Gulen Hatemi

Summary

Publications

  1. ncbi request reprint Behçet's syndrome: a critical digest of the recent literature
    G Hatemi
    Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Turkey
    Clin Exp Rheumatol 30:S80-9. 2012
  2. ncbi request reprint Currently Used Biologic Agents in the Management of Behcet's Syndrome
    Caner Saygin
    Cerrahpasa Tip Fakultesi, Ic Hastaliklari Anabilim Dali, Romatoloji Bilim Dali, 34089, Cerrahpasa, Istanbul, Turkey
    Curr Med Chem 22:1976-85. 2015
  3. ncbi request reprint Behçet's syndrome: a critical digest of the 2013-2014 literature
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Clin Exp Rheumatol 32:S112-22. 2014
  4. doi request reprint No appreciable decrease in fertility in Behçet's syndrome
    Didem Uzunaslan
    Cerrahpasa Tip Fakultesi, Ic Hastaliklari Anabilim Dali, Romatoloji Bilim Dali, Fatih, Istanbul 34098, Turkey
    Rheumatology (Oxford) 53:828-33. 2014
  5. ncbi request reprint Behçet's syndrome: a critical digest of the 2012-2013 literature
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Clin Exp Rheumatol 31:108-17. 2013
  6. doi request reprint Behçet's syndrome and micro-organisms
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Best Pract Res Clin Rheumatol 25:389-406. 2011
  7. doi request reprint Pulmonary artery involvement in Behçet׳s syndrome: Effects of anti-Tnf treatment
    Vedat Hamuryudan
    Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Fatih, Istanbul, Turkey Electronic address
    Semin Arthritis Rheum 45:369-73. 2015
  8. doi request reprint Colchicine in Behçet syndrome: a longterm survey of patients in a controlled trial
    Vedat Hamuryudan
    From the Behçet s Syndrome Research Center, Istanbul University, Istanbul, Turkey
    J Rheumatol 41:735-8. 2014
  9. doi request reprint Analyses of functional IL10 and TNF-α genotypes in Behçet's syndrome
    Omer Ates
    Department of Molecular Biology and Genetics, Science Faculty, Istanbul University, Istanbul, Turkey
    Mol Biol Rep 37:3637-41. 2010
  10. doi request reprint Prognosis of Behcet's syndrome among men with mucocutaneous involvement at disease onset: long-term outcome of patients enrolled in a controlled trial
    Vedat Hamuryudan
    Department of Internal Medicine, Division of Rheumatology, Cerrahpasa Medical School, Istanbul University, Aksaray, 34365, Istanbul, Turkey
    Rheumatology (Oxford) 49:173-7. 2010

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Behçet's syndrome: a critical digest of the recent literature
    G Hatemi
    Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Turkey
    Clin Exp Rheumatol 30:S80-9. 2012
    ..Switching between anti-TNF agents, when needed, is possible. Interleukin-1 and interleukin-6 are new promising targets...
  2. ncbi request reprint Currently Used Biologic Agents in the Management of Behcet's Syndrome
    Caner Saygin
    Cerrahpasa Tip Fakultesi, Ic Hastaliklari Anabilim Dali, Romatoloji Bilim Dali, 34089, Cerrahpasa, Istanbul, Turkey
    Curr Med Chem 22:1976-85. 2015
    ..In this review, we discuss the efficacy and safety of various recently developed biologic agents targeting different pathways involved in the pathogenesis of BS. ..
  3. ncbi request reprint Behçet's syndrome: a critical digest of the 2013-2014 literature
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Clin Exp Rheumatol 32:S112-22. 2014
    ....
  4. doi request reprint No appreciable decrease in fertility in Behçet's syndrome
    Didem Uzunaslan
    Cerrahpasa Tip Fakultesi, Ic Hastaliklari Anabilim Dali, Romatoloji Bilim Dali, Fatih, Istanbul 34098, Turkey
    Rheumatology (Oxford) 53:828-33. 2014
    ..Behçet's syndrome (BS) follows an active course during the childbearing years in both men and women. We formally surveyed the infertility rate and the effect of drugs and types of organ involvement on fertility in BS...
  5. ncbi request reprint Behçet's syndrome: a critical digest of the 2012-2013 literature
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Clin Exp Rheumatol 31:108-17. 2013
    ..Switching to another biologic can be effective when the first or even the second biologic agent fails or is stopped due to adverse events. ..
  6. doi request reprint Behçet's syndrome and micro-organisms
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Best Pract Res Clin Rheumatol 25:389-406. 2011
    ..Moreover, basic research on both viruses and bacteria suggests that micro-organisms may be playing a role, possibly through heat shock proteins and T-cell hypersensitivity...
