Brian J Hicke

Summary

Publications

  1. ncbi Tumor targeting by an aptamer
    Brian J Hicke
    NeXstar Pharmaceuticals, Boulder, Colorado, USA
    J Nucl Med 47:668-78. 2006
  2. ncbi A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment
    Dion A Daniels
    Gene Expression and Protein Biochemistry, GlaxoSmithKline Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, England
    Proc Natl Acad Sci U S A 100:15416-21. 2003

Collaborators

  • Dion A Daniels
  • Hang Chen
  • Larry Gold
  • Kristine M Swiderek

Detail Information

Publications2

  1. ncbi Tumor targeting by an aptamer
    Brian J Hicke
    NeXstar Pharmaceuticals, Boulder, Colorado, USA
    J Nucl Med 47:668-78. 2006
    ..Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a target molecule. We sought to determine whether aptamers have potential for in vivo delivery of radioisotopes or cytotoxic agents...
  2. ncbi A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment
    Dion A Daniels
    Gene Expression and Protein Biochemistry, GlaxoSmithKline Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, England
    Proc Natl Acad Sci U S A 100:15416-21. 2003
    ..Systematic evolution of ligands by exponential enrichment appears to be a successful strategy for the a priori identification of targets of biological interest within complex systems...