Hamdi K Hamdi

Summary

Publications

  1. ncbi Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration
    Hamdi K Hamdi
    Department of Surgery, Ophthalmology Research Laboratories, Burns and Allen Research Institute, Cedars Sinai Medical Center, UCLA Medical School Affiliate, 90048, USA
    Biochem Biophys Res Commun 295:668-72. 2002
  2. ncbi Effects of tenascin-C on normal and diabetic retinal endothelial cells in culture
    Raquel Castellon
    Ophthalmology Research Laboratories, Burns and Allen Research Institute, Cedars Sinai Medical Center, University of California Los Angeles Medical School Affiliate, Los Angeles, California, USA
    Invest Ophthalmol Vis Sci 43:2758-66. 2002
  3. ncbi Age-related macular degeneration: a new viewpoint
    Hamdi K Hamdi
    Ophthalmology Research Laboratories, University of California, Irvine, Medical Center, 101 The City Drive, Ophthalmology Research, Building 55, Room 206, Orange, CA 92868, USA
    Front Biosci 8:e305-14. 2003
  4. ncbi Effects of angiogenic growth factor combinations on retinal endothelial cells
    Raquel Castellon
    Ophthalmology Research Laboratories, Burns and Allen Research Institute, Cedars Sinai Medical Center, UCLA Medical School Affiliate, Los Angeles, CA 90048, USA
    Exp Eye Res 74:523-35. 2002
  5. ncbi A genetic variant of ACE increases cell survival: a new paradigm for biology and disease
    Hamdi K Hamdi
    Department of Ophthalmology, University of California, Irvine, 101 The City Drive Bldg 55, Room 202, Orange, CA 92868, USA
    Biochem Biophys Res Commun 318:187-91. 2004
  6. ncbi Demystifying the ACE polymorphism: from genetics to biology
    Raquel Castellon
    H2RC Corporation, Orange, CA 92867, USA
    Curr Pharm Des 13:1191-8. 2007

Detail Information

Publications6

  1. ncbi Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration
    Hamdi K Hamdi
    Department of Surgery, Ophthalmology Research Laboratories, Burns and Allen Research Institute, Cedars Sinai Medical Center, UCLA Medical School Affiliate, 90048, USA
    Biochem Biophys Res Commun 295:668-72. 2002
    ..This is the first demonstration of an Alu element insertion exerting protective effects against a known human disease...
  2. ncbi Effects of tenascin-C on normal and diabetic retinal endothelial cells in culture
    Raquel Castellon
    Ophthalmology Research Laboratories, Burns and Allen Research Institute, Cedars Sinai Medical Center, University of California Los Angeles Medical School Affiliate, Los Angeles, California, USA
    Invest Ophthalmol Vis Sci 43:2758-66. 2002
    ..Because TN-C may promote neovascularization, its potential angiogenic effects were examined in vitro in normal and diabetic retinal endothelial cells (RECs)...
  3. ncbi Age-related macular degeneration: a new viewpoint
    Hamdi K Hamdi
    Ophthalmology Research Laboratories, University of California, Irvine, Medical Center, 101 The City Drive, Ophthalmology Research, Building 55, Room 206, Orange, CA 92868, USA
    Front Biosci 8:e305-14. 2003
    ..Given these recent genetic associations, we should examine possible common pathways in diseases of age and their interaction with human genetic polymorphisms...
  4. ncbi Effects of angiogenic growth factor combinations on retinal endothelial cells
    Raquel Castellon
    Ophthalmology Research Laboratories, Burns and Allen Research Institute, Cedars Sinai Medical Center, UCLA Medical School Affiliate, Los Angeles, CA 90048, USA
    Exp Eye Res 74:523-35. 2002
    ..Their effects, however, can be greatly augmented by other growth factors that alone exert little or no action. Therefore, diabetic retinal neovascularization may result from the additive or synergistic action of several growth factors...
  5. ncbi A genetic variant of ACE increases cell survival: a new paradigm for biology and disease
    Hamdi K Hamdi
    Department of Ophthalmology, University of California, Irvine, 101 The City Drive Bldg 55, Room 202, Orange, CA 92868, USA
    Biochem Biophys Res Commun 318:187-91. 2004
    ..These results provide the first evidence of a functional role for a naturally occurring polymorphism, having broad implications for human biology, longevity, and disease...
  6. ncbi Demystifying the ACE polymorphism: from genetics to biology
    Raquel Castellon
    H2RC Corporation, Orange, CA 92867, USA
    Curr Pharm Des 13:1191-8. 2007
    ..We also provide a model to understand its role in biology and disease at the organism and population levels...