P E Vardas

Summary

Affiliation: University of Crete
Country: Greece

Publications

  1. ncbi request reprint Drug therapy for atrial fibrillation
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, 71000, Voutes, Heraklion, Crete, Greece
    Expert Opin Pharmacother 7:1121-31. 2006
  2. ncbi request reprint Prosthetic aortic valve endocarditis complicated with annular abscess, sub-aortic obstruction and valve dehiscence
    Joannis Hassoulas
    Cardiac Surgery and Heraklion University Hospital Crete, Greece
    Hellenic J Cardiol 50:319-23. 2009
  3. doi request reprint TLR2 and TLR4 gene expression in peripheral monocytes in nondiabetic hypertensive patients: the effect of intensive blood pressure-lowering
    Maria E Marketou
    Cardiology Department, Heraklion University Hospital, Crete
    J Clin Hypertens (Greenwich) 14:330-5. 2012
  4. pmc Asymptomatic papillary fibroelastoma of the aortic valve in a young woman - a case report
    Fragiskos Parthenakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Cardiovasc Ultrasound 7:43. 2009
  5. pmc Risk factors for ischaemic heart disease in a Cretan rural population: a twelve year follow-up study
    Ioannis K Karalis
    Clinic of Social and Family Medicine, School of Medicine, University of Crete, Greece
    BMC Public Health 7:351. 2007
  6. ncbi request reprint Bacterial endocarditis of the mitral valve with dual location
    Fragiskos I Parthenakis
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 47:366-7. 2006
  7. ncbi request reprint Late left ventricular diastolic flow propagation velocity determined by color M-mode Doppler in the assessment of diastolic dysfunction
    Frangiskos I Parthenakis
    Department of Cardiology, Heraklion University Hospital, Stavrakia, Heraklion, Crete, Greece
    J Am Soc Echocardiogr 17:139-45. 2004
  8. ncbi request reprint Amiodarone for the restoration of sinus rhythm in patients with atrial fibrillation
    Panos E Vardas
    Cardiology Department, Heraklion University Hospital, Heraklion, Crete, Greece
    Card Electrophysiol Rev 7:297-9. 2003
  9. ncbi request reprint [European practice guidelines on cardiac pacemakers and cardiac resynchronization therapy. Working Group of the European Society of Cardiology (ESC) on cardiac pacemakers and cardiac resynchronization therapy. Developed in collaboration with the European
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, PO Box 1352, Stavrakia GR 711 10 Heraklion Creta, Grecia
    Rev Esp Cardiol 60:1272.e1-1272.e51. 2007
  10. ncbi request reprint Association of impaired glucose tolerance with increased heart rate and subclinical inflammation
    George F Diakakis
    Cardiology Department, Heraklion University Hospital, Heraklion, Crete, Greece
    Hellenic J Cardiol 46:394-401. 2005

Collaborators

Detail Information

Publications103 found, 100 shown here

  1. ncbi request reprint Drug therapy for atrial fibrillation
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, 71000, Voutes, Heraklion, Crete, Greece
    Expert Opin Pharmacother 7:1121-31. 2006
    ....
  2. ncbi request reprint Prosthetic aortic valve endocarditis complicated with annular abscess, sub-aortic obstruction and valve dehiscence
    Joannis Hassoulas
    Cardiac Surgery and Heraklion University Hospital Crete, Greece
    Hellenic J Cardiol 50:319-23. 2009
    ..An extended workup, including transoesophageal echocardiography, in such a patient with a mechanical valve is mandatory...
  3. doi request reprint TLR2 and TLR4 gene expression in peripheral monocytes in nondiabetic hypertensive patients: the effect of intensive blood pressure-lowering
    Maria E Marketou
    Cardiology Department, Heraklion University Hospital, Crete
    J Clin Hypertens (Greenwich) 14:330-5. 2012
    ..Intensive control of SBP results in attenuation of TLR2 and TLR4 gene expression in those patients. Our findings suggest that a strict SBP target in nondiabetic hypertensive patients may offer additional benefits...
  4. pmc Asymptomatic papillary fibroelastoma of the aortic valve in a young woman - a case report
    Fragiskos Parthenakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Cardiovasc Ultrasound 7:43. 2009
    ..The importance of valve sparing tumour resection even in asymptomatic patients is emphasised...
  5. pmc Risk factors for ischaemic heart disease in a Cretan rural population: a twelve year follow-up study
    Ioannis K Karalis
    Clinic of Social and Family Medicine, School of Medicine, University of Crete, Greece
    BMC Public Health 7:351. 2007
    ..The same population was re-examined twelve years later aiming to describe the trends of CHD risk factors over time and discuss some key points on the natural course of coronary heart disease in a rural population of Crete...
