The incidence and prognostic significance of new-onset atrial fibrillation in patients with acute myocardial infarction and left ventricular systolic dysfunction: a CARISMA substudyChristian Jons
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Heart Rhythm 8:342-8. 2011
..The incidence and risk associated with new-onset atrial fibrillation (AF) occurring after discharge in patients with acute myocardial infarction (MI) remains unknown...
Treating cardiac arrhythmias detected with an implantable cardiac monitor in patients after an acute myocardial infarctionChristian Jons
Gentofte University Hospital, Niels Andersens Vej 65, 2900, Copenhagen, Denmark
Curr Treat Options Cardiovasc Med 14:39-49. 2012
..Thus, patients with nonsustained VT should undergo careful investigation, and we recommend a repeat echocardiography and electrophysiological stimulation in these patients. Patients with sustained VT or VF should receive an ICD...
Autonomic dysfunction and new-onset atrial fibrillation in patients with left ventricular systolic dysfunction after acute myocardial infarction: a CARISMA substudyChristian Jons
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
J Cardiovasc Electrophysiol 21:983-90. 2010
..The purpose of this study was to identify patients with a high risk for new-onset AF in this population using invasive and noninvasive electrophysiological tests...
Diastolic dysfunction predicts new-onset atrial fibrillation and cardiovascular events in patients with acute myocardial infarction and depressed left ventricular systolic function: a CARISMA substudyChristian Jons
Department of Cardiology P, Gentofte University Hospital, Copenhagen, Denmark
Eur J Echocardiogr 11:602-7. 2010
....
The prognostic importance of a history of hypertension in patients with symptomatic heart failure is substantially worsened by a short mitral inflow deceleration timeCharlotte Andersson
Department of Cardiology, Gentofte Hospital, Hellerup, Denmark
BMC Cardiovasc Disord 12:30. 2012
..Hypertension is a common comorbidity in patients with heart failure and may contribute to development and course of disease, but the importance of a history of hypertension in patients with prevalent heart failure remains uncertain...
Prognostic importance of quantitative echocardiographic evaluation in patients suspected of first non-massive pulmonary embolismJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
Eur J Echocardiogr 10:89-95. 2009
..Patients suspected of acute pulmonary embolism (PE) frequently undergo echocardiography as a part of the initial work-up. Prognostic implication of routine echocardiography in patients suspected of PE remain to be established...
Exercise hemodynamics in patients with and without diastolic dysfunction and preserved ejection fraction after myocardial infarctionMads J Andersen
Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Circ Heart Fail 5:444-51. 2012
..Left ventricular diastolic dysfunction (DD) is common after myocardial infarction (MI) despite preservation of left ventricular ejection fraction, yet it remains unclear how or whether DD affects cardiac hemodynamics with stress...
Major cerebral events in Staphylococcus aureus infective endocarditis: is anticoagulant therapy safe?Rasmus V Rasmussen
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Cardiology 114:284-91. 2009
..To study the impact of anticoagulation on major cerebral events in patients with left-sided Staphylococcus aureus infective endocarditis (IE)...
Right ventricular function with hypoxic exercise: effects of sildenafilJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Eur J Appl Physiol 102:87-95. 2007
..This effect seems independent of the effect of sildenafil on RVSP...
Isovolumic acceleration measured by tissue Doppler echocardiography is preload independent in healthy subjectsMorten Dalsgaard
Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Echocardiography 24:572-9. 2007
..IVA is believed to be less dependent on preload than previously proposed estimates. IVA has been measured at different locations, and studies have shown conflicting results...
Infective endocarditis: long-term reversibility of kidney function impairment. A 1-y post-discharge follow-up studyKristine Buchholtz
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Scand J Infect Dis 42:484-90. 2010
..1% of patients with an EECC decrease of >22%. In conclusion, kidney function impairment occurring during hospitalization for IE is potentially reversible within the first y post-discharge...
Atrial fibrillation in heart failure is associated with an increased risk of death only in patients with ischaemic heart diseaseJakob Raunsø
Department of Cardiology, Gentofte Hospital, Copenhagen University Hospital, Post 67, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Eur J Heart Fail 12:692-7. 2010
..In the present study, we investigated the prognostic impact of AF in a large population with HF of various aetiologies...
