A Harmjanz

Summary

Publications

  1. ncbi request reprint Leptin and neuropeptide Y gene expression in human placenta: ontogeny and evidence for similarities to hypothalamic regulation
    J Dotsch
    Universitätsklinik für Kinder und Jugendliche, Erlangen, Germany
    J Clin Endocrinol Metab 84:2755-8. 1999
  2. ncbi request reprint Leptin-induced weight loss is not solely mediated by anorexia
    Jorg Dotsch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
    Eur J Endocrinol 148:11-2. 2003
  3. ncbi request reprint Graves disease in childhood: a review of the options for diagnosis and treatment
    Jorg Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Erlangen, Germany
    Paediatr Drugs 5:95-102. 2003
  4. ncbi request reprint The role of 11beta-hydroxysteroid dehydrogenase activity in the metabolic syndrome: lessons learned from the animal model
    Jorg Dotsch
    Klinik fur Kinder und Jugendliche, Loschgestr 15, 91054 Erlangen, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
    Eur J Endocrinol 146:603-5. 2002
  5. ncbi request reprint Nitric oxide increases adrenomedullin receptor function in rat mesangial cells
    Jorg Dotsch
    Klinik fur Kinder und Jugendliche, and Medizinische Klinik IV, Friedrich Alexander University Erlangen, Erlangen, Germany
    Kidney Int 61:1707-13. 2002
  6. ncbi request reprint Diagnostic and scientific applications of TaqMan real-time PCR in neuroblastomas
    J Dotsch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander University, Erlangen, Loschgestrasse 15 91054 Erlangen, Germany
    Expert Rev Mol Diagn 1:233-8. 2001
  7. ncbi request reprint Nitric oxide stimulates adrenomedullin secretion and gene expression in endothelial cells
    J Dotsch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander Universitat Erlangen Nurnberg, Erlangen, Deutschland
    Pharmacology 64:135-9. 2002
  8. ncbi request reprint Unmasking of childhood hypothyroidism by disseminated xanthomas
    J Dotsch
    Universitätsklinik für Kinder und Jugendliche, Erlangen, Erlagen, Germany
    Pediatrics 108:E96. 2001
  9. ncbi request reprint Effect of glucocorticoid excess on the cortisol/cortisone ratio
    J Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Loschgestr 15, D 91054 Erlangen, Germany
    Steroids 66:817-20. 2001
  10. ncbi request reprint Increase of endothelial nitric oxide synthase and endothelin-1 mRNA expression in human placenta during gestation
    J Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Loschgestrasse 15, 91054, Erlangen, Germany
    Eur J Obstet Gynecol Reprod Biol 97:163-7. 2001

Collaborators

  • H Christiansen
  • M Bettendorf
  • B P Hauffa
  • Ina Knerr
  • B Doeker
  • Bernhard Brüne
  • J Dotsch
  • Jorg Dotsch
  • W Rascher
  • Wolfgang Rascher
  • J Hanze
  • Udo Meissner
  • Jörg Dösch
  • H G Dorr
  • K Zepf
  • R Repp
  • W Kiess
  • M Kirschbaum
  • Helmuth G Dörr
  • E Schoof
  • K Dittrich
  • K Dumke
  • Ellen Schoof
  • Harald O Schocklmann
  • P Opherk
  • Reinald Repp
  • N Hogen
  • W G Sippell
  • G K Stalla
  • S Schellmoser
  • Z Nyul
  • N Albers
  • T Siebler
  • H Willgerodt
  • F Lampert
  • W Andler
  • S Parida
  • R Holl
  • U Heinrich
  • S Demirakca
  • W Foerster
  • B Gohlke
  • K D Nusken