  6. ncbi request reprint Bacterial endocarditis of the mitral valve with dual location
    Fragiskos I Parthenakis
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 47:366-7. 2006
  7. ncbi request reprint Late left ventricular diastolic flow propagation velocity determined by color M-mode Doppler in the assessment of diastolic dysfunction
    Frangiskos I Parthenakis
    Department of Cardiology, Heraklion University Hospital, Stavrakia, Heraklion, Crete, Greece
    J Am Soc Echocardiogr 17:139-45. 2004
    ..Early color M-mode Doppler flow propagation (Ep) through the left ventricle (LV) has been proposed as a useful noninvasive index for assessing LV relaxation, whereas data concerning late velocity propagation (Ap) is lacking...
  8. ncbi request reprint Amiodarone for the restoration of sinus rhythm in patients with atrial fibrillation
    Panos E Vardas
    Cardiology Department, Heraklion University Hospital, Heraklion, Crete, Greece
    Card Electrophysiol Rev 7:297-9. 2003
    ..In conclusion, our findings indicate that amiodarone is an effective and safe antiarrhythmic drug even when administered in large doses. It may be used for the restoration of sinus rhythm when rapid cardioversion is not needed...
  9. ncbi request reprint [European practice guidelines on cardiac pacemakers and cardiac resynchronization therapy. Working Group of the European Society of Cardiology (ESC) on cardiac pacemakers and cardiac resynchronization therapy. Developed in collaboration with the European
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, PO Box 1352, Stavrakia GR 711 10 Heraklion Creta, Grecia
    Rev Esp Cardiol 60:1272.e1-1272.e51. 2007
  10. ncbi request reprint Association of impaired glucose tolerance with increased heart rate and subclinical inflammation
    George F Diakakis
    Cardiology Department, Heraklion University Hospital, Heraklion, Crete, Greece
    Hellenic J Cardiol 46:394-401. 2005
    ..This study was designed to assess possible alterations in heart rate (HR), heart rate variability (HRV) and circulating serum levels of proinflammatory cytokines in patients with impaired glucose tolerance (IGT)...
  11. ncbi request reprint Continuous positive airway pressure therapy lowers vagal tone in patients with obstructive sleep apnoea-hypopnoea syndrome
    Stavros I Chrysostomakis
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    Hellenic J Cardiol 47:13-20. 2006
    ....
  12. ncbi request reprint Pacing follow up techniques and trouble shooting during biventricular pacing
    Panos E Vardas
    Cardiology Department, University Hospital of Heraklion, PO Box 1352, Stavrakia, GR 711 00 Heraklion, Crete, Greece
    J Interv Card Electrophysiol 9:183-7. 2003
    ....
  13. ncbi request reprint Treatment of a large rupture of the external iliac artery by implantation of a coated metal stent
    Michalis I Hamilos
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 46:354-5. 2005
  14. ncbi request reprint Primary prevention of sudden cardiac death: apart from the defibrillator, what is important in patients with myocardial infarction or heart failure?
    Eleftherios M Kallergis
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 48:89-93. 2007
  15. ncbi request reprint Long-term maintenance of normal sinus rhythm in patients with current symptomatic atrial fibrillation: amiodarone vs propafenone, both in low doses
    George E Kochiadakis
    Cardiology Department, University Hospital of Heraklion, Stavrakia, Heraklion, Crete, Greece
    Chest 125:377-83. 2004
    ..To compare the efficacy and safety of amiodarone and propafenone when used for the prevention of atrial fibrillation (AF) and maintenance of normal sinus rhythm in patients with refractory AF...
  16. ncbi request reprint Guidelines for cardiac pacing and cardiac resynchronization therapy. The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, Heraklion, Crete, Greece
    Europace 9:959-98. 2007
  17. ncbi request reprint Acute myocardial infarction in a patient with normal coronary arteries after an allergic reaction
    Mihalis I Hamilos
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 46:79-82. 2005
    ..Acute myocardial infarction following an allergy is an extremely rare clinical entity that, according to existing data, is due to the local release of vasoconstrictive substances as a result of the allergic reaction...
  18. ncbi request reprint Efficacy and safety of oral amiodarone in controlling heart rate in patients with persistent atrial fibrillation who have undergone digitalisation
    George E Kochiadakis
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 46:336-40. 2005
    ..In this study we evaluated the efficacy and safety of oral amiodarone versus placebo for rate control during exercise and daily activities in patients with chronic atrial fibrillation who had undergone digitalisation...
  19. ncbi request reprint Amiodarone as a first-choice drug for restoring sinus rhythm in patients with atrial fibrillation: a randomized, controlled study
    P E Vardas
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Chest 117:1538-45. 2000
    ..To investigate the efficacy and safety of amiodarone administered as the drug of first choice in the conversion of atrial fibrillation, regardless of its duration...
  20. ncbi request reprint Effects of Nebivolol on left ventricular function and exercise capacity in patients with non-ischaemic dilated cardiomyopathy. A randomised placebo-controlled study
    Alexandros P Patrianakos
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Hellenic J Cardiol 46:199-207. 2005
    ..This study assessed the effects of Nebivolol on left ventricular (LV) function and exercise capacity in patients with non-ischaemic dilated cardiomyopathy (NIDC)...
