Kenji Hibiya

Summary

Publications

  1. ncbi request reprint Acquired immune-deficiency syndrome with focal onset of Mycobacterium avium infection displaying a histological/genetic pattern of disseminated mycobacteria
    Kenji Hibiya
    Department of Infections, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, and Department of Clinical Research, National Hospital Organization, Higashinagoya National Hospital, Japan
    Intern Med 51:3089-94. 2012
  2. doi request reprint Distribution of mycobacterial antigen based on differences of histological characteristics in pulmonary Mycobacterium avium infectious diseases--consideration of the extent of surgical resection from the pathological standpoint
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of Ryukyus, 270 Uehara, Nishihara, Nakagami gun, Okinawa, Japan
    Pathol Res Pract 208:53-8. 2012
  3. ncbi request reprint [The pathogenesis of the bowel infection with the Mycobacterium tuberculosis]
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Kekkaku 85:711-21. 2010
  4. doi request reprint Immunopathological characteristics of immune reconstitution inflammatory syndrome caused by Mycobacterium parascrofulaceum infection in a patient with AIDS
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    Pathol Res Pract 207:262-70. 2011
  5. doi request reprint Descriptive analysis of the prevalence and the molecular epidemiology of Mycobacterium avium complex-infected pigs that were slaughtered on the main island of Okinawa
    K Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    Comp Immunol Microbiol Infect Dis 33:401-21. 2010
  6. ncbi request reprint Mechanisms involved in the extension of pulmonary Mycobacterium avium infection from the pulmonary focus to the regional lymph nodes
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Nakagami gun, Okinawa, Japan
    Kekkaku 86:1-8. 2011
  7. pmc Pathogenesis of systemic Mycobacterium avium infection in pigs through histological analysis of hepatic lesions
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan
    Can J Vet Res 74:252-7. 2010
  8. ncbi request reprint Pulmonary Mycobacterium parascrofulaceum infection as an immune reconstitution inflammatory syndrome in an AIDS patient
    Hiromitsu Teruya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Intern Med 49:1817-21. 2010
  9. ncbi request reprint [Mycobacteriosis as zoonotic disease--comparative pathological study on Mycobacterium avium complex infection]
    Kenji Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa 903 0215, Japan
    Kekkaku 82:539-50. 2007
  10. ncbi request reprint [The pathogenesis and the development mechanism of Mycobacterium avium complex infection]
    Kenji Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Kekkaku 82:903-18. 2007

