Dana S Hardin

Summary

Publications

  1. ncbi Growth hormone treatment improves growth and clinical status in prepubertal children with cystic fibrosis: results of a multicenter randomized controlled trial
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Texas 75390, USA
    J Clin Endocrinol Metab 91:4925-9. 2006
  2. ncbi Treatment of type 2 diabetes mellitus in children and adolescents
    Mohammad I Zuhri-Yafi
    Department of Pediatrics, The University of Texas Medical School Houston, 77030, USA
    J Pediatr Endocrinol Metab 15:541-6. 2002
  3. ncbi Growth hormone treatment enhances nutrition and growth in children with cystic fibrosis receiving enteral nutrition
    Dana S Hardin
    University of Texas Southwestern Medical School, Department of Pediatrics, Dallas 75390 9063, USA
    J Pediatr 146:324-8. 2005
  4. ncbi Growth hormone improves protein catabolism and growth in prepubertal children with HIV infection
    Dana S Hardin
    University of Texas South western Medical School, Dallas, TX, USA
    Clin Endocrinol (Oxf) 63:259-62. 2005
  5. ncbi Current prescribing practices and opinions about growth hormone therapy: results of a nationwide survey of paediatric endocrinologists
    Dana S Hardin
    Ohio State University, Columbus, OH 43205, USA
    Clin Endocrinol (Oxf) 66:85-94. 2007
  6. ncbi A retrospective study of growth hormone use in adolescents with cystic fibrosis
    Dana S Hardin
    Department of Pediatrics, University of Texas South western Medical School, Dallas, TX 75390 9063, USA
    Clin Endocrinol (Oxf) 62:560-6. 2005
  7. ncbi Insulin-like growth factor-I levels predict weight, height and protein catabolism in children and adolescents with cystic fibrosis
    Michael Switzer
    Department of Pediatrics, Nationwide Children s Hospital, Ohio State University, Columbus, OH 43205, USA
    J Pediatr Endocrinol Metab 22:417-24. 2009
  8. ncbi Growth hormone improves bone mineral content in children with cystic fibrosis
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Houston, TX, USA
    J Pediatr Endocrinol Metab 18:589-95. 2005
  9. ncbi Protease inhibitor therapy improves protein catabolism in prepubertal children with HIV infection
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Houston 77030, USA
    J Pediatr Endocrinol Metab 17:321-5. 2004
  10. ncbi Insulin resistance in Hispanic large-for-gestational-age neonates at birth
    Jennifer Shine Dyer
    Department of Pediatrics, Division of Endocrinology, The Ohio State University, 700 Children s Drive, W322, Columbus, Ohio 43205, USA
    J Clin Endocrinol Metab 92:3836-43. 2007