  21. ncbi request reprint Anaemia and heart failure: is its correction a therapeutic target? The role of erythropoietin
    Eleftherios M Kallergis
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 46:222-5. 2005
  22. ncbi request reprint Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, PO Box 1352 Stavrakia, GR 711 10 Heraklion Crete, Greece
    Eur Heart J 28:2256-95. 2007
  23. ncbi request reprint AI-700 (Acusphere)
    Michael I Hamilos
    Cardiology Department, University Hospital, Heraklion, Crete 71001, Greece
    Curr Opin Investig Drugs 6:956-61. 2005
    ..By April 2005, phase III enrollment was expected to be complete by early 2006, and the company expected to file an NDA in the first half of 2006...
  24. doi request reprint CRP in non-dippers: new perspectives and old queries
    Pe Vardas
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    J Hum Hypertens 22:447-9. 2008
  25. ncbi request reprint Geographic differences of pacemaker implant rates in Europe
    Panos E Vardas
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    J Cardiovasc Electrophysiol 13:S23-6. 2002
    ..The aim of this study was to examine the variations in the number of first implants per calendar year in different European countries and to relate the differences to certain socioeconomic indices...
  26. ncbi request reprint Resynchronization therapy: implications for pacemaker implantation in Europe
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    Card Electrophysiol Rev 7:27-9. 2003
    ..Possible education and/or training issues that appear will be addressed respectively, enabling all suitable patients to enjoy the benefits this new therapeutic technique ensures...
  27. ncbi request reprint AAIR versus DDDR pacing in patients with impaired sinus node chronotropy: an echocardiographic and cardiopulmonary study
    P E Vardas
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Pacing Clin Electrophysiol 20:1762-8. 1997
    ..On exertion, the two pacing modes appear to be equally effective, at least in cases where the stimulus-R interval decreases in AAIR mode...
  28. ncbi request reprint Myocardial perfusion in patients with permanent ventricular pacing and normal coronary arteries
    E I Skalidis
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    J Am Coll Cardiol 37:124-9. 2001
    ....
  29. ncbi request reprint Sinus pacemaker function after cardioversion of chronic atrial fibrillation: is sinus node remodeling related with recurrence?
    E G Manios
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    J Cardiovasc Electrophysiol 12:800-6. 2001
    ..The objective of this study was to investigate the temporal changes in sinus node function in postcardioversion chronic atrial fibrillation (AF) patients and their possible relation with the recurrence rates of AF...
  30. pmc Assessment of myocardial adrenergic innervation in patients with sick sinus syndrome: effect of asynchronous ventricular activation from ventricular apical stimulation
    M E Marketou
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Heart 88:255-9. 2002
    ..To investigate ventricular sympathetic innervation in patients with sick sinus syndrome and to detect regional deterioration of adrenergic innervation caused by asynchronous ventricular activation from right ventricular pacing...
  31. ncbi request reprint Spectral analysis of heart rate variability during tilt-table testing in patients with vasovagal syncope
    G E Kochiadakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Int J Cardiol 64:185-94. 1998
    ..The pathological mechanism leading to vasovagal syncope appears to be independent of the specific type of haemodynamic response to tilt testing...
  32. ncbi request reprint Effect of acute atrial fibrillation on phasic coronary blood flow pattern and flow reserve in humans
    G E Kochiadakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Eur Heart J 23:734-41. 2002
    ..To assess the effect of experimentally induced atrial fibrillation on coronary flow in humans...
  33. ncbi request reprint Effects of long-term digoxin therapy on heart rate variability, baroreceptor sensitivity, and exercise capacity in patients with heart failure
    P E Vardas
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Cardiovasc Drugs Ther 12:47-55. 1998
    ....
  34. doi request reprint Arterial stiffness in hypertensives in relation to expression of angiopoietin-1 and 2 genes in peripheral monocytes
    M E Marketou
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    J Hum Hypertens 24:306-11. 2010
    ..This positive correlation may suggest a link between angiogenesis and arterial stiffness in those patients...
  35. ncbi request reprint Pharmacological cardioversion of recent onset atrial fibrillation with intravenous amiodarone in patients receiving long-term amiodarone therapy: is it reasonable?
    Emmanuel M Kanoupakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    J Interv Card Electrophysiol 8:19-26. 2003
    ..Such a combined therapy could be used with a high efficacy and safety for the conversion of recent onset atrial fibrillation in patients who are receiving long-term amiodarone therapy...
  36. ncbi request reprint Electrocardiographic diagnosis of acute myocardial infarction in the presence of ventricular paced rhythm
    G E Kochiadakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Pacing Clin Electrophysiol 24:1289-90. 2001
    ..This report shows that the same sign may also indicate the amount of myocardium in jeopardy and the coronary artery responsible...
  37. ncbi request reprint QT dispersion in patients with mitral valve prolapse is related to the echocardiographic degree of the prolapse and mitral leaflet thickness
    E G Zouridakis
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    Europace 3:292-8. 2001
    ..The echocardiographic assessment of the severity of the prolapse may help to identify a subgroup of patients at increased risk of life-threatening arrhythmias...
