Cesare Hassan

Summary

Publications

  1. ncbi request reprint Performance improvements of imaging-based screening tests
    Cesare Hassan
    Nuovo Regina Margherita Hospital, Via Morosini 30, 00153 Rome, Italy
    Best Pract Res Clin Anaesthesiol 24:493-507. 2010
  2. doi request reprint Computed tomographic colonography to screen for colorectal cancer, extracolonic cancer, and aortic aneurysm: model simulation with cost-effectiveness analysis
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, and Department of Radiological Sciences, University Polo Pontino, Rome, Italy
    Arch Intern Med 168:696-705. 2008
  3. doi request reprint Cost effectiveness of colonoscopy, based on the appropriateness of an indication
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Clin Gastroenterol Hepatol 6:1231-6. 2008
  4. ncbi request reprint Appropriateness of the indication for colonoscopy: systematic review and meta-analysis
    Cesare Hassan
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italia
    J Gastrointestin Liver Dis 20:279-86. 2011
  5. pmc New paradigms for colonoscopic management of diminutive colorectal polyps: predict, resect, and discard or do not resect?
    Cesare Hassan
    Digestive Endoscopy Unit, Istituto Clinico Humanitas, Milan, Italy
    Clin Endosc 46:130-7. 2013
  6. pmc Computed tomographic colonography for colorectal cancer screening: risk factors for the detection of advanced neoplasia
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Cancer 119:2549-54. 2013
  7. ncbi request reprint Colonic polyps: are we ready to resect and discard?
    Cesare Hassan
    Digestive Endoscopy Unit, IRCCS Istituto Clinico Humanitas, Via Manzoni 56, Rozzano, Milan 20089, Italy
    Gastrointest Endosc Clin N Am 23:663-78. 2013
  8. doi request reprint Management of subcentimetric polyps detected by CT colonography
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Via Morosini 30, 00153 Rome, Italy
    Nat Rev Gastroenterol Hepatol 10:119-24. 2013
  9. doi request reprint Meta-analysis: adherence to colorectal cancer screening and the detection rate for advanced neoplasia, according to the type of screening test
    C Hassan
    Laziosanita Agenzia di sanita pubblica, Regione Lazio, Rome, Italy
    Aliment Pharmacol Ther 36:929-40. 2012
  10. doi request reprint Cost-effectiveness of CT colonography
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Roma 00153, Italy
    Radiol Clin North Am 51:89-97. 2013

Collaborators

Detail Information

Publications96

  1. ncbi request reprint Performance improvements of imaging-based screening tests
    Cesare Hassan
    Nuovo Regina Margherita Hospital, Via Morosini 30, 00153 Rome, Italy
    Best Pract Res Clin Anaesthesiol 24:493-507. 2010
    ..Colon capsule endoscopy appears to be a safe and technically feasible procedure. The suboptimal accuracy of the first generation seems to be substantially improved by the second generation of this device...
  2. doi request reprint Computed tomographic colonography to screen for colorectal cancer, extracolonic cancer, and aortic aneurysm: model simulation with cost-effectiveness analysis
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, and Department of Radiological Sciences, University Polo Pontino, Rome, Italy
    Arch Intern Med 168:696-705. 2008
    ..The efficacy and cost-effectiveness of this combined abdominal CT screening strategy are unknown...
  3. doi request reprint Cost effectiveness of colonoscopy, based on the appropriateness of an indication
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Clin Gastroenterol Hepatol 6:1231-6. 2008
    ....
  4. ncbi request reprint Appropriateness of the indication for colonoscopy: systematic review and meta-analysis
    Cesare Hassan
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italia
    J Gastrointestin Liver Dis 20:279-86. 2011
    ..To perform a systematic review and meta-analysis to assess the accuracy of ASGE and EPAGE guidelines in selecting patients referred for OC, relative to the detection of neoplastic and non-neoplastic relevant endoscopic findings...
  5. pmc New paradigms for colonoscopic management of diminutive colorectal polyps: predict, resect, and discard or do not resect?
    Cesare Hassan
    Digestive Endoscopy Unit, Istituto Clinico Humanitas, Milan, Italy
    Clin Endosc 46:130-7. 2013
    ..Aim of this review is to summarize the data supporting the application of both a predict-and-do-not-resect and a predict-resect-and-discard policies, also addressing the potential pitfalls associated with these strategies...
  6. pmc Computed tomographic colonography for colorectal cancer screening: risk factors for the detection of advanced neoplasia
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Cancer 119:2549-54. 2013
    ....
  7. ncbi request reprint Colonic polyps: are we ready to resect and discard?
