U Guller

Summary

Publications

  1. ncbi request reprint Surgical outcomes research based on administrative data: inferior or complementary to prospective randomized clinical trials?
    Ulrich Guller
    Department of Surgery, Division of General Surgery, University Hospital Basel, Basel, CH 4031, Switzerland
    World J Surg 30:255-66. 2006
  2. pmc Safety and effectiveness of bariatric surgery: Roux-en-Y gastric bypass is superior to gastric banding in the management of morbidly obese patients
    Ulrich Guller
    Center for Excellence in Bariatric Surgery, Humber River Regional Hospital Finch Site, University of Toronto, Department of Surgery, Toronto, ON, M3N 1N1, Canada
    Patient Saf Surg 3:10. 2009
  3. pmc Critical appraisal of meta-analyses: an introductory guide for the practicing surgeon
    Nathan Lawrentschuk
    European Board Certified Colo Proctology EBSQ, Department of Surgery, Division of Visceral Surgery and Transplantation, Inselspital, University of Bern, CH 3010 Bern, Switzerland
    Patient Saf Surg 3:16. 2009
  4. pmc Predicting gender differences as latent variables: summed scores, and individual item responses: a methods case study
    Ricardo Pietrobon
    Division of Orthopaedic Surgery, Center for Excellence in Surgical Outcomes, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Health Qual Life Outcomes 2:59. 2004
  5. pmc A suite of web applications to streamline the interdisciplinary collaboration in secondary data analyses
    Ricardo Pietrobon
    Center for Excellence in Surgical Outcomes, Duke University Medical Center, Duke University, Durham, NC, USA
    BMC Med Res Methodol 4:29. 2004
  6. doi request reprint Caveats in the interpretation of the surgical literature
    U Guller
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Br J Surg 95:541-6. 2008
  7. ncbi request reprint High hospital volume is associated with better outcomes for breast cancer surgery: analysis of 233,247 patients
    Ulrich Guller
    Department of Surgery, Division of General Surgery, University of Basel, Spitalstrasse 21, CH 4031, Basel, Switzerland
    World J Surg 29:994-9; discussion 999-1000. 2005
  8. pmc Detecting pheochromocytoma: defining the most sensitive test
    Ulrich Guller
    Department of Surgery, Divisions of General Surgery and Surgical Research, University Hospital Basel, Basel, Switzerland
    Ann Surg 243:102-7. 2006
  9. ncbi request reprint Trends in clinical trials in surgical oncology: implications for outcomes research
    Ulrich Guller
    American College of Surgeons Oncology Group and the Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Ther 25:684-98. 2003
  10. ncbi request reprint Sentinel lymph node biopsy is associated with improved survival compared to level I & II axillary lymph node dissection in node negative breast cancer patients
    I Langer
    Division General Surgery, University Hospital Basel, Basel, Switzerland
    Eur J Surg Oncol 35:805-13. 2009

Collaborators

Detail Information

Publications49

  1. ncbi request reprint Surgical outcomes research based on administrative data: inferior or complementary to prospective randomized clinical trials?
    Ulrich Guller
    Department of Surgery, Division of General Surgery, University Hospital Basel, Basel, CH 4031, Switzerland
    World J Surg 30:255-66. 2006
    ....
  2. pmc Safety and effectiveness of bariatric surgery: Roux-en-Y gastric bypass is superior to gastric banding in the management of morbidly obese patients
    Ulrich Guller
    Center for Excellence in Bariatric Surgery, Humber River Regional Hospital Finch Site, University of Toronto, Department of Surgery, Toronto, ON, M3N 1N1, Canada
    Patient Saf Surg 3:10. 2009
    ..The objective of this short overview is to provide a critical appraisal of the most relevant scientific evidence comparing laparoscopic gastric banding versus laparoscopic Roux-en-Y bypass in the treatment of morbidly obese patients...
  3. pmc Critical appraisal of meta-analyses: an introductory guide for the practicing surgeon
    Nathan Lawrentschuk
    European Board Certified Colo Proctology EBSQ, Department of Surgery, Division of Visceral Surgery and Transplantation, Inselspital, University of Bern, CH 3010 Bern, Switzerland
    Patient Saf Surg 3:16. 2009
    ....