Detail Information

Publications24

  1. ncbi Growth hormone treatment improves growth and clinical status in prepubertal children with cystic fibrosis: results of a multicenter randomized controlled trial
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Texas 75390, USA
    J Clin Endocrinol Metab 91:4925-9. 2006
    ....
  2. ncbi Treatment of type 2 diabetes mellitus in children and adolescents
    Mohammad I Zuhri-Yafi
    Department of Pediatrics, The University of Texas Medical School Houston, 77030, USA
    J Pediatr Endocrinol Metab 15:541-6. 2002
    ..To study possible treatment modalities for type 2 diabetes mellitus (T2DM) in children and adolescents...
  3. ncbi Growth hormone treatment enhances nutrition and growth in children with cystic fibrosis receiving enteral nutrition
    Dana S Hardin
    University of Texas Southwestern Medical School, Department of Pediatrics, Dallas 75390 9063, USA
    J Pediatr 146:324-8. 2005
    ..This study evaluates the hypothesis that adjunctive growth hormone (GH) therapy augments the growth response to nutritional supplementation...
  4. ncbi Growth hormone improves protein catabolism and growth in prepubertal children with HIV infection
    Dana S Hardin
    University of Texas South western Medical School, Dallas, TX, USA
    Clin Endocrinol (Oxf) 63:259-62. 2005
    ..We undertook this study to test the hypothesis that human recombinant GH would improve linear height in HIV-infected children. Our second goal was to determine if GH could reverse protein catabolism in HIV-infected children...
  5. ncbi Current prescribing practices and opinions about growth hormone therapy: results of a nationwide survey of paediatric endocrinologists
    Dana S Hardin
    Ohio State University, Columbus, OH 43205, USA
    Clin Endocrinol (Oxf) 66:85-94. 2007
    ..The purpose of this study was to summarize prevailing attitudes about GH diagnosis and treatment among paediatric endocrinologists...
  6. ncbi A retrospective study of growth hormone use in adolescents with cystic fibrosis
    Dana S Hardin
    Department of Pediatrics, University of Texas South western Medical School, Dallas, TX 75390 9063, USA
    Clin Endocrinol (Oxf) 62:560-6. 2005
    ..Studies of growth hormone (GH) effectiveness in prepubertal children with cystic fibrosis (CF) have been published previously. We present a retrospective study of GH treatment in adolescents with CF...
  7. ncbi Insulin-like growth factor-I levels predict weight, height and protein catabolism in children and adolescents with cystic fibrosis
    Michael Switzer
    Department of Pediatrics, Nationwide Children s Hospital, Ohio State University, Columbus, OH 43205, USA
    J Pediatr Endocrinol Metab 22:417-24. 2009
    ..These results suggest a strong correlation between IGF-I and height, weight and protein catabolism and emphasize the need to normalize IGF-I levels in children with cystic fibrosis...
  8. ncbi Growth hormone improves bone mineral content in children with cystic fibrosis
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Houston, TX, USA
    J Pediatr Endocrinol Metab 18:589-95. 2005
    ..Our second aim was to evaluate the effect of one year of treatment with human recombinant growth hormone (GH) on total body BMC...
  9. ncbi Protease inhibitor therapy improves protein catabolism in prepubertal children with HIV infection
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Houston 77030, USA
    J Pediatr Endocrinol Metab 17:321-5. 2004
    ..One action of these drugs is that of lowering the viral burden, and several studies suggest that these drugs result in increased growth and weight velocity. Our second aim was to determine whether PI therapy improves protein catabolism...
  10. ncbi Insulin resistance in Hispanic large-for-gestational-age neonates at birth
    Jennifer Shine Dyer
    Department of Pediatrics, Division of Endocrinology, The Ohio State University, 700 Children s Drive, W322, Columbus, Ohio 43205, USA
    J Clin Endocrinol Metab 92:3836-43. 2007
    ..Although Hispanic youth have been shown to have a high prevalence of metabolic syndrome, it is unknown whether metabolic abnormalities and a predisposition for glucose intolerance are present at birth...
  11. ncbi GH improves growth and clinical status in children with cystic fibrosis -- a review of published studies
    Dana S Hardin
    University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard G2 220, Dallas, TX 75390 9063, USA
    Eur J Endocrinol 151:S81-5. 2004
    ..To date significant side effects, including glucose intolerance, have not been reported. Thus mounting evidence suggests that human recombinant GH provides safe and effective therapy in children with CF...
  12. doi Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir
    Anthony J Busti