  38. ncbi request reprint Sensing issues related to the clinical use of implantable loop recorders
    S I Chrysostomakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Europace 5:143-8. 2003
    ..We also tested whether body position changes influence the sensed electrogram's amplitude, therefore affecting the device's autosensing ability...
  39. ncbi request reprint Electrical storm due to amiodarone induced thyrotoxicosis in a young adult with dilated cardiomyopathy: thyroidectomy as the treatment of choice
    M E Marketou
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Pacing Clin Electrophysiol 24:1827-8. 2001
    ..Medical therapy was ineffective. Thyroidectomy resulted in immediate control of the arrhythmia and permitted reinitiation of amiodarone. At 18-month follow-up, the patient remained euthyroid on amiodarone and ventricular arrhythmia free...
  40. ncbi request reprint Appropriate management of syncope in a patient with hypertrophic cardiomyopathy: rationale behind long-term cardiac rhythm monitoring
    Eva G Arkolaki
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Hellenic J Cardiol 50:144-6. 2009
    ..Accordingly, the device was upgraded to an implantable cardioverter-defibrillator...
  41. ncbi request reprint Electrocardiographic appearance of old myocardial infarction in paced patients
    George E Kochiadakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Pacing Clin Electrophysiol 25:1061-5. 2002
    ....
  42. ncbi request reprint Serum markers of collagen turnover predict future shocks in implantable cardioverter-defibrillator recipients with dilated cardiomyopathy on optimal treatment
    Emmanuel M Kanoupakis
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    J Am Coll Cardiol 55:2753-9. 2010
    ....
  43. doi request reprint Proximal aortic stiffness is related to left ventricular function and exercise capacity in patients with dilated cardiomyopathy
    Alexandros P Patrianakos
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Eur J Echocardiogr 10:425-32. 2009
    ..Patients with heart failure (HF) show abnormal arterial stiffening...
  44. ncbi request reprint The role of laser-induced fluorescence in myocardial tissue characterization: an experimental in vitro study
    G E Kochiadakis
    Cardiology Department, University Hospital of Crete, Heraklion Crete, Greece
    Chest 120:233-9. 2001
    ..This might prove useful in identifying cardiomyopathies and transplant rejection, as well as for myocardial mapping, assisting electrophysiologists in discovering fibrotic arrhythmogenic foci...
  45. ncbi request reprint Effect of angiotensin-converting enzyme inhibitors on systemic inflammation and myocardial sympathetic innervation in normotensive patients with type 2 diabetes mellitus
    M E Marketou
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    J Hum Hypertens 22:191-6. 2008
    ..Our findings indicate the cardioprotective action of ACE-i and suggest that earlier treatment might be appropriate in those patients...
  46. ncbi request reprint Atrial defibrillation threshold in humans minutes after atrial fibrillation induction; "A stitch in time saves nine"
    P E Vardas
    Department of Cardiology, Heraklion University Hospital, P.O. Box 1352, Stavrakia, Heraklion-Crete, Greece
    Eur Heart J 22:1613-7. 2001
    ..Clinical data were not found to affect the defibrillation threshold. CONCLUSIONS: Prolongation of atrial fibrillation over minutes in patients with paroxysmal arrhythmia increases the energy requirements for successful defibrillation...
  47. ncbi request reprint Atrial overdrive pacing for the obstructive sleep apnea-hypopnea syndrome
    Emmanuel N Simantirakis
    Department of Cardiology, Heraklion University Hospital, Heraklion, Crete, Greece
    N Engl J Med 353:2568-77. 2005
    ..We prospectively evaluated the effect of AOP after 24 hours and after one month in patients with the obstructive sleep apnea-hypopnea syndrome and compared it with the use of nasal continuous positive airway pressure (n-CPAP)...
  48. doi request reprint Electrophysiological effects of carvedilol administration in patients with dilated cardiomyopathy
    Emmanuel M Kanoupakis
    Cardiology Department, Heraklion University Hospital, Heraklion, Crete, Greece
    Cardiovasc Drugs Ther 22:169-76. 2008
    ..In this prospective, placebo-controlled trial we examined the electrophysiological effects of a high oral dose of carvedilol in patients with CHF and LVD due to non-ischemic dilated cardiomyopathy...
  49. pmc Alteration of proximal aorta biophysical properties in patients with end stage renal disease
    A P Patrianakos
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    Heart 92:228-32. 2006
    ..To present a novel, non-invasive echocardiographic application to assess the structural and functional properties of the complex composition of the proximal aorta in patients with end stage renal disease (ESRD)...
  50. ncbi request reprint Implantable loop recorder undersensing mimicking complete heart block
    S I Chrysostomakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Europace 4:211-3. 2002
    ..Increased attention should be given by the interpreter of the device's recordings to avoid false positive diagnoses that might lead to serious therapeutic actions...
  51. ncbi request reprint Effects of amiodarone and diltiazem on persistent atrial fibrillation conversion and recurrence rates: a randomized controlled study
    Emmanuel G Manios
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    Cardiovasc Drugs Ther 17:31-9. 2003
    ..To assess the effects of amiodarone and diltiazem on atrial fibrillation (AF) induced atrial electrical remodeling and their clinical implications...
