Brenda R Hemmelgarn

Summary

Publications

  1. pmc Comparative safety of anti-epileptic drugs among infants and children exposed in utero or during breastfeeding: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, Ontario M5B 1 T8, Canada
    Syst Rev 3:68. 2014
  2. pmc Safety and effectiveness of antiretroviral therapies for HIV-infected women and their infants and children: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, ON M5B 1 T8, Canada
    Syst Rev 3:51. 2014
  3. pmc Safety, effectiveness, and cost of long-acting versus intermediate-acting insulin for type 1 diabetes: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Room 716, Toronto, ON M5B 1T8, Canada
    Syst Rev 2:73. 2013
  4. pmc The VITAH trial VITamin D supplementation and cardiac Autonomic tone in Hemodialysis: a blinded, randomized controlled trial
    Michelle C Mann
    Department of Medicine, University of Calgary, 1403 29th St, NW, Room C210D, T2N 2 T9 Calgary, Alberta, Canada
    BMC Nephrol 15:129. 2014
  5. pmc Sociodemographic correlates of 25-hydroxyvitamin D test utilization in Calgary, Alberta
    Lawrence de Koning
    Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada
    BMC Health Serv Res 14:339. 2014
  6. pmc The association of income with health behavior change and disease monitoring among patients with chronic disease
    David J T Campbell
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e94007. 2014
  7. pmc Association between perceived unmet health care needs and risk of adverse health outcomes among patients with chronic medical conditions
    Paul E Ronksley
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Open Med 7:e21-30. 2013
  8. pmc Experiences of French speaking immigrants and non-immigrants accessing health care services in a large Canadian city
    Emmanuel Ngwakongnwi
    Health Quality Council of Alberta, 210, 811 14 Street NW, Calgary, Alberta, T2N 2A4, Canada
    Int J Environ Res Public Health 9:3755-68. 2012
  9. pmc Patterns of engagement with the health care system and risk of subsequent hospitalization amongst patients with diabetes
    Paul E Ronksley
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary, Calgary, Canada
    BMC Health Serv Res 13:399. 2013
  10. pmc Safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery and chemotherapy: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Room 716, Toronto, Ontario M5B 1T8, Canada
    Syst Rev 2:46. 2013

Detail Information

Publications124 found, 100 shown here

  1. pmc Comparative safety of anti-epileptic drugs among infants and children exposed in utero or during breastfeeding: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, Ontario M5B 1 T8, Canada
    Syst Rev 3:68. 2014
    ....
  2. pmc Safety and effectiveness of antiretroviral therapies for HIV-infected women and their infants and children: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, ON M5B 1 T8, Canada
    Syst Rev 3:51. 2014
    ..We aim to evaluate the comparative safety and effectiveness of the use of antiretroviral drugs among HIV-infected women and the effects on their infants and children through a systematic review and network meta-analysis...
  3. pmc Safety, effectiveness, and cost of long-acting versus intermediate-acting insulin for type 1 diabetes: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Room 716, Toronto, ON M5B 1T8, Canada
    Syst Rev 2:73. 2013
    ..Our objective is to evaluate the comparative effectiveness, safety, and cost of long-acting insulin versus intermediate-acting insulin through a systematic review and network meta-analysis...
  4. pmc The VITAH trial VITamin D supplementation and cardiac Autonomic tone in Hemodialysis: a blinded, randomized controlled trial
    Michelle C Mann
    Department of Medicine, University of Calgary, 1403 29th St, NW, Room C210D, T2N 2 T9 Calgary, Alberta, Canada
    BMC Nephrol 15:129. 2014
    ....
  5. pmc Sociodemographic correlates of 25-hydroxyvitamin D test utilization in Calgary, Alberta
    Lawrence de Koning
    Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada
    BMC Health Serv Res 14:339. 2014
    ..In this paper we examine this question by combining laboratory information system data on testing rates with Census Canada data...
  6. pmc The association of income with health behavior change and disease monitoring among patients with chronic disease
    David J T Campbell
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e94007. 2014
    ..We sought to determine the association between household income and receipt of health behavior change advice, adherence to advice, receipt of recommended monitoring tests, and self-reported reasons for non-adherence/non-receipt...
  7. pmc Association between perceived unmet health care needs and risk of adverse health outcomes among patients with chronic medical conditions
    Paul E Ronksley
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Open Med 7:e21-30. 2013
    ..Adults with chronic medical conditions are more likely to report unmet health care needs. Whether unmet health care needs are associated with an increased risk of adverse health outcomes is unclear...