  4. pmc Predicting gender differences as latent variables: summed scores, and individual item responses: a methods case study
    Ricardo Pietrobon
    Division of Orthopaedic Surgery, Center for Excellence in Surgical Outcomes, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Health Qual Life Outcomes 2:59. 2004
    ..This poses significant methodological challenges. The objective of this article is to present three different methods to predict latent variables based on classical summed scores, individual item responses, and latent variable models...
  5. pmc A suite of web applications to streamline the interdisciplinary collaboration in secondary data analyses
    Ricardo Pietrobon
    Center for Excellence in Surgical Outcomes, Duke University Medical Center, Duke University, Durham, NC, USA
    BMC Med Res Methodol 4:29. 2004
    ..We describe a system of web applications designed to streamline the interdisciplinary collaboration in outcomes research...
  6. doi request reprint Caveats in the interpretation of the surgical literature
    U Guller
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Br J Surg 95:541-6. 2008
    ..This is important if research findings are to be transferred appropriately into the realm of clinical practice...
  7. ncbi request reprint High hospital volume is associated with better outcomes for breast cancer surgery: analysis of 233,247 patients
    Ulrich Guller
    Department of Surgery, Division of General Surgery, University of Basel, Spitalstrasse 21, CH 4031, Basel, Switzerland
    World J Surg 29:994-9; discussion 999-1000. 2005
    ..The objective of this investigation was to assess the relationship between hospital volume and outcomes for breast cancer surgery...
  8. pmc Detecting pheochromocytoma: defining the most sensitive test
    Ulrich Guller
    Department of Surgery, Divisions of General Surgery and Surgical Research, University Hospital Basel, Basel, Switzerland
    Ann Surg 243:102-7. 2006
    ..To define the most sensitive biochemical test to establish the diagnosis of pheochromocytoma and also to assess the potential role of iodine 131-labeled metaiodobenzylguanidine scintigraphy (I-MIBG) in the diagnosis of this tumor...
  9. ncbi request reprint Trends in clinical trials in surgical oncology: implications for outcomes research
    Ulrich Guller
    American College of Surgeons Oncology Group and the Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Ther 25:684-98. 2003
    ..The goal of this article is to summarize and assess some of the trends in clinical trials in surgical oncology. Examples of ongoing studies or of trials in development from the American College of Surgeons Oncology Group are discussed...
  10. ncbi request reprint Sentinel lymph node biopsy is associated with improved survival compared to level I & II axillary lymph node dissection in node negative breast cancer patients
    I Langer
    Division General Surgery, University Hospital Basel, Basel, Switzerland
    Eur J Surg Oncol 35:805-13. 2009
    ....
  11. ncbi request reprint Discrete improvement in racial disparity in survival among patients with stage IV colorectal cancer: a 21-year population-based analysis
    A W Castleberry
    Department of Surgery, Duke University Medical Center, 27710, Durham, NC, USA
    J Gastrointest Surg 18:1194-204. 2014
    ..Recently, multiple clinical trials have demonstrated improved outcomes in patients with metastatic colorectal cancer. This study investigated if the improved survival is race dependent...
  12. doi request reprint Population-based trend analysis of 2813 patients undergoing laparoscopic sigmoid resection
    U Guller
    Department of Surgery, University of Toronto, Toronto, Canada
    Br J Surg 97:79-85. 2010
    ..The objective of this trend analysis was to assess whether clinical outcomes following laparoscopic sigmoid resection for diverticular disease have improved over the past 10 years...
  13. pmc Elevated preoperative CEA is associated with worse survival in stage I-III rectal cancer patients
    I Tarantino
    Department of Surgery, Kantonsspital St Gallen, 9007 St Gallen, Switzerland
    Br J Cancer 107:266-74. 2012
    ..The objective of this investigation was to assess whether preoperative carcinoembryonic antigen (CEA) level is an independent predictor of overall survival in rectal cancer patients...
  14. ncbi request reprint Propensity scores and the surgeon
    M Adamina
    Division of General Surgery and Institute for Surgical Research and Hospital Management, University of Basel, Hebelstrasse 20, CH 4031 Basel, Switzerland
    Br J Surg 93:389-94. 2006
    ..Unfortunately, many surgeons are unaware of this important analytical approach that has gained increasing stature in medical research. Thus, propensity score analyses are not used often in surgical studies...
  15. doi request reprint Population-based trend analysis of laparoscopic Nissen and Toupet fundoplications for gastroesophageal reflux disease
    U Zingg
    Department of Surgery, University Hospital Basel, 4031, Basel, Switzerland
    Surg Endosc 24:3080-5. 2010
    ..This study was designed to analyze trends in the use of Nissen versus Toupet fundoplications, and corresponding short-term outcomes during a 10-year period between 1995 and 2004...
