Simona Gurzu

Summary

Publications

  1. ncbi request reprint The correlation between the immunostains for p53 and Ki67 with bcl-2 expression and classical prognostic factors in colorectal carcinomas
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, 38 Gheorghe Marinescu Street, Targu Mures, Romania
    Rom J Morphol Embryol 48:95-9. 2007
  2. ncbi request reprint The immunohistochemical aspects of protein Mena in cervical lesions
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 50:213-6. 2009
  3. doi request reprint Hereditary diffuse gastric cancer--An overview
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania Electronic address
    Pathol Res Pract 211:629-32. 2015
  4. ncbi request reprint Giant gastrointestinal stromal tumor of the stomach: a challenging diagnostic and therapeutically approach
    Tivadar Bara
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:1503-6. 2015
  5. ncbi request reprint Geographic particularities in incidence and etiopathogenesis of sporadic gastric cancer
    Zoltán Kádár
    Gurzu Simona, University of Medicine and Pharmacy, Tirgu Mures, Ghe Marinescu 38 street, 540139 Tirgu Mures, Romania, E mail
    Pol J Pathol 66:254-9. 2015
  6. ncbi request reprint Correlation of angiogenesis with other immunohistochemical markers in cutaneous basal and squamous cell carcinomas
    Carmen Diana Ciortea
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:665-70. 2015
  7. ncbi request reprint Arteriovenous synovial hemangioma of the popliteal fossa diagnosed in an adolescent with history of unilateral congenital clubfoot: case report and a single-institution retrospective review
    Zoltan Derzsi
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:549-52. 2015
  8. doi request reprint The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, 38 Ghe Marinescu Street, 540139, Tirgu Mures, Romania
    Arch Dermatol Res 307:151-7. 2015
  9. pmc The possible role of Mena protein and its splicing-derived variants in embryogenesis, carcinogenesis, and tumor invasion: a systematic review of the literature
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, 38 Ghe Marinescu Street, 540193 Targu Mures, Romania
    Biomed Res Int 2013:365192. 2013
  10. pmc Lethal cardiotoxicity, steatohepatitis, chronic pancreatitis, and acute enteritis induced by capecitabine and oxaliplatin in a 36-year-old woman
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania
    Diagn Pathol 8:150. 2013

Collaborators

  • T Mezei
  • Zoltan Szentirmay
  • Erika Toth
  • J Jung
  • Anca M Cimpean
  • Judit Kovacs
  • M Raica
  • Istvan Ember
  • Emoke Horváth
  • Zsolt Orosz
  • M Turcu
  • Z Pávai
  • Ioan Jung
  • Tivadar Bara
  • Zoltan Derzsi
  • I Jung
  • Zoltán Kádár
  • Attila Kovecsi
  • Ioana Hălmaciu
  • Sabin Gligore Turdean
  • Örs Nagy
  • Tudor Sorin Pop
  • Horea Gozar
  • Mircea Golea
  • Haruhiko Sugimura
  • Bogdan Andrei Suciu
  • AncuŢa Marilena Zazgyva
  • Carmen Diana Ciortea
  • Sabin Turdean
  • S Turdean
  • R Melinte
  • Raluca Amalia Ceauşu
  • I Egyed-Zsigmond
  • Mircea Muresan
  • Janos Szederjesi
  • Anca Moţăţăianu
  • Leonard Azamfirei
  • Iunius Simu
  • Lucian Marginean
  • Zsolt Kovacs
  • Rodica Balasa
  • Doina Milutin
  • Septimiu Popescu
  • Klara Branzaniuc
  • Danut Ioan Sahlean
  • Diana Ciortea
  • Ileana László
  • Gurzu Simona
  • Gheorghe Műhlfay
  • Daniela Sala
  • Calin Molnar
  • Radu Mircea Neagoe
  • Anca Otilia Contac
  • Janina Orlowska
  • Ionela Paşcanu
  • Mircea Ardelean
  • S Voidazan
  • Minodora Dobreanu
  • B A Suciu
  • Lia Georgescu
  • Klara Brînzaniuc
  • Anca Sin
  • Pusa Gaje
  • Gabriella Marton
  • Ileana Egyed-Zsigmond

Detail Information

Publications51

  1. ncbi request reprint The correlation between the immunostains for p53 and Ki67 with bcl-2 expression and classical prognostic factors in colorectal carcinomas
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, 38 Gheorghe Marinescu Street, Targu Mures, Romania
    Rom J Morphol Embryol 48:95-9. 2007
    ..For statistical analysis, we used the Statistical Program Graph Pad In Stat 3-Trial Version. We considered the significant association when p<0.05, with 95% confidence interval...
