Khaled Hamden

Summary

Publications

  1. ncbi request reprint Therapeutic effect of phytoecdysteroids rich extract from Ajuga iva on alloxan induced diabetic rats liver, kidney and pancreas
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Sciences, University of Sfax, Sfax, Tunisia
    Biofactors 33:165-75. 2008
  2. ncbi request reprint 1Alpha,25 dihydroxyvitamin D3: therapeutic and preventive effects against oxidative stress, hepatic, pancreatic and renal injury in alloxan-induced diabetes in rats
    Khaled Hamden
    Laboratry of Animal Ecophysiology, Department of Life Science, Faculty of Science, University of Sfax, Tunisia
    J Nutr Sci Vitaminol (Tokyo) 55:215-22. 2009
  3. pmc Hypoglycemic and antilipidemic properties of kombucha tea in alloxan-induced diabetic rats
    Ahmed Aloulou
    Laboratory of Biochemistry and Enzymatic Engineering of Lipases, National School of Engineers of Sfax, University of Sfax, Tunisia
    BMC Complement Altern Med 12:63. 2012
  4. ncbi request reprint Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17β-estradiol level in induction of acute oxidative stress
    Mohamed Ali Medali Boujbiha
    Laboratory of Animal Ecophysiology, Faculty of Sciences, University of Sfax, P O Box 802, 3018 Sfax, Tunisia
    Biol Trace Elem Res 142:598-610. 2011
  5. doi request reprint Combined vitamins (C and E) and insulin improve oxidative stress and pancreatic and hepatic injury in alloxan diabetic rats
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Sciences, University of Sfax, P O Box 802, 3018 Sfax, Tunisia
    Biomed Pharmacother 63:95-9. 2009
  6. doi request reprint Antioxidant effect of nondigestible levan and its impact on cardiovascular disease and atherosclerosis
    Imen Dahech
    Biochemistry Laboratory, Faculty of Sciences of Sfax, Sfax, Tunisia
    Int J Biol Macromol 58:281-6. 2013
  7. doi request reprint Hypolipidemic effect of diet supplementation with bacterial levan in cholesterol-fed rats
    Karima Srih Belghith
    Biochemistry Laboratory, Faculty of Sciences of Sfax, Sfax, Tunisia
    Int J Biol Macromol 50:1070-4. 2012
  8. doi request reprint Protective effects of estrogens and caloric restriction during aging on various rat testis parameters
    Khaled Hamden
    Department of Animal Ecophysiology, Faculty of Sciences, University of Sfax, PB 802, Sfax 3018, Tunisia
    Asian J Androl 10:837-45. 2008
  9. doi request reprint Therapeutic effects of soy isoflavones on α-amylase activity, insulin deficiency, liver-kidney function and metabolic disorders in diabetic rats
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Science, University of Sfax, Sfax 3052, Tunisia
    Nat Prod Res 25:244-55. 2011
  10. ncbi request reprint Inhibition of key enzymes related to diabetes and hypertension by Eugenol in vitro and in alloxan-induced diabetic rats
    Kais Mnafgui
    Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax, University of Sfax, P O Box 95, Sfax 3052, Tunisia
    Arch Physiol Biochem 119:225-33. 2013

Collaborators

  • Imen Dahech
  • Ahmed Aloulou
  • Hamden Khaled
  • Serge Carreau
  • Kais Mnafgui
  • Abdelfattah Elfeki
  • Noureddine Allouche
  • Fatma Derbali
  • Sadok Slama
  • Naourez Ktari
  • Salwa Hamzaoui
  • Mbarek Nasri
  • Sahla Belhadj
  • Mouna Kchaou
  • Hichem Ben Salah
  • Karima Srih Belghith
  • Mohamed Ali Medali Boujbiha
  • Fadhel Guermazi
  • Ali Bouslama
  • Asma Omezzine
  • Abdelfattah El Feki
  • Mohamed Ali Boujbiha
  • Adel Ben Salem
  • Amal Derbali
  • Moncef Nasri
  • Maxime Mourer
  • Tahia Boudaouara
  • Intidhar Bkhairia
  • Aïda Ben Hadj
  • Rim Nasri
  • Olfa Hentati
  • Jean Bernard Regnouf-de-Vains
  • Mohamed Kossentini
  • Fatima Kaanich
  • Hafedh Mejdoub
  • Hafedh Belghith
  • Abdelfattah Feki
  • Abdelaziz Kammoun

