Kurinchi Gurusamy

Summary

Publications

  1. doi request reprint Surgical treatment of gallstones
    Kurinchi S Gurusamy
    Department of Surgery, University College London Medical School, Royal Free Hospital, London, UK
    Gastroenterol Clin North Am 39:229-44, viii. 2010
  2. pmc Is sustained virological response a marker of treatment efficacy in patients with chronic hepatitis C viral infection with no response or relapse to previous antiviral intervention?
    Kurinchi S Gurusamy
    Department of Surgery, University College London, London, United Kingdom
    PLoS ONE 8:e83313. 2013
  3. doi request reprint Peritoneal closure versus no peritoneal closure for patients undergoing non-obstetric abdominal operations
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 7:CD010424. 2013
  4. doi request reprint Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD007196. 2013
  5. doi request reprint Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCLMedical School, London, UK
    Cochrane Database Syst Rev 6:CD005440. 2013
  6. doi request reprint T-tube drainage versus primary closure after laparoscopic common bile duct exploration
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD005641. 2013
  7. doi request reprint T-tube drainage versus primary closure after open common bile duct exploration
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD005640. 2013
  8. doi request reprint Somatostatin analogues for pancreatic surgery
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 4:CD008370. 2013
  9. doi request reprint Prophylactic gastrojejunostomy for unresectable periampullary carcinoma
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCLMedical School, London, UK
    Cochrane Database Syst Rev 2:CD008533. 2013
  10. doi request reprint Robot assistant versus human or another robot assistant in patients undergoing laparoscopic cholecystectomy
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 9:CD006578. 2012