  8. pmc Experiences of French speaking immigrants and non-immigrants accessing health care services in a large Canadian city
    Emmanuel Ngwakongnwi
    Health Quality Council of Alberta, 210, 811 14 Street NW, Calgary, Alberta, T2N 2A4, Canada
    Int J Environ Res Public Health 9:3755-68. 2012
    ..This study provided the groundwork for future research on health issues of official language minorities in Canada...
  9. pmc Patterns of engagement with the health care system and risk of subsequent hospitalization amongst patients with diabetes
    Paul E Ronksley
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary, Calgary, Canada
    BMC Health Serv Res 13:399. 2013
    ..We sought to determine the association between patterns of health care engagement and risk of subsequent hospitalization within one year of discharge for patients with diabetes...
  10. pmc Safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery and chemotherapy: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Room 716, Toronto, Ontario M5B 1T8, Canada
    Syst Rev 2:46. 2013
    ..To examine this further, we are proposing to conduct a systematic review and network meta-analysis on the comparative safety of 5-HT3 receptor antagonists among patients undergoing chemotherapy or surgery...
  11. pmc Safety, effectiveness, and cost of dipeptidyl peptidase-4 inhibitors versus intermediate acting insulin for type 2 diabetes: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, Ontario M5B 1T8, Canada
    Syst Rev 2:47. 2013
    ..As such, our objective is to evaluate the comparative effectiveness, safety and cost-effectiveness of DPP-4 inhibitors versus intermediate acting insulin for T2DM patients who have failed both first- and second-line diabetes treatments...
  12. pmc Interventions to decrease the risk of adverse cardiac events for post-surgery or chemotherapy patients taking serotonin (5-HT3) receptor antagonists: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St Michael s Hospital, 209 Victoria Street, East Building, Toronto, ON M5B 1 T8, Canada
    Syst Rev 2:45. 2013
    ....
  13. pmc Use of cognitive enhancers for mild cognitive impairment: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, ON, M5B 1T8, Canada
    Syst Rev 1:25. 2012
    ..We aimed to determine the comparative effectiveness, safety, and cost of cognitive enhancers for MCI through a systematic review and network (that is, indirect comparisons) meta-analysis...
  14. pmc Efficacy of cognitive enhancers for Alzheimer's disease: protocol for a systematic review and network meta-analysis
    Andrea C Tricco
    Li Ka Shing Knowledge Institute, St, Michael s Hospital, 209 Victoria Street, East Building, Toronto, ON, M5B 1T8, Canada
    Syst Rev 1:31. 2012
    ..Our objective is to evaluate the comparative effectiveness, safety, and cost of cognitive enhancers for Alzheimer's disease through a systematic review...
  15. pmc Association of vitamin D status with socio-demographic factors in Calgary, Alberta: an ecological study using Census Canada data
    Christopher Naugler
    Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Public Health 13:316. 2013
    ..The purpose of this study was to use a novel methodology of inferring sociodemographic variables to evaluate the correlates of vitamin D levels in individuals dwelling in the City of Calgary, Alberta, Canada...
  16. pmc Young aboriginals are less likely to receive a renal transplant: a Canadian national study
    Steven Promislow
    Department of Medicine, Section of Nephrology, St Boniface Hospital, University of Manitoba, 409 Tache Avenue, Winnipeg R2H 2A6, Canada
    BMC Nephrol 14:11. 2013
    ..We examined the effect of age on renal transplantation in Aboriginals...
  17. pmc Evaluating the impact of a novel restricted reimbursement policy for quinolone antibiotics: a time series analysis
    Braden Manns
    Department of Medicine, Calgary, Alberta, Canada
    BMC Health Serv Res 12:290. 2012
    ..We conducted an observational study to determine the impact of this new formulary restriction policy on antimicrobial prescription rates as well as any clinical consequences...
  18. pmc Assessment of the Siksika chronic disease nephropathy-prevention clinic
    David R R Ward
    Department of Medicine, University of Calgary, Alberta
    Can Fam Physician 59:e19-25. 2013
    ..To determine if a community-based multifactorial intervention clinic led by a nurse practitioner would improve management of First Nations people at risk of developing chronic kidney disease...
  19. doi Knowledge translation for nephrologists: strategies for improving the identification of patients with proteinuria
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Nephrol 25:933-43. 2012
    ..These considerations are relevant for dissemination and implementation of guidelines on other topics and in other clinical settings...