    Cesare Hassan
    Digestive Endoscopy Unit, IRCCS Istituto Clinico Humanitas, Via Manzoni 56, Rozzano, Milan 20089, Italy
    Gastrointest Endosc Clin N Am 23:663-78. 2013
    ..The aim of this review is to summarize the data supporting the clinical application of a resect and discard strategy, also addressing the potential pitfalls associated with this approach...
  8. doi request reprint Management of subcentimetric polyps detected by CT colonography
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Via Morosini 30, 00153 Rome, Italy
    Nat Rev Gastroenterol Hepatol 10:119-24. 2013
    ..These policies might be further refined by the inclusion of patient and polyp-related predictive factors for advanced neoplasia, enabling a patient-tailored approach for the management of these lesions...
  9. doi request reprint Meta-analysis: adherence to colorectal cancer screening and the detection rate for advanced neoplasia, according to the type of screening test
    C Hassan
    Laziosanita Agenzia di sanita pubblica, Regione Lazio, Rome, Italy
    Aliment Pharmacol Ther 36:929-40. 2012
    ..The efficacy and effectiveness of different tests are related to both screened participation and the detection rate...
  10. doi request reprint Cost-effectiveness of CT colonography
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Roma 00153, Italy
    Radiol Clin North Am 51:89-97. 2013
    ..Fortunately, both conditions appear to be achievable if CTC becomes a widely utilized and reimbursed screening tool...
  11. ncbi request reprint Loss of efficacy and cost-effectiveness when screening colonoscopy is performed by nongastroenterologists
    Cesare Hassan
    Division of Gastroenterology, Nuovo Regina Margherita Hospital, Rome, Italy
    Cancer 118:4404-11. 2012
    ..Specialty of the endoscopist has been related to the postcolonoscopy interval risk of colorectal cancer (CRC). However, the impact of such a difference on the long-term CRC prevention rate by screening colonoscopy is largely unknown...
  12. doi request reprint Primary prevention of colorectal cancer with low-dose aspirin in combination with endoscopy: a cost-effectiveness analysis
    Cesare Hassan
    Ospedale Nuovo Regina Margherita, Gastroenterologia ed Endoscopia Digestiva, Via Morosini 30, 00153, Roma, Italia
    Gut 61:1172-9. 2012
    ..Colonoscopy has been either less effective or ineffective in the proximal compared to the distal colon. The authors assessed the cost-effectiveness of adding low-dose aspirin to a simulated screening with colonoscopy or sigmoidoscopy...
  13. doi request reprint Endoscopist-directed propofol administration versus anesthesiologist assistance for colorectal cancer screening: a cost-effectiveness analysis
    C Hassan
    Gastroenterology Department, Nuovo Regina Margherita Hospital, Rome, Italy
    Endoscopy 44:456-64. 2012
    ..Endoscopist-directed administration of propofol (EDP) by nonanesthesiologists has recently been proposed, with potential savings of anesthetist reimbursement costs. We aimed to assess potential EDP-related benefit in a screening setting...
  14. ncbi request reprint A predictive model identifies patients most likely to have inadequate bowel preparation for colonoscopy
    Cesare Hassan
    Endoscopy Unit, Humanitas Irccs, Rozzano, Milano, Italy
    Clin Gastroenterol Hepatol 10:501-6. 2012
    ..We searched for factors associated with an inadequate level of preparation and tested the validity of a predictive clinical rule based on these factors...
  15. doi request reprint Cost-effectiveness of early colonoscopy surveillance after cancer resection
    C Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Dig Liver Dis 41:881-5. 2009
    ..Short-interval surveillance colonoscopy at 1 year has been recently recommended following curative-intent surgery for colorectal cancer. However, the efficacy and cost-effectiveness of this endoscopic strategy is largely unknown...
  16. ncbi request reprint Cost-effectiveness of endoscopic surveillance for gastric intestinal metaplasia
    Cesare Hassan
    Nuovo Regina Margherita Hospital, Rome, Italy
    Helicobacter 15:221-6. 2010
    ..Cost-effectiveness of endoscopic surveillance in IM patients is unknown. To assess the efficacy and cost-effectiveness of an yearly endoscopic surveillance in patients with IM...
  17. doi request reprint Cost effectiveness and projected national impact of colorectal cancer screening in France
    C Hassan
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    Endoscopy 43:780-93. 2011
    ..Although immunochemical fecal tests (FIT) and guaiac-based fecal occult blood tests (g-FOBT) have been shown to be cost-effective in France, cost-effectiveness of endoscopic screening has not yet been addressed...
  18. ncbi request reprint Cost-effectiveness of capsule endoscopy in screening for colorectal cancer
    C Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Endoscopy 40:414-21. 2008
    ....
