Ajay Kumar Gupta

Summary

Publications

  1. ncbi Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Biomaterials 26:1565-73. 2005
  2. ncbi Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications
    Ajay Kumar Gupta
    Laboratory for Nanoparticle Research, Formulation and Development Department, Torrent Research Centre, TPL, Village Bhat, Dist Gandhinagar 382 428, Gujarat, India
    Nanomedicine (Lond) 2:23-39. 2007
  3. ncbi Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for targeting cell surface receptors
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, United Kingdom
    Biomaterials 25:3029-40. 2004
  4. ncbi Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts
    Ajay Kumar Gupta
    Centre for Cell Engineering, IBLS, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 95:197-207. 2004
  5. ncbi Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    Ajay Kumar Gupta
    Crusade Laboratories Limited, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, Scotland, UK
    Biomaterials 26:3995-4021. 2005
  6. ncbi Surface modified superparamagnetic nanoparticles for drug delivery: interaction studies with human fibroblasts in culture
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Mater Sci Mater Med 15:493-6. 2004
  7. ncbi Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    IEEE Trans Nanobioscience 2:255-61. 2003
  8. ncbi Surface-modified superparamagnetic nanoparticles for drug delivery: preparation, characterization, and cytotoxicity studies
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    IEEE Trans Nanobioscience 3:66-73. 2004
  9. ncbi Hydrogel pullulan nanoparticles encapsulating pBUDLacZ plasmid as an efficient gene delivery carrier
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 99:157-66. 2004
  10. ncbi In vitro cytotoxicity studies of hydrogel pullulan nanoparticles prepared by AOT/N-hexane micellar system
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow, Scotland, United Kingdom
    J Pharm Pharm Sci 7:38-46. 2004

Collaborators

Detail Information

Publications11

  1. ncbi Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Biomaterials 26:1565-73. 2005
    ....
  2. ncbi Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications
    Ajay Kumar Gupta
    Laboratory for Nanoparticle Research, Formulation and Development Department, Torrent Research Centre, TPL, Village Bhat, Dist Gandhinagar 382 428, Gujarat, India
    Nanomedicine (Lond) 2:23-39. 2007
    ..We have reviewed the various biomedical applications with some of the most recent uses of magnetic nanoparticles for early detection of cancer, diabetes and atherosclerosis...
  3. ncbi Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for targeting cell surface receptors
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, United Kingdom
    Biomaterials 25:3029-40. 2004
    ..These experiments provide a route to prevent this problem, suggesting that cell response can be directed via specifically engineered particle surfaces...
  4. ncbi Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts
    Ajay Kumar Gupta
    Centre for Cell Engineering, IBLS, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 95:197-207. 2004
    ..These studies show that the gelatin nanoparticles prepared by water-in-oil microemulsion systems are endocytosed by the fibroblasts without being toxic to cells even at high concentration of nanoparticles...
  5. ncbi Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    Ajay Kumar Gupta
    Crusade Laboratories Limited, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, Scotland, UK
    Biomaterials 26:3995-4021. 2005
    ..This review discusses the synthetic chemistry, fluid stabilization and surface modification of superparamagnetic iron oxide nanoparticles, as well as their use for above biomedical applications...
  6. ncbi Surface modified superparamagnetic nanoparticles for drug delivery: interaction studies with human fibroblasts in culture
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Mater Sci Mater Med 15:493-6. 2004
    ..The modification of nanoparticle surface induced alterations in cell behaviour distinct from the unmodified particles, suggesting that cell response can be directed via specifically engineered particle surfaces...
  7. ncbi Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    IEEE Trans Nanobioscience 2:255-61. 2003
    ..The derivatized nanoparticles show high affinity for cell membrane and opens up new opportunities for magnetic cell separation and recovery that may be of crucial interest for the development of cellular therapies...
  8. ncbi Surface-modified superparamagnetic nanoparticles for drug delivery: preparation, characterization, and cytotoxicity studies
    Ajay Kumar Gupta
    Centre for Cell Engineering, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    IEEE Trans Nanobioscience 3:66-73. 2004
    ....
  9. ncbi Hydrogel pullulan nanoparticles encapsulating pBUDLacZ plasmid as an efficient gene delivery carrier
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    J Control Release 99:157-66. 2004
    ..The results of this study are encouraging for the development of pullulan nanoparticles as an intracellular delivery system for drugs and genes...
  10. ncbi In vitro cytotoxicity studies of hydrogel pullulan nanoparticles prepared by AOT/N-hexane micellar system
    Mona Gupta
    Division of Biochemistry and Molecular Biology, IBLS, Davidson Building, University of Glasgow, Glasgow, Scotland, United Kingdom
    J Pharm Pharm Sci 7:38-46. 2004
    ....
  11. ncbi Hypertriglyceridemia-induced acute pancreatitis--treatment with heparin and insulin
    Amitabh Monga
    Department of Internal Medicine, Sitaram Bhartia Institute of Science and Research, New Delhi 110 016
    Indian J Gastroenterol 22:102-3. 2003
    ..We report a 51-year-old man in whom treatment with heparin and insulin was accompanied by reduction in serum triglyceride levels and resolution of pancreatitis...