  52. ncbi request reprint Left ventricular mechanics during right ventricular apical or left ventricular-based pacing in patients with chronic atrial fibrillation after atrioventricular junction ablation
    Emmanuel N Simantirakis
    Cardiology Department, Heraklion University Hospital, PO Box 1352 Stavrakia, Heraklion, Crete, Greece
    J Am Coll Cardiol 43:1013-8. 2004
    ....
  53. ncbi request reprint Comparative efficacy of nebivolol versus carvedilol on left ventricular function and exercise capacity in patients with nonischemic dilated cardiomyopathy. A 12-month study
    Alexandros P Patrianakos
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Am Heart J 150:985. 2005
    ..To compare the efficacy of nebivolol versus carvedilol on left ventricular (LV) function and exercise capacity in patients with nonischemic dilated cardiomyopathy (NIDC)...
  54. ncbi request reprint Regional coronary flow and contractile reserve in patients with idiopathic dilated cardiomyopathy
    Emmanuel I Skalidis
    Cardiology Department, University Hospital of Heraklion, Heraklion, Greece
    J Am Coll Cardiol 44:2027-32. 2004
    ..The purpose of this study was to assess regional coronary flow and contractile reserve in patients with idiopathic dilated cardiomyopathy (IDCM)...
  55. ncbi request reprint Restrictive filling pattern is associated with increased humoral activation and impaired exercise capacity in dilated cardiomyopathy
    Alexander P Patrianakos
    Cardiology Department, University Hospital of Heraklion, P O Box 1352 Stavrakia, Heraklion Crete, Greece
    Eur J Heart Fail 6:735-43. 2004
    ....
  56. ncbi request reprint Acute electrophysiologic effects of inhaled salbutamol in humans
    Eleftherios M Kallergis
    Department of Cardiology, University Hospital of Heraklion, 71000, Voutes, Heraklion Crete, Greece
    Chest 127:2057-63. 2005
    ..The purpose of this study was to evaluate the cardiac electrophysiologic effects of a single, regular dose of an inhaled beta2-agonist in humans...
  57. ncbi request reprint Relation of cardiac sympathetic innervation to proinflammatory cytokine levels in patients with heart failure secondary to idiopathic dilated cardiomyopathy
    Fragiskos I Parthenakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Am J Cardiol 91:1190-4. 2003
    ....
  58. ncbi request reprint Differential expression of vascular smooth muscle-modulating microRNAs in human peripheral blood mononuclear cells: novel targets in essential hypertension
    J E Kontaraki
    Molecular Cardiology Laboratory, School of Medicine, University of Crete, Heraklion, Greece
    J Hum Hypertens 28:510-6. 2014
    ..Our data provide important evidence that VSMC-modulating microRNAs are closely related to essential hypertension in humans and they may represent potential therapeutic targets in essential hypertension. ..
  59. ncbi request reprint Myocardin gene regulatory variants as surrogate markers of cardiac hypertrophy - study in a genetically homogeneous population
    J E Kontaraki
    Molecular Cardiology Laboratory, Division of Internal Medicine, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Clin Genet 73:71-8. 2008
    ..Our data suggest that functional natural myocardin promoter variation might be a genetic factor contributing to inter-individual differences in the development of cardiac hypertrophy...
  60. ncbi request reprint Autonomic imbalance during the day in patients with inflammatory bowel disease in remission. Evidence from spectral analysis of heart rate variability over 24 hours
    I A Mouzas
    Gastroenterology Department, University Hospital of Heraklion, Medical School, University of Crete, Greece
    Dig Liver Dis 34:775-80. 2002
    ..Autonomic function in inflammatory bowel disease has not yet been studied by means of analysis of 24-hour heart rate variability...
  61. ncbi request reprint The role of the post-cardioversion time course of hs-CRP levels in clarifying the relationship between inflammation and persistence of atrial fibrillation
    E M Kallergis
    Department of Cardiology, Heraklion University Hospital, 71100, Voutes, Heraklion, Crete, Greece
    Heart 94:200-4. 2008
    ..Although recent studies suggest that inflammation is involved in the pathogenesis of atrial fibrillation (AF), it remains controversial whether it is a consequence or a cause of the arrhythmia...
  62. doi request reprint Ivabradine improves coronary flow reserve in patients with stable coronary artery disease
    Emmanouil I Skalidis
    Cardiology Department, University Hospital of Heraklion, and Biostatistics Lab, University of Crete, Crete, Greece
    Atherosclerosis 215:160-5. 2011
    ..The purpose of this study was to assess the effects of ivabradine on coronary flow velocity and flow reserve (CFR) in patients with stable coronary artery disease (CAD)...
  63. doi request reprint Early cardiac gene transcript levels in peripheral blood mononuclear cells in patients with untreated essential hypertension
    Joanna E Kontaraki
    Molecular Cardiology Laboratory, School of Medicine, University of Crete, and Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    J Hypertens 29:791-7. 2011
    ....
