Dexamethasone and basic-fibroblast growth factor regulate markers of mineralization in cementoblasts in vitroSema S Hakki
Selcuk University, Faculty of Dentistry, Department of Periodontology, Konya, Turkey
J Periodontol 76:1550-8. 2005
..The aim of this study was to determine the effects of basic-fibroblast growth factor (b-FGF) and/or dexamethasone (Dex) on cementoblasts in vitro...
Osteogenic differentiation of MC3T3-E1 cells on different titanium surfacesSema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya 42079, Turkey
Biomed Mater 7:045006. 2012
..This study demonstrated that surface roughness of titanium implants has a significant effect on cellular behavior and SLG surface apparently increased gene expressions related to osteogenesis when compared to the S and the SSG surfaces...
Effects of different setting of diode laser on the mRNA expression of growth factors and type I collagen of human gingival fibroblastsSema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, 42079, Turkey
Lasers Med Sci 27:325-31. 2012
..05). The results of this study demonstrate that non-surgical laser applications modulate behavior of gingival fibroblasts inducing growth factors mRNA expressions and these applications can be used to improve periodontal wound healing...
Effects of mineral trioxide aggregate on cell survival, gene expression associated with mineralized tissues, and biomineralization of cementoblastsSema S Hakki
Faculty of Dentistry, Department of Periodontology, Selcuk University, Konya, Turkey
J Endod 35:513-9. 2009
..02 and 0.002 mg/mL. Based on these results MTA can be considered as a favorable material regarding cell-material interaction...
Boron regulates mineralized tissue-associated proteins in osteoblasts (MC3T3-E1)Sema S Hakki
Selcuk University, Faculty of Dentistry, Department of Periodontology, Konya, Turkey
J Trace Elem Med Biol 24:243-50. 2010
..1, 1, 10 and 100 ng/ml B concentrations. Results of the study suggest that at the molecular level B displays important roles on bone metabolism and may find novel usages at the regenerative medicine...
Bone morphogenetic protein-7 enhances cementoblast function in vitroSema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Periodontol 81:1663-74. 2010
..We hypothesized that BMP-7 would regulate mineralized tissue-associated genes in cementoblasts and influence the expression profile of genes associated with cementoblast extracellular matrix (ECM) and cell adhesion molecules (CAMs)...
Comparison of Er,Cr:YSGG laser and hand instrumentation on the attachment of periodontal ligament fibroblasts to periodontally diseased root surfaces: an in vitro studySema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Periodontol 81:1216-25. 2010
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Regulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases by basic fibroblast growth factor and dexamethasone in periodontal ligament cellsS S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Periodontal Res 44:794-802. 2009
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Effects of root planing procedures with hand instrument or erbium, chromium:yttrium-scandium-gallium-garnet laser irradiation on the root surfaces: a comparative scanning electron microscopy studySema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya 42079, Turkey
Lasers Med Sci 25:345-53. 2010
..It may be concluded that short pulse laser may be more suitable for the micro-morphology of the root surface. However, additional in vitro and clinical studies are necessary to clarify the success of laser in periodontal therapy...
Identification of the difference in extracellular matrix and adhesion molecules of cultured human gingival fibroblasts versus juvenile hyaline fibromatosis gingival fibroblasts using cDNA microarray analysisSema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Periodontol 76:2244-53. 2005
..The aim of this study was to understand the mechanism of gingival overgrowth in JHF, and to observe differences in the expression of genes regulating extracellular matrix organization...
Real-time cell analysis of the cytotoxicity of orthodontic mini-implants on human gingival fibroblasts and mouse osteoblastsSiddik Malkoc
Department of Orthodontics, Faculty of Dentistry, Inonu University, Malatya, Turkey
Am J Orthod Dentofacial Orthop 141:419-26. 2012
..The aim of this study was to evaluate the cytotoxic effects of orthodontic mini-implants on gingival fibroblasts and osteoblasts...
Bone sialoprotein gene transfer to periodontal ligament cells may not be sufficient to promote mineralization in vitro or in vivoSema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Periodontol 77:167-73. 2006
..In this study, we examined whether gene transfer of BSP into periodontal ligament (PDL) cells would result in an increased ability of PDL cells to promote mineralization in vitro and in vivo...
Real-time cell analysis of the cytotoxicity of the components of orthodontic acrylic materials on gingival fibroblastsFirat Ozturk
Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Inonu University, Malatya, Turkey
Am J Orthod Dentofacial Orthop 140:e243-9. 2011
..The aim of this study was to evaluate the cytotoxicity of 3 orthodontic acrylic materials and 2 manipulation methods...
Clinical, genetic, and biochemical findings in two siblings with Papillon-Lefèvre SyndromeN Arzu Cagli
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Periodontol 76:2322-9. 2005
..The failure of patients to respond to periodontal treatment is discussed in the context of these biological findings...
Investigation of matrix metalloproteinase-1--1607 1G/2G polymorphism in a Turkish population with periodontitisKemal Ustun
Oral and Dental Health Center, Selcuklu, Konya, Turkey
J Clin Periodontol 35:1013-9. 2008
..The aim of this study was to examine the association between MMP-1 -1607 1G/2G polymorphism and chronic periodontitis susceptibility in a Turkish population...
Periodontal treatment of two siblings with juvenile hyaline fibromatosisSema S Hakki
Department of Periodontology, Faculty of Dentistry, Selcuk University, Konya, Turkey
J Clin Periodontol 32:1016-21. 2005
..In this case report, periodontal status, treatment and follow-up together with histopathologic evaluation of gingival tissue specimens and mutation screening of two JHF cases are presented...
Boron enhances strength and alters mineral composition of bone in rabbits fed a high energy dietSema S Hakki
Selcuk University, Faculty of Dentistry, Department of Periodontology, Konya, Turkey
J Trace Elem Med Biol 27:148-53. 2013
..The findings indicate boron has beneficial effects on bone strength and mineral composition in rabbits fed a high energy diet...
Periodontal status in two siblings with severe congenital neutropenia: diagnosis and mutational analysis of the casesSema S Hakki
Selcuk University, Faculty of Dentistry, Department of Periodontology, Konya, Turkey
J Periodontol 76:837-44. 2005
..The disease is characterized by a maturation arrest of neutrophil precursors at the promyelocytic stage of differentiation and by extremely low levels of mature neutrophils in peripheral blood...
Severe gingival recession caused by traumatic occlusion and mucogingival stress: a case reportKemal Ustun
Konya Oral Health Center, Konya, Turkey
Eur J Dent 2:127-33. 2008
..Unless occlusal relationship was corrected, treatment of severe gingival recession will be problematic. For satisfactory periodontal treatment, early diagnosis of trauma from occlusion and its treatment is very important...