Sigurdur Gudjonsson

Summary

Publications

  1. doi request reprint The value of bladder mapping and prostatic urethra biopsies for detection of carcinoma in situ (CIS)
    Sigurdur Gudjonsson
    Department of Urology, Skane University Hospital, Malmo, Sweden
    BJU Int 110:E41-5. 2012
  2. doi request reprint Can tissue microarray-based analysis of protein expression predict recurrence of stage Ta bladder cancer?
    Sigurdur Gudjonsson
    Department of Urology, Skane University Hospital, Malmo, Sweden
    Scand J Urol Nephrol 45:270-7. 2011
  3. doi request reprint Should all patients with non-muscle-invasive bladder cancer receive early intravesical chemotherapy after transurethral resection? The results of a prospective randomised multicentre study
    Sigurdur Gudjonsson
    Lund University Hospital, Lund, Sweden
    Eur Urol 55:773-80. 2009
  4. pmc Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma
    David Lindgren
    Department of Molecular Pathology, Lund University, Malmo, Sweden
    PLoS ONE 7:e38863. 2012
  5. doi request reprint Tissue microarray based analysis of prognostic markers in invasive bladder cancer: much effort to no avail?
    Fredrik Liedberg
    Department of Urology, Lund University Hospital, Lund, Sweden
    Urol Oncol 26:17-24. 2008
  6. pmc DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status
    Martin Lauss
    Department of Oncology, Clinical Sciences, Skane University Hospital, Lund University, Lund, Sweden
    Epigenetics 7:858-67. 2012
  7. pmc Recurrent and multiple bladder tumors show conserved expression profiles
    David Lindgren
    Department of Clinical Genetics, Lund University Hospital, Lund, Sweden
    BMC Cancer 8:183. 2008
  8. doi request reprint Toward a molecular pathologic classification of urothelial carcinoma
    Gottfrid Sjödahl
    Department of Clinical Sciences, Division of Oncology, Skane University Hospital, Lund University, Lund, Sweden
    Am J Pathol 183:681-91. 2013
  9. ncbi request reprint Prospective study of transitional cell carcinoma in the prostatic urethra and prostate in the cystoprostatectomy specimen. Incidence, characteristics and preoperative detection
    Fredrik Liedberg
    Department of Urology, Lund University Hospital, Lund, Sweden
    Scand J Urol Nephrol 41:290-6. 2007
  10. doi request reprint A molecular taxonomy for urothelial carcinoma
    Gottfrid Sjödahl
    Department of Oncology, Clinical Sciences, Lund University Hospital, Lund University, Lund, Sweden
    Clin Cancer Res 18:3377-86. 2012