  16. doi request reprint Negative appendicectomy and perforation rates in patients undergoing laparoscopic surgery for suspected appendicitis
    U Guller
    Department of Surgery, Division of Visceral Surgery and Transplantation, University of Berne, Berne, Switzerland
    Br J Surg 98:589-95. 2011
    ..This trend analysis examined whether rates of negative appendicectomy and perforated appendicitis have decreased over time, and sought to evaluate clinical predictors associated with negative appendicectomy and perforated appendicitis...
  17. ncbi request reprint Long-term outcomes of breast cancer patients after endoscopic axillary lymph node dissection: a prospective analysis of 52 patients
    I Langer
    Department of Surgery, University Hospital Basel, Spitalstrasse 21, CH 4031, Basel, Switzerland
    Breast Cancer Res Treat 90:85-91. 2005
    ..The objective of this prospective study was to assess the oncological and functional outcomes in breast cancer patients after endoscopic ALND...
  18. ncbi request reprint Non-inferiority trials in surgical oncology
    Philipp Fueglistaler
    Department of Surgery, Divisions of General Surgery and Surgical Research, University of Basel, Basel, Switzerland
    Ann Surg Oncol 14:1532-9. 2007
    ..The goal of this review is to discuss the principles, strengths, and challenges of non-inferiority trials and introduce this highly relevant topic to the surgical reader, using examples from the field of surgical oncology...
  19. ncbi request reprint Influence of provider volume on length of stay, operating room time, and discharge status for rotator cuff repair
    Nitin B Jain
    Center for Excellence in Surgical Outcomes, Durham, NC, USA
    J Shoulder Elbow Surg 14:407-13. 2005
    ..The mean operating room times for low- and intermediate-volume surgeons were significantly higher than that for high-volume surgeons (P < .001). We conclude that high-volume providers use health care resources more efficiently...
  20. ncbi request reprint Early introduction of laparoscopic sigmoid colectomy during residency
    S Daetwiler
    Department of Surgery, Spital Limmattal, Schlieren, Switzerland
    Br J Surg 94:634-41. 2007
    ..However, few residency programmes incorporate the procedure. This study evaluated the safety and feasibility of the early introduction of laparoscopic sigmoid colectomy during residency...
  21. ncbi request reprint Association of the presence of bone marrow micrometastases with the sentinel lymph node status in 410 early stage breast cancer patients: results of the Swiss Multicenter Study
    Igor Langer
    Department of Surgery, University Hospital Basel, Basel, Switzerland
    Ann Surg Oncol 14:1896-903. 2007
    ..It is unknown whether an association exists between the SLN status and the presence of bone marrow (BM) micrometastases. The objective of the present investigation was to evaluate whether or not such an association exists...
  22. doi request reprint Interdisciplinary tumour boards in Switzerland: quo vadis?
    Kuno Lehmann
    Department of Surgery, Kantonsspital Olten, Olten, Switzerland
    Swiss Med Wkly 138:123-7. 2008
    ....
  23. doi request reprint Accuracy of frozen section of sentinel lymph nodes: a prospective analysis of 659 breast cancer patients of the Swiss multicenter study
    Igor Langer
    Division of General Surgery, University Hospital Basel, Basel, Switzerland
    Breast Cancer Res Treat 113:129-36. 2009
    ..To assess the accuracy of sentinel lymph node (SLN) frozen section in a prospective multicenter study of early-stage breast cancer patients...
  24. pmc Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN and completion axillary lymph node dissection after breast cancer surgery: a prospective Swiss multicenter study on 659 patients
    Igor Langer
    Department of Surgery, University Hospital Basel, Basel, Switzerland
    Ann Surg 245:452-61. 2007
    ..To assess the morbidity after sentinel lymph node (SLN) biopsy compared with SLN and completion level I and II axillary lymph node dissection (ALND) in a prospective multicenter study...
  25. ncbi request reprint Sample size matters: a guide for surgeons
    Ulrich Guller
    Department of Surgery, Divisions of General Surgery and Surgical Research, University of Basel, Spitalstrasse 21, CH 4031, Basel, Switzerland
    World J Surg 29:601-5. 2005
    ....
