Olivares A, Jelcick A, Reinecke J, Leehy B, Haider A, Morrison M, et al
. Multimodal Regulation Orchestrates Normal and Complex Disease States in the Retina. Sci Rep. 2017;7:690 pubmed publisher
..These studies provide insight into the complex, dynamic modulation of gene networks as well as their impact on human disease, and provide novel data for the development of innovative and more effective therapeutics. ..
Olivares A, Han Y, Soto D, Flattery K, Marini J, Mollema N, et al
. The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning. Dev Biol. 2017;429:343-355 pubmed publisher
..This study supports a role for Nr2c1 in defining the biphasic period of retinal development and specifically influencing the early phase of retinal cell fate. ..
Olivares A, Althoff K, Chen G, Wu S, Morrisson M, DeAngelis M, et al
. Animal Models of Diabetic Retinopathy. Curr Diab Rep. 2017;17:93 pubmed publisher
..Currently, no model completely recapitulates the full pathophysiology of neuronal and vascular changes that occur at each stage of diabetic retinopathy; however, each model recapitulates many of the disease phenotypes. ..