Detail Information

Publications26

  1. ncbi request reprint Therapeutic effect of phytoecdysteroids rich extract from Ajuga iva on alloxan induced diabetic rats liver, kidney and pancreas
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Sciences, University of Sfax, Sfax, Tunisia
    Biofactors 33:165-75. 2008
    ..In conclusion, Ajuga iva phytoecdysteroids supplements seem to be beneficial for correcting the hyperglycemia and preventing diabetic complications in liver, pancreas and kidneys...
  2. ncbi request reprint 1Alpha,25 dihydroxyvitamin D3: therapeutic and preventive effects against oxidative stress, hepatic, pancreatic and renal injury in alloxan-induced diabetes in rats
    Khaled Hamden
    Laboratry of Animal Ecophysiology, Department of Life Science, Faculty of Science, University of Sfax, Tunisia
    J Nutr Sci Vitaminol (Tokyo) 55:215-22. 2009
    ....
  3. pmc Hypoglycemic and antilipidemic properties of kombucha tea in alloxan-induced diabetic rats
    Ahmed Aloulou
    Laboratory of Biochemistry and Enzymatic Engineering of Lipases, National School of Engineers of Sfax, University of Sfax, Tunisia
    BMC Complement Altern Med 12:63. 2012
    ..The present study aimed to investigate and compare the hypoglycemic and antilipidemic effects of kombucha and black tea, two natural drinks commonly consumed around the world, in surviving diabetic rats...
  4. ncbi request reprint Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17β-estradiol level in induction of acute oxidative stress
    Mohamed Ali Medali Boujbiha
    Laboratory of Animal Ecophysiology, Faculty of Sciences, University of Sfax, P O Box 802, 3018 Sfax, Tunisia
    Biol Trace Elem Res 142:598-610. 2011
    ....
  5. doi request reprint Combined vitamins (C and E) and insulin improve oxidative stress and pancreatic and hepatic injury in alloxan diabetic rats
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Sciences, University of Sfax, P O Box 802, 3018 Sfax, Tunisia
    Biomed Pharmacother 63:95-9. 2009
    ..05). In diabetic rats treated with insulin or with combined vitamins (C and E), an ameliorative effect was observed. This amelioration was more pronounced in the group of rats treated with combined vitamins (C and E)...
  6. doi request reprint Antioxidant effect of nondigestible levan and its impact on cardiovascular disease and atherosclerosis
    Imen Dahech
    Biochemistry Laboratory, Faculty of Sciences of Sfax, Sfax, Tunisia
    Int J Biol Macromol 58:281-6. 2013
    ..33% and 64%, respectively. Thus may have potential antioxidant effects and could protect against oxidative stress linked atherosclerosis...
  7. doi request reprint Hypolipidemic effect of diet supplementation with bacterial levan in cholesterol-fed rats
    Karima Srih Belghith
    Biochemistry Laboratory, Faculty of Sciences of Sfax, Sfax, Tunisia
    Int J Biol Macromol 50:1070-4. 2012
    ..Levan could protect against oxidative stress linked atherosclerosis and decrease the atherogenic index...
  8. doi request reprint Protective effects of estrogens and caloric restriction during aging on various rat testis parameters
    Khaled Hamden
    Department of Animal Ecophysiology, Faculty of Sciences, University of Sfax, PB 802, Sfax 3018, Tunisia
    Asian J Androl 10:837-45. 2008
    ..To investigate the effects of 17beta-estradiol (E2), Peganum harmala extract (PHE) and caloric restriction (CR) on various testis parameters during aging...
  9. doi request reprint Therapeutic effects of soy isoflavones on α-amylase activity, insulin deficiency, liver-kidney function and metabolic disorders in diabetic rats