    Texas Tech University Health Sciences Center School of Pharmacy, Dallas, Texas, USA
    J Investig Med 56:539-44. 2008
    ..However, its effects on insulin sensitivity have not been elucidated. We conducted this study to test the hypothesis that ATV improves insulin resistance and dyslipidemia...
  13. ncbi The metabolic effects of pregnancy in cystic fibrosis
    Dana S Hardin
    University of Texas Southwestern Medical Center, Dallas, Texas 75093 9063, USA
    Obstet Gynecol 106:367-75. 2005
    ..Our purpose was to determine glucose tolerance in pregnant women with cystic fibrosis (CF) and to relate glucose tolerance to insulin sensitivity, hepatic glucose production, and protein turnover...
  14. ncbi Growth hormone normalizes pubertal onset in children with cystic fibrosis
    Mark Vanderwel
    University of Texas Southwestern Medical School, Division of Pediatric Endocrinology, Dallas, USA
    J Pediatr Endocrinol Metab 19:237-44. 2006
    ..Testicular size progression was not accelerated in pubertal boys treated with GH. CONCLUSION: GH treatment normalizes pubertal onset in prepubertal children with CF...
  15. ncbi Impact of race/ethnicity on efficacy and safety of two starter insulin regimens in patients with type 2 diabetes: a posthoc analysis of the DURABLE trial
    Jaime A Davidson
    University of Texas Southwestern Medical Center, Dallas, USA
    Ethn Dis 23:393-400. 2013
    ..To explore the impact of race/ethnicity on efficacy and safety of twice-daily insulin lispro mix 75/25 (LM75/25; 75% lispro protamine suspension, 25% insulin lispro) and once daily insulin glargine (GL)...
  16. ncbi Statement 6: patients who are unresponsive to GH therapy should be given a trial of IGF-I
    Dana S Hardin
    Division of Endocrinology, Metabolism and Diabetes, Department of Pediatrics, Columbus Children s Hospital, Ohio State University, Columbus, Ohio, USA
    Pediatr Endocrinol Rev 5:857-60. 2008
  17. ncbi Growth problems and growth hormone treatment in children with cystic fibrosis
    Dana S Hardin
    Department of Pediatrics, University of Texas Southwestern Medical School, Dallas 75390 9063, USA
    J Pediatr Endocrinol Metab 15:731-5. 2002
    ..A large multicenter trial is currently underway to assess the effect of long-term therapy with GH on the quality of life and pulmonary status...
  18. ncbi Analysis of gluconeogenic pathways in vivo by distribution of 2H in plasma glucose: comparison of nuclear magnetic resonance and mass spectrometry
    Shawn C Burgess
    The Mary Nell and Ralph B Rogers Magnetic Resonance Center, Department of Radiology, University of Texas Southwestern Medical Center, 5801 Forest Park Road, Dallas, TX 75235 9085, USA
    Anal Biochem 318:321-4. 2003
  19. ncbi Twenty years of recombinant human growth hormone in children: relevance to pediatric care providers
    Dana S Hardin
    Ohio State University and Columbus Children s Hospital, Columbus, OH 43205, USA
    Clin Pediatr (Phila) 46:279-86. 2007
    ....
  20. doi A review of the management of two common clinical problems found in patients with cystic fibrosis: cystic fibrosis-related diabetes and poor growth
    Dana S Hardin
    Division of Pediatric Endocrinology, Columbus Children s Hospital, Ohio State University, Columbus, Ohio, USA
    Horm Res 68:113-6. 2007
    ..Recombinant human growth hormone (rhGH) is being explored in this patient population; studies overall show improvements in height and weight, without development of glucose intolerance...
  21. ncbi Update of guidelines for the use of growth hormone in children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee
    Thomas A Wilson
    Division of Pediatric Endocrinology, State University of New York at Stony Brook, Stony Brook, NY 11794 8111, USA
    J Pediatr 143:415-21. 2003
  22. doi Elevated gluconeogenesis and lack of suppression by insulin contribute to cystic fibrosis-related diabetes
    Dana S Hardin
    Nationwide Children s Hospital, The Ohio State University, Columbus, OH 43205 2696, USA
    J Investig Med 56:567-73. 2008
    ..Gluconeogenesis correlated with protein breakdown. These studies suggest that high HGP in CF is mostly from elevated rates of GNG and that resistance to insulin's suppression of GNG may contribute to abnormal glucose tolerance in CF...
  23. ncbi Growth hormone in cystic fibrosis
    Dana S Hardin
    The Ohio State University, Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Pediatr Endocrinol Metab 21:727-8. 2008
  24. ncbi Guide to bone health and disease in cystic fibrosis
    Robert M Aris
    CB 7020, 4131 Bioinformatics, University of North Carolina, Chapel Hill, North Carolina 27599 7524, USA
    J Clin Endocrinol Metab 90:1888-96. 2005
    ..The goal of this conference was to develop practice guidelines for optimizing bone health in patients with CF...