Detail Information

Publications15

  1. ncbi request reprint Leptin and neuropeptide Y gene expression in human placenta: ontogeny and evidence for similarities to hypothalamic regulation
    J Dotsch
    Universitätsklinik für Kinder und Jugendliche, Erlangen, Germany
    J Clin Endocrinol Metab 84:2755-8. 1999
    ..Our data suggest an increase of placental leptin production with gestational age. In patients with preeclampsia, elevated leptin expression goes along with suppressed NPY expression. This resembles hypothalamic regulation...
  2. ncbi request reprint Leptin-induced weight loss is not solely mediated by anorexia
    Jorg Dotsch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
    Eur J Endocrinol 148:11-2. 2003
  3. ncbi request reprint Graves disease in childhood: a review of the options for diagnosis and treatment
    Jorg Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Erlangen, Germany
    Paediatr Drugs 5:95-102. 2003
    ..Compared with the surgical approach, success rates are lower, particularly if low doses of radioiodine are used. In general, adverse effects are less prevalent than in patients who have undergone surgery...
  4. ncbi request reprint The role of 11beta-hydroxysteroid dehydrogenase activity in the metabolic syndrome: lessons learned from the animal model
    Jorg Dotsch
    Klinik fur Kinder und Jugendliche, Loschgestr 15, 91054 Erlangen, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
    Eur J Endocrinol 146:603-5. 2002
  5. ncbi request reprint Nitric oxide increases adrenomedullin receptor function in rat mesangial cells
    Jorg Dotsch
    Klinik fur Kinder und Jugendliche, and Medizinische Klinik IV, Friedrich Alexander University Erlangen, Erlangen, Germany
    Kidney Int 61:1707-13. 2002
    ..In contrast, nitric oxide (NO) is capable of exerting both cytoprotective and cytotoxic actions. It was the objective of the present study to examine whether NO stimulates the ADM system...
  6. ncbi request reprint Diagnostic and scientific applications of TaqMan real-time PCR in neuroblastomas
    J Dotsch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander University, Erlangen, Loschgestrasse 15 91054 Erlangen, Germany
    Expert Rev Mol Diagn 1:233-8. 2001
    ..The combination with single cell picking in the neuroblastoma tissue may be a future target of the application of real-time PCR...
  7. ncbi request reprint Nitric oxide stimulates adrenomedullin secretion and gene expression in endothelial cells
    J Dotsch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander Universitat Erlangen Nurnberg, Erlangen, Deutschland
    Pharmacology 64:135-9. 2002
    ..Similar results were obtained by both quantitative PCR and Northern blot. Thus, NO donor exposure in vitro increases both adrenomedullin secretion and mRNA expression in a dose-dependent manner...
  8. ncbi request reprint Unmasking of childhood hypothyroidism by disseminated xanthomas
    J Dotsch
    Universitätsklinik für Kinder und Jugendliche, Erlangen, Erlagen, Germany
    Pediatrics 108:E96. 2001
    ..For the first time, this case depicts disseminated xanthomas of the skin as the presenting complaint of severe hypothyroidism. hyperlipidemia, hypothyroidism, xanthoma...
  9. ncbi request reprint Effect of glucocorticoid excess on the cortisol/cortisone ratio
    J Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Loschgestr 15, D 91054 Erlangen, Germany
    Steroids 66:817-20. 2001
    ..It was the objective of the present study to examine the impact of different forms of glucocorticoid excess on the cortisol/cortisone ratio and to differentiate their role in the genesis of hypertension...
  10. ncbi request reprint Increase of endothelial nitric oxide synthase and endothelin-1 mRNA expression in human placenta during gestation
    J Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Loschgestrasse 15, 91054, Erlangen, Germany
    Eur J Obstet Gynecol Reprod Biol 97:163-7. 2001
    ..To investigate the maturation of the paracrine system's endothelial nitric oxide synthase (eNOS), inducible NOS (iNOS), endothelin-1 (ET-1) and adrenomedullin (AM) in human placenta during the 2nd and 3rd trimester of pregnancy...
  11. ncbi request reprint Case of XXXXY syndrome. Development throughout adolescence and endocrine aspects
    J Dotsch
    Department of Pediatrics, Friedrich Alexander University Erlangen, Germany
    Horm Res 53:154-6. 2000
    ..The patient was started on testosterone replacement therapy. This case is reported to underline the need for thorough endocrinological follow-up examinations in males with X polysomies...
  12. ncbi request reprint Gene expression of neuronal nitric oxide synthase and adrenomedullin in human neuroblastoma using real-time PCR
    J Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Erlangen, Germany
    Int J Cancer 88:172-5. 2000
    ..In conclusion, TaqMan real-time PCR appears to be a reliable method to quantify gene expression in neuroblastomas. Adrenomedullin mRNA in neuroblastoma is linked to tumor differentiation but not to prognostic markers...
  13. ncbi request reprint Diagnosis and management of juvenile hyperthyroidism in Germany: a retrospective multicenter study
    J Dotsch
    Department of Pediatrics, University of Erlangen Nurnberg, Germany
    J Pediatr Endocrinol Metab 13:879-85. 2000
    ..Management principles of the participating centers were heterogeneous. As a consequence, prospective multicenter studies are urgently needed to establish clear standards for the diagnosis and therapy of childhood hyperthyroidism...
  14. ncbi request reprint Recovery from withdrawal of inhaled nitric oxide and kinetics of nitric oxide-induced inhibition of nitric oxide synthase activity in vitro
    J Dotsch
    Department of Pediatrics, Friedrich Alexander University of Erlangen Nurnberg, Germany
    Intensive Care Med 26:330-5. 2000
    ..To examine the kinetics of successful nitric oxide (NO) withdrawal in vivo and in vitro...
  15. ncbi request reprint Prolonged lifespan by defective insulin signalling?
    Jörg Dösch
    Klinik fur Kinder und Jugendliche, Friedrich Alexander University Erlangen, Loschgestrasse 15D, 91054 Erlangen, Germany
    Eur J Endocrinol 148:489-90. 2003