Daniel Hesselson

Summary

Publications

  1. ncbi Suppression of Ptf1a activity induces acinar-to-endocrine conversion
    Daniel Hesselson
    Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics, and Human Genetics, Institute for Regeneration Medicine, Liver Center, and Diabetes Center, University of California, San Francisco, 1550 Fourth Street, San Francisco, CA 94158, USA
    Curr Biol 21:712-7. 2011
  2. ncbi Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration
    Ryan M Anderson
    Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics, and Human Genetics, Diabetes Center, and Liver Center, University of California, San Francisco, San Francisco, CA 94158 2324, USA
    Dev Biol 334:213-23. 2009
  3. ncbi Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling
    Daniel Hesselson
    Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, Institute for Regeneration Medicine, Liver Center and Diabetes Center, University of California, 1550 Fourth Street, San Francisco, CA 94158, USA
    Proc Natl Acad Sci U S A 106:14896-901. 2009

Detail Information

Publications3

  1. ncbi Suppression of Ptf1a activity induces acinar-to-endocrine conversion
    Daniel Hesselson
    Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics, and Human Genetics, Institute for Regeneration Medicine, Liver Center, and Diabetes Center, University of California, San Francisco, 1550 Fourth Street, San Francisco, CA 94158, USA
    Curr Biol 21:712-7. 2011
    ..These data indicate that targeted postembryonic disruption of the acinar cell fate can restore the developmental plasticity that is lost during development...
  2. ncbi Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration
    Ryan M Anderson
    Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics, and Human Genetics, Diabetes Center, and Liver Center, University of California, San Francisco, San Francisco, CA 94158 2324, USA
    Dev Biol 334:213-23. 2009
    ..In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors or the reprogramming of cells toward the pancreatic beta cell fate...
  3. ncbi Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling
    Daniel Hesselson
    Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, Institute for Regeneration Medicine, Liver Center and Diabetes Center, University of California, 1550 Fourth Street, San Francisco, CA 94158, USA
    Proc Natl Acad Sci U S A 106:14896-901. 2009
    ..g., diabetes mellitus). Our data reveal the existence of distinct populations of beta-cells in vivo and should help develop better strategies to regulate beta-cell differentiation and proliferation...