Ioannis Halikias



  1. request reprint
    Sakorafas G, Stafyla V, Tsiotos G. Biliary peritonitis due to fistulous tract rupture following a T-tube removal. N Z Med J. 2005;118:U1522 pubmed
    ..A Nelaton catheter was inserted through this opening and advanced toward the biliary tree and secured in place by a suture ligature. Postoperative course was uneventful. ..
  2. Sakorafas G, Smyrniotis V, Reid Lombardo K, Sarr M. Primary pancreatic cystic neoplasms revisited. Part III. Intraductal papillary mucinous neoplasms. Surg Oncol. 2011;20:e109-18 pubmed publisher
    ..Recurrences following surgical resection can be observed, especially in patients with multifocal disease or in the presence of underlying malignancy. ..
  3. Sakorafas G, Smyrniotis V, Reid Lombardo K, Sarr M. Primary pancreatic cystic neoplasms revisited: part II. Mucinous cystic neoplasms. Surg Oncol. 2011;20:e93-101 pubmed publisher
    ..Since MCNs have malignant potential, surgical resection is the treatment of choice. ..
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    Sakorafas G, Sarr M, Van De Velde C, Peros G. Intraductal papillary mucinous neoplasms of the pancreas: a surgical perspective. Surg Oncol. 2005;14:155-78 pubmed
    ..However, invasive IPMNs behave quite similar to ductal adenocarcinoma of the pancreas when analyzed stage-by-stage, with a slightly better prognosis; however, even after an R0 resection, recurrence is common. ..
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    Sakorafas G, Tsiotou A. Etiology and pathogenesis of acute pancreatitis: current concepts. J Clin Gastroenterol. 2000;30:343-56 pubmed
    ..interleukin [IL]-1, IL-6, IL-8, tumor necrosis factor-alpha, platelet activating factor) are considered to be principal mediators in the transformation of acute pancreatitis from a local inflammatory process into a multiorgan illness. ..
  6. Sakorafas G, Friess H, Peros G. The genetic basis of hereditary medullary thyroid cancer: clinical implications for the surgeon, with a particular emphasis on the role of prophylactic thyroidectomy. Endocr Relat Cancer. 2008;15:871-84 pubmed publisher
    ..Hereditary MTC is a model of genetically determined cancer in which both diagnostic and therapeutic strategies rely on the identification of specific mutations. ..
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    Sakorafas G, Kokoropoulos P, Lappas C, Sampanis D, Smyrniotis V. External branch of the superior laryngeal nerve: applied surgical anatomy and implications in thyroid surgery. Am Surg. 2012;78:986-91 pubmed
    ..An in-depth knowledge of the surgical anatomy of the EBSLN is therefore required from the part of the operating surgeon to protect this nerve during thyroid surgery. ..
  8. Sakorafas G, Smyrniotis V, Reid Lombardo K, Sarr M. Primary pancreatic cystic neoplasms of the pancreas revisited. Part IV: rare cystic neoplasms. Surg Oncol. 2012;21:153-63 pubmed publisher
    ..Moreover, each of these unusual neoplasms has their own natural history/tumor biology and may require a different level of operative aggressiveness to obtain the optimal outcome. ..
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    Sakorafas G, Peros G. Sentinel lymph node biopsy in breast cancer: what a physician should know, a decade after its introduction in clinical practice. Eur J Cancer Care (Engl). 2007;16:318-21 pubmed
    ..The physician should be familiar with this new technique. This will allow him or her to be more actively involved in the management of breast cancer patients and to understand the available management options for these patients. ..

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  1. request reprint
    Sakorafas G, Stafyla V, Bramis C, Kotsifopoulos N, Kolettis T, Kassaras G. Incidental parathyroidectomy during thyroid surgery: an underappreciated complication of thyroidectomy. World J Surg. 2005;29:1539-43 pubmed
    ..Incidental parathyroidectomy may be considered as a potentially preventable but clinically minor complication of thyroid surgery. ..
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    Sakorafas G, Pavlakis G, Grigoriadis K. Small bowel perforation secondary to metastatic lung cancer: a case report and review of the literature. Mt Sinai J Med. 2003;70:130-2 pubmed
    ..Aggressive investigation and early surgery is the only method for providing palliation to these patients. However, morbidity and mortality remain high and the prognosis is dire. ..
