Small players with big roles: microRNAs as targets to inhibit breast cancer progressionStephanie B Greene
Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Curr Drug Targets 11:1059-73. 2010
..Ultimately, miRNAs should provide both important prognostic biomarkers as well as new targetable molecules for the treatment of breast cancer...
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cellsJason I Herschkowitz
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Proc Natl Acad Sci U S A 109:2778-83. 2012
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The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancerStephanie B Greene
Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA
RNA Biol 7:300-4. 2010
..The role that miR-205 plays in directing stem cell fate is still unknown...
BMP signaling in congenital heart disease: new developments and future directionsJun Wang
Institute of Biosciences and Technology, Texas A and M System Health Science Center, 2121 W Holcombe Blvd, Houston, TX 77030, USA
Birth Defects Res A Clin Mol Teratol 91:441-8. 2011
..This review highlights the roles of the bone morphogenetic protein (BMP) signaling pathway in cardiogenesis and how defective BMP signals can disrupt the intricate steps of cardiac formation and cause congenital heart defects...
A putative role for microRNA-205 in mammary epithelial cell progenitorsStephanie B Greene
Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
J Cell Sci 123:606-18. 2010
..Additionally, in normal mouse MECs, high expression of miR-205 was observed in stem-cell-enriched cell populations isolated by FACS using established cell-surface markers...
Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanismJun Wang
Institute of Biosciences and Technology, Texas A and M System Health Science Center, Houston, 77030, USA
Dev Cell 19:903-12. 2010
..Our findings indicate that Bmp signaling directly regulates a miRNA-mediated effector mechanism that downregulates cardiac progenitor genes and enhances myocardial differentiation...