The relationship between mitral regurgitation and ejection fraction as predictors for the prognosis of patients with heart failureRedi Pecini
Department of Cardiology and Endocrinology, Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
Eur J Heart Fail 13:1121-5. 2011
..To study whether there is interaction between mitral regurgitation (MR) and left ventricular ejection fraction (LVEF) in the mortality risk of heart failure (HF) patients...
Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failureJesper Kjaergaard
The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Cardiovasc Ultrasound 7:51. 2009
..The present study assessed the association of TAPSE and clinical factors, global and regional LV function in 634 patients admitted for symptomatic heart failure...
The prognostic importance of lung function in patients admitted with heart failureKasper Karmark Iversen
The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Eur J Heart Fail 12:685-91. 2010
..The purpose of the present study was to determine the prognostic importance for all-cause mortality of lung function variables obtained by spirometry in an unselected group of patients admitted with heart failure (HF)...
One-year mortality in coagulase-negative Staphylococcus and Staphylococcus aureus infective endocarditisRasmus V Rasmussen
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Scand J Infect Dis 41:456-61. 2009
..aureus IE (p =0.05). In conclusion, CoNS IE was associated with a long diagnostic delay and high in-hospital mortality, whereas post-discharge prognosis was better in this group of patients compared to patients with IE due to S. aureus...
Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist deviceMads Andersen
Department of Cardiology, The Heart Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
JACC Cardiovasc Imaging 3:854-9. 2010
..These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients...
Left ventricular filling pressure estimation at rest and during exercise in patients with severe aortic valve stenosis: comparison of echocardiographic and invasive measurementsMorten Dalsgaard
Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
J Am Soc Echocardiogr 22:343-9. 2009
....
Quantification of right ventricular function in acute pulmonary embolism: relation to extent of pulmonary perfusion defectsJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital Gentofte, Denmark
Eur J Echocardiogr 9:641-5. 2008
..This study evaluated the relation of size of perfusion defects and changes in echocardiographic measures of global and regional RV dysfunction in 58 consecutive patients with non-massive PE...
Quantitative echocardiographic analysis of the right ventricle in healthy individualsJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
J Am Soc Echocardiogr 19:1365-72. 2006
....
Prognostic importance of a short deceleration time in symptomatic congestive heart failureDilek Akkan
The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Eur J Heart Fail 10:689-95. 2008
..We performed a combined evaluation of LV function and RF for prognosis in patients with HF with and without systolic dysfunction...
Long-term impact of diabetes in patients hospitalized with ischemic and non-ischemic heart failureCharlotte Andersson
Department of Cardiology, Gentofte University Hospital, Denmark
Scand Cardiovasc J 44:37-44. 2010
..Diabetes mellitus (DM) in combination with heart failure (HF) is associated with a high risk of death, but it is uncertain whether the prognosis differs in ischemic and non-ischemic HF groups...
Advanced quantitative echocardiography in arrhythmogenic right ventricular cardiomyopathyJesper Kjaergaard
Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
J Am Soc Echocardiogr 20:27-35. 2007
..Three-dimensional echocardiography and Doppler tissue imaging (DTI) are new echocardiographic modalities for the evaluation of global and regional function, but the diagnostic potential remains to be assessed...
Right ventricular dysfunction as an independent predictor of short- and long-term mortality in patients with heart failureJesper Kjaergaard
Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, DK 2100 Copenhagen, Denmark
Eur J Heart Fail 9:610-6. 2007
..Tricuspid annular plane systolic excursion (TAPSE) is a simple echocardiographic measure of RV ejection fraction, but may be affected by co-existing chronic obstructive pulmonary disease (COPD)...
The prognostic value of left atrial peak reservoir strain in acute myocardial infarction is dependent on left ventricular longitudinal function and left atrial sizeMads Ersbøll
The Heart Centre, Department of Cardiology, University Hospital Rigshospitalet, Denmark
Circ Cardiovasc Imaging 6:26-33. 2013
..However, no studies have assessed the interrelation of PALS and left ventricular longitudinal strain (global longitudinal strain) in large-scale populations in regard to prognosis...
Relationship between left ventricular longitudinal deformation and clinical heart failure during admission for acute myocardial infarction: a two-dimensional speckle-tracking studyMads Ersbøll
Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
J Am Soc Echocardiogr 25:1280-9. 2012
..However, many patients develop HF despite preserved LV ejection fractions. The aim of this study was to test the hypothesis that LV longitudinal function is a stronger marker of in-hospital HF than traditional echocardiographic indices...