  20. doi Rates of treated and untreated kidney failure in older vs younger adults
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 307:2507-15. 2012
    ..Studies of kidney failure in older adults have focused on receipt of dialysis, which may underestimate the burden of disease if older people are less likely to receive treatment...
  21. pmc Design and implementation of the Canadian Kidney Disease Cohort Study (CKDCS): A prospective observational study of incident hemodialysis patients
    Aminu K Bello
    Department of Medicine, University of Alberta, Edmonton, Canada
    BMC Nephrol 12:10. 2011
    ..This study focuses on delineating potentially reversible determinants of adverse outcomes that occur in patients receiving dialysis for end-stage renal disease (ESRD)...
  22. pmc Overview of the Canadian pediatric end-stage renal disease database
    Susan M Samuel
    Division of Pediatric Nephrology, Department of Pediatrics, Alberta Children s Hospital, 2888 Shaganappi Trail NW, Calgary T3B 6A8, Canada
    BMC Nephrol 11:21. 2010
    ....
  23. pmc Authors' opinions on publication in relation to annual performance assessment
    Robin L Walker
    Department of Community Health Sciences, University of Calgary, Calgary, Canada
    BMC Med Educ 10:21. 2010
    ..Thus, the purpose of this study was to survey corresponding authors in published medical journals to determine their opinion on publication impact in relation to performance review and promotion...
  24. pmc Documentation of preventive screening interventions by general practitioners: a retrospective chart audit
    Emmanuel Ngwakongnwi
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    BMC Fam Pract 11:21. 2010
    ..This study assessed the extent to which general practitioners documented recommended preventive screening interventions among eligible patients...
  25. doi Prevention of dialysis catheter malfunction with recombinant tissue plasminogen activator
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta
    N Engl J Med 364:303-12. 2011
    ....
  26. doi Nephrology visits and health care resource use before and after reporting estimated glomerular filtration rate
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 303:1151-8. 2010
    ..Laboratory reporting of estimated glomerular filtration rate (GFR) has been widely implemented, with limited evaluation...
  27. doi Relation between kidney function, proteinuria, and adverse outcomes
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 303:423-9. 2010
    ..Although proteinuria is also associated with adverse outcomes, it is not used to refine risk estimates of adverse events in this current system...
  28. pmc Overview of the Alberta Kidney Disease Network
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 10:30. 2009
    ..The Alberta Kidney Disease Network is a collaborative nephrology research organization based on a central repository of laboratory and administrative data from the Canadian province of Alberta...
  29. doi Hospitalization for uncomplicated hypertension: an ambulatory care sensitive condition
    Robin L Walker
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 29:1462-9. 2013
    ..This study explored hospitalization rates for 1 ACSC, uncomplicated hypertension, and the factors associated with hospitalization...
  30. pmc Access to health care among status Aboriginal people with chronic kidney disease
    Song Gao
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, AB
    CMAJ 179:1007-12. 2008
    ..We determined whether access to care differed between status Aboriginal people (Aboriginal people registered under the federal Indian Act) and non-Aboriginal people with chronic kidney disease...
  31. doi Primary care physician visits by patients with incident hypertension
    Fiona M Clement
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada Institute of Public Health, University of Calgary, Calgary, Alberta, Canada Electronic address
    Can J Cardiol 30:653-60. 2014
    ..Access to a primary care physician (PCP) improves health outcomes among patients with hypertension. The study objective was to compare PCP use among patients with incident hypertension with and without comorbidities...
  32. doi Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Canada
    Circulation 123:409-16. 2011
    ..Acute kidney injury (AKI) is associated with early mortality after percutaneous coronary revascularization procedures, but its prognostic relevance to long-term clinical outcomes remains controversial...
  33. pmc Quality of care for First Nations and non-First Nations People with diabetes
    Vinay Deved
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Clin J Am Soc Nephrol 8:1188-94. 2013
    ..This study examined First Nations and non-First Nations People with diabetes for differences in quality indicators and their association with kidney failure and death...
  34. doi Change in the estimated glomerular filtration rate over time and risk of all-cause mortality
    Tanvir C Turin
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 83:684-91. 2013
    ..Thus, both declining and increasing eGFR were independently associated with mortality and underscore the importance of identifying change in eGFR over time to improve mortality risk prediction...
  35. doi Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, AB, Canada
    Lancet 376:2096-103. 2010
    ..We aimed to investigate how eGFR and proteinuria jointly modified the risks of acute kidney injury and subsequent adverse clinical outcomes...