Detail Information

Publications32

  1. doi request reprint Surgical treatment of gallstones
    Kurinchi S Gurusamy
    Department of Surgery, University College London Medical School, Royal Free Hospital, London, UK
    Gastroenterol Clin North Am 39:229-44, viii. 2010
    ....
  2. pmc Is sustained virological response a marker of treatment efficacy in patients with chronic hepatitis C viral infection with no response or relapse to previous antiviral intervention?
    Kurinchi S Gurusamy
    Department of Surgery, University College London, London, United Kingdom
    PLoS ONE 8:e83313. 2013
    ..There is sparse information on long-term mortality from RCTs...
  3. doi request reprint Peritoneal closure versus no peritoneal closure for patients undergoing non-obstetric abdominal operations
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 7:CD010424. 2013
    ..If closing the peritoneum could be omitted without complications, or even with benefit for patients, this could result in reductions in the cost of abdominal operations by reducing both the number of sutures used and the operating time...
  4. doi request reprint Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD007196. 2013
    ..Laparoscopic cholecystectomy involves several months of waiting if performed electively. However, people can develop life-threatening complications during this waiting period...
  5. doi request reprint Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCLMedical School, London, UK
    Cochrane Database Syst Rev 6:CD005440. 2013
    ..However, delaying surgery exposes the people to gallstone-related complications...
  6. doi request reprint T-tube drainage versus primary closure after laparoscopic common bile duct exploration
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD005641. 2013
    ..Use of T-tube drainage after laparoscopic common bile duct (CBD) exploration is controversial...
  7. doi request reprint T-tube drainage versus primary closure after open common bile duct exploration
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD005640. 2013
    ..Between 5% and 11% of people undergoing cholecystectomy have common bile duct stones. Stones may be removed at the time of cholecystectomy by opening and clearing the common bile duct. The optimal technique is unclear...
  8. doi request reprint Somatostatin analogues for pancreatic surgery
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 4:CD008370. 2013
    ..Synthetic analogues of somatostatin are advocated by some surgeons to reduce complications following pancreatic surgery; however, their use is controversial...
  9. doi request reprint Prophylactic gastrojejunostomy for unresectable periampullary carcinoma
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCLMedical School, London, UK
    Cochrane Database Syst Rev 2:CD008533. 2013
    ..The role of prophylactic gastrojejunostomy in patients with unresectable periampullary cancer is controversial...
  10. doi request reprint Robot assistant versus human or another robot assistant in patients undergoing laparoscopic cholecystectomy
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 9:CD006578. 2012
    ..While some trials have shown distinct advantages of a robotic assistant over a human assistant others have not, and it is unclear which robotic assistant is best...
  11. doi request reprint Somatostatin analogues for pancreatic surgery
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 6:CD008370. 2012
    ..Synthetic analogues of somatostatin are advocated by some surgeons to reduce complications following pancreatic surgery, however their use is controversial...
  12. doi request reprint Cardiopulmonary interventions to decrease blood loss and blood transfusion requirements for liver resection
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 5:CD007338. 2012
    ..Blood loss during liver resection is considered one of the most important factors affecting the peri-operative outcomes of patients undergoing liver resection...
  13. doi request reprint Abdominal lift for laparoscopic cholecystectomy
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 5:CD006574. 2012
    ..These cardiopulmonary changes may not be tolerated in individuals with poor cardiopulmonary reserve...
  14. doi request reprint Techniques of flushing and reperfusion for liver transplantation
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 3:CD007512. 2012
    ..Various techniques of flushing and reperfusion have been advocated to improve outcomes after liver transplantation. There is considerable uncertainty as to which method is superior...
  15. doi request reprint Wound drains after incisional hernia repair
    Kurinchi Selvan Gurusamy
    Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Cochrane Database Syst Rev 2:CD005570. 2012
    ..More than 50% of open mesh repairs of ventral hernias have drains inserted. However, there is uncertainty as to whether drains are associated with benefits or harm to the patient...
  16. doi request reprint Intra-operative vs pre-operative endoscopic sphincterotomy in patients with gallbladder and common bile duct stones: cost-utility and value-of-information analysis
    Kurinchi Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free Campus UCL Medical School, London, UK
    Appl Health Econ Health Policy 10:15-29. 2012
    ..Recently, a meta-analysis has shown that intra-operative ES during laparoscopic cholecystectomy (IOES) results in fewer complications than POES, with similar efficacy. The cost effectiveness of IOES versus POES is unknown...
  17. doi request reprint Systematic review and meta-analysis of intraoperative versus preoperative endoscopic sphincterotomy in patients with gallbladder and suspected common bile duct stones
    K Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free Campus, University College London Medical School, London, UK
    Br J Surg 98:908-16. 2011
    ..Recently, intraoperative endoscopic sphincterotomy (IOES) during laparoscopic cholecystectomy has been suggested as an alternative treatment...
  18. pmc Current protective strategies in liver surgery
    Kurinchi S Gurusamy
    HPB and Liver Transplantation, Royal Free Campus, University College London Medical School, Royal Free Hospital, 9th Floor, Pond Street, London, NW3 2QG, United Kingdom