  3. Sakorafas G, Mastoraki A, Lappas C, Sampanis D, Danias N, Smyrniotis V. Conservative treatment of acute appendicitis: heresy or an effective and acceptable alternative to surgery?. Eur J Gastroenterol Hepatol. 2011;23:121-7 pubmed publisher
  4. Sakorafas G, Smyrniotis V, Reid Lombardo K, Sarr M. Primary pancreatic cystic neoplasms revisited. Part I: serous cystic neoplasms. Surg Oncol. 2011;20:e84-92 pubmed publisher
    ..Conservative treatment is a reasonable option in selected patients (for example in the presence of small, asymptomatic lesions in the pancreatic head, especially in the frail or elderly patient). ..
  5. Sakorafas G, Safioleas M. Breast cancer surgery: an historical narrative. Part II. 18th and 19th centuries. Eur J Cancer Care (Engl). 2010;19:6-29 pubmed publisher
    ..Halsted was able to report a very low local recurrence rates (approximately 6%), a very important achievement given the advanced stages of the breast cancer when diagnosed in women at that time. ..
  6. Sakorafas G, Safioleas M. Breast cancer surgery: an historical narrative. Part I. From prehistoric times to Renaissance. Eur J Cancer Care (Engl). 2009;18:530-44 pubmed publisher
    ..Surgery was often 'heroic' but primitive and even inhumane by current standards. Therapeutic nihilism was the prevailing altitude regarding breast cancer, at least among the vast majority of surgeons. ..
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    Sakorafas G, Nissotakis C, Peros G. Abdominal desmoid tumors. Surg Oncol. 2007;16:131-42 pubmed
    ..Adjuvant therapy should be considered in selected cases; the role of other management options (including gene transfer therapy) is currently under intensive investigation...
  8. Sakorafas G, Peros G. Obstructing sigmoid cancer in a patient with a large, tender, non-reducible inguinal hernia: the obvious diagnosis is not always the correct one. Eur J Cancer Care (Engl). 2008;17:72-3 pubmed publisher
    ..He was operated with the presumed diagnosis of strangulated inguinal hernia. At surgery, a perforated obstructing sigmoid colon was diagnosed. A sigmoidectomy (Hartman procedure) and hernia repair (Bassini technique) was performed...
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    Sakorafas G, Stafyla V, Kassaras G. Spontaneous cyst-cutaneous fistula: an extremely rare presentation of hydatid liver cyst. Am J Surg. 2006;192:205-6 pubmed
  10. Sakorafas G, Ntavatzikos A, Konstantiadou I, Karamitopoulou E, Kavatha D, Peros G. Peritoneal tuberculosis in pregnancy mimicking advanced ovarian cancer: a plea to avoid hasty, radical and irreversible surgical decisions. Int J Infect Dis. 2009;13:e270-2 pubmed publisher
    ..The patient was successfully treated conservatively. Hasty decisions to undertake radical and irreversible surgery should be avoided; this type of surgery should be performed only after histological confirmation. ..
  11. Sakorafas G, Sampanis D, Lappas C, Papantoni E, Christodoulou S, Mastoraki A, et al. Retained surgical sponges: what the practicing clinician should know. Langenbecks Arch Surg. 2010;395:1001-7 pubmed publisher
  12. Nikou G, Toubanakis C, Moulakakis K, Pavlatos S, Kosmidis C, Mallas E, et al. Carcinoid tumors of the duodenum and the ampulla of Vater: current diagnostic and therapeutic approach in a series of 8 patients. Case series. Int J Surg. 2011;9:248-53 pubmed publisher
    ..To describe the specific characteristics of duodenal/perivaterian carcinoids and to analyze the diagnostic/therapeutic approach...
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    Sakorafas G, Sarr M. Cystic neoplasms of the pancreas; what a clinician should know. Cancer Treat Rev. 2005;31:507-35 pubmed
    ..In the absence of invasive disease, prognosis is excellent after appropriate surgery. The presence of invasive malignancy signifies a poor prognosis...
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    Sakorafas G. Nipple discharge: current diagnostic and therapeutic approaches. Cancer Treat Rev. 2001;27:275-82 pubmed
    ..e. duct-lobular segmentectomy with adequate, free margins [ideally>1cm], levels I and II axillary lymph node dissection, followed by breast irradiation)...