Research Topics

Annakaisa Haapasalo

Summary

Publications

  1. ncbi The many substrates of presenilin/γ-secretase
    Annakaisa Haapasalo
    Institute of Clinical Medicine Neurology, University of Eastern Finland, Kuopio, Finland
    J Alzheimers Dis 25:3-28. 2011
  2. ncbi Age-related macular degeneration (AMD): Alzheimer's disease in the eye?
    Kai Kaarniranta
    Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    J Alzheimers Dis 24:615-31. 2011
  3. ncbi AMP-activated protein kinase: a potential player in Alzheimer's disease
    Antero Salminen
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    J Neurochem 118:460-74. 2011
  4. ncbi Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype
    Antero Salminen
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    Eur J Neurosci 34:3-11. 2011

Collaborators

  • Antero Salminen
  • Kai Kaarniranta
  • Mikko Hiltunen
  • Hilkka Soininen
  • Johanna Ojala

Detail Information

Publications4

  1. ncbi The many substrates of presenilin/γ-secretase
    Annakaisa Haapasalo
    Institute of Clinical Medicine Neurology, University of Eastern Finland, Kuopio, Finland
    J Alzheimers Dis 25:3-28. 2011
    ..Finally, we recapitulate the current knowledge on the possible physiological function of PS/γ-secretase-mediated cleavage of specific substrate proteins...
  2. ncbi Age-related macular degeneration (AMD): Alzheimer's disease in the eye?
    Kai Kaarniranta
    Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    J Alzheimers Dis 24:615-31. 2011
    ..However, it seems that these diseases have a different genetic background. In this review, differences and similarities of AMD and AD are thoroughly discussed...
  3. ncbi AMP-activated protein kinase: a potential player in Alzheimer's disease
    Antero Salminen
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    J Neurochem 118:460-74. 2011
    ..We will outline the potential role of AMPK function in respect to various aspects affecting AD pathogenesis...
  4. ncbi Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype
    Antero Salminen
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    Eur J Neurosci 34:3-11. 2011
    ..We will review the astroglial changes occurring during aging and emphasize that senescent astrocytes can have an important role in age-related neuroinflammation and neuronal degeneration...