  19. doi request reprint A resect and discard strategy would improve cost-effectiveness of colorectal cancer screening
    Cesare Hassan
    Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Clin Gastroenterol Hepatol 8:865-9, 869.e1-3. 2010
    ..We modeled the cost-effectiveness of this policy...
  20. doi request reprint Impact of whole-body CT screening on the cost-effectiveness of CT colonography
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Via Morosini 30, 00153, Rome, Italy
    Radiology 251:156-65. 2009
    ....
  21. doi request reprint Impact of lifestyle factors on colorectal polyp detection in the screening setting
    C Hassan
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Dis Colon Rectum 53:1328-33. 2010
    ..Awareness of risk factors for colorectal neoplasia could address risk reduction strategies in asymptomatic subjects...
  22. ncbi request reprint Projected impact of colorectal cancer screening with computerized tomographic colonography on current radiological capacity in Europe
    C Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Aliment Pharmacol Ther 27:366-74. 2008
    ..The multispecialty needs for computerized tomographic examinations raise some doubts on the feasibility of a mass colorectal cancer screening with computerized tomographic colonography...
  23. ncbi request reprint Performance improvements of imaging-based screening tests
    Cesare Hassan
    Nuovo Regina Margherita Hospital, Via Morosini 30, 00153 Rome, Italy
    Best Pract Res Clin Gastroenterol 24:493-507. 2010
    ..Colon capsule endoscopy appears to be a safe and technically feasible procedure. The suboptimal accuracy of the first generation seems to be substantially improved by the second generation of this device...
  24. doi request reprint Cost-effectiveness of early one-year colonoscopy surveillance after polypectomy
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Dis Colon Rectum 52:964-71; discussion 971. 2009
    ..The purpose of this study was to assess the clinical and economic impact of early surveillance colonoscopy one year after polypectomy in relation to detection of colorectal cancer...
  25. ncbi request reprint Value-of-information analysis to guide future research in colorectal cancer screening
    Cesare Hassan
    Digestive and Liver Disease Unit, Universita di Roma La Sapienza, Sant Andrea Hospital, Rome, Italy
    Radiology 253:745-52. 2009
    ..To identify the most useful areas for research in colorectal cancer (CRC) screening by using a value-of-information analysis...
  26. ncbi request reprint Value-of-information analysis to guide future research in the management of the colorectal malignant polyp
    Cesare Hassan
    Digestive and Liver Disease Unit, University La Sapienza, Endoscopy, Sant Andrea Hospital, Rome, Italy
    Dis Colon Rectum 53:135-42. 2010
    ..The purpose of this study was to guide future research on the optimal strategy for low-risk polyps with the use of value-of-information analysis...
  27. ncbi request reprint Systematic review: distribution of advanced neoplasia according to polyp size at screening colonoscopy
    C Hassan
    Nuovo Regina Margherita Hospital, Rome, Italy
    Aliment Pharmacol Ther 31:210-7. 2010
    ..The impact of not referring sub-centimetre polyps identified at CT colonography upon the efficacy of colorectal cancer screening remains uncertain...
  28. ncbi request reprint Tumor necrosis factor alpha in ulcerative colitis and diverticular disease associated colitis
    C Hassan
    Ospedale Nuovo Regina Margherita, Gastroenterologia ed Endoscopia Digestiva, Via Morosini 30, 00153, Roma, Italia
    Endocr Metab Immune Disord Drug Targets 7:187-94. 2007
    ..The aim of this review is to provide an insight into the role of TNF-alpha and anti-TNF-alpha therapy in patients with UC and diverticular disease associated colitis...
  29. ncbi request reprint Systematic review: Endoscopic dilatation in Crohn's disease
    C Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Aliment Pharmacol Ther 26:1457-64. 2007
    ..Endoscopic dilatation for Crohn's disease has been evaluated only in some small and heterogeneous studies...
  30. ncbi request reprint Gastric mucosa alterations in first-degree relatives of gastric cancer patients
    Adriana Romiti
    Oncology, Sant Andrea Hospital, Rome, Italy
    Anticancer Res 25:2567-72. 2005
    ..On the other hand, both gastric cell hyperproliferation and abnormalities of adhesion molecules have been involved in gastric carcinogenesis. We studied gastric mucosa alterations in first-degree relatives of gastric cancer patients...
  31. ncbi request reprint Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy
    Vincenzo De Francesco
    Gastroenterology Unit, Ospedali Riuniti, Foggia, Italy
    J Antimicrob Chemother 59:783-5. 2007
    ....
  32. ncbi request reprint Appropriateness guidelines and predictive rules to select patients for upper endoscopy: a nationwide multicenter study
    Luigi Buri
    Gastroenterology and Digestive Endoscopy Unit, Cattinara Hospital, Trieste, Italy
    Am J Gastroenterol 105:1327-37. 2010
    ....