  7. doi request reprint Pulmonary artery involvement in Behçet׳s syndrome: Effects of anti-Tnf treatment
    Vedat Hamuryudan
    Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Fatih, Istanbul, Turkey Electronic address
    Semin Arthritis Rheum 45:369-73. 2015
    ..Anti-TNF agents are being increasingly used in patients with Behçet׳s syndrome (BS) when conventional immunosuppressives fail. However, experience with anti-TNF treatment on pulmonary artery involvement (PAI) of BS is limited...
  8. doi request reprint Colchicine in Behçet syndrome: a longterm survey of patients in a controlled trial
    Vedat Hamuryudan
    From the Behçet s Syndrome Research Center, Istanbul University, Istanbul, Turkey
    J Rheumatol 41:735-8. 2014
    ..To test the hypothesis that colchicine use during early disease decreases immunosuppressive use in Behçet syndrome (BS) in the long term...
  9. doi request reprint Analyses of functional IL10 and TNF-α genotypes in Behçet's syndrome
    Omer Ates
    Department of Molecular Biology and Genetics, Science Faculty, Istanbul University, Istanbul, Turkey
    Mol Biol Rep 37:3637-41. 2010
    ..Our study indicates that functional TNF-α, IL10 genotypes or combined TNF-α, IL10 genotypes do not play a role in BS susceptibility in Turkish BS patients...
  10. doi request reprint Prognosis of Behcet's syndrome among men with mucocutaneous involvement at disease onset: long-term outcome of patients enrolled in a controlled trial
    Vedat Hamuryudan
    Department of Internal Medicine, Division of Rheumatology, Cerrahpasa Medical School, Istanbul University, Aksaray, 34365, Istanbul, Turkey
    Rheumatology (Oxford) 49:173-7. 2010
    ..To assess the influence of being free of major organ involvement during the early years of the disease on the prognosis of men with Behçet's syndrome (BS)...
  11. doi request reprint Pulmonary artery involvement and associated lung disease in Behçet disease: a series of 47 patients
    Emire Seyahi
    Division of Rheumatology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
    Medicine (Baltimore) 91:35-48. 2012
    ..Corticosteroids and immunosuppressive agents are the mainstays of treatment; however, refractory cases may require embolization, lobectomy, cavitectomy, and decortication...
  12. doi request reprint The papulopustular lesion/arthritis cluster of Behçet's syndrome also clusters in families
    Mehmet Karaca
    Behçet s Syndrome Research Center, Cerrahpasa Medical School, Istanbul University, Turkey
    Rheumatology (Oxford) 51:1053-60. 2012
    ..To test this hypothesis, we compared the frequency of symptom clusters between familial (group F) and non-familial (group NF) cases of BS...
  13. doi request reprint Current Status, Goals, and Research Agenda for Outcome Measures Development in Behçet Syndrome: Report from OMERACT 2014
    Gulen Hatemi
    From the Division of Rheumatology, Department of Internal Medicine, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey Department of Internal Medicine, University Paris Diderot, Paris, France Division of Rheumatology, Koc University Faculty of Medicine, Istanbul Faculty of Health Sciences, Marmara University Department of Psychology, Istanbul University, Istanbul, Turkey Celgene Corporation, Warren, New Jersey Rutgers, Robert Wood Johnson Medical School, Department of Rheumatology, New Brunswick, New Jersey Division of Rheumatology and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA G Hatemi, MD, Associate Professor of Medicine, Division of Rheumatology, Department of Internal Medicine, Istanbul University Cerrahpasa Faculty of Medicine Y Ozguler, MD, Fellow in Rheumatology, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine H Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine A Mahr, MD, PhD, Professor of Internal Medicine, Department of Internal Medicine, Germany
    J Rheumatol 42:2436-41. 2015
    ..0, and discussions during the first meeting of the BS working group held during OMERACT 12 (2014)...
  14. ncbi request reprint A reappraisal of the association between Behçet's disease, myelodysplastic syndrome and the presence of trisomy 8: a systematic literature review
    Sinem Nihal Esatoglu
    Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey
    Clin Exp Rheumatol 33:S145-51. 2015
    ....
  15. doi request reprint Atherosclerosis in Behçet's Syndrome
    Emire Seyahi
    Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
    Semin Arthritis Rheum 38:1-12. 2008
    ..Thus, we evaluated the presence of subclinical atherosclerosis in a sizeable group of patients with BS both with major organ involvement and mucocutaneous disease along with diseased and healthy controls...