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Science, University of Sfax, Sfax 3052, Tunisia
    Nat Prod Res 25:244-55. 2011
    ....
  10. ncbi request reprint Inhibition of key enzymes related to diabetes and hypertension by Eugenol in vitro and in alloxan-induced diabetic rats
    Kais Mnafgui
    Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax, University of Sfax, P O Box 95, Sfax 3052, Tunisia
    Arch Physiol Biochem 119:225-33. 2013
    ....
  11. doi request reprint Inhibitory activities of Ulva lactuca polysaccharides on digestive enzymes related to diabetes and obesity
    Sahla Belhadj
    Laboratory of Animal Ecophysiology, University of Sfax, Faculty of Sciences of Sfax, PO Box 95, Sfax, Tunisia
    Arch Physiol Biochem 119:81-7. 2013
    ....
  12. doi request reprint Potential protective effect on key steroidogenesis and metabolic enzymes and sperm abnormalities by fenugreek steroids in testis and epididymis of surviving diabetic rats
    Khaled Hamden
    Laboratory of Animal Ecophysiology, Faculty of Science of Sfax, PO Box 95, Sfax 3052, Tunisia
    Arch Physiol Biochem 116:146-55. 2010
    ..Above all, the potential protective action of reproductive systems was approved by the histological study of testis and epididymis...
  13. doi request reprint Antidiabetic activity of levan polysaccharide in alloxan-induced diabetic rats
    Imen Dahech
    Biochemistry Laboratory, Faculty of Sciences of Sfax, Sfax, Tunisia
    Int J Biol Macromol 49:742-6. 2011
    ....
  14. doi request reprint Hypoglycemic and antioxidant effects of phenolic extracts and purified hydroxytyrosol from olive mill waste in vitro and in rats
    Khaled Hamden
    Animal Ecophysiology, Faculty of Sciences, Sfax, Tunisia
    Chem Biol Interact 180:421-32. 2009
    ....
  15. pmc Inhibitory potential of omega-3 fatty and fenugreek essential oil on key enzymes of carbohydrate-digestion and hypertension in diabetes rats
    Khaled Hamden
    Biotechnology High School of Sfax ISBS, University of Sfax, P O Box 261, Sfax 3038, Tunisia
    Lipids Health Dis 10:226. 2011
    ..Treatment of diabetes and its related diseases can be achieved by inhibiting key digestives enzymes-related to starch digestion secreted by pancreas...
  16. doi request reprint Immunomodulatory, beta-cell, and neuroprotective actions of fenugreek oil from alloxan-induced diabetes
    Khaled Hamden
    Animal Ecophysiology Laboratory, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia
    Immunopharmacol Immunotoxicol 32:437-45. 2010
    ....
  17. doi request reprint Experimental diabetes treated with trigonelline: effect on key enzymes related to diabetes and hypertension, β-cell and liver function
    Khaled Hamden
    Biotechnology High School of Sfax ISBS, University of Sfax, Sfax, Tunisia
    Mol Cell Biochem 381:85-94. 2013
    ..It is therefore suggested that Trig may be a potential agent for the treatment of type 2 diabetes. ..
  18. doi request reprint Inhibition of carbohydrate and lipid digestive enzymes activities by Zygophyllum album extracts: effect on blood and pancreas inflammatory biomarkers in alloxan-induced diabetic rats
    Kais Mnafgui
    Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax, University of Sfax, P O Box 95, Sfax, 3052, Tunisia
    J Physiol Biochem 70:93-106. 2014
    ..Z. album showed a prominent antidiabetic effect via inhibition of carbohydrate and lipid digestive enzymes and ameliorated the inflammation and the disturbance of hematological biomarkers in diabetes...