  33. doi request reprint Cost-effectiveness of upper gastrointestinal endoscopy according to the appropriateness of the indication
    Emilio Di Giulio
    Digestive and Liver Disease Unit, Second Medical School, University La Sapienza, Sant Andrea Hospital, Rome, Italy
    Scand J Gastroenterol 44:491-8. 2009
    ..The aim of this study was to assess the clinical and economic impact of ASGE and EPAGE guidelines in selecting patients referred for upper endoscopy relative to the detection of gastro-oesophageal cancer...
  34. doi request reprint Effects of Helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Clin Gastroenterol Hepatol 8:105-10. 2010
    ..We assessed the long-term remission and relapse rates of early stage MALT lymphoma in patients treated only by H pylori eradication and identified factors that might predict outcome...
  35. pmc Intestinal metaplasia surveillance: searching for the road-map
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, 00153 Rome, Italy
    World J Gastroenterol 19:1523-6. 2013
    ..Finally, some data would suggest that a 3-year follow-up in patients with extensive gastric precancerous conditions could result in an inadequate secondary prevention...
  36. doi request reprint Primary low-grade and high-grade gastric MALT-lymphoma presentation
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Haematology, Nuovo Regina Margherita Hospital, La Sapienza University, Rome, Italy
    J Clin Gastroenterol 44:340-4. 2010
    ..To assess the clinical and endoscopic presentation of primary gastric lymphoma...
  37. doi request reprint Helicobacter pylori vacA arrangement and related diseases: a retrospective study over a period of 15 years
    Vincenzo De Francesco
    Gastroenterology Unit, Ospedali Riuniti, Foggia, Italy
    Dig Dis Sci 54:97-102. 2009
    ..Our results show some unexpected aspects that require confirmation. In detail, the increased prevalence of potential more virulent H. pylori strains contrasts with peptic ulcer incidence reduction...
  38. doi request reprint Eradication therapy for Helicobacter pylori in patients with gastric MALT lymphoma: a pooled data analysis
    Angelo Zullo
    Department of Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Via E Morosini, 30, Rome 00153, Italy
    Am J Gastroenterol 104:1932-7; quiz 1938. 2009
    ..This study assesses (i) the H. pylori eradication rates for various first- and second-line and rescue therapies and (ii) the associated reinfection rates in patients...
  39. ncbi request reprint Relationship between beta-catenin expression and epithelial cell proliferation in gastric mucosa with intestinal metaplasia
    Adriana Romiti
    Medical Oncology, Sant Andrea Hospital, Rome, Italy
    World J Gastroenterol 11:4400-3. 2005
    ..To investigate beta-catenin expression in patients with intestinal metaplasia, and to look for a possible relationship between beta-catenin expression and either epithelial proliferation values or Helicobacter pylori (H pylori) infection...
  40. ncbi request reprint Endoscopic submucosal dissection of early gastric neoplastic lesions: a western series
    Alessandro Repici
    aDepartment of Gastroenterology, Digestive Endoscopy Unit, IRCCS Istituto Clinico Humanitas, Milan bDepartment of Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Eur J Gastroenterol Hepatol 25:1261-4. 2013
    ..However, few data are available on the use of ESD in western countries. We assessed the efficacy of ESD performed in patients with early gastric neoplastic lesions...
  41. doi request reprint Helicobacter pylori management in non-steroidal anti-inflammatory drug therapy patients in primary care
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Via E Morosini, 30, 00153 Rome, Italy
    Intern Emerg Med 7:331-5. 2012
    ..pylori infection is investigated in fewer than one of every five NSAID-user patients in primary care. The low alertness towards such an infection in these patients suggests a need for prompt implementation of current guidelines...
  42. doi request reprint Low prevalence of idiopathic peptic ulcer disease: an Italian endoscopic survey
    Andrea Sbrozzi-Vanni
    Department of Digestive and Liver Diseases, University Sapienza, Sant Andrea Hospital, Rome, Italy
    Dig Liver Dis 42:773-6. 2010
    ..Peptic ulcer disease (PUD) represents a common condition, although its incidence is decreasing. Previous studies reported a high rate of idiopathic PUD prevalence...
  43. doi request reprint PillCam colon capsule endoscopy: a prospective, randomized trial comparing two regimens of preparation
    Cristiano Spada
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    J Clin Gastroenterol 45:119-24. 2011
    ..Aim of this study is to assess the feasibility of substituting sodium phosphate (NaP) with polyethylene glycol (PEG)-boosters in the protocol preparation for PillCam Colon Capsule Endoscopy (CCE)...