  36. doi Outcomes among 3.5 million newly diagnosed hypertensive Canadians
    Hude Quan
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 29:592-7. 2013
    ..This population-based study assessed rates of all-cause mortality, myocardial infarction, heart failure, and stroke for up to 12 years of follow-up in 3.5 million Canadian adults newly diagnosed with hypertension...
  37. doi Validating a case definition for chronic kidney disease using administrative data
    Paul E Ronksley
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Nephrol Dial Transplant 27:1826-31. 2012
    ..The purpose of this study was to determine the validity of an algorithm derived from administrative data for identifying chronic kidney disease (CKD) compared to the reference standard of estimated glomerular filtration rate (eGFR)...
  38. doi Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study
    Marcello Tonelli
    Department of Medicine, University of Alberta, Edmonton, Canada
    Lancet 380:807-14. 2012
    ..We assessed whether chronic kidney disease should be regarded as a coronary heart disease risk equivalent...
  39. doi Higher estimated glomerular filtration rates may be associated with increased risk of adverse outcomes, especially with concomitant proteinuria
    Marcello Tonelli
    Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada
    Kidney Int 80:1306-14. 2011
    ..We do not know, however, whether the finding at higher eGFR could be due to inadequacies of the eGFR formula at low serum creatinine levels...
  40. ncbi Concentration of heparin-locking solution and risk of central venous hemodialysis catheter malfunction
    Chandra M Thomas
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, Alberta, Canada
    ASAIO J 53:485-8. 2007
    ..The association between heparin concentration and rt-PA use requires further study...
  41. pmc Nocturnal hypoxia and loss of kidney function
    Sofia B Ahmed
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 6:e19029. 2011
    ..Although obstructive sleep apnea (OSA) is more common in patients with kidney disease, whether nocturnal hypoxia affects kidney function is unknown...
  42. doi CKD and risk of hospitalization and death with pneumonia
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 54:24-32. 2009
    ..The objective of this study is to determine the associations between estimated glomerular filtration rate (eGFR) and hospitalization or death with pneumonia...
  43. doi Association of a change in erythropoiesis-stimulating agent dose during hospitalization and subsequent hemoglobin levels and transfusions in hemodialysis patients
    Ben C Wong
    University of Calgary, Calgary, Canada
    Am J Kidney Dis 62:947-52. 2013
    ..We sought to determine whether increases in ESA dose during hospital admission were associated with changes in transfusion requirement and risk of exceeding recommended hemoglobin targets...
  44. doi Contrast-induced acute kidney injury and risk of adverse clinical outcomes after coronary angiography: a systematic review and meta-analysis
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Circ Cardiovasc Interv 6:37-43. 2013
    ..We performed a systematic review and meta-analysis to characterize the associations between CI-AKI and subsequent clinical outcomes...
  45. doi Incidence, cardiovascular complications and mortality of hypertension by sex and ethnicity
    Hude Quan
    Department of Community Health Sciences, University of Calgary, 3280 Hospital Dr NW, Calgary, Alberta, Canada T2N 4Z6
    Heart 99:715-21. 2013
    ..To compare ethnic and sex difference in the incidence of newly diagnosed hypertension, and subsequent risk of cardiovascular disease outcomes among South Asian, Chinese and white patients...
  46. pmc Association between routine and standardized blood pressure measurements and left ventricular hypertrophy among patients on hemodialysis
    Jaspreet Khangura
    Department of Medicine, University of British Columbia, Vancouver, Canada
    BMC Nephrol 11:13. 2010
    ..We sought to determine agreement between various blood pressure measurement methods, as well as identify which method was the strongest correlate of LV hypertrophy among patients on hemodialysis...
  47. doi Short-term change in kidney function and risk of end-stage renal disease
    Tanvir Chowdhury Turin
    Foothills Medical Centre, Calgary, Alberta, Canada
    Nephrol Dial Transplant 27:3835-43. 2012
    ..It is unclear what degree of change in the eGFR over a 1-year period indicates clinically significant progression, and whether this change adds additional information beyond that obtained by a single eGFR measure alone...
  48. doi Validation of a case definition to define hypertension using administrative data
    Hude Quan
    Department of Community Health Sciences, University of Calgary, 3330 Hospital Dr NW, Calgary, Alberta T2N 4N1, Canada
    Hypertension 54:1423-8. 2009
    ..These results provide evidence that administrative data can be used as a relatively valid source of data to define cases of hypertension for surveillance and research purposes...