  26. ncbi request reprint Provider Volume of Total Knee Arthroplasties and Patient Outcomes in the HCUP-Nationwide Inpatient Sample
    Sheleika L Hervey
    Department of Surgery, Division of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Bone Joint Surg Am 85:1775-83. 2003
    ..We hypothesized that surgeons and hospitals with higher patient volumes would have better outcomes, as defined by lower mortality rates, shorter hospital stays, and lower postoperative complication rates...
  27. ncbi request reprint Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet!
    Ulrich Guller
    Department of Surgery, University of Basel, Switzerland
    Breast Cancer Res Treat 71:171-3. 2002
    ..Selective axillary surgery in breast cancer patients based on 18F-FDG PET is yet not possible...
  28. pmc Laparoscopic versus open appendectomy: outcomes comparison based on a large administrative database
    Ulrich Guller
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Surg 239:43-52. 2004
    ..To compare length of hospital stay, in-hospital complications, in-hospital mortality, and rate of routine discharge between laparoscopic and open appendectomy based on a representative, nationwide database...
  29. ncbi request reprint Is positron emission tomography an accurate non-invasive alternative to sentinel lymph node biopsy in breast cancer patients?
    Ulrich Guller
    Dept of Surgery, University of Basel, Basel, Switzerland
    J Natl Cancer Inst 95:1040-3. 2003
  30. pmc Axillary recurrence rate in breast cancer patients with negative sentinel lymph node (SLN) or SLN micrometastases: prospective analysis of 150 patients after SLN biopsy
    Igor Langer
    Department of Surgery, University of Basel, Switzerland
    Ann Surg 241:152-8. 2005
    ..2 mm to <or=2.0 mm) after breast surgery and SLN procedure without formal axillary lymph node dissection (ALND)...
  31. ncbi request reprint Laparoscopic vs open colectomy: outcomes comparison based on large nationwide databases
    Ulrich Guller
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Arch Surg 138:1179-86. 2003
    ..Laparoscopic colectomy has significant advantages over open colectomy in the treatment of diverticular disease with respect to the length of hospital stay, routine hospital discharge, and postoperative morbidity and mortality...
  32. ncbi request reprint Outcomes of early extubation after bypass surgery in the elderly
    Ulrich Guller
    Department of Surgery, University of Alabama School of Medicine, Birmingham, Alabama, USA
    Ann Thorac Surg 77:781-8. 2004
    ..The goal of the present investigation was to evaluate whether early extubation can be performed safely in elderly CABG patients in community practice...
  33. ncbi request reprint Total arthroplasty versus hemiarthroplasty for glenohumeral osteoarthritis: role of provider volume
    Nitin B Jain
    Center for Excellence in Surgical Outcomes, Durham, NC, USA
    J Shoulder Elbow Surg 14:361-7. 2005
    ..Definitive treatment guidelines for glenohumeral osteoarthritis are needed...
  34. doi request reprint Effect of the 50-hour workweek limitation on training of surgical residents in Switzerland
    Adrian Businger
    Department of General Surgery and Surgical Research, University Hospital Basel, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Arch Surg 145:558-63. 2010
    ..The 50-hour workweek limitation for surgical residents in Switzerland has a major effect on surgical training, resident quality of life, and patient care...
  35. pmc Disseminated single tumor cells as detected by real-time quantitative polymerase chain reaction represent a prognostic factor in patients undergoing surgery for colorectal cancer
    Ulrich Guller
    Surgical Research Unit, Deparment of Surgery, University of Basel, Switzerland
    Ann Surg 236:768-75; discussion 775-6. 2002
    ....
  36. doi request reprint Axillary lymph node dissection for sentinel lymph node micrometastases may be safely omitted in early-stage breast cancer patients: long-term outcomes of a prospective study
    Igor Langer
    Department of Surgery, University Hospital Lausanne, Lausanne, Switzerland
    Ann Surg Oncol 16:3366-74. 2009
    ..To evaluate the long-term disease-free and overall survival of patients with sentinel lymph node (SLN) micrometastases, in whom a completion axillary lymph node dissection (ALND) was systematically omitted...
  37. ncbi request reprint Laparoscopic appendectomy in the elderly
    Ulrich Guller
    Department of Surgery, the Center for Excellence in Surgical Outcomes, Duke University Medical Center, Durham, NC, USA
    Surgery 135:479-88. 2004
    ..Evidence suggests that laparoscopic appendectomy (LA) has advantages over open appendectomy (OA) in the treatment of appendicitis. It remains, however, unclear whether LA is indicated in the elderly patient population...