  64. ncbi request reprint Altered expression of early cardiac marker genes in circulating cells of patients with hypertrophic cardiomyopathy
    Joanna E Kontaraki
    Department of Cardiology, University Hospital of Heraklion, PO Box 1352, Stavrakia, Heraklion, Crete, Greece
    Cardiovasc Pathol 16:329-35. 2007
    ..In this study, we investigated whether the expression of early cardiac genes is altered in the peripheral blood of patients with hypertrophic cardiomyopathy...
  65. ncbi request reprint Acute effect of esmolol intravenously on coronary microcirculation in patients with idiopathic dilated cardiomyopathy
    Emmanuel I Skalidis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Am J Cardiol 100:1299-302. 2007
    ..These alterations in microvascular function, which are partially reversed by beta blockade, may be 1 of the underlying mechanisms that contribute to the improved prognosis of patients with IDC under such therapy...
  66. doi request reprint Effect of sinus rhythm restoration after electrical cardioversion on apelin and brain natriuretic Peptide prohormone levels in patients with persistent atrial fibrillation
    Eleftherios M Kallergis
    Department of Cardiology, University Hospital of Heraklion, Heraklion, Crete, Greece
    Am J Cardiol 105:90-4. 2010
    ..This could influence systemic hemodynamics and pharmacologic measures designed to treat this arrhythmia...
  67. doi request reprint Predicting future shocks in implantable cardioverter defibrillator recipients: the role of biomarkers
    Emmanuel M Kanoupakis
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    Europace 11:1434-9. 2009
    ..Biomarkers, which are playing a growing role in the prognosis and treatment of patients with heart failure, could provide an auxiliary tool in this context, given that their measurement is now easy and widely available...
  68. ncbi request reprint Myocardial gene expression alterations in peripheral blood mononuclear cells of patients with idiopathic dilated cardiomyopathy
    Joanna E Kontaraki
    Molecular Cardiology Laboratory, School of Medicine, University of Crete, Crete, Greece
    Eur J Heart Fail 12:541-8. 2010
    ..To assess cardiac gene expression in peripheral blood cells of patients with idiopathic dilated cardiomyopathy (IDCM) and its relationship to echocardiographic left ventricular (LV) function...
  69. ncbi request reprint A comparative study of the efficacy and safety of procainamide versus propafenone versus amiodarone for the conversion of recent-onset atrial fibrillation
    George E Kochiadakis
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Am J Cardiol 99:1721-5. 2007
    ..In conclusion, all 3 medications, when administered intravenously, are effective in the restoration of sinus rhythm in recent-onset AF. Amiodarone and propafenone are more effective whereas procainamide and propafenone are faster...
  70. ncbi request reprint Amino-terminal pro-brain natriuretic peptide predicts ventricular arrhythmogenesis in patients with ischemic cardiomyopathy and implantable cardioverter-defibrillators
    Emmanuel G Manios
    Department of Cardiology, University Hospital of Heraklion, 71000, Voutes, Heraklion Crete, Greece
    Chest 128:2604-10. 2005
    ....
  71. ncbi request reprint Relation of proximal aorta stiffness to left ventricular diastolic function in patients with end-stage renal disease
    Alexandros P Patrianakos
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    J Am Soc Echocardiogr 20:314-23. 2007
    ..We examined the relationship between proximal aortic stiffness and left ventricular (LV) diastolic function in patients with end-stage renal disease (ESRD)...
  72. ncbi request reprint Value of Doppler index combining systolic and diastolic myocardial performance in predicting cardiopulmonary exercise capacity in patients with congestive heart failure: effects of dobutamine
    Fragiskos I Parthenakis
    Cardiology Department, Heraklion University Hospital, Stavrakia, Crete, Greece
    Chest 121:1935-41. 2002
    ..MPI also was correlated with other conventional echocardiographic indexes of left ventricular (LV) function, and its ability to assess cardiopulmonary exercise capacity in those patients was investigated...
  73. ncbi request reprint Atrial fibrillation is associated with increased neurohumoral activation and reduced exercise tolerance in patients with non-ischemic dilated cardiomyopathy
    Frangiskos I Parthenakis
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    Int J Cardiol 118:206-14. 2007
    ..To assess atrial fibrillation (AF) associated differences in proinflammatory cytokines, natriuretic peptide levels and exercise capacity in patients with heart failure (HF) secondary to non-ischemic dilated cardiomyopathy (NIDC)...
  74. ncbi request reprint Clarithromycin treatment and QT prolongation in childhood
    Ioannis Germanakis
    Department of Paediatrics, University of Crete, Heraklion, Greece
    Acta Paediatr 95:1694-6. 2006
    ..A modest (average 22 ms, 95% CI 14-30 ms) but significant QTc prolongation (p<0.001) was observed, with seven cases having a QTc >440 ms during treatment (including a single case with QTc >460 ms)...
