[Electroconvulsive shock causes neuronal death in the mouse hippocampus: correlation of neurodegeneration and convulsive activity]I I Zarubenko
Institute of Higher Nervous Activity and Neurophysiology, Russian Acad. Sci, Moscow 117485, Russia
Ross Fiziol Zh Im I M Sechenova 90:272-81. 2004
..The inverse correlation of cell number with severity of seizures suggest that these are seizures inducing neuronal death...
[Effects of central administration of beta-amyloid peptide (25-35): pathomorphological changes in the hippocampus and impairments of spatial memory]M Iu Stepanichev
Zh Vyssh Nerv Deiat Im I P Pavlova 54:705-11. 2004
..The results are the first evidence for a specific relationship between neurodegeneration in the CA1 subfield of rat hippocampus and impairments of learning and memory induced by Abeta(25-35)...
"Apoptotic" mechanisms in normal brain plasticity: caspase-3 and long-term potentiationN V Guliaeva
Department of Functional Biochemistry of the Nervous System, Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia
Zh Vyssh Nerv Deiat Im I P Pavlova 54:437-47. 2004
..A concept on a new mechanism of synaptic plasticity modulation involving caspase-3 has been formulated postulating a specific role of caspase-3 in normal brain functioning...
Caspase activity is essential for long-term potentiationNatalia V Gulyaeva
Department of Functional Biochemistry of the Nervous System, Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia
J Neurosci Res 73:853-64. 2003
..Candidate caspase-3 substrates that may be cleaved for LTP induction and maintenance are discussed...
[Caspase-3 inhibition blocks long-term potentiation in hippocampal slices]I E Kudriashov
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow
Zh Vyssh Nerv Deiat Im I P Pavlova 53:537-40. 2003
..The results are the first evidence for the involvement of caspase-3-mediated mechanisms in long-term potentiation phenomenon...
[Administration of aggregated beta-amyloid peptide (25-35) causes change in long-term potentiation in the hippocampus]V V Trubetskaia
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow
Zh Vyssh Nerv Deiat Im I P Pavlova 51:690-3. 2001
..This phenomenon can be related with the oxidative stress that was revealed in this model in our previous studies, and, as a consequence, with deterioration of ion homeostasis...
[Effect of impulse extrabroad-band electromagnetic radiation on electroencephalogram and sleep in laboratory animals]E V Petrova
Institute of Higher Nervous Activity and Neurophysiology, Russian Acad. Sci, Russia, 117865, Moscow
Ross Fiziol Zh Im I M Sechenova 89:786-94. 2003
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[Pentylenetetrazole kindling induces caspase-3 activation in rat brain]T V Pavlova
Institute of Higher Nervous Activity, Russian Academy of Sciences, Moscow
Zh Vyssh Nerv Deiat Im I P Pavlova 53:110-2. 2003
..The number of neurons in the CA3 subfield of the hippocampus decreased significantly, whereas no apoptotic nuclei could be detected. The results support a possible non-apoptotic involvement of caspase-3 in brain plasticity...
[Effects of caspase-3 inhibition on long-term potentiation in the hippocampus: analysis of paired pulse facilitation]I V Kudriashova
Ross Fiziol Zh Im I M Sechenova 91:915-26. 2005
..The Caspase inhibition seems to prevent structural reorganization during the LTP related to involvement into the response of new synapses and neurons...
[Effects of intracerebroventricular administration of a caspase-3 inhibitor Z-DEVD-FMK on behavior of rats]M Iu Stapanichev
Zh Vyssh Nerv Deiat Im I P Pavlova 56:247-56. 2006
..The results suggest the involvement of brain caspase-3 in selected forms of learning...
[Caspase-3 activity in the rat hippocampal slices reflects changes in synaptic plasticity]I V Kudriashova
Ross Fiziol Zh Im I M Sechenova 94:3-13. 2008
..Our data suggest that high caspase-3 activity in hippocampal slices is involved in maintenance of synaptic plasticity but not necessarily related to apoptosis...
[Anxiety level during morphine abstinence correlates with the status of nitrergic system in the rat hippocampus]D I Peregud
Ross Fiziol Zh Im I M Sechenova 93:357-65. 2007
..The data suggest that nitrergic system changes in the hippocampus may be involved in molecular mechanisms of behavioural alteration during morphine abstinence in rats...
[Kindling during early postnatal development: the effects on the maturation of the hippocampal electrophysiological characteristics]I E Kudriashov
Zh Vyssh Nerv Deiat Im I P Pavlova 56:706-14. 2006
..These modifications did not correlate with convulsive activity. A significant correlation with convulsive activity was found only for population spike amplitudes evoked by low, near-threshold stimuli...
[Pentylenetetrazole kindling in rats: whether neurodegeneration is associated with manifestations of seizure activity?]T V Pavlova
Ross Fiziol Zh Im I M Sechenova 91:764-75. 2005
..The results suggest that, in PTZ kindling model, oxidative damage of neurons resulting in neurodegeneration in hippocampus is not directly related to the convulsive activity...
[Developmental caspase-3 activation in the rat hippocampus is involved in the maturation of instrumental behavior]I V Kudriashova
Zh Vyssh Nerv Deiat Im I P Pavlova 57:702-11. 2007
..The change of exploratory behavior is unlikely to be specific for caspase-3 inhibition, being similar in Z-DEVD-FMK and Z-FA-FMK groups...