Frank Guarnieri

Summary

Publications

  1. pmc A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema
    Frank Guarnieri
    Paka Pulmonary Pharmaceuticals, Acton, MA 01720, USA
    Proc Natl Acad Sci U S A 107:10661-6. 2010

Detail Information

Publications1

  1. pmc A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema
    Frank Guarnieri
    Paka Pulmonary Pharmaceuticals, Acton, MA 01720, USA
    Proc Natl Acad Sci U S A 107:10661-6. 2010
    ..Covalently combining an endogenous peptide from the target organ with a synthetic small molecule inhibitor is a unique way of endowing an active compound with the pharmacodynamic profile needed to create in vivo efficacy...