  49. pmc Dialysis and transplantation among Aboriginal children with kidney failure
    Susan M Samuel
    Department of Pediatrics, University of Calgary, Calgary, Alta
    CMAJ 183:E665-72. 2011
    ..We evaluated differences in dialysis modality, time spent on dialysis, rates of kidney transplantation, and patient and allograft survival between Aboriginal children and non-Aboriginal children...
  50. ncbi NSAID use and progression of chronic kidney disease
    Katherine Gooch
    Institute of Health Economics, Edmonton, Alberta, Canada
    Am J Med 120:280.e1-7. 2007
    ..Due to the high prevalence of both CKD and NSAID use in older adults, we sought to determine the association between NSAID use and the progression of CKD in an elderly community-based cohort...
  51. ncbi Impact of anemia on hospitalization and mortality in older adults
    Bruce F Culleton
    Department of Medicine, University of Calgary, Foothills Hospital, Rm C210, 1403 29th St NW, Calgary, AB, Canada T2N 2T9
    Blood 107:3841-6. 2006
    ..Consideration should be given to redefine "normal" hemoglobin values in the elderly. Clinical trials are also necessary to determine whether anemia correction improves quality or quantity of life in this population...
  52. pmc The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part I - blood pressure measurement, diagnosis and assessment of risk
    Robert R Quinn
    Division of Nephrology, University of Calgary, Alberta
    Can J Cardiol 26:241-8. 2010
    ..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension...
  53. pmc Excessive daytime sleepiness is associated with increased health care utilization among patients referred for assessment of OSA
    Paul E Ronksley
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary, Calgary, Canada
    Sleep 34:363-70. 2011
    ..The objective of this study was to determine if excessive daytime sleepiness was independently associated with increased health care utilization among patients referred for assessment of OSA...
  54. pmc Lifetime risk of ESRD
    Tanvir Chowdhury Turin
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Am Soc Nephrol 23:1569-78. 2012
    ..These population-based estimates may assist individuals who make decisions regarding public health policy...
  55. doi Long-term risk projection and its application to nephrology research
    Tanvir Chowdhury Turin
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Nephrol 25:441-9. 2012
    ..Although short-term risks are important, long-term risk can be particularly beneficial for future prediction of the burden of kidney disease, and to assist in health planning and public education...
  56. ncbi Prevalence of chronic kidney disease and survival among aboriginal people
    Song Gao
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, Alberta, Canada
    J Am Soc Nephrol 18:2953-9. 2007
    ....
  57. doi Quality of care and mortality are worse in chronic kidney disease patients living in remote areas
    Diana Rucker
    Department of Medicine, University of Alberta, Alberta, Canada
    Kidney Int 79:210-7. 2011
    ....
  58. pmc Association between chronic conditions and perceived unmet health care needs
    Paul E Ronksley
    Department of Community Health Sciences at the University of Calgary, Calgary, Alberta, Canada
    Open Med 6:e48-58. 2012
    ..The objective of this study was therefore to determine the association between chronic conditions and perceived unmet health care needs...
  59. pmc Association of enrolment in primary care networks with diabetes care and outcomes among First Nations and low-income Albertans
    David J T Campbell
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Open Med 6:e155-65. 2012
    ..However, it is unknown whether First Nations individuals and those in lower SES groups experience these benefits...
  60. doi One-year change in kidney function is associated with an increased mortality risk
    Tanvir Chowdhury Turin
    Department of Medicine, University of Calgary, AB, Canada
    Am J Nephrol 36:41-9. 2012
    ..Long-term cohort studies report that death is a likelier outcome than progression to kidney failure. However, it is unclear how short-term changes in estimated GFR (eGFR) over a 1-year period relate to subsequent mortality risk...
  61. pmc Clinical presentation of obstructive sleep apnea in patients with chronic kidney disease
    David D M Nicholl
    Department of Medicine, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Clin Sleep Med 8:381-7. 2012
    ..Obstructive sleep apnea (OSA) is an important and common comorbidity in patients with chronic kidney disease (CKD). However, few studies have addressed how OSA presents in this patient population and whether it is clinically apparent...
  62. doi Declining kidney function increases the prevalence of sleep apnea and nocturnal hypoxia
    David D M Nicholl
    Department of Medicine, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada
    Chest 141:1422-30. 2012
    ..We sought to determine the prevalence of sleep apnea and associated nocturnal hypoxia in patients with CKD and ESRD. We hypothesized that the prevalence of sleep apnea would increase progressively as kidney function declines...