  2. ncbi request reprint The immunohistochemical aspects of protein Mena in cervical lesions
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 50:213-6. 2009
    ..We analyzed 30 cases with CIN (1, 2 and 3), and 10 squamous carcinomas. We used the EnVision system by LabVision. The Mena antibody, izotype mouse IgA, clone 21, provided by BD Biosciences...
  3. doi request reprint Hereditary diffuse gastric cancer--An overview
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania Electronic address
    Pathol Res Pract 211:629-32. 2015
    ..We also provide a comprehensive, up-to-date review of genetic counseling and criteria for screening and surveillance of eligible families. ..
  4. ncbi request reprint Giant gastrointestinal stromal tumor of the stomach: a challenging diagnostic and therapeutically approach
    Tivadar Bara
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:1503-6. 2015
    ..This case highlights that a well-conducted trans-disciplinary approach can have real benefits, even in borderline-operable giant potentially-malignant GISTs. New criteria to establish the malignant potential of GIST should be explored. ..
  5. ncbi request reprint Geographic particularities in incidence and etiopathogenesis of sporadic gastric cancer
    Zoltán Kádár
    Gurzu Simona, University of Medicine and Pharmacy, Tirgu Mures, Ghe Marinescu 38 street, 540139 Tirgu Mures, Romania, E mail
    Pol J Pathol 66:254-9. 2015
    ..Geographic prevalence of specific Helicobacter pylori strains is also synthesized. The pathogenesis of gastric cancer in patients from countries of the authors, respectively Japan, Romania, Hungary and Poland, is particularly examined. ..
  6. ncbi request reprint Correlation of angiogenesis with other immunohistochemical markers in cutaneous basal and squamous cell carcinomas
    Carmen Diana Ciortea
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:665-70. 2015
    ..The angiogenesis was quantified in 38 randomly selected cases of SCCs and 17 BCCc, respectively, using the antibodies vascular endothelial growth factor (VEGF-A) and COX-2, while the microvessel density (MVD) was evaluated with the CD31...
  7. ncbi request reprint Arteriovenous synovial hemangioma of the popliteal fossa diagnosed in an adolescent with history of unilateral congenital clubfoot: case report and a single-institution retrospective review
    Zoltan Derzsi
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:549-52. 2015
    ..SH of the knee should be excised as soon as possible to avoid complications such as muscle invasion and risk of recurrence. ..
  8. doi request reprint The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, 38 Ghe Marinescu Street, 540139, Tirgu Mures, Romania
    Arch Dermatol Res 307:151-7. 2015
    ..The immunoprofile suggests that the GCT seems to have an endomesenchymal origin. The c-KIT and RET positivity, associated with microsatellite stability, and the immunoprofile of the ovoid bodies have never reported before in GCTs...
  9. pmc The possible role of Mena protein and its splicing-derived variants in embryogenesis, carcinogenesis, and tumor invasion: a systematic review of the literature
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, 38 Ghe Marinescu Street, 540193 Targu Mures, Romania
    Biomed Res Int 2013:365192. 2013
    ....
  10. pmc Lethal cardiotoxicity, steatohepatitis, chronic pancreatitis, and acute enteritis induced by capecitabine and oxaliplatin in a 36-year-old woman
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania
    Diagn Pathol 8:150. 2013
    ..Alcohol consumption was denied. The patient died due to associated heart, liver and pancreatic failure. This multiorgan toxicity and death following CAPOX regimen had not yet been reported in the literature...
