Identification of a novel antifungal peptide with chitin-binding property from marine metagenomeMuthuirulan Pushpanathan
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, India
Protein Pept Lett 19:1289-96. 2012
..The chitin binding property of the peptide was also confirmed by fast performance liquid chromatography...
Identification and characterization of alkaline serine protease from goat skin surface metagenomePaul Lavanya Pushpam
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India 625021
AMB Express 1:3. 2011
..The purified AS-protease with a molecular mass of ~63 kDa required a divalent cation (Co2+ or Mn2+) for its improved activity. The pH and temperature optima for this protease were 10.5 and 42°C respectively...
Global transcriptome analysis of Bacillus cereus ATCC 14579 in response to silver nitrate stressMalli Mohan Ganesh Babu
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Tamil Nadu, India
J Nanobiotechnology 9:49. 2011
..In addition, 14 distinct transcripts overexpressed from the 'empty' intergenic regions were also identified and proposed as stress-responsive non-coding small RNAs...
Genome sequence of Staphylococcus arlettae strain CVD059, isolated from the blood of a cardiovascular disease patientVasudevan Dinakaran
Department of Genetics, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamilnadu, India
J Bacteriol 194:6615-6. 2012
..Here, we report the genome sequence and potential virulence factors of this clinical isolate. The draft genome of S. arlettae CVD059 is 2,565,675 bp long with a G+C content of 33.5%...
Direct cell penetration of the antifungal peptide, MMGP1, in Candida albicansMuthuirulan Pushpanathan
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, India
J Pept Sci 18:657-60. 2012
..The MMGP1 treatment exhibited time-dependent cytotoxicity in C. albicans as evidenced by SYTOX Green (Molecular Probes Inc., Eugene, Oreg) uptake...
Inactivation of the transcriptional regulator-encoding gene sdiA enhances rice root colonization and biofilm formation in Enterobacter cloacae GS1Manoharan Shankar
Department of Genetics, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamilnadu, India
J Bacteriol 195:39-45. 2013
..Therefore, it is proposed that NAHLs produced by both plant and microbes in the rice rhizosphere act as cross-kingdom and interspecies signals to negatively impact cellular adhesion and, thereby, root colonization in E. cloacae GS1...
Influence of siderophore pyoverdine synthesis and iron-uptake on abiotic and biotic surface colonization of Pseudomonas putida S11Paramasivan Ponraj
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, 625021, Tamil Nadu, India
Biometals 25:1113-28. 2012
..The iron starvation tolerant mutant (IST3) exhibited enhanced pyoverdine-mediated iron uptake in minimal medium which significantly improved its biofilm formation, seed adhesion and competitive root colonization...
Genome sequence of the plant growth-promoting rhizobacterium Pseudomonas putida S11Paramasivan Ponraj
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamilnadu, India
J Bacteriol 194:6015. 2012
..The length of the draft genome sequence is approximately 5,970,799 bp, with a G+C content of 62.4%. The genome contains 6,076 protein-coding sequences...
Superantigen profiles of emm and emm-like typeable and nontypeable pharyngeal streptococcal isolates of South IndiaThangarajan Durai Anand
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, India
Ann Clin Microbiol Antimicrob 11:3. 2012
..In this study, the distribution of emm, emmL and superantigen genes was analyzed among the streptococcal strains isolated from the patients of acute pharyngitis...
Production, purification, and characterization of a β-glucosidase of Penicillium funiculosum NCL1Gurusamy Ramani
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, India
Appl Biochem Biotechnol 167:959-72. 2012
..The supplementation of Bgl3A (5 U/mg) with Trichoderma reesei cellulase complex (5 FPU/mg) resulted in about 70% of enhanced glucose production, which emphasizes the industrial importance of Bgl3A...
Genome sequence of the plant growth-promoting bacterium Enterobacter cloacae GS1Manoharan Shankar
Department of Genetics, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamilnadu, India
J Bacteriol 194:4479. 2012
..Analyses of the E. cloacae GS1 genome will throw light on the genetic factors involved in root colonization, growth promotion, and ecological success of this rhizobacterium...
Prevalence of bacteria in the circulation of cardiovascular disease patients, Madurai, IndiaVasudevan Dinakaran
Department of Genetics, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, India
Heart Lung Circ 21:281-3. 2012
..Coagulase negative Staphylococci (CoNS) was the most predominant group of bacteria and other notable bacterial species isolated in this study are discussed...
Functional characterization of a putative β-lactamase gene in the genome of Zymomonas mobilisK Narayanan Rajnish
Department of Genetics, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, India
Biotechnol Lett 33:2425-30. 2011
..Its optimal activity was at pH 6 and 30 °C. Further, the β-lactamase had a higher affinity towards penicillins than cephalosporin antibiotics...
Junker: an intergenic explorer for bacterial genomesJayavel Sridhar
Centre of Excellence in Bioinformatics, School of Biotechnology, Madurai Kamaraj University, Madurai 625021, Tamilnadu, India
Genomics Proteomics Bioinformatics 9:179-82. 2011
..The proposed web server is freely available at the URL http://pranag.physics.iisc.ernet.in/junker/...
Functional characterization of a new holin-like antibacterial protein coding gene tmp1 from goat skin surface metagenomeThangamani Rajesh
Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, India
Appl Microbiol Biotechnol 89:1061-73. 2011
..An improved activity of these mutant proteins is attributed to their increased hydrophobicity...