  63. doi Association between GFR, proteinuria, and adverse outcomes among White, Chinese, and South Asian individuals in Canada
    Joslyn Conley
    Department of Medicine, University of Calgary, Alberta, Canada
    Am J Kidney Dis 59:390-9. 2012
    ..We investigated the association between proteinuria, estimated glomerular filtration rate (eGFR), and risk of mortality and kidney failure in white, Chinese, and South Asian populations...
  64. pmc Cardiovascular effects of angiotensin converting enzyme inhibition or angiotensin receptor blockade in hemodialysis: a meta-analysis
    Davina J Tai
    Division of Nephrology, Foothills Medical Centre, 1403 29th Street NW, Calgary, Alberta, Canada, T2N 2T9
    Clin J Am Soc Nephrol 5:623-30. 2010
    ..This meta-analysis was performed to determine whether angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) reduce fatal and nonfatal CV events and left ventricular (LV) mass in patients receiving HD...
  65. doi Acute kidney injury following coronary angiography is associated with a long-term decline in kidney function
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 78:803-9. 2010
    ..8 ml/min following moderate to severe acute kidney injury. Thus, acute kidney injury following coronary angiography is associated with a sustained loss and a larger rate of future decline in kidney function...
  66. ncbi Differences in use of peritoneal dialysis and survival among East Asian, Indo Asian, and white ESRD patients in Canada
    Brenda R Hemmelgarn
    Department of Medicine, Division of Nephrology, University of Calgary, Canada
    Am J Kidney Dis 48:964-71. 2006
    ..Racial differences in health outcomes in general are well documented; however, few studies examined the impact of East Asian and Indo Asian race on choice of dialytic modality and survival among patients with end-stage renal disease (ESRD)...
  67. doi Canadian provincial trends in antihypertensive drug prescriptions between 1996 and 2006
    Robin L Walker
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 27:461-7. 2011
    ..Little is known regarding potential differences in antihypertensive prescribing practices at a Canadian provincial level. Our objective was to determine provincial differences in the use of antihypertensive drug therapy in Canada...
  68. doi Hemodialysis prescription education decreases intradialytic hypotension
    Davina J Tai
    Department of Medicine, University of Calgary, Calgary, Alberta Canada and Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Nephrol 26:315-22. 2013
    ..Intradialytic hypotension (IDH) is associated with increased morbidity and mortality. We studied the impact of an education program and hemodialysis (HD) prescription optimization on the frequency of IDH...
  69. pmc Renal outcomes associated with invasive versus conservative management of acute coronary syndrome: propensity matched cohort study
    Matthew T James
    Department of Medicine, University of Calgary, Foothills Medical Centre, 1403 29th St NW, Calgary, Alberta T2N 2T9, Canada
    BMJ 347:f4151. 2013
    ....
  70. doi Chronic kidney disease and life expectancy
    Tanvir Chowdhury Turin
    Department of Medicine, University of Calgary, Calgary, Canada
    Nephrol Dial Transplant 27:3182-6. 2012
    ..Life expectancy is commonly used as an indicator of health and reflects disease burden in the population. The life expectancy for patients with lower levels of kidney function has not been reported...
  71. pmc Validation of a case definition to define chronic dialysis using outpatient administrative data
    Fiona M Clement
    Department of Medicine, University of Calgary, 2500 University Dr NW, Calgary, Alberta, T2N 1N4, Canada
    BMC Med Res Methodol 11:25. 2011
    ..The objective of this study is to determine the validity of outpatient physician billing derived algorithms for defining chronic dialysis compared to a reference standard ESRD registry...
  72. pmc Prevention of catheter lumen occlusion with rT-PA versus heparin (Pre-CLOT): study protocol of a randomized trial [ISRCTN35253449]
    Brenda R Hemmelgarn
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 7:8. 2006
    ..The Prevention of Catheter Lumen Occlusion with rt-PA versus Heparin (PreCLOT) study will determine if use of weekly rt-PA, compared to regular heparin, as a catheter locking solution, will decrease the risk of catheter malfunction...
  73. doi Risk of bloodstream infection in patients with chronic kidney disease not treated with dialysis
    Matthew T James
    Department of Medicine, University of Calgary, Foothills Medical Center, 1403 29th St NW, Calgary, AB T2N 2T9, Canada
    Arch Intern Med 168:2333-9. 2008
    ..Whether patients with chronic kidney disease who are not receiving dialysis are also at increased risk of bloodstream infection is less clear...
