Enrico Heffler



  1. Heffler E, Crimi C, Mancuso S, Campisi R, Puggioni F, Brussino L, et al. Misdiagnosis of asthma and COPD and underuse of spirometry in primary care unselected patients. Respir Med. 2018;142:48-52 pubmed publisher
    ..Novel strategies to overcome this situation include should be implemented to give a better care to our patients. ..
  2. Malinovschi A, Masoero M, Bellocchia M, Ciuffreda A, Solidoro P, Mattei A, et al. Severe vitamin D deficiency is associated with frequent exacerbations and hospitalization in COPD patients. Respir Res. 2014;15:131 pubmed publisher
    ..This association was independent of patients' characteristics and comorbidities. ..
  3. Fassio F, Losappio L, Antolin Amerigo D, Peveri S, Pala G, Preziosi D, et al. Kounis syndrome: A concise review with focus on management. Eur J Intern Med. 2016;30:7-10 pubmed publisher
    ..The pathogenesis of the syndrome is discussed, and a therapeutic algorithm is proposed. ..
  4. Heffler E, Sberna M, Sichili S, Intravaia R, Nicolosi G, Porto M, et al. High prevalence of Anisakis simplex hypersensitivity and allergy in Sicily, Italy. Ann Allergy Asthma Immunol. 2016;116:146-50 pubmed publisher
  5. Heffler E, Crimi C, Campisi R, Sichili S, Nicolosi G, Porto M, et al. Bronchodilator response as a marker of poor asthma control. Respir Med. 2016;112:45-50 pubmed publisher
    ..Bronchodilator response, correlating with worse asthma control even in patients with normal spirometry, should be test at every visit as it may add information on asthma control. ..
  6. Heffler E, Allegra A, Pioggia G, Picardi G, Musolino C, Gangemi S. MicroRnas Profiling in Asthma: Potential Biomarkers and Therapeutic Targets. Am J Respir Cell Mol Biol. 2017;: pubmed publisher
  7. Heffler E, Terranova G, Chessari C, Frazzetto V, Crimi C, Fichera S, et al. Point-of-care blood eosinophil count in a severe asthma clinic setting. Ann Allergy Asthma Immunol. 2017;119:16-20 pubmed publisher
    ..The results of our study contribute to the validation of a point-of-care device to assess blood eosinophils and open the possibility of using this device for the management of severe asthma management. ..