  75. ncbi request reprint Left ventricular mechanics and myocardial blood flow following restoration of normal activation sequence in paced patients with long-term right ventricular apical stimulation
    Emmanuel N Simantirakis
    Cardiology Department, Heraklion University Hospital, Crete, Greece
    Chest 124:233-41. 2003
    ..However, it is not clear whether the long-term disturbances it causes are reversible after the restoration of the normal ventricular activation sequence...
  76. ncbi request reprint Comparative effects of carvedilol and amiodarone on conversion and recurrence rates of persistent atrial fibrillation
    Emmanuel M Kanoupakis
    Department of Cardiology, Heraklion University Hospital, Heraklion, Greece
    Am J Cardiol 94:659-62. 2004
    ..Although the 2 drugs had similar effects on cardioversion rates, amiodarone was superior in terms of sinus rhythm maintenance after conversion...
  77. ncbi request reprint Severe bradyarrhythmias in patients with sleep apnoea: the effect of continuous positive airway pressure treatment: a long-term evaluation using an insertable loop recorder
    Emmanuel N Simantirakis
    Department of Cardiology, Heraklion University Hospital, Box 1352, Stavrakia Crete, 711 10 Heraklion, Crete, Greece
    Eur Heart J 25:1070-6. 2004
    ....
  78. ncbi request reprint Ventricular special defect in the elderly: an uncommon clinical entity
    Alexander P Patrianakos
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Hellenic J Cardiol 46:158-60. 2005
    ..Here we describe an 86-year-old patient, totally asymptomatic, with a muscular type of VSD that showed interesting, canal-like echocardiographic images...
  79. ncbi request reprint Effects of successful cardioversion of persistent atrial fibrillation on right ventricular refractoriness and repolarization
    Emmanuel G Manios
    Department of Cardiology, University Hospital of Heraklion, P O Box 1352 Stavrakia Voutes, 7100 Heraklion, Crete, Greece
    Europace 7:34-9. 2005
    ..Changes in ventricular refractoriness and repolarization after successful electrical cardioversion to sinus rhythm in persistent atrial fibrillation (AF) patients were studied...
  80. ncbi request reprint Myocardial perfusion and adrenergic innervation in patients with RBBB and LAfB: the effect of altering the activation sequence with right ventricular apical pacing
    Emmanuel N Simantirakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Pacing Clin Electrophysiol 26:1202-7. 2003
    ..To a smaller degree these patients reveal myocardial perfusion disturbances in which pacing has a limited medium-term effect...
  81. ncbi request reprint Endothelial cell function during atrial fibrillation and after restoration of sinus rhythm
    Emmanuel I Skalidis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    Am J Cardiol 99:1258-62. 2007
    ..1 +/- 3.9% vs 17.2 +/- 4.0% vs 16.9 +/- 4.1%). In conclusion, AF is associated with impairment in endothelial function that improves after sinus rhythm restoration...
  82. ncbi request reprint Early effects of simvastatin versus atorvastatin on oxidative stress and proinflammatory cytokines in hyperlipidemic subjects
    Mary E Marketou
    Department of Cardiology, Heraklion University Hospital, Heraklion, Crete, Greece
    Angiology 57:211-8. 2006
    ..These effects became significant 2 hours following the initiation of therapy...
  83. doi request reprint Central aortic stiffness in patients with nonischemic dilated cardiomyopathy: relationship with neurohumoral activation
    Alexandros P Patrianakos
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    J Card Fail 15:665-72. 2009
    ..The aim of the present study was to examine the association between aortic stiffness and neurohumoral activation in patients with nonischemic dilated cardiomyopathy (NIDC)...
  84. ncbi request reprint Plasma Levels of Nitrites/Nitrates in Patients with Chronic Atrial Fibrillation are Increased after Electrical Restoration of Sinus Rhythm
    Dragana Nikitovic
    Department of Clinical Chemistry Biochemistry, Heraklion University Hospital, Crete, Greece
    J Interv Card Electrophysiol 7:171-6. 2002
    ..The aim of this work was to assess endothelial function in AF patients before and at various time points after cardioversion...
  85. ncbi request reprint Correlation of plasma N-terminal pro-brain natriuretic peptide levels with left ventricle mass in children treated with anthracyclines
    Ioannis Germanakis
    Department of Pediatrics, Division of Pediatric Cardiology, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece
    Int J Cardiol 108:212-5. 2006
    ....
  86. ncbi request reprint Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation
    George E Kochiadakis
    Cardiology Department, University Hospital of Heraklion, Heraklion, Crete, Greece
    Am J Cardiol 94:1563-6. 2004
    ..For the long-term maintenance of normal sinus rhythm, propafenone seems to be more effective than sotalol...
  87. doi request reprint CRT and exercise capacity in heart failure: the impact of mitral valve regurgitation
    Frangiskos I Parthenakis
    Cardiology Department, Heraklion University Hospital, PO Box 1352, Heraklion, Crete, Greece
    Europace 10:iii96-100. 2008
    ..Therefore, this review will focus on the effect of CRT on the haemodynamic role of functional MR and its impact on exercise performance in patients with chronic HF...
