Wittmann D, Kløve S, Wang P, Grimm B. Towards Initial Indications for a Thiol-Based Redox Control of Arabidopsis 5-Aminolevulinic Acid Dehydratase. Antioxidants (Basel). 2018;7: pubmed publisher
..From our results it was concluded that (i) deficiency of the reducing power mainly affected the in planta stability of ALAD; and (ii) the reduced form of ALAD displayed increased enzymatic activity. ..
Wang P, Grimm B. Organization of chlorophyll biosynthesis and insertion of chlorophyll into the chlorophyll-binding proteins in chloroplasts. Photosynth Res. 2015;126:189-202 pubmed publisher
Brzezowski P, Richter A, Grimm B. Regulation and function of tetrapyrrole biosynthesis in plants and algae. Biochim Biophys Acta. 2015;1847:968-85 pubmed publisher
..This article is part of a Special Issue entitled: Chloroplast Biogenesis. ..
Wang P, Liang F, Wittmann D, Siegel A, Shan S, Grimm B. Chloroplast SRP43 acts as a chaperone for glutamyl-tRNA reductase, the rate-limiting enzyme in tetrapyrrole biosynthesis. Proc Natl Acad Sci U S A. 2018;115:E3588-E3596 pubmed publisher
..Our work thus reveals a function of cpSRP43 in Chl biosynthesis and suggests a striking mechanism for posttranslational coordination of LHCP insertion with Chl biosynthesis. ..
Hey D, Grimm B. ONE-HELIX PROTEIN2 (OHP2) Is Required for the Stability of OHP1 and Assembly Factor HCF244 and Is Functionally Linked to PSII Biogenesis. Plant Physiol. 2018;177:1453-1472 pubmed publisher
..We examined the potential functions of the OHP1-OHP2-HCF244 complex in the assembly and/or repair of PSII and propose a role for this heterotrimeric complex in thylakoid membrane biogenesis. ..
Wang P, Grimm B. Comparative Analysis of Light-Harvesting Antennae and State Transition in chlorina and cpSRP Mutants. Plant Physiol. 2016;172:1519-1531 pubmed
Brzezowski P, Sharifi M, Dent R, Morhard M, Niyogi K, Grimm B. Mg chelatase in chlorophyll synthesis and retrograde signaling in Chlamydomonas reinhardtii: CHLI2 cannot substitute for CHLI1. J Exp Bot. 2016;67:3925-38 pubmed publisher
..The results suggest that, unlike in A. thaliana, changes in CHLI2 content observed in the present studies do not affect formation and activity of MgCh in C. reinhardtii. ..
Apitz J, Nishimura K, Schmied J, Wolf A, Hedtke B, van Wijk K, et al
. Posttranslational Control of ALA Synthesis Includes GluTR Degradation by Clp Protease and Stabilization by GluTR-Binding Protein. Plant Physiol. 2016;170:2040-51 pubmed publisher
..It is proposed that the proteolytic activity of Clp protease counteracts GBP binding to assure the appropriate content of GluTR and the adequate ALA synthesis for chlorophyll and heme in higher plants. ..
Hey D, Rothbart M, Herbst J, Wang P, Müller J, Wittmann D, et al
. LIL3, a Light-Harvesting Complex Protein, Links Terpenoid and Tetrapyrrole Biosynthesis in Arabidopsis thaliana. Plant Physiol. 2017;174:1037-1050 pubmed publisher
..We suggest that LIL3 associates with POR and CHLP and thus contributes to the supply of the two metabolites, chlorophyllide and phytyl pyrophosphate, required for the final step in chlorophyll a synthesis. ..