  44. doi request reprint A new regimen of bowel preparation for PillCam colon capsule endoscopy: a pilot study
    Cristiano Spada
    Digestive Endoscopy Unit, Catholic University, Largo Francesco Vito 1, Rome, Italy
    Dig Liver Dis 43:300-4. 2011
    ..Colon capsule endoscopy (CCE) represents a new diagnostic, endoscopic technology for colonic exploration. Current protocols of preparation led to discordant rates of adequate cleansing level or CCE excretion...
  45. ncbi request reprint Accuracy of narrow-band imaging in predicting colonoscopy surveillance intervals and histology of distal diminutive polyps: results from a multicenter, prospective trial
    Alessandro Repici
    Digestive Endoscopy Unit, Istituto Clinico Humanitas, Milan, Italy
    Gastrointest Endosc 78:106-14. 2013
    ..In vivo prediction of colorectal polyp histology by narrow-band imaging (NBI) could potentially avoid post-polypectomy histologic examination or resection of diminutive lesions, thereby reducing costs and risk...
  46. ncbi request reprint 13C-urea breath test values and Helicobacter pylori eradication
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Via E Morosini, 30, Rome 00153, Italy
    Dig Dis Sci 53:370-4. 2008
    ..This large analysis failed to demonstrate a role for DOB value in H. pylori eradication with either a 10-day triple or sequential therapy...
  47. doi request reprint High efficacy of endoscopic submucosal dissection for rectal laterally spreading tumors larger than 3 cm
    Alessandro Repici
    Department of Gastroenterology, IRCCS Istituto Clinico Humanitas, Milan, Italy
    Gastrointest Endosc 77:96-101. 2013
    ..The endoscopic technique is technically demanding and not yet standardized, and new devices are needed...
  48. pmc Balanced propofol sedation administered by nonanesthesiologists: The first Italian experience
    Alessandro Repici
    Department of Gastroenterology, IRCCS Istituto Clinico Humanitas, Via Manzoni 56 20089 Rozzano, Milan, Italy
    World J Gastroenterol 17:3818-23. 2011
    ..To assess the efficacy and safety of a balanced approach using midazolam in combination with propofol, administered by non-anesthesiologists, in a large series of diagnostic colonoscopies...
  49. doi request reprint Appropriateness of the indication for colonoscopy: is the endoscopist the 'gold standard'?
    Lucio Petruzziello
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    J Clin Gastroenterol 46:590-4. 2012
    ..The appropriate selection of patients for colonoscopy is crucial for an efficient use of endoscopy. The role of endoscopist in filtering out inappropriate referrals is largely unknown...
  50. ncbi request reprint [Current understanding of the role of virtual colonoscopy in abdominal diagnosis]
    Cesare Hassan
    Unità di Gastroenterologia e di Endoscopia Digestiva, Ospedale Nuovo Regina Margherita, Roma
    Recenti Prog Med 100:61-7. 2009
    ....
  51. ncbi request reprint Gastric epithelial cell proliferation and ras oncogene p21 expression in first-degree relatives of gastric cancer patients: a case-control study
    Angelo Zullo
    Department of Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Eur J Gastroenterol Hepatol 18:921-6. 2006
    ..Individuals with a family history of gastric cancer have an increased risk of developing such neoplasia. This study aimed to assess epithelial cell proliferation and ras oncogene mutation in such individuals...
  52. ncbi request reprint Second-line and rescue therapies for Helicobacter pylori eradication in clinical practice
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    J Gastrointestin Liver Dis 19:131-4. 2010
    ..pylori eradication. However, no data are available for the efficacy of these treatments in clinical practice...
  53. doi request reprint Role of gastritis pattern on Helicobacter pylori eradication
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Intern Emerg Med 7:517-22. 2012
    ..The multivariate analysis failed to identify factors associated with therapy success. However, 14-day triple therapy does not achieve acceptable H. pylori cure rate in Italy, and should be not recommended in clinical practice...
  54. ncbi request reprint Claritromycin resistance and Helicobacter pylori genotypes in Italy
    Vincenzo De Francesco
    Gastroenterology Unit, Riuniti Hospital, Foggia, Italy
    J Microbiol 44:660-4. 2006
    ..Primary clarithromycin resistance is high in our area. The s1m1 and s1m2 are the most frequent vacA mosaicisms. There is no a relationship between clarithromycin resistance and bacterial genotypic pattern and/or cagA positivity...
  55. ncbi request reprint Endoscopic submucosal dissection of gastric neoplastic lesions in patients with liver cirrhosis: a systematic review
    Alessandro Repici
    Department of Gastroenterology, IRCCS Istituto Clinico Humanitas, Milan, Italy
    J Gastrointestin Liver Dis 21:303-7. 2012
    ..We evaluated data on feasibility and safety of ESD for gastric lesions in cirrhotic patients...