  16. doi request reprint Behçet's syndrome
    Gulen Hatemi
    Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Cerrahpasa, Istanbul 34089, Turkey
    Rheum Dis Clin North Am 39:245-61. 2013
    ..Being a serious health problem in endemic areas, BS also attracts global attention as a model to study inflammatory diseases of unknown cause...
  17. doi request reprint Tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphisms in Turkish rheumatoid arthritis patients
    Omer Ates
    Department of Molecular Biology and Genetics, Science Faculty, Istanbul University, 34118 Vezneciler, Istanbul, Turkey
    Clin Rheumatol 27:1243-8. 2008
    ..Our findings suggest that IL-10 1082 G/A polymorphism or GCC, ACC haplotypes may be associated with RA in Turkish patients...
  18. ncbi request reprint Should immunosuppressives be stopped in granulomatosis with polyangiitis (Wegener's granulomatosis) patients undergoing dialysis?
    Deram Buyuktas
    Department of Internal Medicine, Cerrahpasa Medical School, University of Istanbul, Turkey
    Clin Exp Rheumatol 30:S104-6. 2012
    ..The decision to stop immunosuppressives while starting dialysis should be made on an individual basis in patients with GPA, and the risks and benefits should be carefully evaluated...
  19. ncbi request reprint Behçet's syndrome: a critical digest of the 2014-2015 literature
    Gulen Hatemi
    Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Turkey
    Clin Exp Rheumatol 33:S3-14. 2015
    ..Adalimumab seems to be effective in severe uveitis of BS even after failure of infliximab. New cytokine inhibitors targeting IL-1 and IL-6 appear to be effective especially for uveitis and CNS involvement refractory to anti TNF agents. ..
  20. ncbi request reprint Fatigue is correlated with disease activity but not with the type of organ involvement in Behçet's syndrome: a comparative clinical survey
    Deram Buyuktas
    Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey and Georg August University, University Medical Center Gottingen, Department of Hematology Oncology, Gottingen, Germany
    Clin Exp Rheumatol 33:S107-12. 2015
    ..We aimed to evaluate the severity and impact of fatigue in Behçet's syndrome (BS) and to determine its association with type of organ involvement and gender...
  21. pmc Quantiferon-TB Gold in tube assay for the screening of tuberculosis before and during treatment with tumor necrosis factor alpha antagonists
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Arthritis Res Ther 14:R147. 2012
    ....
  22. ncbi request reprint The frequency of familial Mediterranean fever in an emergency unit
    Seval Masatlioglu
    Department of Internal Medicine, Haydarpasa Haydarpasa Numune Research and Education Hospital, Istanbul, Turkey
    Clin Exp Rheumatol 29:S44-6. 2011
    ..Physicians working in emergency units should include FMF in their differential diagnosis list when evaluating a patient with acute abdominal pain, especially in countries where the disease is prevalent...
  23. doi request reprint Increased enthesopathy among Behçet's syndrome patients with acne and arthritis: an ultrasonography study
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey
    Arthritis Rheum 58:1539-45. 2008
    ..The aim of this study was to test the hypothesis that enthesopathy is increased in this cluster, having features reminiscent of acne-associated arthritis...
  24. ncbi request reprint Suicidal ideation among patients with Behçet's syndrome
    Caner Saygin
    Behçet s Syndrome Research Centre, Istanbul University, Istanbul, Turkey
    Clin Exp Rheumatol 33:S30-5. 2015
    ..To evaluate the frequency of suicidal ideation among Behçet's syndrome (BS) patients compared to healthy and diseased controls and to delineate possible factors predicting an increase in suicidal ideation...
  25. pmc Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever
    Asli K Kirectepe
    Institute of Science and Technology, Molecular Biology Genetics and Biotechnology Graduate Program, Istanbul Technical University, Istanbul, Turkey
    BMC Med Genet 12:105. 2011
    ..Here, we tested the hypothesis that the MEFV transcript level in FMF patients correlates with its methylation level, and methylation, by allowing transcription silencing, has a role in FMF ethiopathogenesis...
  26. doi request reprint Genetic susceptibility to Behçet's syndrome is associated with NRAMP1 (SLC11A1) polymorphism in Turkish patients
    Omer Ates
    Department of Molecular Biology and Genetics, Science Faculty, Istanbul University, Vezneciler, 34118, Istanbul, Turkey
    Rheumatol Int 29:787-91. 2009
    ..Our study suggests that NRAMP1 may be one of the plausible candidate genes for BS. However, it is likely that INT4 polymorphism is not disease-specific and seems to be common to immune-mediated diseases...