  88. doi request reprint Extracellular matrix alterations in patients with paroxysmal and persistent atrial fibrillation: biochemical assessment of collagen type-I turnover
    Eleftherios M Kallergis
    Department of Cardiology, University Hospital of Heraklion, Crete, Greece
    J Am Coll Cardiol 52:211-5. 2008
    ..We investigated whether the serum markers of collagen turnover differed in various forms of atrial fibrillation (AF) and in sinus rhythm (SR) in humans...
  89. doi request reprint NT-proBNP response to dobutamine stress echocardiography predicts left ventricular contractile reserve in dilated cardiomyopathy
    Frangiskos I Parthenakis
    Department of Cardiology, Heraklion University Hospital, Crete, Greece
    Eur J Heart Fail 10:475-81. 2008
    ..Brain natriuretic peptide (BNP) and left ventricular (LV) inotropic reserve are major prognostic indexes in heart failure (HF)...
  90. doi request reprint Biventricular pacing in paced patients with normal hearts
    Emmanuel N Simantirakis
    Department of Cardiology, Heraklion University Hospital, Heraklion, Crete, Greece
    Europace 11:v77-81. 2009
    ....
  91. ncbi request reprint Segmental pattern of myocardial sympathetic denervation in idiopathic dilated cardiomyopathy: relationship to regional wall motion and myocardial perfusion abnormalities
    F I Parthenakis
    Cardiology Department, University Hospital of Heraklion, Crete, Greece
    J Nucl Cardiol 9:15-22. 2002
    ..Cardiac MIBG uptake is diminished in patients with heart failure. However, it is not known how this reduction is related to regional abnormalities of myocardial wall motion or perfusion...
  92. ncbi request reprint Cardiac resynchronization and myocardial oxidative metabolism
    Emmanuel I Skalidis
    Circulation 107:e220; author reply e220. 2003
  93. ncbi request reprint Phasic coronary blood flow velocity pattern and flow reserve in the atrium: regulation of left atrial myocardial perfusion
    Emmanuel I Skalidis
    Cardiology Department, University Hospital of Heraklion, 71110 Heraklion, Crete, Greece
    J Am Coll Cardiol 41:674-80. 2003
    ..The purpose of this study was to assess rest and stress atrial coronary blood flow (CBF) velocity and flow reserve...
  94. ncbi request reprint Altered proximal aortic stiffness and endothelin plasma levels in diabetic patients with end-stage renal disease
    Dimitrios Karakitsos
    Department of Nephrology, University Hospital of Heraklion, Crete, Greece
    ASAIO J 53:343-50. 2007
    ..Diabetic patients with ESRD had significantly increased proximal aortic stiffness and significantly altered plasma levels of endothelin as compared with the nondiabetic...
  95. ncbi request reprint Association of serum total homocysteine with the extent of ischemic heart disease in a Mediterranean cohort
    George Vrentzos
    Department of Internal Medicine, University Hospital of Crete, Greece
    Angiology 55:517-24. 2004
    ..27; p < 0.01; n = 67). In this study, the serum concentrations of tHcy correlated with the extent of coronary atherosclerosis, independently of other classical risk factors, with the exception of diabetes mellitus...
  96. ncbi request reprint Does the arrhythmic risk of patients with ischaemic cardiomyopathy really benefit from revascularisation therapy?
    Eleftherios M Kallergis
    Hellenic J Cardiol 49:203-6. 2008
  97. doi request reprint Prognosis, disease progression, and treatment of atrial fibrillation patients during 1 year: follow-up of the Euro Heart Survey on atrial fibrillation
    Robby Nieuwlaat
    Department of Cardiology, University Hospital Maastricht, Maastricht, The Netherlands
    Eur Heart J 29:1181-9. 2008
    ..To gain insight in the prognosis and treatment of atrial fibrillation (AF) patients during 1-year follow-up in the Euro Heart Survey (EHS) on AF...
  98. ncbi request reprint [Guidelines in cardiac pacing and resynchronization therapy]
    Panos E Vardas
    Kardiol Pol 65:1449-87; discussion 1488-9. 2007
  99. ncbi request reprint European Society of Cardiology guidelines and health systems affordability in Europe: the scientific, economic & political component
    Panos E Vardas
    Hellenic J Cardiol 48:389. 2007
  100. ncbi request reprint Achievement of pulmonary vein isolation in patients undergoing circumferential pulmonary vein ablation: a randomized comparison between two different isolation approaches
    Xingpeng Liu
    Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing, China
    J Cardiovasc Electrophysiol 17:1263-70. 2006
    ..We investigated whether the clinical outcome depends on the PV isolation approach used during the first-time CPVA procedure...
  101. ncbi request reprint Gender-related differences in presentation, treatment, and outcome of patients with atrial fibrillation in Europe: a report from the Euro Heart Survey on Atrial Fibrillation
    Nikolaos Dagres
    University of Athens, Second Cardiology Department, Attikon University Hospital, Athens, Greece
    J Am Coll Cardiol 49:572-7. 2007
    ..This study sought to investigate gender-related differences in patients with atrial fibrillation (AF) in Europe...