  56. doi request reprint A new low-volume isosmotic polyethylene glycol solution plus bisacodyl versus split-dose 4 L polyethylene glycol for bowel cleansing prior to colonoscopy: a randomised controlled trial
    Paola Cesaro
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    Dig Liver Dis 45:23-7. 2013
    ..A new isosmotic low-volume polyethylene glycol preparation with citrates and simethicone plus bisacodyl has been developed to improve patient compliance and tolerability...
  57. doi request reprint Modified sequential therapy regimens for Helicobacter pylori eradication: a systematic review
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Dig Liver Dis 45:18-22. 2013
    ..Different modified sequential therapies have been proposed for Helicobacter pylori eradication. However, the efficacy of these regimens is controversial...
  58. doi request reprint Treatment of low-grade gastric MALT-lymphoma unresponsive to Helicobacter pylori therapy: a pooled-data analysis
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Via E Morosini 30, 00153 Rome, Italy
    Med Oncol 27:291-5. 2010
    ..pylori eradication. Radiotherapy seems to be the most suitable treatment in these patients...
  59. doi request reprint Detection of colonic polyps according to insertion/withdrawal phases of colonoscopy
    Sergio Morini
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Int J Colorectal Dis 24:527-30. 2009
    ..Recently, a >6-min withdrawal time has been recommended. However, the relative prevalence of polyp detected during insertion and withdrawal phases of colonoscopy is unknown. Therefore, we designed this prospective, endoscopic study...
  60. ncbi request reprint Cyclic antibiotic therapy for diverticular disease: a critical reappraisal
    Angelo Zullo
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    J Gastrointestin Liver Dis 19:295-302. 2010
    ..The available studies have been hampered by some limitations, and definite conclusions could not be drawn. The cost of a long-life, cyclic rifaximin therapy administered to all symptomatic DD patients would appear prohibitive...
  61. doi request reprint Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings
    Luigi Buri
    Gastroenterology and Digestive Endoscopy Unit, Cattinara Hospital, Trieste, Italy
    Intern Emerg Med 8:141-6. 2013
    ..Peptic ulcer or malignancies were detected in 10% of elderly patients, supporting the use of endoscopy in this age group. Very elderly patients appear to be at higher risk of such lesions...
  62. doi request reprint Endoscopic management of failed colonoscopy in clinical practice: to change endoscopist, instrument, or both?
    Sergio Morini
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Int J Colorectal Dis 26:103-8. 2011
    ....
  63. doi request reprint Diverticulosis and colorectal cancer: between lights and shadows
    Sergio Morini
    Gastronterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    J Clin Gastroenterol 42:763-70. 2008
    ..Despite this substantial amount of evidence, however, the available data are not yet strong enough to suggest a more aggressive CRC prevention in diverticular as compared with nondiverticular subjects...
  64. pmc The sequential therapy regimen for Helicobacter pylori eradication: a pooled-data analysis
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Gut 56:1353-7. 2007
    ..However, a critical fall in the H pylori eradication rate following these therapies has been observed in the last few years. The sequential regimen is a novel, promising therapeutic approach...
  65. ncbi request reprint Retrograde ileoscopy in chronic nonbloody diarrhea: a prospective, case-control study
    Sergio Morini
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Am J Gastroenterol 98:1512-5. 2003
    ..Besides colonic diseases, alterations of the terminal ileum could be involved in CND pathogenesis. The aim of this study was to assess the role of retrograde ileoscopy with biopsy in CND patients...
  66. pmc Endoscopic findings in patients with upper gastrointestinal bleeding clinically classified into three risk groups prior to endoscopy
    Leonardo Tammaro
    Gastroenterologia ed Endoscopia Digestiva, Ospedale Nuovo Regina Margherita, Via E Morosini 300, Rome, Italy
    World J Gastroenterol 14:5046-50. 2008
    ..To investigate in a prospective study whether a simplified clinical score prior to endoscopy in upper gastrointestinal bleeding (UGIB) patients was able to predict endoscopic findings at urgent endoscopy...
  67. ncbi request reprint Histologic risk factors and clinical outcome in colorectal malignant polyp: a pooled-data analysis
    Cesare Hassan
    Department of Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Dis Colon Rectum 48:1588-96. 2005
    ..The study was designed to compute the association between the main histologic risk factors and the occurrence of unfavorable outcomes in patients with malignant polyps...
  68. ncbi request reprint Computed tomography enteroclysis in comparison with ileoscopy in patients with Crohn's disease
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Via E Morosini 30, 00153 Rome, Italy
    Int J Colorectal Dis 18:121-5. 2003
    ....
  69. doi request reprint Second-generation colon capsule endoscopy compared with colonoscopy
    Cristiano Spada
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    Gastrointest Endosc 74:581-589.e1. 2011
    ..A second-generation colon capsule endoscopy system (PillCam Colon 2) (CCE-2) was developed to increase sensitivity for colorectal polyp detection compared with the first-generation system...
