Manisha Gupta

Summary

Publications

  1. doi request reprint Activation and cell death in human dendritic cells infected with Nipah virus
    Manisha Gupta
    Viral Special Pathogens Branch, NCEZID, DHCPP, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 441:49-56. 2013
  2. ncbi request reprint CD8-mediated protection against Ebola virus infection is perforin dependent
    Manisha Gupta
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Immunol 174:4198-202. 2005
  3. doi request reprint Reduced virus replication, proinflammatory cytokine production, and delayed macrophage cell death in human PBMCs infected with the newly discovered Bundibugyo ebolavirus relative to Zaire ebolavirus
    Manisha Gupta
    Special Pathogens Branch, DVRD, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Virology 402:203-8. 2010
  4. ncbi request reprint Generation of eGFP expressing recombinant Zaire ebolavirus for analysis of early pathogenesis events and high-throughput antiviral drug screening
    Jonathan S Towner
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, NCID, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 332:20-7. 2005
  5. ncbi request reprint Ebola virus infection of human PBMCs causes massive death of macrophages, CD4 and CD8 T cell sub-populations in vitro
    Manisha Gupta
    Special Pathogens Branch, DVRD, Centers for Disease Control and Prevention, Mailstop G14, 1600 Clifton Road, Atlanta, GA 30333, USA
    Virology 364:45-54. 2007
  6. doi request reprint Serology and cytokine profiles in patients infected with the newly discovered Bundibugyo ebolavirus
    Manisha Gupta
    Viral Special Pathogens Branch, NCEZID, DHCPP, Centers for Disease Control and Prevention, Atlanta, GA 30033, USA
    Virology 423:119-24. 2012
  7. pmc Persistent infection with ebola virus under conditions of partial immunity
    Manisha Gupta
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 78:958-67. 2004

Detail Information

Publications7

  1. doi request reprint Activation and cell death in human dendritic cells infected with Nipah virus
    Manisha Gupta
    Viral Special Pathogens Branch, NCEZID, DHCPP, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 441:49-56. 2013
    ..Interestingly, DCs treated with inactivated NiV also show signs of apoptosis. These findings indicate that NiV infected DCs could play an important role in NiV pathogenesis...
  2. ncbi request reprint CD8-mediated protection against Ebola virus infection is perforin dependent
    Manisha Gupta
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Immunol 174:4198-202. 2005
    ..These findings suggest that the clearance of Ebola virus is perforin-dependent and provide an additional example showing that this basic immunologic mechanism is not limited to the clearance of noncytopathic viruses...
  3. doi request reprint Reduced virus replication, proinflammatory cytokine production, and delayed macrophage cell death in human PBMCs infected with the newly discovered Bundibugyo ebolavirus relative to Zaire ebolavirus
    Manisha Gupta
    Special Pathogens Branch, DVRD, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Virology 402:203-8. 2010
    ..The findings of slower Bundibugyo ebolavirus replication, lower production of proinflammatory cytokines and delay in macrophage cell death provide insight into the basis of the lower case fatality observed with Bundibugyo ebolavirus...
  4. ncbi request reprint Generation of eGFP expressing recombinant Zaire ebolavirus for analysis of early pathogenesis events and high-throughput antiviral drug screening
    Jonathan S Towner
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, NCID, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 332:20-7. 2005
    ..We show that Ebola-eGFP virus (EboZ-eGFP) infects known early targets of human infections and serves as an ideal model to screen antiviral compounds in less time than any previously published assay...
  5. ncbi request reprint Ebola virus infection of human PBMCs causes massive death of macrophages, CD4 and CD8 T cell sub-populations in vitro
    Manisha Gupta
    Special Pathogens Branch, DVRD, Centers for Disease Control and Prevention, Mailstop G14, 1600 Clifton Road, Atlanta, GA 30333, USA
    Virology 364:45-54. 2007
    ..These data suggest that Ebola virus evades the immune response by causing massive lymphocyte death. In addition, they may give an explanation on why the host is unable to produce a good antibody response in the absence of CD4 T cells...
  6. doi request reprint Serology and cytokine profiles in patients infected with the newly discovered Bundibugyo ebolavirus
    Manisha Gupta
    Viral Special Pathogens Branch, NCEZID, DHCPP, Centers for Disease Control and Prevention, Atlanta, GA 30033, USA
    Virology 423:119-24. 2012
    ..Thus, our results imply that disease severity in these patients is not due to the multi-organ failure and septic shock caused by a flood of inflammatory cytokines, as seen in infections with other Ebolavirus species...
  7. pmc Persistent infection with ebola virus under conditions of partial immunity
    Manisha Gupta
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 78:958-67. 2004
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