  11. pmc Mesenchymal-to-endothelial transition in Kaposi sarcoma: a histogenetic hypothesis based on a case series and literature review
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania
    PLoS ONE 8:e71530. 2013
    ..The aim of our study was to analyze the immunophenotype of Kaposi sarcoma and to present a hypothesis about the histogenesis of this tumor, based on a case series and a review of relevant literature...
  12. doi request reprint Practical value of the new system for Maspin assessment, in colorectal cancer
    S Gurzu
    Department of Pathology, University of Medicine and Pharmacy, Targu Mures, Romania
    Neoplasma 60:373-83. 2013
    ..In conclusion, CRC with cytoplasmic predominance and mixed Maspin expression seems to present better prognosis whereas nuclear predominance is connected with high aggressivity...
  13. ncbi request reprint Molecular classification of colorectal cancer: a dream that can become a reality
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 54:241-5. 2013
    ..At the end, we correlated these informations and tried to realize a molecular classification of colorectal cancer, similar to breast carcinomas, in order to establish targeted groups of patients for targeted therapy...
  14. pmc Serrated pathway adenocarcinomas: molecular and immunohistochemical insights into their recognition
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Targu Mures, Romania
    PLoS ONE 8:e57699. 2013
    ..The aim of our paper was to establish some criteria to facilitate their identification...
  15. doi request reprint Gastric tricho-wool bezoar in an 18-year-old girl
    S Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    S Afr J Surg 51:33-4. 2013
    ..On palpation, a painful abdominal mass was identified in the epigastric region, and gastrotomy was performed. A J-shaped hair-wool ball and two large pieces of sheep's wool were removed. No history of trichotillomania was reported...
  16. ncbi request reprint Possible predictive value of maspin expression in colorectal cancer
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy, 38 Ghe Marinescu Street, Targu Mures, 540139, Romania
    Recent Pat Anticancer Drug Discov 8:183-90. 2013
    ....
  17. doi request reprint Non-Epstein-Barr virus associated lymphoepithelioma-like carcinoma of the esophagogastric junction with microsatellite instability, K-ras wild type
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy, Targu Mures, Romania
    Pathol Res Pract 209:128-31. 2013
    ..Real-time PCR analysis showed microsatellite instability without K-ras mutation in codon 12. No recurrences or metastases were reported 6 months after surgical intervention. No adjuvant therapy was performed...
  18. doi request reprint Male breast cellular myofibroblastoma with a rich reticulinic network: case report
    Simona Gurzu
    University of Medicine and Pharmacy, Targu Mures, Romania
    Am J Mens Health 6:344-8. 2012
    ..More than 90% of the cells expressed estrogen receptor. No recurrences were reported 2 years after surgical excision. This case is a variant of cellular myofibroblastoma, with a rich reticulinic network and scanty collagen bands...
  19. ncbi request reprint VEGF and CD31 expression in arthritic synovium and cartilage of human knee joints
    R Melinte
    Department of Orthopedic Surgery, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 53:911-5. 2012
    ..To determine the histological differences and the particular aspects of local angiogenesis in knee joint of the patients with osteoarthritis (OA) and rheumatoid arthritis (RA)...
  20. ncbi request reprint Current data in clinicopathological characteristics of primary hepatic tumors
    S Turdean
    Dr Gheorghe Marinescu Municipal Hospital, and University of Medicine and Pharmacy of Târgu Mureş, Romania
    Rom J Morphol Embryol 53:719-24. 2012
    ..The present study aimed to investigate the status of primary liver tumors diagnosed in the Emergency Hospital of Mures County, Romania...
  21. doi request reprint Aberrant pattern of the cytokeratin 7/cytokeratin 20 immunophenotype in colorectal adenocarcinomas with BRAF mutations
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Pathol Res Pract 208:163-6. 2012
    ..This is the first reported study of the relationship between CK20/CK7 immunophenotype, BRAF mutations and microsatellite status in CRC...
  22. pmc Mena, a new available marker in tumors of salivary glands?