  70. ncbi request reprint Helicobacter pylori density and cagA status in cirrhotic patients: a case-control study
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    J Gastroenterol Hepatol 19:1174-8. 2004
    ..We evaluated whether cirrhotic patients had an increased bacterial density and/or a higher prevalence of H. pylori cagA-positive strains than controls...
  71. doi request reprint Literature review and recommendations for clinical application of Colon Capsule Endoscopy
    Cristiano Spada
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    Dig Liver Dis 43:251-8. 2011
    ..The available evidence served to propose recommendations for preparation protocols, proper test indications and Colon Capsule Endoscopy procedure. Possible perspectives were also critically analysed and are reported in this paper...
  72. pmc Furazolidone-based therapies for Helicobacter pylori infection: a pooled-data analysis
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Saudi J Gastroenterol 18:11-7. 2012
    ..The low bacterial resistance toward furazolidone may render appealing the use of this drug even in developed countries. However, some relevant safety concerns do exist in using furazolidone...
  73. ncbi request reprint Alteration of E-cadherin expression in gastric mucosa: role of intestinal metaplasia and Helicobacter pylori infection
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Anticancer Res 24:1603-7. 2004
    ..This study aimed to assess the role of both intestinal metaplasia and H. pylori infection on E-cadherin expression in gastric mucosa...
  74. ncbi request reprint Ileal intubation with a transnasal endoscope
    Vincenzo Pietropaolo
    Digestive Endoscopy Unit, La Sapienza University, Rome, Italy
    Eur J Gastroenterol Hepatol 22:374-5. 2010
    ..We report the feasibility of performing a full colonic study with ileal intubation, using a small-caliber endoscope commonly used for transanal endoscopy, after failing with a standard gastroscope...
  75. ncbi request reprint Appropriateness of upper-GI endoscopy: an Italian survey on behalf of the Italian Society of Digestive Endoscopy
    Cesare Hassan
    Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy
    Gastrointest Endosc 65:767-74. 2007
    ..The aim of this Italian multicenter study was to assess the appropriate use of upper endoscopy (EGD) in an open-access system and to establish the yield of diagnostic information relevant to patient care...
  76. ncbi request reprint Meta-analysis shows colon capsule endoscopy is effective in detecting colorectal polyps
    Cristiano Spada
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    Clin Gastroenterol Hepatol 8:516-22. 2010
    ..We performed a systematic review and meta-analysis to assess the accuracy of CCE in detecting colorectal polyps...
  77. pmc Accuracy and safety of second-generation PillCam COLON capsule for colorectal polyp detection
    Cristiano Spada
    Digestive Endoscopy Unit, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168 Roma, Italy
    Therap Adv Gastroenterol 5:173-8. 2012
    ..Recently, a second-generation system (PillCam COLON 2) (CCE-2) has been developed to increase sensitivity for colorectal polyp detection. In this review, accuracy and safety data for CCE-2 are analyzed...
  78. pmc Follow-up of intestinal metaplasia in the stomach: When, how and why
    Angelo Zullo
    Angelo Zullo, Cesare Hassan, Michela Giusto, Carmine Guerriero, Roberto Lorenzetti, Salvatore MA Campo, Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, 00153 Rome, Italy
    World J Gastrointest Oncol 4:30-6. 2012
    ..In the remaining IM patients, a less intensive (2-3 years) could be proposed...
  79. ncbi request reprint Bleeding peptic ulcer in the elderly: risk factors and prevention strategies
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Drugs Aging 24:815-28. 2007
    ..In conclusion, upper gastrointestinal bleeding is a dramatic event with a high mortality rate, particularly in the elderly. Some effective preventative strategies are now available that should be implemented in clinical practice...
  80. ncbi request reprint Long-term survival in metastatic pancreatic cancer. A case report and review of the literature
    Gian Paolo Spinelli
    Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy
    JOP 7:486-91. 2006
    ..Pancreatic cancer still remains an incurable disease. The survival rate of patients in all stages of the disease is poor. Overall median survival is 3-5 months with a 12-month survival rate of 10% and a 5-year survival rate less than 5%...
  81. doi request reprint A very high rate of inappropriate use of gastroprotection for nonsteroidal anti-inflammatory drug therapy in primary care: a cross-sectional study
    Sergio Morini
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    J Clin Gastroenterol 45:780-4. 2011
    ..To assess the appropriateness of gastroprotection in nonsteroidal anti-inflammatory drug (NSAID) users by primary care physicians...