  38. ncbi request reprint Stage-specific effect of adjuvant therapy following gastric cancer resection: a population-based analysis of 4,041 patients
    Natalie G Coburn
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Ann Surg Oncol 15:500-7. 2008
    ..Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population...
  39. ncbi request reprint Cryotherapy after ACL reconstruction: a meta-analysis
    Mathew C Raynor
    School of Medicine, University of North Carolina at Chapel Hill, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Knee Surg 18:123-9. 2005
    ....
  40. ncbi request reprint Effect of provider volume on resource utilization for surgical procedures of the knee
    Nitin Jain
    Center for Excellence in Surgical Outcomes, Duke University Medical Center, Durham, NC, USA
    Knee Surg Sports Traumatol Arthrosc 13:302-12. 2005
    ..001). High-volume providers utilize healthcare resources more efficiently. Our findings may help surgeons and hospitals in optimizing resource utilization and cost for routinely-performed ambulatory surgery procedures...
  41. ncbi request reprint Trends in the epidemiology of total shoulder arthroplasty in the United States from 1990-2000
    Nitin B Jain
    Duke University Medical Center, Durham, North Carolina, USA
    Arthritis Rheum 55:591-7. 2006
    ..We evaluated trends in the distribution of age, race, hospital volume and teaching status, outcomes, and indications for TSA during the last decade...
  42. ncbi request reprint Trends in epidemiology of knee arthroplasty in the United States, 1990-2000
    Nitin B Jain
    Duke University Medical Center, Durham, North Carolina, USA
    Arthritis Rheum 52:3928-33. 2005
    ....
  43. ncbi request reprint NY-ESO-1/LAGE-1 coexpression with MAGE-A cancer/testis antigens: a tissue microarray study
    Martin Bolli
    Institut Chirurgische Forschung und Spitalmanagement, Department Forschung, University of Basel, Switzerland
    Int J Cancer 115:960-6. 2005
    ..Taken together, these data suggest novel areas of application of C/T antigens targeted active specific immunotherapy possibly based on multiantigen vaccine preparations...
  44. ncbi request reprint Insurance status and race represent independent predictors of undergoing laparoscopic surgery for appendicitis: secondary data analysis of 145,546 patients
    Ulrich Guller
    Department of Surgery, Division of General Surgery, University of Basel Switzerland
    J Am Coll Surg 199:567-75; discussion 575-7. 2004
    ..Studies have shown that racial and socioeconomic differences lead to inequality in access to health care. It is unknown whether insurance status and race affect the choice of surgical treatment for patients presenting with appendicitis...
  45. ncbi request reprint Heterologous prime-boost immunotherapy of melanoma patients with Influenza virosomes, and recombinant Vaccinia virus encoding 5 melanoma epitopes and 3 co-stimulatory molecules. A multi-centre phase I/II open labeled clinical trial
    Michel Adamina
    Institute for Surgical Research and Hospital Management, Department of Surgery, University of Basel, Hebelstrasse 20, 4031 Basel, Switzerland
    Contemp Clin Trials 29:165-81. 2008
    ..Disease free survival will be assessed by 4-monthly serial clinic visits, including physical and FDG-PET examinations, for a follow-up time of 2 years. Quality of life will be assessed with a dedicated FACT-BRM 4 questionnaire...
  46. ncbi request reprint The relationship between surgeon and hospital volume and outcomes for shoulder arthroplasty
    Nitin Jain
    VA Boston Healthcare System, 1400 VFW Parkway, Pulmonary IIIB, West Roxbury, MA 02132, USA
    J Bone Joint Surg Am 86:496-505. 2004
    ....
  47. ncbi request reprint Interpreting statistics in medical literature: a vade mecum for surgeons
    Ulrich Guller
    Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA
    J Am Coll Surg 198:441-58. 2004
  48. ncbi request reprint Randomized controlled trials do not reflect reality: real-world analyses are critical for treatment guidelines!
    Martin T R Grapow
    J Thorac Cardiovasc Surg 132:5-7. 2006
  49. ncbi request reprint Does hypervascularity of liver metastases as detected on MRI predict disease progression in breast cancer patients?
    Larissa Braga
    Department of Radiology, University of North Carolina at Chapel Hill, Manning Dr, Chapel Hill, NC 27599 7510, USA
    AJR Am J Roentgenol 182:1207-13. 2004
    ..The aim of our study was to evaluate the association of the vascularity of liver metastases, as characterized by MRI, and disease progression in breast cancer patients...