    S Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Eur J Histochem 56:e8. 2012
    ..Its positivity in endothelial cells may suggest its potential role in tumor angiogenesis...
  23. ncbi request reprint Synchronous intestinal tumors: aggressive jejunal carcinoid and sigmoid malignant polyp
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 53:193-6. 2012
    ..In this case, the prognosis was not depending by the colorectal tumors but the aggressive feature of jejunal carcinoid lead to patient's death...
  24. ncbi request reprint Practical value of the complex analysis of sentinel lymph nodes in colorectal carcinomas
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 52:593-8. 2011
    ..Sentinel lymph nodes (SLNs) mapping is a very controversial method, which can increase the number of identified LN...
  25. ncbi request reprint The aspects of angiogenesis in anal canal carcinomas compared with that in colorectal carcinomas
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy, Targu Mures, Romania
    Rom J Morphol Embryol 48:349-53. 2007
    ..To compare the angiogenesis in anal canal carcinomas (ACC) with that in colorectal carcinomas (CRC)...
  26. ncbi request reprint The expression of cytoskeleton regulatory protein Mena in colorectal lesions
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy, Targu Mures, Romania
    Rom J Morphol Embryol 49:345-9. 2008
    ..This is the first study in the literature about Mena expression in colorectal lesions...
  27. ncbi request reprint The angiogenesis in colorectal carcinomas with and without lymph node metastases
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy, Targu Mures, Romania
    Rom J Morphol Embryol 49:149-52. 2008
    ..We studied 187 CRC, with and without lymph node metastases, 128 from left and 59 from right colon...
  28. ncbi request reprint The differences between the endothelial area marked with CD31 and CD105 in colorectal carcinomas by computer-assisted morphometrical analysis
    I Jung
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 50:239-43. 2009
    ..Two hundred and eleven surgical specimens with CRC were immunohistochemical analyzed with markers for angiogenesis CD31 and CD105 (Endoglin). We determined the area of endothelial cells occupied in the microscope field (EA)...
  29. doi request reprint Counting of angiogenesis in colorectal carcinomas using double immunostain
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Tumori 98:485-90. 2012
    ..Double-labeling immunostaining is indispensable to study vessel maturation grade...
  30. ncbi request reprint Relationship of endothelial area with VEGF-A, COX-2, maspin, c-KIT, and DOG-1 immunoreactivity in liposarcomas versus non-lipomatous soft tissue tumors
    Ioan Jung
    Department of Pathology, University of Medicine and Pharmacy Tirgu Mures, Romania
    Int J Clin Exp Pathol 8:1776-82. 2015
    ..The DOG-1/c-KIT/VEGF target may be used for further personalized therapy of soft tissue sarcomas. No data about DOG-1 and maspin positivity in liposarcomas have been published to date. ..
  31. ncbi request reprint [Preliminary results regarding vascular endothelial growth factor (VEGF-A) levels in the serum of gastric cancer patients]
    Ioana Hălmaciu
    Departamentul de Anatomic şi Embriologie, Universitatea de Medicina si Farmacie, Targu Mures, Romania
    Rev Med Chir Soc Med Nat Iasi 116:446-51. 2012
    ..The most studied VEGF molecule is VEGF-A (Vascular Endothelial Growth Factor). Its involvement in various neoplastic processes represents an intensely controversial hypothesis...
  32. doi request reprint Gastric cancer in young vs old Romanian patients: immunoprofile with emphasis on maspin and mena protein reactivity
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy, Tirgu Mures, Romania
    APMIS 123:223-33. 2015
    ....
  33. pmc Mixed adenoneuroendocrine carcinoma of gastrointestinal tract: report of two cases
    Simona Gurzu
    Simona Gurzu, Zoltan Kadar, Adrian Tamasi, Ioan Jung, Department of Pathology, University of Medicine and Pharmacy, 540139 Tirgu Mures, Romania
    World J Gastroenterol 21:1329-33. 2015
    ..The aggressiveness seems to depend on the endocrine component, independent of its proportion. The neuroendocrine component could be a dedifferentiated adenocarcinoma with a neuroendocrine phenotype. ..
