Maya Guglin

..We sought to determine if there is a disparity in their utilization compared with ACE inhibitors and beta-adrenoceptor antagonists (beta-blockers)...

..In this article we review the existing literature on the use of ultrafiltration for treating volume overload states in patients with heart failure...

..Renal dysfunction in heart failure is thought to be due to poor perfusion of the kidney...

..Most importantly, myocarditis can transition to non-ischemic cardiomyopathy with eventually poor outcome. In this review, we will summarize the data on different diagnostic and treatment modalities of this disease...

..In summary, cardiac diastolic pressures and corresponding echocardiographic parameters, as well as hematocrit level, predicted RV systolic function in both compensated and decompensated systolic HF...

..In that trial, subjective and objective data were recorded at multiple time points when HB and HCT were also measured. We investigated the relationship between anemia and ventricular systolic function...

..Being the driving force of heart failure, congestion should be the focus of clinical and hemodynamic monitoring and therapy...

..While some protocols involve extensive several-day testing both at rest and with exercise, others are mostly guided by echocardiographic evaluation...

..With the expansion of CRT indications to minimally symptomatic or asymptomatic patients, the benefit of device therapy must be carefully weighed against the potential risk of lifelong device complications...

..Mechanical support is also examined. Finally, this review places an emphasis on RV failure in the setting of left ventricular assist devices and heart transplantation...

..Current definition of stress-induced cardiomyopathy includes only regional wall motion abnormalities. It should be expanded to include all varieties of wall motion abnormalities including global hypokinesis...

..Ongoing trials will demonstrate whether the indication for aldosterone antagonists can be expanded to less severe heart failure or patients with preserved systolic function...

..Serum creatinine level correlated with BNP level, but neither age nor sex did. High BNP level (4000-20,000 pg/mL) is determined more by renal dysfunction than by the severity of heart failure...

..However, AF is associated with greater morbidity and mortality and poorer functional status than sinus rhythm, which is more likely to be achieved with a rhythm control strategy...

..Studies with prospective data collection and thorough analyses are needed to establish a causal relationship between certain anticancer drugs and arrhythmia...

..In conclusion, obesity is associated with a higher incidence of recurrence of AF and greater AF burden...

..Cardiotoxicity of aggressive chemotherapeutic regimens includes cardiomyopathy and arrhythmias. Although cardiomyopathy is a well-recognized entity, arrhythmias are poorly studied...

..However, a major side effect of this medication is cardiomyopathy. Our objective was to determine the incidence of trastuzumab-induced cardiomyopathy and the rate of discontinuation of trastuzumab in a clinical setting...

....

..This article reviews the etiology and natural history of anthracycline-induced cardiotoxicity and provides options available for limiting and/or preventing cardiotoxicity...

..Extreme values of BNP do not necessarily correlate with the presence of HF, cardiomyopathy, or kidney dysfunction. When the magnitude of BNP elevation is very high, its clinical significance is limited...

..Pulmonary hypertension occurs in 60% to 80% of patients with heart failure and is associated with high morbidity and mortality...

..Future trials will show whether the use of these drugs translates to decreased morbidity and mortality in heart failure...

..We conclude that existing evidence is sufficient to recognize that diuretics are essential for the management of HF. Selection bias is the likely source of their connection to poor outcomes...

..It is unknown how right ventricular dysfunction influences the accuracy of ECHO-derived estimation of pulmonary hypertension in patients with severe left ventricular systolic dysfunction...

..3DTTE should be utilized in cases of new onset heart failure with unclear etiology to diagnose unusual causes of this potentially fatal condition...

....

..We searched PubMed for trials involving trastuzumab used as an adjuvant therapy for breast cancer, including the metastatic breast cancer setting, and focused on cardiotoxicity...

..Stress-induced cardiomyopathy may present in different forms, including regional or global left ventricular dysfunction. Classic takotsubo syndrome may represent only part of the spectrum of this reversible condition...

..Ongoing clinical trials should further define the scope of the potential therapeutic role of VRAs...