolescence and young adulthood, less is known about changes in the 24-h sleep-wake cycle in young persons with mood disorders...
- Practitioner-supported delivery of internet-based cognitive behaviour therapy: evaluation of the feasibility of conducting a cluster randomised trial
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
Med J Aust 192:S31-5. 2010
..To determine the feasibility of conducting a cluster randomised trial in Australia of the effectiveness of general practitioner-supported delivery of internet-based cognitive behaviour therapy (CBT) and enhanced psychological care...
- Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders
Adam J Guastella
Brain and Mind Research Institute, University of Sydney, Sydney, NSW 2050, Australia
Biol Psychiatry 67:692-4. 2010
..Deficits in the ability to recognize the emotions of others are believed to contribute to this. There is currently no effective treatment for these problems...
- Distinguishing young people with emerging bipolar disorders from those with unipolar depression
Elizabeth M Scott
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Camperdown, NSW 2050, Australia
J Affect Disord 144:208-15. 2013
..To facilitate early intervention, there is a need to distinguish unipolar versus bipolar illness trajectories in adolescents and young adults with adult-type mood disorders...
- Clinical staging model applied to young people presenting with social anxiety
Patrick J F Clarke
Brain and Mind Research Institute, University of Sydney, Sydney, New South Wales, Australia
Early Interv Psychiatry 6:256-64. 2012
..The goal was to provide a detailed description of common clinical stage of those presenting for treatment of social anxiety, and to delineate the associations between symptom type, severity and clinical stage...
- Mismatch negativity/P3a complex in young people with psychiatric disorders: a cluster analysis
Manreena Kaur
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
PLoS ONE 7:e51871. 2012
..A data driven approach may help to further elucidate novel patterns of MMN/P3a amplitudes that characterise distinct subgroups in patients with emerging psychiatric disorders...
- Disability in major depression related to self-rated and objectively-measured cognitive deficits: a preliminary study
Sharon L Naismith
Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
BMC Psychiatry 7:32. 2007
..This study examined the relationships between self-rated disability in persons with MD and both self-rated and objectively-measured cognitive functioning...
- Responding to experiences of young people with common mental health problems attending Australian general practice
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
Med J Aust 187:S47-52. 2007
..Improved access to specific psychological treatments should remain a priority...
- Perspectives of young people on depression: awareness, experiences, attitudes and treatment preferences
Ian B Hickie
Brain and Mind Research Institute, The University of Sydney, Camperdown, Sydney, New South Wales, Australia
Early Interv Psychiatry 1:333-9. 2007
..Ascertaining current knowledge and attitudes towards depression among young people is vital for developing campaigns promoting community awareness and early intervention...
- Australian mental health reform: time for real outcomes
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, PO Box M160, Camperdown, NSW 2050, Australia
Med J Aust 182:401-6. 2005
..New independent and national reporting systems on the progress of mental health reform are urgently required...
- Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, 100 Mallett Street, Camperdown, NSW 2050, Australia
J Affect Disord 98:137-42. 2007
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- Can we track the impact of Australian mental health research?
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, New South Wales, Australia
Aust N Z J Psychiatry 39:591-9. 2005
..Specifically, we describe the research output of nations, Australian states, Australian and New Zealand institutions and Australian and New Zealand researchers using citation rates...
- Young men, mental health, and technology: implications for service design and delivery in the digital age
Louise A Ellis
Brain and Mind Research Institute, Faculty of Medicine, University of Sydney, Sydney, Australia
J Med Internet Res 14:e160. 2012
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- A preliminary study of aged care facility staff indicates limitations in awareness of the link between depression and physical morbidity
Joanna Atkins
Brain and Mind Research Institute, University of Sydney, 94 Mallett Street, Camperdown, NSW, 2050, Australia
BMC Geriatr 13:30. 2013
..This study assessed the awareness and knowledge of age-care staff of the link between physical morbidity and depression...
- Oxytocin increases heart rate variability in humans at rest: implications for social approach-related motivation and capacity for social engagement
Andrew H Kemp
School of Psychology, University of Sydney, Sydney, New South Wales, Australia
PLoS ONE 7:e44014. 2012
..Furthermore, no studies have examined the impact of OT on HRV under resting conditions, which provides an index of maximal capacity for social engagement...
- Intranasal arginine vasopressin enhances the encoding of happy and angry faces in humans
Adam J Guastella
Brain and Mind Research Institute, University of Sydney, Sydney, Australia
Biol Psychiatry 67:1220-2. 2010
..There has been little research in humans exploring its effect on social cognition, including the encoding of social memories...
- What can alert the general practitioner to people whose common mental health problems are unrecognised?
Kay A Wilhelm
Consultation Liaison Psychiatry, St Vincent s Hospital, Sydney, NSW, Australia
Med J Aust 188:S114-8. 2008
..To assess the characteristics of people with common mental health problems who are recognised by their general practitioner, and those who are not...
- Pathways to alcohol-induced brain impairment in young people: a review
Daniel F Hermens
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
Cortex 49:3-17. 2013
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- Heart rate variability is associated with emotion recognition: direct evidence for a relationship between the autonomic nervous system and social cognition
Daniel S Quintana
SCAN Research and Teaching Unit, School of Psychology, University of Sydney, Australia
Int J Psychophysiol 86:168-72. 2012
..Our data suggests that increased HRV may provide a novel marker of one's ability to recognize emotions in humans. Implications for understanding the biological basis of emotion recognition, and social impairment in humans are discussed...