  34. doi request reprint Clinical significance of carcinoembryonic antigen expression of acellular mucin pools after preoperative chemoradiotherapy of rectal carcinoma
    Simona Gurzu
    1 Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania
    Cancer Biother Radiopharm 29:295-7. 2014
    ..The aims of this study were to analyze the immunoprofile of acellular mucin pools and to review the relevant literature...
  35. ncbi request reprint Microvascular density in non-Hodgkin B-cell lymphomas measured using digital morphometry
    T Mezei
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 53:67-71. 2012
    ..The microvascular component of a tumor also plays a role in the metastatic capacity of the tumor, enabling the tumor cells to spread to distant locations by providing a large endothelial surface...
  36. doi request reprint First Case Report of a Sporadic Adrenocortical Carcinoma With Gastric Metastasis and a Synchronous Gastrointestinal Stromal Tumor of the Stomach
    Attila Kovecsi
    From the Department of Pathology AK, IJ, ZK, SG Department of Surgery TB, TjB and Intensive Care Unit, University of Medicine and Pharmacy of Tirgu Mures, Targu Mures, Romania LA
    Medicine (Baltimore) 94:e1549. 2015
    ..So far, as we know, this is the 15th case of ever reported synchronous/metachronous sporadic ACCs; the ACC-related gastric metastases either synchronous ACC and GIST, has not been reported in the literature previously...
  37. doi request reprint Single skip metastasis in sentinel lymph node: In an early gastric cancer
    Tivadar Bara
    Tivadar Jr Bara, Tivadar Bara, Department of Surgery, University of Medicine and Pharmacy, 540139 Tirgu Mures, Romania
    World J Gastroenterol 21:9803-7. 2015
    ..In this representative case, low-cost SLN mapping, with a longer intraoperative waiting time, totally changed the stage of the tumor in a patient with EGC. ..
  38. pmc Kite versus Ponseti Method in the Treatment of 235 Feet With Idiopathic Clubfoot: Results of a Single Romanian Medical Center
    Zoltan Derzsi
    From the Department of Pediatric Surgery ZD, HG Department of Orthopedic Surgery ÖN, TSP and Department of Pathology, University of Medicine and Pharmacy, Tirgu Mures, Romania SG
    Medicine (Baltimore) 94:e1379. 2015
    ..Dimeglio score can be successfully used for evaluation of these children. This is the eighth published study that compare the efficacy of Kite versus Ponseti method...
  39. ncbi request reprint CD105/Ki67 double immunostaining expression in liver metastasis from colon carcinoma
    Raluca Amalia Ceauşu
    Department of Histology, Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
    Rom J Morphol Embryol 52:613-6. 2011
    ..We conclude that in liver metastasis principal mechanism of neovascularisation formation is based on intussusception...
  40. doi request reprint Significant Shrinkage of Multifocal Liver Metastases and Long-Term Survival in a Patient With Rectal Cancer, After Trans-Arterial Chemoembolization (TACE): A Case Report
    Bogdan Andrei Suciu
    From the Department of Surgery, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania BAS, CM Department of Anatomy and Embryology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania BAS, IH, KB Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania SG, DM, IJ and Department of Radiology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania LM, IH
    Medicine (Baltimore) 94:e1848. 2015
    ..This representative case shows that an efficient trans-disciplinary approach could lead to successful therapeutic management even in patients with advanced-staged colorectal carcinomas...
  41. ncbi request reprint S53P4 bioactive glass and fibrin glue for the treatment of osteochondral lesions of the knee - a preliminary in vivo study in rabbits
    AncuŢa Marilena Zazgyva
    Department of Otolaryngology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 56:1085-90. 2015
    ....
  42. ncbi request reprint Giant Cavernous Hepatic Hemangioma Diagnosed Incidentally in a Perimenopausal Obese Female with Endometrial Adenocarcinoma: A Case Report
    Tivadar Bara
    Department of Surgery, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania
    Anticancer Res 36:769-72. 2016
    ..Because obesity may cause hyperestrogenism, it might both increase the growth rate of hemangioma and the genesis of endometrial cancer in perimenopausal females. ..