    World J Gastroenterol 16:6098-103. 2010
    ..Further well designed randomized controlled trials are necessary to assess the various new protective strategies in liver resection...
  19. ncbi request reprint Trace element concentration in primary liver cancers--a systematic review
    Kurinchi Gurusamy
    HBP and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, London, UK
    Biol Trace Elem Res 118:191-206. 2007
    ..Development of hepatocellular carcinoma has been linked to levels of trace elements. This review summarizes the evidence associating HCC with trace elements...
  20. ncbi request reprint An evaluation study of trace element content in colorectal liver metastases and surrounding normal livers by X-ray fluorescence
    Kurinchi S Gurusamy
    HPB and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, UCL and Royal Free Hospital NHS Trust, Pond Street, London, NW3 2QG, UK
    Biometals 21:373-8. 2008
    ..Trace elements are involved in many key pathways involving cell cycle control. The levels of trace metals such as iron, copper, and zinc in colorectal liver metastases have not previously been assessed...
  21. doi request reprint Meta-analysis of randomized controlled trials on the safety and effectiveness of day-case laparoscopic cholecystectomy
    K Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, University College London and Royal Free Hospital NHS Trust, London, UK
    Br J Surg 95:161-8. 2008
    ..The aim of this meta-analysis is to assess the advantages and disadvantages of day-case surgery compared with overnight stay in patients undergoing elective laparoscopic cholecystectomy...
  22. doi request reprint Systematic review of randomized controlled trials on the effectiveness of virtual reality training for laparoscopic surgery
    K Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, University College London and Royal Free Hospital NHS Trust, London NW32QG, UK
    Br J Surg 95:1088-97. 2008
    ..The aim of this review was to determine whether virtual reality (VR) training can supplement and/or replace conventional laparoscopic training in surgical trainees with limited or no laparoscopic experience...
  23. doi request reprint Assessment of risk of bias in randomized clinical trials in surgery
    K S Gurusamy
    University Department of Surgery, Royal Free Hospital and University College School of Medicine, London, UK
    Br J Surg 96:342-9. 2009
    ..Bias in RCTs may overestimate or underestimate the true effectiveness of an intervention...
  24. doi request reprint Meta-analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis
    K Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, London, UK
    Br J Surg 97:141-50. 2010
    ....
  25. doi request reprint Design of surgical randomized controlled trials involving multiple interventions
    Kurinchi S Gurusamy
    University Department of Surgery, Royal Free Campus, UCL Medical School, London, United Kingdom
    J Surg Res 165:118-27. 2011
    ..Surgical trials evaluating multiple interventions can be carried out by using parallel or factorial trial design. The optimal trial method has not been established...
  26. doi request reprint Influence of zinc and zinc chelator on HT-29 colorectal cell line
    K S Gurusamy
    University Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Biometals 24:143-51. 2011
    ..HT-29 cells are not able to counteract the effect of intracellular chelation of zinc by altering zinc transport. Further research into the mechanisms of these findings is necessary and may lead to novel therapeutic options...
  27. ncbi request reprint Trace element concentration in metastatic liver disease: a systematic review
    K Gurusamy
    Department of HPB and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, UCL and Royal Free Hospital NHS Trust, London, UK
    J Trace Elem Med Biol 21:169-77. 2007
    ..There are conflicting reports about the levels of trace elements in secondary liver cancers. This review summarises the evidence associating secondary liver tumours with trace elements...
  28. pmc Systematic review of randomized controlled trials of pharmacological interventions to reduce ischaemia-reperfusion injury in elective liver resection with vascular occlusion
    Mahmoud Abu-Amara
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, Royal Free Hospital Campus, London, UK
    HPB (Oxford) 12:4-14. 2010
    ..We performed a systematic review and meta-analysis to assess the benefits and harms of using various pharmacological agents to decrease IR injury during liver resection with vascular occlusion...
  29. doi request reprint Clinical outcomes of radiofrequency ablation, percutaneous alcohol and acetic acid injection for hepatocelullar carcinoma: a meta-analysis
    Giacomo Germani
    The Royal Free Sheila Sherlock Liver Centre and University Department of Surgery, Royal Free Hospital, Pond Street, London, UK
    J Hepatol 52:380-8. 2010
    ..Robust evidence showing benefit of one therapy versus another is lacking. Our aim was to evaluate the evidence comparing RFA, PEI and PAI using meta-analytical techniques...
  30. doi request reprint Prevention of parastomal herniation with biologic/composite prosthetic mesh: a systematic review and meta-analysis of randomized controlled trials
    Sanjaya Prabhath Wijeyekoon
    Academic Surgical Unit, Barts and the London School of Medicine and Dentistry, Whitechapel, London, United Kingdom
    J Am Coll Surg 211:637-45. 2010
    ..A systematic review with meta-analysis of randomized clinical trials was performed to determine the benefits and risks of mesh reinforcement versus conventional stoma formation in preventing parastomal herniation...
  31. ncbi request reprint A meta-analysis of the impact of the two-layer method of preservation on human pancreatic islet transplantation
    Aditya Agrawal
    Department of HPB and Liver Transplant Surgery, Royal Free Hospital, Royal Free and University College School of Medicine, Hampstead, London NW3 2PF, UK
    Cell Transplant 17:1315-22. 2008
    ..There is currently no clear evidence that the TLM is beneficial in human islet transplantation. It may improve the preservation of marginal organs...