  19. ncbi request reprint Hypoglycemic and hypolipidemic effects of protein hydrolysates from zebra blenny (Salaria basilisca) in alloxan-induced diabetic rats
    Naourez Ktari
    Laboratory of Enzyme Engineering and Microbiology, University of Sfax, National School of Engineering of Sfax ENIS, P O Box 1173, Sfax 3038, Tunisia
    Food Funct 4:1691-9. 2013
    ..Overall, the findings of the current study indicate that ZBPHs significantly attenuated hyperglycemia and hyperlipidemia in AIDR. ..
  20. doi request reprint Positive effects of green tea on hepatic dysfunction, lipid peroxidation and antioxidant defence depletion induced by cadmium
    Khaled Hamden
    Animal Ecophysiology, Faculty of Sciences, University of Sfax, Tunisia
    Biol Res 41:331-9. 2008
    ..Thus, the oral administration of green tea, along with cadmium significantly (p < 0.05) improves cadmium-induced liver dysfunction and stress oxidant in rats' liver...
  21. ncbi request reprint Protective effects of Peganum harmala extracts on thiourea-induced diseases in adult male rat
    Khaled Hamden
    Animal Ecophysiology, Faculty of Sciences, Sfax, CHU H Bourguiba, Sfax, Tunisie, France
    J Environ Biol 29:73-7. 2008
    ..Therefore we may suggest that extracts of Peganum harmala are efficient to reduce the toxicity induced by thiourea in male rat as far as the above parameters are concerned...
  22. doi request reprint Synthesis and evaluation of 1,ω-bis(1,2,3,5-thiatriazol-5-yl)alkanes as in vitro and in vivo α-amylase and lipase inhibitors
    Salwa Hamzaoui
    Laboratoire de Chimie Appliquee, Heterocycles, Corps Gras et Polymères Faculté des Sciences de Sfax, Universite de Sfax, Sfax, Tunisia
    Arch Pharm (Weinheim) 346:321-9. 2013
    ..Overall, the findings of the current study indicate that 2d exhibits attractive properties and can, therefore, be considered for future application in the development of anti-diabetic and hypolipidemic drugs...
  23. doi request reprint Testicular toxicity in mercuric chloride treated rats: association with oxidative stress
    Mohamed Ali Boujbiha
    Laboratory of Ecophysiology of Animals, Faculty of Sciences, 3018 Sfax, BP 802, Tunisia
    Reprod Toxicol 28:81-9. 2009
    ....
  24. doi request reprint Hyperglycaemia, stress oxidant, liver dysfunction and histological changes in diabetic male rat pancreas and liver: protective effect of 17 beta-estradiol
    Khaled Hamden
    Animal Ecophysiology, Faculty of Sciences, Sfax, Tunisia
    Steroids 73:495-501. 2008
    ..Moreover, 17 beta-estradiol treatment in diabetic rats protects against alloxan-induced pancreatic beta-cells and hepatic cells damages...
  25. pmc Inhibition of key digestive enzymes related to diabetes and hyperlipidemia and protection of liver-kidney functions by trigonelline in diabetic rats
    Khaled Hamden
    Biotechnology High School of Sfax ISBS, University of Sfax, Soukra Km 45 PO Box 261, Sfax 3038, Tunisia
    Sci Pharm 81:233-46. 2013
    ....
  26. pmc Inhibitory Activities of Zygophyllum album: A Natural Weight-Lowering Plant on Key Enzymes in High-Fat Diet-Fed Rats
    Kais Mnafgui
    Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax, University of Sfax, P O Box 95, Sfax 3000, Tunisia Laboratory of Chemistry of Natural Products, Faculty of Sciences of Sfax, B P 1171, Sfax 3000, Tunisia
    Evid Based Complement Alternat Med 2012:620384. 2012
    ..In conclusion, these results showed a strong antihypelipidemic effect of EZA which can delay the occurrence of dislipidemia and hypertension...