  43. pmc A coin-like peripheral small cell lung carcinoma associated with acute paraneoplastic axonal Guillain-Barre-like syndrome
    Ioan Jung
    From the Department of Pathology IJ, SG, AOC, SP Department of Neurology RB, AM and Department of Radiology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania IH, IS
    Medicine (Baltimore) 94:e910. 2015
    ..This is the 6th reported case of small cell lung cancer-associated acute Guillain-Barre-like syndrome and the first report about an association with a coin-like peripheral pattern. ..
  44. doi request reprint Metaplastic bone formation in the abdominal wall--an incidental finding in a patient with gastric cancer. Case report and hypothesis about its histogenesis
    Simona Gurzu
    Departments of Pathology Surgery, University of Medicine and Pharmacy of Targu Mures, Romania
    Am J Dermatopathol 35:844-6. 2013
    ..The final diagnosis was localized metaplastic bone formation. This is a rare condition which can be related to trauma or surgery and should be differentiated by foreign-body granuloma and osteosarcoma...
  45. doi request reprint Unexpected maspin immunoreactivity in Merkel cell carcinoma
    Sabin Gligore Turdean
    Department of Pathology, University of Medicine and Pharmacy, 38 Ghe Marinescu Street, 540139, Tirgu Mures, Romania
    Diagn Pathol 10:206. 2015
    ..Maspin immunoreactivity was seen in cases 1 and 3. Not one of the cases expressed DOG-1 or even TTF-1. Furthermore, this is the first report in literature about maspin positivity in MCC that might be related to sun exposure...
  46. doi request reprint Aberrant metastatic behavior and particular features of early gastric cancer
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania
    APMIS 123:999-1006. 2015
    ....
  47. pmc Atypical Hepatocellular Neoplasm With Peliosis in Cirrhotic Liver Versus Hepatocellular Carcinoma: A Diagnostic Trap
    Simona Gurzu
    From Department of Pathology, University of Medicine and Pharmacy, Tirgu Mures, Romania SG, IJ, AOC, MT and Department of Surgery, University of Medicine and Pharmacy, Tirgu Mures, Romania AT
    Medicine (Baltimore) 94:e1189. 2015
    ..This histological entity is not yet included in the WHO Classification list...
  48. ncbi request reprint Immunohistochemical and molecular features of primary clear cell-adenocarcinoma of the rectum, as predictive factors for individualized therapy
    Simona Gurzu
    Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania
    Rom J Morphol Embryol 55:629-33. 2014
    ..Bevacizumab-based antiangiogenic therapy was indicated. This is the 12th primary CCA of the colorectum ever reported, and the first from Eastern Europe...
  49. ncbi request reprint Clinico-pathological particularities of the shock-related pancreatitis
    Judit Kovacs
    Department of Anesthesia and Intensive Care, University of Medicine and Pharmacy Tg Mures, Targu Mures, Romania
    Pathol Oncol Res 18:977-81. 2012
    ..We therefore recommend in patients with shock to consider the possible development of ischemic pancreatitis for prompt and efficient treatment...
  50. ncbi request reprint Immunohistochemical comparative study of fibrosis and biliary ductular reaction in alcoholic and viral chronic hepatitis
    I Egyed-Zsigmond
    Department of Pathology, University of Medicine and Pharmacy of Targu Mures, Romania
    Rom J Morphol Embryol 51:265-9. 2010
    ..We have concluded that patients with C viral hepatitis can benefit most from a correctly indicated hepatic biopsy since in these cases the lesions might be observed in an early and potentially curable phase...
  51. doi request reprint Surgical reconstruction of the genitalia in a 3-year-old infant with a 46XX karyotype: case report
    Horea Gozar
    Department of Pediatric Surgery, University of Medicine and Pharmacy, Tirgu Mures, Romania
    Aesthetic Plast Surg 38:549-53. 2014
    ..She had an uneventful postoperative period and the wound healed well with good cosmetic results. We present the details about the surgical procedure and a short review of data from literature...