  74. ncbi Association between multidisciplinary care and survival for elderly patients with chronic kidney disease
    Brenda R Hemmelgarn
    Department of Medicine, Community Health Schiences, University of Calgary, Calgary, Canada
    J Am Soc Nephrol 18:993-9. 2007
    ..The benefits of MDC and an assessment of their economic impact should be tested in a randomized, controlled trial...
  75. pmc A novel technique to optimize facility locations of new nephrology services for remote areas
    Bharati Ayyalasomayajula
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Clin J Am Soc Nephrol 6:2157-64. 2011
    ....
  76. doi The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy
    Doreen M Rabi
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 27:415-433.e1-2. 2011
    ..We also discussed the recent analyses that examined the association between angiotensin II receptor blockers (ARBs) and cancer...
  77. pmc Factors associated with initiation of chronic renal replacement therapy for patients with kidney failure
    Labib I Faruque
    Department of Medicine, University of Alberta, Edmonton, AB, Canada
    Clin J Am Soc Nephrol 8:1327-35. 2013
    ..Patients with kidney failure sometimes do not receive chronic renal replacement therapy (RRT), even though this may reduce their life expectancy. This study aimed to identify factors associated with initiation of chronic RRT...
  78. doi Relationship between primary care physician visits and hospital/emergency use for uncomplicated hypertension, an ambulatory care-sensitive condition
    Robin L Walker
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 30:1640-8. 2014
    ..The purpose of this study was to examine the association between one ACSC, uncomplicated hypertension, and previous primary care physician (PCP) utilization...
  79. pmc The impact of nocturnal hemodialysis on sexual function
    Adam Bass
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 13:67. 2012
    ..We compared sexual activity and responses to sexual related questions in the Kidney Disease Quality of Life Short Form questionnaire among patients randomized to frequent nocturnal or thrice weekly conventional hemodialysis...
  80. pmc Estimated GFR and fracture risk: a population-based study
    Meghan J Elliott
    Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Clin J Am Soc Nephrol 8:1367-76. 2013
    ..This study sought to determine the association between estimated GFR (eGFR) and fracture rates...
  81. pmc The prevalence of restless legs syndrome across the full spectrum of kidney disease
    Jonathan Lee
    Department of Medicine, Faculty of Medicine, University of Calgary, Calgary, AB, Canada
    J Clin Sleep Med 9:455-9. 2013
    ..The objectives of the study were to determine the prevalence of RLS across the full spectrum of kidney disease and to assess the impact of RLS on sleep quality and daytime function...
  82. ncbi The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of risk
    Brenda R Hemmelgarn
    Division of Nephrology, University of Calgary, Calgary, Canada
    Can J Cardiol 21:645-56. 2005
    ..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with high blood pressure (BP)...
  83. pmc Incidence and causes of end-stage renal disease among Aboriginal children and young adults
    Susan M Samuel
    Division of Pediatric Nephrology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada
    CMAJ 184:E758-64. 2012
    ..Although Aboriginal adults have a higher risk of end-stage renal disease than non-Aboriginal adults, the incidence and causes of end-stage renal disease among Aboriginal children and young adults are not well described...
  84. pmc Adding specialized clinics for remote-dwellers with chronic kidney disease: a cost-utility analysis
    Natasha Wiebe
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Clin J Am Soc Nephrol 7:24-34. 2012
    ..This study aimed to determine whether opening a new clinic in a remote region would be a cost-effective means of improving care for remote-dwellers with CKD...
  85. ncbi Survival after coronary revascularization among patients with kidney disease
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Circulation 110:1890-5. 2004
    ..3 mg/dl)...
  86. doi Graft failure and adaptation period to adult healthcare centers in pediatric renal transplant patients
    Susan M Samuel
    Alberta Children s Hospital, Calgary, Alberta, Canada
    Transplantation 91:1380-5. 2011
    ..Transfer from pediatric to adult care may require a period of adaptation to the new healthcare environment. We sought to determine whether this adaptation period was associated with an increased risk of graft failure...
  87. ncbi Refined characterization of the association between kidney function and mortality in patients undergoing cardiac catheterization
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Eur Heart J 27:1191-7. 2006
    ....
  88. doi Spatial analysis to locate new clinics for diabetic kidney patients in the underserved communities in Alberta
    Labib Imran Faruque
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Nephrol Dial Transplant 27:4102-9. 2012
    ..Canadians with chronic diseases often live far away from healthcare facilities, which may compromise their level of care. We used a new method for selecting optimal locations for new healthcare facilities in remote regions...