Collaborators

Detail Information

Publications19

  1. doi request reprint The value of bladder mapping and prostatic urethra biopsies for detection of carcinoma in situ (CIS)
    Sigurdur Gudjonsson
    Department of Urology, Skane University Hospital, Malmo, Sweden
    BJU Int 110:E41-5. 2012
    ....
  2. doi request reprint Can tissue microarray-based analysis of protein expression predict recurrence of stage Ta bladder cancer?
    Sigurdur Gudjonsson
    Department of Urology, Skane University Hospital, Malmo, Sweden
    Scand J Urol Nephrol 45:270-7. 2011
    ..Tissue microarray (TMA)-based analysis of Ta bladder tumours was used to investigate the prognostic value of expression of several proteins involved in bladder carcinogenesis...
  3. doi request reprint Should all patients with non-muscle-invasive bladder cancer receive early intravesical chemotherapy after transurethral resection? The results of a prospective randomised multicentre study
    Sigurdur Gudjonsson
    Lund University Hospital, Lund, Sweden
    Eur Urol 55:773-80. 2009
    ....
  4. pmc Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma
    David Lindgren
    Department of Molecular Pathology, Lund University, Malmo, Sweden
    PLoS ONE 7:e38863. 2012
    ..Taken together, our integrative approach revealed at least two separate networks of genomic alterations linked to the molecular diversity seen in UC, and that these circuits may reflect distinct pathways of tumor development...
  5. doi request reprint Tissue microarray based analysis of prognostic markers in invasive bladder cancer: much effort to no avail?
    Fredrik Liedberg
    Department of Urology, Lund University Hospital, Lund, Sweden
    Urol Oncol 26:17-24. 2008
    ..To evaluate altered protein expression with tissue microarray methodology for 15 different markers with potential prognostic significance in invasive bladder cancer...
  6. pmc DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status
    Martin Lauss
    Department of Oncology, Clinical Sciences, Skane University Hospital, Lund University, Lund, Sweden
    Epigenetics 7:858-67. 2012
    ..Our data highlights HOX gene silencing and EZH2 expression as mechanisms to promote a more undifferentiated and aggressive state in UC...
  7. pmc Recurrent and multiple bladder tumors show conserved expression profiles
    David Lindgren
    Department of Clinical Genetics, Lund University Hospital, Lund, Sweden
    BMC Cancer 8:183. 2008
    ..Consequently, genetically less evolved tumors may appear chronologically later than genetically related but more evolved tumors...
  8. doi request reprint Toward a molecular pathologic classification of urothelial carcinoma
    Gottfrid Sjödahl
    Department of Clinical Sciences, Division of Oncology, Skane University Hospital, Lund University, Lund, Sweden
    Am J Pathol 183:681-91. 2013
    ..These three major subtypes exhibit important prognostic differences. ..
  9. ncbi request reprint Prospective study of transitional cell carcinoma in the prostatic urethra and prostate in the cystoprostatectomy specimen. Incidence, characteristics and preoperative detection
    Fredrik Liedberg
    Department of Urology, Lund University Hospital, Lund, Sweden
    Scand J Urol Nephrol 41:290-6. 2007
    ....
  10. doi request reprint A molecular taxonomy for urothelial carcinoma
    Gottfrid Sjödahl
    Department of Oncology, Clinical Sciences, Lund University Hospital, Lund University, Lund, Sweden
    Clin Cancer Res 18:3377-86. 2012
    ..An extension of this approach would be to base tumor classification primarily on molecular features. Here, we present a molecular taxonomy for urothelial carcinoma based on integrated genomics...
  11. doi request reprint Combined gene expression and genomic profiling define two intrinsic molecular subtypes of urothelial carcinoma and gene signatures for molecular grading and outcome
    David Lindgren
    Department of Clinical Sciences, Oncology, Lund University, Lund, Sweden
    Cancer Res 70:3463-72. 2010
    ..We conclude that the combination of molecular and histopathologic classification systems might provide a strong improvement for bladder cancer classification and produce new insights into the development of this tumor type...
  12. pmc A systematic study of gene mutations in urothelial carcinoma; inactivating mutations in TSC2 and PIK3R1
    Gottfrid Sjödahl
    Department of Clinical Sciences, Oncology, Lund University, Skane University Hospital, Lund, Sweden
    PLoS ONE 6:e18583. 2011
    ..g., PIK3CA, AKT1, and RAS. Most mutation studies of UCs have been focused on single or a few genes at the time or been performed on small sample series. This has limited the possibility to investigate co-occurrence of mutations...
  13. doi request reprint Preoperative staging of locally advanced bladder cancer before radical cystectomy using 3 tesla magnetic resonance imaging with a standardized protocol
    Fredrik Liedberg
    Department of Urology, Lund University, Malmo, Sweden
    Scand J Urol 47:108-12. 2013
    ..The aim of this study was to compare tumour stage at MRI with pathological tumour stage in the cystectomy specimen...
  14. doi request reprint MiRNA expression in urothelial carcinomas: important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31
    Srinivas Veerla
    Department of Clinical Genetics, Lund University Hospital, Lund, Sweden
    Int J Cancer 124:2236-42. 2009
    ..In addition, these latter miRNAs were shown to be excellent prognostic markers for death by disease as outcome. The presented data shows that pathological subtypes of urothelial carcinoma show distinct miRNA gene expression signatures...
  15. doi request reprint Extended lymph node dissection in patients with urothelial cell carcinoma of the bladder: can it make a difference?
    Magnus Holmer
    Department of Urology, Lund University Hospital, 221 85 Lund, Sweden
    World J Urol 27:521-6. 2009
    ..We compared extended and limited lymph node dissections performed during radical cystectomy with regard to impact on survival and time to recurrence in bladder cancer patients...
  16. doi request reprint Extended pelvic lymphadenectomy for prostate cancer: will the previously reported benefits be reproduced in hospitals with lower surgical volumes?
    Christian Lindberg
    Department of Urology, Lund University Hospital, Lund, Sweden
    Scand J Urol Nephrol 43:437-41. 2009
    ..However, these studies were from high-volume centres. This study investigated whether these results could be repeated in a hospital with lower surgical volume, more typical for the Nordic countries...
  17. ncbi request reprint The value of the UroVysion assay for surveillance of non-muscle-invasive bladder cancer
    Sigurdur Gudjonsson
    Lund University Hospital, Department of Urology, Lund, Sweden
    Eur Urol 54:402-8. 2008
    ..A fluorescence in situ hybridisation technique called UroVysion (UV) is now available for clinical diagnosis of urothelial cancer cells. The aim of the present study was to compare UV analysis with routine follow-up methods...
  18. ncbi request reprint Intraoperative sentinel node detection improves nodal staging in invasive bladder cancer
    Fredrik Liedberg
    Department of Urology, Lund University Hospital, Lund, Sweden
    J Urol 175:84-8; discussion 88-9. 2006
    ..We evaluated intraoperative SN detection in patients with invasive bladder cancer during radical cystectomy in conjunction with extended lymphadenectomy...
  19. ncbi request reprint Distinct mitotic segregation errors mediate chromosomal instability in aggressive urothelial cancers
    Yuesheng Jin
    Department of Clinical Genetics, Lund University Hospital, Lund, Sweden
    Clin Cancer Res 13:1703-12. 2007
    ..The aim of this study was to evaluate whether disturbances of mitotic segregation contribute to CIN in UC, if these processes have any effect on the course of disease, and how deregulation of these mechanisms affects tumor cell growth...