Clinical characteristics and major comorbidities in heart failure patients more than 85 years of age compared with younger age groupsUlrik Madvig Mogensen
The Heart Centre, Department of Cardiology, University Hospital of Copenhagen, Rigshospitalet, Denmark
Eur J Heart Fail 13:1216-23. 2011
..Heart failure (HF) is increasingly prevalent among the growing number of elderly people, but not well studied. We sought to evaluate disease pattern and importance of prognostic factors among very elderly patients with HF...
The impact of cardiac surgery in native valve infective endocarditis: can euroSCORE guide patient selection?Rasmus V Rasmussen
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Int J Cardiol 149:304-9. 2011
..The objective of this study was to investigate the outcome of surgical treatment and to validate the ability of euroSCORE to predict operative mortality in NVE patients...
The effect of 18 h of simulated high altitude on left ventricular functionJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen Ø, 2100, Denmark
Eur J Appl Physiol 98:411-8. 2006
..The significant changes in filling pattern and IVRT in the setting of normal and unchanged systolic function, indicates that hypoxia induces mild diastolic dysfunction in young healthy individuals...
Global left ventricular longitudinal strain is closely associated with increased neurohormonal activation after acute myocardial infarction in patients with both reduced and preserved ejection fraction: a two-dimensional speckle tracking studyMads Ersbøll
The Heart Centre, Department of Cardiology, University Hospital Rigshospitalet, Denmark
Eur J Heart Fail 14:1121-9. 2012
..However, little is known about the relationship between longitudinal deformation indices and NT-proBNP...
Myocardial hypertrophy after pulmonary regurgitation and valve implantation in pigsJulie Smith
Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Int J Cardiol 159:29-33. 2012
..But the underlying mechanisms of the refractory arrhythmias are not well understood...
Determinants of exercise-induced increase of mitral regurgitation in patients with acute coronary syndromesRedi Pecini
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Echocardiography 27:567-74. 2010
..We describe the determinants of exercise-induced changes in MR in patients with non-ST-elevation acute coronary syndrome (NSTACS)...
Quantitative measures of right ventricular dysfunction by echocardiography in the diagnosis of acute nonmassive pulmonary embolismJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
J Am Soc Echocardiogr 19:1264-71. 2006
....
Promising results after percutaneous mitral valve repairNikolaj Ihlemann
Department of Cardiology, Hjertemedicinsk Klinik B, Rigshospitalet, 2100 Copenhagen, Denmark
Dan Med Bull 58:A4299. 2011
..Percutaneous mitral valve repair with the MitraClip system resembles the Alfieristitch where a clip is used to connect the tip of the mitral valve leaflets...
Prognostic importance of a restrictive transmitral filling pattern in patients with symptomatic congestive heart failure and atrial fibrillationJakob Raunsø
Department of Cardiology, Copenhagen University Hospital, Gentofte Hospital, Copenhagen, Denmark
Am Heart J 158:983-8. 2009
..Most studies have excluded patients with atrial fibrillation. The aim of the present study was to assess the prognostic value of a restrictive filling pattern in patients with atrial fibrillation...
Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiographyRasmus V Rasmussen
Department of Cardiology, Copenhagen University Hospital, Gentofte, Niels Andersens Vej 65, Post 4210, 2900 Hellerup, Denmark
Eur J Echocardiogr 12:414-20. 2011
..In the present study, we prospectively evaluated the importance of screening with echocardiography in an unselected S. aureus bacteraemia (SAB) population...
Hereditary hemochromatosis (HFE) genotypes in heart failure: relation to etiology and prognosisDaniel V Møller
Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
BMC Med Genet 11:117. 2010
..Mutations within several genes are HH-associated, the most common being the HFE gene. In a large cohort of HF patients, we sought to determine the etiological role and the prognostic significance of HFE genotypes...
Comparison of Valsalva manoeuvre and exercise in echocardiographic evaluation of left ventricular outflow tract obstruction in hypertrophic cardiomyopathyMorten K Jensen
Department of Cardiology, 2142 The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark
Eur J Echocardiogr 11:763-9. 2010
..We compared LVOT gradients induced by Valsalva manoeuvre (VM) and exercise echocardiography (EE) in patients with HCM treated with percutaneous transluminal septal myocardial ablation (PTSMA)...
Partial oral treatment of endocarditisKasper Iversen
Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
Am Heart J 165:116-22. 2013
..Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective...