  89. pmc Diagnostic value of screening instruments for identifying obstructive sleep apnea in kidney failure
    David D M Nicholl
    Department of Medicine, University of Calgary, Alberta, Canada
    J Clin Sleep Med 9:31-8. 2013
    ..The Berlin Questionnaire (BQ), Adjusted Neck Circumference (ANC), and STOP-BANG questionnaire are 3 such instruments that have been validated in patients with normal kidney function...
  90. pmc Enrolment in primary care networks: impact on outcomes and processes of care for patients with diabetes
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alta
    CMAJ 184:E144-52. 2012
    ..We sought to determine the association between enrolment in primary care networks and the care and outcomes of patients with diabetes...
  91. pmc Evaluation of an electronic warfarin nomogram for anticoagulation of hemodialysis patients
    Benjamin K A Thomson
    Department of Medicine, University of Calgary, Calgary, Alberta Canada
    BMC Nephrol 12:46. 2011
    ..We evaluated the effectiveness of anticoagulation using an electronic warfarin nomogram administered by nurses in outpatient hemodialysis patients, compared to physician directed therapy...
  92. ncbi Meta-analysis: antibiotics for prophylaxis against hemodialysis catheter-related infections
    Matthew T James
    University of Calgary, Calgary, and University of Alberta and Institute of Health Economics, Edmonton, Alberta, Canada
    Ann Intern Med 148:596-605. 2008
    ..Catheter-related infections cause morbidity and mortality in patients undergoing hemodialysis...
  93. doi Ascorbic acid for anemia management in hemodialysis patients: a systematic review and meta-analysis
    Vinay Deved
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 54:1089-97. 2009
    ..Ascorbic acid is believed to improve anemia in patients with end-stage renal disease, but its overall effectiveness is unclear...
  94. doi The effect of nocturnal and conventional hemodialysis on markers of nutritional status: results from a randomized trial
    Melissa Schorr
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Ren Nutr 21:271-6. 2011
    ..More frequent dialysis may improve nutrition and remove dietary restrictions in hemodialysis (HD) patients. We present results from a trial comparing nutritional parameters between nocturnal hemodialysis (NHD) and conventional HD patients...
  95. pmc Effect of fish oil supplementation on graft patency and cardiovascular events among patients with new synthetic arteriovenous hemodialysis grafts: a randomized controlled trial
    Charmaine E Lok
    University of Toronto, and Division of Nephrology, Department of Medicine, Toronto General Hospital, 8NU 844, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada
    JAMA 307:1809-16. 2012
    ..Synthetic arteriovenous grafts, an important option for hemodialysis vascular access, are prone to recurrent stenosis and thrombosis. Supplementation with fish oils has theoretical appeal for preventing these outcomes...
  96. ncbi Evaluation of an education intervention to increase the pursuit of living kidney donation: a randomized controlled trial
    Lianne Barnieh
    University of Calgary, Calgary, Alberta, Canada
    Prog Transplant 21:36-42. 2011
    ..Many transplant candidates have concerns about living donation...
  97. doi Modification of outcomes after acute kidney injury by the presence of CKD
    Neesh Pannu
    Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, Canada
    Am J Kidney Dis 58:206-13. 2011
    ..Acute kidney injury (AKI) in hospitalized patients is associated with poor outcomes; however, it is unclear how relationships between AKI and clinical outcomes vary with baseline kidney function...
  98. pmc Trends in antihypertensive drug prescriptions and physician visits in Canada between 1996 and 2006
    Brenda R Hemmelgarn
    Department of Community of Health Sciences, University of Calgary, Calgary, Alberta
    Can J Cardiol 24:507-12. 2008
    ..In 1999, the Canadian Hypertension Education Program (CHEP) was launched to develop and implement evidence-based hypertension guidelines...
  99. doi Oral estrogen therapy in postmenopausal women is associated with loss of kidney function
    Sofia B Ahmed
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 74:370-6. 2008
    ..Our study shows an independent association in a dose-dependent manner of estrogen use and loss of kidney function in this elderly population...
  100. ncbi Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial
    Bruce F Culleton
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 298:1291-9. 2007
    ..Morbidity and mortality rates in hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes...
  101. doi Survival and transplantation outcomes of children less than 2 years of age with end-stage renal disease
    R Todd Alexander
    Department of Pediatrics, University of Alberta, Edmonton, AB, Canada
    Pediatr Nephrol 27:1975-83. 2012
    ..Young children with end-stage renal disease (ESRD) requiring renal replacement therapy (RRT) have traditionally experienced high rates of morbidity and mortality; however, detailed long-term follow-up data is limited...