M Grupe

Summary

Publications

  1. doi request reprint Neuropharmacological modulation of the P3-like event-related potential in a rat two-tone auditory discrimination task with modafinil and NS9283, a positive allosteric modulator of α4β2 nAChRs
    Morten Grupe
    Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark Synaptic Transmission 1, H Lundbeck A S, Ottiliavej 9, 2500 Valby, Denmark Electronic address
    Neuropharmacology 79:444-55. 2014
  2. doi request reprint Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats
    Morten Grupe
    Department of Psychology and Neuroscience Program, University of Michigan, 530 Church Street, 4030 East Hall, Ann Arbor, MI 48109 1109, USA Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark NeuroSearch A S, Pederstrupvej 93, 2750 Ballerup, Denmark Electronic address
    Biochem Pharmacol 86:1487-96. 2013
  3. pmc Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors
    M Grupe
    Neurosearch A S, Ballerup, Denmark
    Br J Pharmacol 168:2000-10. 2013

Collaborators

Detail Information

Publications3

  1. doi request reprint Neuropharmacological modulation of the P3-like event-related potential in a rat two-tone auditory discrimination task with modafinil and NS9283, a positive allosteric modulator of α4β2 nAChRs
    Morten Grupe
    Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark Synaptic Transmission 1, H Lundbeck A S, Ottiliavej 9, 2500 Valby, Denmark Electronic address
    Neuropharmacology 79:444-55. 2014
    ..These findings encourage further exploration of the rat P3-like ERP in order to promote the understanding of its meaning within cognition, as well as its applicability as a translatable biomarker in drug development. ..
  2. doi request reprint Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats
    Morten Grupe
    Department of Psychology and Neuroscience Program, University of Michigan, 530 Church Street, 4030 East Hall, Ann Arbor, MI 48109 1109, USA Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark NeuroSearch A S, Pederstrupvej 93, 2750 Ballerup, Denmark Electronic address
    Biochem Pharmacol 86:1487-96. 2013
    ....
  3. pmc Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors
    M Grupe
    Neurosearch A S, Ballerup, Denmark
    Br J Pharmacol 168:2000-10. 2013
    ..In this study, we present a detailed electrophysiological characterization of NS9283, a potent positive allosteric modulator acting selectively at 3α:2β stoichiometry of α2* and α4* nAChRs...