- Subjective memory complaints, vascular risk factors and psychological distress in the middle-aged: a cross-sectional study
Matt B Paradise
Brain and Mind Research Institute, The University of Sydney, Camperdown, NSW 2050, Australia
BMC Psychiatry 11:108. 2011
..We therefore aimed to test the hypothesis that vascular risk factors were associated with SMC, independent of psychological distress, in a middle-aged community-dwelling population...
- Amphetamine psychosis: a model for studying the onset and course of psychosis
Daniel F Hermens
Brain and Mind Research Institute, University of Sydney, Sydney, NSW
Med J Aust 190:S22-5. 2009
..It is possible that the same approach may be used in young people known to be at risk of schizophrenia and related disorders, by informing models that involve other environmental or genetic risks...
- Were the budgetary reforms to the Better Access to Mental Health Care initiative appropriate?--no
Sebastian Rosenberg
Brain and Mind Research Institute, University of Sydney, Sydney, NSW sebastian rosenbergATsydney edu au
Med J Aust 194:595. 2011
..Mental health policy expert Sebastian Rosenberg and psychiatrist Ian Hickie want more change...
- Neuropsychological performance in patients with depression is associated with clinical, etiological and genetic risk factors
Sharon L Naismith
School of Psychiatry, University of New South Wales, Sydney, Australia
J Clin Exp Neuropsychol 25:866-77. 2003
..These findings underscore the need to consider subtypes when investigating neuropsychological deficits in patients with depression...
- Identification and management of depression in Australian primary care and access to specialist mental health care
Nicholas Glozier
Brain and Mind Research Institute, Sydney Medical School, University of Sydney, 94 Mallett St, Camperdown, New South Wales 2050, Australia
Psychiatr Serv 63:1247-51. 2012
..The authors evaluated management of illness, including access to specialist mental health care, among people identified by general practitioners as clinically depressed...
- Oxytocin selectively moderates negative cognitive appraisals in high trait anxious males
Gail A Alvares
Brain and Mind Research Institute, University of Sydney, 100 Mallett St, Camperdown, NSW 2050, Australia
Psychoneuroendocrinology 37:2022-31. 2012
..It adds to a growing body of evidence that oxytocin seems to attenuate negative cognitive responses to stress in anxious individuals...
- Therapeutic signposts: using biomarkers to guide better treatment of schizophrenia and other psychotic disorders
Richard Banati
Brain and Mind Research Institute, University of Sydney, Sydney, NSW
Med J Aust 190:S26-32. 2009
..A specific example of the use of a novel positron emission tomography marker of progressive brain disease in patients with schizophrenia is described...
- Effect of oral appliance therapy on neurobehavioral functioning in obstructive sleep apnea: a randomized controlled trial
Sharon L Naismith
Department of Respiratory and Sleep Medicine, St George Hospital, The University of New South Wales, Sydney, Australia
J Clin Sleep Med 1:374-80. 2005
..This study aimed to assess the efficacy of a custom-made mandibular advancement splint for the treatment of obstructive sleep apnea with respect to neuropsychological functioning and mood state...
- Acute effects of intranasal oxytocin on subjective and behavioral responses to social rejection
Gail A Alvares
Brain and Mind Research Institute, University of Sydney, NSW, Australia
Exp Clin Psychopharmacol 18:316-21. 2010
..The results suggest that in an explicitly aversive context, oxytocin does not buffer against the immediate impact of blunt social rejection...
- Impaired implicit sequence learning in depression: a probe for frontostriatal dysfunction?
Sharon L Naismith
Brain and Mind Research Institute, University of Sydney, Sydney, Australia
Psychol Med 36:313-23. 2006
..Consequently, it is ideally suited for testing elements of the frontostriatal model of major depression and performance can be related to key clinical, neuropsychological, vascular and biochemical data...
- Electroconvulsive therapy-induced persistent retrograde amnesia: could it be minimised by ketamine or other pharmacological approaches?
Emily M Gregory-Roberts
Brain and Mind Research Institute, University of Sydney, Australia
J Affect Disord 126:39-45. 2010
..This review examines mechanisms for electroconvulsive therapy-induced retrograde amnesia, and evaluates the suitability of the anaesthetic ketamine for preventing this amnestic outcome...
- Effect of sertraline on symptoms and survival in patients with advanced cancer, but without major depression: a placebo-controlled double-blind randomised trial
Martin R Stockler
NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia
Lancet Oncol 8:603-12. 2007
..We aimed to identify the effects of an established antidepressant on these symptoms and survival in patients with advanced cancer who did not have major depression as assessed by clinicians...
- Reducing the burden of depression: are we making progress in Australia?
Ian B Hickie
Brain and Mind Research Institute, The University of Sydney, PO Box M160, Camperdown, NSW 1450, Australia
Med J Aust 181:S4-5. 2004
- Making new choices about antidepressants in Australia: the long view 1975-2002
Andrea Mant
Quality Use of Medicines, South East Health, Sydney Hospital, PO Box 1614, Sydney, NSW 2001, Australia
Med J Aust 181:S21-4. 2004
..To examine trends in types of antidepressant medications prescribed in Australia between 1975 and 2002...
- General practitioners' response to depression and anxiety in the Australian community: a preliminary analysis
Ian B Hickie
Brain and Mind Research Institute, University of Sydney, NSW 2039, Australia
Med J Aust 181:S15-20. 2004
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- Measuring outcomes in patients with depression or anxiety: an essential part of clinical practice
Ian B Hickie
School of Psychiatry, University of New South Wales at St George Hospital, Sydney, NSW
Med J Aust 177:205-7. 2002
..As depression and anxiety are relapsing or chronic conditions and are often comorbid with other medical conditions, standard outcome measures should be incorporated into the management plans for all such patients...