Heart failure etiology impacts survival of patients with heart failureRedi Pecini
Department of Cardiology, University of Copenhagen, Rigshospitalet, Denmark
Int J Cardiol 149:211-5. 2011
..The impact of heart failure (HF) etiology on prognosis of HF is not well known...
Impact of preload and afterload on global and regional right ventricular function and pressure: a quantitative echocardiography studyJesper Kjaergaard
Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
J Am Soc Echocardiogr 19:515-21. 2006
..Several quantitative echocardiographic measures of global and regional right ventricular (RV) function have been proposed, but knowledge of the impact of increases in preload and afterload is limited...
Heart murmur and N-terminal pro-brain natriuretic peptide as predictors of death in 2977 consecutive hospitalized patientsKasper Iversen
Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
Am J Med Sci 335:444-50. 2008
..We wanted to test whether murmur predicts mortality in unselected patients admitted to the hospital and whether NT-pro-BNP is capable of distinguishing between innocent and significant murmurs...
Severity of gentamicin's nephrotoxic effect on patients with infective endocarditis: a prospective observational cohort study of 373 patientsKristine Buchholtz
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark
Clin Infect Dis 48:65-71. 2009
..The aim of this study was to quantify the nephrotoxic effect of gentamicin and the association between the nephrotoxic effect and mortality in patients with IE...
Once versus twice daily gentamicin dosing for infective endocarditis: a randomized clinical trialKristine Buchholtz
Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark krisbuch vip cybercity dk
Cardiology 119:65-71. 2011
..The aim of this randomized study was to investigate the effects of once versus twice daily gentamicin dosing on renal function and measures of infectious disease in a population with infective endocarditis (IE)...
Moderate exercise does not increase the severity of mitral regurgitation due to mitral valve prolapseRedi Pecini
Cardiology Department, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark
Echocardiography 27:1031-7. 2010
..Mitral regurgitation (MR) secondary to ischemic heart disease (IHD) increases during exercise. We tested the hypothesis that the same is also true for MR due to mitral valve prolapse (MVP)...
Evaluation of right ventricular volume and function by 2D and 3D echocardiography compared to MRIJesper Kjaergaard
Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
Eur J Echocardiogr 7:430-8. 2006
....
Left atrial volume in patients with asymptomatic aortic valve stenosis (the Simvastatin and Ezetimibe in Aortic Stenosis study)Morten Dalsgaard
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Am J Cardiol 101:1030-4. 2008
..Furthermore, LA volume is related to AVA even when adjusting for other known risk factors for increased LA volume including of measurements of diastolic function...
In infectious endocarditis patients mortality is highly related to kidney function at time of diagnosis: a prospective observational cohort study of 231 casesKristine Buchholtz
Department of Cardiology, Gentofte University Hospital, Hellerup, Copenhagen, Denmark
Eur J Intern Med 20:407-10. 2009
..A number of complicating conditions are known to be of importance for the outcome. But only few data are available in IE patients on the independent prognostic value of kidney function at the time of admittance...
The impact of therapeutic hypothermia on neurological function and quality of life after cardiac arrestJohn Bro-Jeppesen
Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, DK 2100 Copenhagen, Denmark
Resuscitation 80:171-6. 2009
..To assess the impact of therapeutic hypothermia on cognitive function and quality of life in comatose survivors of out of Hospital Cardiac arrest (OHCA)...
Tissue Doppler imaging as a guide to resynchronization therapy in patients with congestive heart failurePeter Søgaard
Department of Cardiology P, University Hospital, Copenhagen, Denmark
Curr Opin Cardiol 19:447-51. 2004
..Cardiac resynchronization therapy is a nonpharmacological treatment option in patients with heart failure and left bundle branch block but response rates are still disappointing...
Effects of chronic severe pulmonary regurgitation and percutaneous valve repair on right ventricular geometry and contractility assessed by tissue Doppler echocardiographyJesper Kjaergaard
The Heart Centre, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark
Echocardiography 27:854-63. 2010
..Tissue Doppler based quantification of RV contractility may offer additional information in the management of these patients...
Right ventricular strain in pulmonary embolism by Doppler tissue echocardiographyJesper Kjaergaard
Department of Cardiology, University Hospital of Gentofte, Hellerup, Denmark
J Am Soc Echocardiogr 17:1210-2. 2004
..We used strain analysis to demonstrate changes in the regional right ventricular free wall performance during the acute and recovery stages of pulmonary embolism...