  82. pmc Palliation with oesophageal metal stent of pseudoachalasia from gastric carcinoma at the cardia: a case report
    Salvatore Maria Antonio Campo
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Via Morosini 30, 00153 Rome, Italy
    Diagn Ther Endosc 2009:791627. 2009
    ....
  83. ncbi request reprint Endoscopic submucosal dissection in patients with early esophageal squamous cell carcinoma: results from a prospective Western series
    Alessandro Repici
    Gastroenterology Department, IRCCS Istituto Clinico Humanitas, Milan, Italy
    Gastrointest Endosc 71:715-21. 2010
    ..Although endoscopic submucosal dissection (ESD) is becoming accepted as an established treatment for superficial esophageal squamous cell neoplasia, the majority of data on this endoscopic modality has been provided by Japanese series...
  84. ncbi request reprint Adenocarcinoma of the ileoanal pouch anastomosis: an emerging complication?
    Cesare Hassan
    Department of Gastroenterology, Nuovo Regina Margherita Hospital, Via E Morosini 30, 00153 Rome, Italy
    Int J Colorectal Dis 18:276-8. 2003
    ..To date, only two cases of carcinoma of the IPAA have been reported, namely in patients operated on for colon cancer complicating ulcerative colitis and with a previous diagnosis of backwash ileitis...
  85. pmc Gastric low-grade mucosal-associated lymphoid tissue-lymphoma: Helicobacter pylori and beyond
    Angelo Zullo
    Angelo Zullo, Cesare Hassan, Francesca Cristofari, Sergio Morini, Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, 00153 Roma, Italy
    World J Gastrointest Oncol 2:181-6. 2010
    ..The 5-year survival rate is higher than 90%, but careful, long-term follow-up is required in these patients since lymphoma recurrence has been reported in some cases...
  86. ncbi request reprint Hepatic encephalopathy and Helicobacter pylori: a critical reappraisal
    Angelo Zullo
    Ospedale Nuovo Regina Margherita, Gastroenterologia ed Endoscopia Digestiva, Via E Morosini, 30 00153 Roma, Italia
    J Clin Gastroenterol 37:164-8. 2003
    ..pylori urease appears to be inadequate to clinically affect ammonia disposal in the majority of cirrhotic patients. Further studies are warranted in this field...
  87. pmc Furazolidone therapy for Helicobacter pylori: is it effective and safe?
    Vincenzo De Francesco
    World J Gastroenterol 15:1914-5. 2009
    ..The inclusion of furazolidone in a treatment regimen for H pylori infection is, at least, controversial, and it does not appear to be safe...
  88. doi request reprint Is there sufficient MDCT capacity to provide colorectal cancer screening with CT colonography for the U.S. population?
    Perry J Pickhardt
    Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
    AJR Am J Roentgenol 190:1044-9. 2008
    ..Our aim was to assess the ability of the available MDCT capacity in the United States to provide population screening with CTC...
  89. ncbi request reprint Small and diminutive polyps detected at screening CT colonography: a decision analysis for referral to colonoscopy
    Perry J Pickhardt
    Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
    AJR Am J Roentgenol 190:136-44. 2008
    ..The objective of this study was to assess the clinical and economic impact of colonoscopic referral for small and diminutive polyps detected at CT colonography (CTC) screening...
  90. ncbi request reprint Tumour necrosis factor alpha in segmental colitis associated with diverticula
    Enzo Ierardi
    Section of Gastroenterology, Department of Medical Sciences, University of Foggia, Ospedali Riuniti, viale L Pinto, Foggia 71100, Italy
    Dig Dis Sci 53:1865-8. 2008
    ..3 +/- 3/mm2). These values were distinctly higher than those found in the IBS controls. Our data suggest that TNF-alpha activity is involved in SCAD pathogenesis, similarly to what occurs in Crohn's disease and ulcerative colitis...
  91. ncbi request reprint Cost-effectiveness of colorectal cancer screening with computed tomography colonography: the impact of not reporting diminutive lesions
    Perry J Pickhardt
    Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792 3252, USA
    Cancer 109:2213-21. 2007
    ..The purpose of the current study was to assess the potential harms, benefits, and cost-effectiveness of CTC screening without the reporting of diminutive lesions compared with other screening strategies...
  92. ncbi request reprint Endoscopy or radiology in nonagenarians?
    Sergio Morini
    J Clin Gastroenterol 41:343-4. 2007
  93. ncbi request reprint A quintuple therapy for H. pylori eradication
    Angelo Zullo
    Am J Gastroenterol 102:2601; author reply 2601-2. 2007
  94. ncbi request reprint Submucosal nodules containing purulent fluid: a colonoscopic sign of actinomycosis?
    Sergio Morini
    Gastroenterology and Digestive Endoscopy, USA
    Gastrointest Endosc 59:319-21. 2004