Ting Lei Gu

Summary

Publications

  1. ncbi Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
    Ting Lei Gu
    Cell Signaling Technology, Danvers, Massachusetts, United States of America
    PLoS ONE 6:e15640. 2011
  2. ncbi Survey of activated FLT3 signaling in leukemia
    Ting Lei Gu
    Cell Signaling Technology, Inc, Danvers, Massachusetts, United States of America
    PLoS ONE 6:e19169. 2011
  3. ncbi Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia
    Ting Lei Gu
    Cell Signaling Technology, Inc, 3 Trask Lane, Danvers, MA 01923, USA
    Blood 108:4202-4. 2006
  4. ncbi Identification of anaplastic lymphoma kinase as a potential therapeutic target in ovarian cancer
    Hong Ren
    Cell Signaling Technology, Inc, Danvers, Massachusetts 01923, USA
    Cancer Res 72:3312-23. 2012
  5. ncbi Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion
    Victoria M Rimkunas
    Cell Signaling Technology, Danvers, MA, USA
    Clin Cancer Res 18:4449-57. 2012
  6. ncbi A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia
    Ting Lei Gu
    Cell Signaling Technology, Danvers, MA 01923, USA
    Blood 110:323-33. 2007
  7. ncbi Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    Klarisa Rikova
    Cell Signaling Technology, 3 Trask Lane, Danvers, MA 01923, USA
    Cell 131:1190-203. 2007
  8. ncbi Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells
    Melodie L Knowlton
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e13587. 2010

Collaborators

  • Yi Wang
  • Jian Yu
  • Judit Villen
  • Denise K Walters
  • Jeffrey W Tyner
  • Yi Zhang
  • Masanori Daibata
  • Bryan A Ballif
  • Hongwei Li
  • D Gary Gilliland
  • Yu Li
  • Herbert Haack
  • Victoria M Rimkunas
  • Hong Ren
  • Melodie L Knowlton
  • Michael J Comb
  • Yerong Hu
  • Xinmin Zhou
  • Jian Min Ren
  • John Rush
  • Daiqiang Li
  • Steven P Gygi
  • Klarisa Rikova
  • Xin min Zhou
  • Matthew R Silver
  • Katherine E Crosby
  • Yi Feng Yang
  • Xin Zhu
  • Katherine Crosby
  • Sean Beausoleil
  • Meghan E Kelly
  • Zhi Ping Tan
  • Albrecht Moritz
  • Jennifer S Mack
  • Gregory Innocenti
  • Carolyn N Wrobel
  • Roberto Polakiewicz
  • Joan S Brugge
  • Laura M Selfors
  • Matthew Stokes
  • Cynthia Reeves
  • Joan Macneill
  • Ailan Guo
  • Julie Nardone
  • Qingfu Zeng
  • Anthony Possemato
  • Jin Yuan
  • Randy Wetzel
  • Jon M Kornhauser
  • Corey E Bakalarski
  • Kimberly Lee
  • Roberto D Polakiewicz
  • Jeffrey Mitchell
  • Zhiping Tan
  • Laura Sullivan
  • Bradley Smith

Detail Information

Publications8

  1. ncbi Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
    Ting Lei Gu
    Cell Signaling Technology, Danvers, Massachusetts, United States of America
    PLoS ONE 6:e15640. 2011
    ....
  2. ncbi Survey of activated FLT3 signaling in leukemia
    Ting Lei Gu
    Cell Signaling Technology, Inc, Danvers, Massachusetts, United States of America
    PLoS ONE 6:e19169. 2011
    ..It provides a valuable resource for investigation of oncogenic FLT3 signaling in human leukemia...
  3. ncbi Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia
    Ting Lei Gu
    Cell Signaling Technology, Inc, 3 Trask Lane, Danvers, MA 01923, USA
    Blood 108:4202-4. 2006
    ..Thus, the KG-1 cell line provides an in vitro model for the study of FGFR1 fusions associated with leukemia and for the analysis of small molecule inhibitors against FGFR1 fusions...
  4. ncbi Identification of anaplastic lymphoma kinase as a potential therapeutic target in ovarian cancer
    Hong Ren
    Cell Signaling Technology, Inc, Danvers, Massachusetts 01923, USA
    Cancer Res 72:3312-23. 2012
    ..Our findings provide new insights into the pathogenesis of ovarian cancer and identify ALK as a potential therapeutic target in a subset of serous ovarian carcinoma and stromal sarcoma patients...
  5. ncbi Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion
    Victoria M Rimkunas
    Cell Signaling Technology, Danvers, MA, USA
    Clin Cancer Res 18:4449-57. 2012
    ....
  6. ncbi A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia
    Ting Lei Gu
    Cell Signaling Technology, Danvers, MA 01923, USA
    Blood 110:323-33. 2007
    ..These findings identify a novel potential therapeutic target in leukemogenesis, and demonstrate the utility of phosphoproteomic strategies for discovery of tyrosine kinase alleles...
  7. ncbi Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    Klarisa Rikova
    Cell Signaling Technology, 3 Trask Lane, Danvers, MA 01923, USA
    Cell 131:1190-203. 2007
    ..By focusing on activated cell circuitry, the approach outlined here provides insight into cancer biology not available at the chromosomal and transcriptional levels and can be applied broadly across all human cancers...
  8. ncbi Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells
    Melodie L Knowlton
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e13587. 2010
    ..In summary, our data reveal quantitative site-specific changes in tyrosine phosphorylation induced by CSF-1R activation in epithelial cells and identify many candidate SRC-dependent substrates phosphorylated downstream of an RTK...