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Acquired immune-deficiency syndrome with focal onset of Mycobacterium avium infection displaying a histological/genetic pattern of disseminated mycobacteria
    Kenji Hibiya
    Department of Infections, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, and Department of Clinical Research, National Hospital Organization, Higashinagoya National Hospital, Japan
    Intern Med 51:3089-94. 2012
    ..The patient's baseline CD4+ cell count was 9/μL and the HIV-RNA viral load was 43,800 copies/mL. This case suggests the possibility of a localized onset of disseminated M. avium infection...
  2. doi request reprint Distribution of mycobacterial antigen based on differences of histological characteristics in pulmonary Mycobacterium avium infectious diseases--consideration of the extent of surgical resection from the pathological standpoint
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of Ryukyus, 270 Uehara, Nishihara, Nakagami gun, Okinawa, Japan
    Pathol Res Pract 208:53-8. 2012
    ..This is the first study to quantitatively evaluate mycobacterial antigens according to histological characteristics in MAC pulmonary disease...
  3. ncbi request reprint [The pathogenesis of the bowel infection with the Mycobacterium tuberculosis]
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Kekkaku 85:711-21. 2010
    ....
  4. doi request reprint Immunopathological characteristics of immune reconstitution inflammatory syndrome caused by Mycobacterium parascrofulaceum infection in a patient with AIDS
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    Pathol Res Pract 207:262-70. 2011
    ..Our data provide the first evidence to reveal the status of the axis of distinctive immunity in the process of granuloma formation caused by a mycobacterium-related infection...
  5. doi request reprint Descriptive analysis of the prevalence and the molecular epidemiology of Mycobacterium avium complex-infected pigs that were slaughtered on the main island of Okinawa
    K Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    Comp Immunol Microbiol Infect Dis 33:401-21. 2010
    ..However, the outbreaks occurred because of unspecified conditions on each farm environment...
  6. ncbi request reprint Mechanisms involved in the extension of pulmonary Mycobacterium avium infection from the pulmonary focus to the regional lymph nodes
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Nakagami gun, Okinawa, Japan
    Kekkaku 86:1-8. 2011
    ..This study was designed to evaluate the mechanism of Mycobacterium avium extension in lung infection...
  7. pmc Pathogenesis of systemic Mycobacterium avium infection in pigs through histological analysis of hepatic lesions
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan
    Can J Vet Res 74:252-7. 2010
    ..These findings suggest that granulomatous lesions formed in hepatic lobules upon establishment of bacteremia in pigs systemically infected with M. avium...
  8. ncbi request reprint Pulmonary Mycobacterium parascrofulaceum infection as an immune reconstitution inflammatory syndrome in an AIDS patient
    Hiromitsu Teruya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Intern Med 49:1817-21. 2010
    ..parascrofulaceum infection was not observed. M. parascrofulaceum was isolated from several clinical specimens for the first time in 2004. To date, only five cases have been reported...
  9. ncbi request reprint [Mycobacteriosis as zoonotic disease--comparative pathological study on Mycobacterium avium complex infection]
    Kenji Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa 903 0215, Japan
    Kekkaku 82:539-50. 2007
    ..Since the pathogenesis of human MAC respiratory infection has not been well clarified, it may be very important to examine the mechanism of pig MAC infection to find out some clues to explain the mechanism of human MAC infection...
  10. ncbi request reprint [The pathogenesis and the development mechanism of Mycobacterium avium complex infection]
    Kenji Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Kekkaku 82:903-18. 2007
    ..In this review, we specifically discuss the development mechanism of disseminated MAC disease in recently-identified several pathological conditions...
  11. pmc Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone
    Makoto Furugen
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara Town, Okinawa 903 0215, Japan
    Respir Res 9:39. 2008
    ..In this study, we investigated the precise mechanism by which A549 alveolar epithelial cells induced by L. pneumophila undergo apoptosis. We also studied the effect of methyl prednisolone on apoptosis in these cells...
  12. ncbi request reprint Depression of local cell-mediated immunity and histological characteristics of disseminated AIDS-related Mycobacterium avium infection after the initiation of antiretroviral therapy
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Japan
    Intern Med 52:1793-803. 2013
    ..The aim of the present study was to examine the immunohistological characteristics of disseminated Mycobacterium avium infection after the initiation of antiretroviral therapy (ART) for acquired immunodeficiency syndrome (AIDS)...
  13. ncbi request reprint Organizing pneumonia pattern in the follow-up CT of Legionella-infected patients
    Attiya Haroon
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa, 903 0125, Japan
    J Infect Chemother 17:493-8. 2011
    ..Interlobular septal thickening was seen in one patient. Pleural effusion was seen in one patient. The CT pattern of organizing pneumonia, a subpleural pattern, was frequently observed after treatment of L. pneumophila pneumonia...
  14. pmc Hepatocyte growth factor levels in Legionella pneumonia: a retrospective study
    Futoshi Higa
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
    BMC Infect Dis 11:74. 2011
    ..Legionella pneumonia is sometimes complicated by acute lung injury. Our study aimed to determine the role of serum HGF levels in Legionella pneumonia...
  15. doi request reprint Repetitive element-polymerase chain reaction for genotyping of clinical and environmental isolates of Legionella spp
    Attiya Haroon
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Diagn Microbiol Infect Dis 68:7-12. 2010
    ..anisa isolates, while other Legionella spp. were present at discrete levels. Our findings show that rep-PCR is an effective, rapid, and simple technique for differentiation of L. pneumophila strains as well as Legionella spp...
  16. ncbi request reprint [Overview of respiratory infection caused by nontuberculous mycobacteria]
    Jiro Fujita
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa 903 0215, Japan
    Kekkaku 82:721-7. 2007
    ..In addition, disseminated MAC disease in patients with acquired immunodeficiency syndrome should be considered. Further studies concerning transmission route as well as mechanism of MAC disease should be performed...
  17. doi request reprint Pigs as an experimental model for systemic Mycobacterium avium infectious disease
    Kenji Hibiya
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
    Comp Immunol Microbiol Infect Dis 34:455-64. 2011
    ..In conclusion, MAC infections in AIDS patients and pigs show similarities in terms of the initial route of infection and the genetic characteristics of the pathogenic strains...
  18. ncbi request reprint Histopathological classification of systemic Mycobacterium avium complex infections in slaughtered domestic pigs
    Kenji Hibiya
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    Comp Immunol Microbiol Infect Dis 31:347-66. 2008
    ....
  19. ncbi request reprint Detection of Legionella pneumophila serogroup 1 antigen in respiratory samples using an immunochromatographic membrane test
    Futoshi Higa
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, University of the Ryukyus, Okinawa 903 0215, Japan
    J Microbiol Methods 74:121-2. 2008
    ..The ICT results using respiratory samples agreed well with isolation of L. pneumophila SG1 and ICT using urines...
  20. doi request reprint Nonspecific interstitial pneumonia pattern as pulmonary involvement in human T-cell lymphotropic virus type 1 carriers
    Hui Yu
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa 903 0215, Japan
    J Infect Chemother 15:284-7. 2009
    ..The present study demonstrates that the NSIP pattern is a significant pathological classification of interstitial pneumonia associated with HTLV-1 carriers...
  21. pmc A case of pulmonary and hepatic cystic Echinococcosis of CE1 stage in a healthy Japanese female that was suspected to have been acquired during her stay in the United Kingdom
    Kiwamu Nakamura
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Nishihara, Japan
    Am J Trop Med Hyg 85:456-9. 2011
    ..This case is the first case report of a Japanese patient who had concomitant giant lung and liver CE with early-stage CE1 and was successfully treated by surgery and pharmacotherapy with a serological follow-up...
  22. ncbi request reprint Assessment of serum anti-Bordetella pertussis antibody titers among medical staff members
    Futoshi Higa
    Infection Control Team, Ryukyu University Hospital, Okinawa 903 0215, Japan
    Jpn J Infect Dis 61:371-4. 2008
    ..Prompt and accurate diagnostic tools are crucial for infection control in the hospital setting...
  23. pmc Diagnosis of intestinal tuberculosis using a monoclonal antibody to Mycobacterium tuberculosis
    Yasushi Ihama
    Department of Infectious, Respiratory, and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
    World J Gastroenterol 18:6974-80. 2012
    ..To investigate the utility of immunohistochemical (IHC) staining with an antibody to Mycobacterium tuberculosis (M. tuberculosis) for the diagnosis of intestinal tuberculosis (TB)...