  27. ncbi request reprint TNF-alpha antagonists and thalidomide for the management of gastrointestinal Behçet's syndrome refractory to the conventional treatment modalities: a case series and review of the literature
    Ibrahim Hatemi
    Division of Gastroenterology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey
    Clin Exp Rheumatol 33:S129-37. 2015
    ..In this paper we report our experience on 13 patients with gastrointestinal involvement of Behçet's syndrome who were refractory to the conventional therapy and who were treated with TNF-alpha antagonists and/or thalidomide...
  28. doi request reprint Ocular Involvement of Behçet's Syndrome: a Comprehensive Review
    Yilmaz Ozyazgan
    Cerrahpasa Medical School, Department of Ophthalmology, Istanbul University, Istanbul, Turkey
    Clin Rev Allergy Immunol 49:298-306. 2015
    ..Surgery may be required in selected cases. The prognosis of eye involvement has greatly improved over the last decades with the effective use of immunosuppressives. ..
  29. ncbi request reprint Infliximab does not suppress the tuberculin skin test (purified protein derivative)
    Gulen Hatemi
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Rheumatology Division and Haydarpasa Numune Hospital, Department of Internal Medicine, Istanbul, Turkey
    J Rheumatol 34:474-80. 2007
    ..We assessed whether infliximab, a strong inhibitor of inflammation, suppressed dermal induration, the outcome of this test. We also reassessed the booster phenomenon and the interobserver variability in tuberculin testing...
  30. pmc Outcome measures used in clinical trials for Behçet syndrome: a systematic review
    Gulen Hatemi
    From the Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey Division of Rheumatology and Department of Epidemiology, University of Pennsylvania, Philadelphia, PA, USA Department of Clinical Epidemiology, VU University Medical Center, Amsterdam, the Netherlands Department of Rheumatology, Marmara University School of Medicine, Istanbul Department of Rheumatology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey
    J Rheumatol 41:599-612. 2014
    ....
  31. ncbi request reprint Increased serum sialic acid levels in primary osteoarthritis and inactive rheumatoid arthritis
    A Ata Alturfan
    Vocational School Health Services, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Tohoku J Exp Med 213:241-8. 2007
    ..These results suggest that SA may be considered as a potent defense molecule against oxidative damage in arthritis. Antioxidant therapy may halt or ameliorate the progression of arthritis...
  32. doi request reprint JAK2 (V617F) mutation is not associated with thrombosis in Behcet syndrome
    M Cem Ar
    Division of Hematology, Department of Internal Medicine, Istanbul Training and Research Hospital, Istanbul, Turkey
    Clin Appl Thromb Hemost 18:421-6. 2012
    ..Our data suggest that JAK2 (V617F) is not directly related to thrombosis in MPNs and in other thrombotic entities, such as BS...
  33. ncbi request reprint Double pylorus in a patient with Behçet's syndrome
    Ibrahim Hatemi
    Division of Gastroenterology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey
    Clin Exp Rheumatol 33:S138-40. 2015
    ..The possibility of peptic ulcer disease related to non-steroidal anti-inflammatory drug use or Behçet's syndrome itself, as the cause of this rare condition in this patient is discussed. ..
  34. doi request reprint Update on Outcome Measure Development for Large Vessel Vasculitis: Report from OMERACT 12
    Sibel Zehra Aydin
    From the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey Division of Rheumatology, University of California, Los Angeles, California, USA Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK Department of Internal Medicine, University Paris Diderot, Paris, France Division of Rheumatology, Ohio State University, Columbus, Ohio, USA Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland S Z Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine H Direskeneli, USA
    J Rheumatol 42:2465-9. 2015
    ..This report summarizes the progress that has been made on a disease activity assessment tool and patient-reported outcomes in LVV as well as the group's research agenda...
  35. doi request reprint Management of Behçet's syndrome
    Yesim Ozguler
    Department of Internal Medicine, Division of Rheumatology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey
    Curr Opin Rheumatol 28:45-50. 2016
    ..Current trends in the management of Behçet's syndrome will be reviewed in this article...
  36. doi request reprint Bone marrow transplantation for Behçet's disease: a case report and systematic review of the literature
    Teoman Soysal
    Division of Hematology, Division of Rheumatology, Division of Gastroenterology, Department of Internal Medicine and Division of Hematopathology, Department of Pathology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Rheumatology (Oxford) 53:1136-41. 2014
    ..The objectives of this study were to describe a BD patient undergoing HSCT and to evaluate the outcomes of BD patients who underwent HSCT...
  37. doi request reprint Management of Behçet's syndrome
    Yesim Ozguler
    Istanbul University, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
    Curr Opin Rheumatol 26:285-91. 2014
    ..There is agreement that the management of Behçet's syndrome has recently improved, especially with the wider use of biologics. The aim of this review is to summarize the current management strategies in Behçet's syndrome...