Eleftherios Vairaktaris

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint Plasminogen activator inhibitor-1 polymorphism is associated with increased risk for oral cancer
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Oral Oncol 42:888-92. 2006
  2. ncbi request reprint Effect of thrombosis-related gene polymorphisms upon oral cancer: a regression analysis
    Antonis Vylliotis
    D D S, Ph D, Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, Athens 12461, Greece
    Anticancer Res 33:4033-9. 2013
  3. ncbi request reprint Diabetes enhances the expression of H-ras and suppresses the expression of EGFR leading to increased cell proliferation
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Histol Histopathol 24:531-9. 2009
  4. ncbi request reprint The hamster model of sequential oral oncogenesis
    E Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Kifissias and Perikleous Stavrou 9, Athens 11521, Greece
    Oral Oncol 44:315-24. 2008
  5. ncbi request reprint Increased risk of oral cancer in diabetic animals is not associated with c-jun activation pathway
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Athens, Greece
    J Craniomaxillofac Surg 35:382-7. 2007
  6. ncbi request reprint A metalloproteinase-13 polymorphism affecting its gene expression is associated with advanced stages of oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, GR 12462, Greece
    Anticancer Res 27:4027-30. 2007
  7. ncbi request reprint EGFR and c-Jun exhibit the same pattern of expression and increase gradually during the progress of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    In Vivo 21:791-6. 2007
  8. ncbi request reprint Expression of cell cycle regulator p16 is not affected by diabetes during oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    In Vivo 21:745-50. 2007
  9. ncbi request reprint Increased risk for oral cancer is associated with coagulation factor XIII but not with factor XII
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    Oncol Rep 18:1537-43. 2007
  10. ncbi request reprint Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with increased risk for oral cancer
    Eleftherios Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Acta Oncol 46:1097-102. 2007

Collaborators

Detail Information

Publications71

  1. ncbi request reprint Plasminogen activator inhibitor-1 polymorphism is associated with increased risk for oral cancer
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Oral Oncol 42:888-92. 2006
    ..Possibly, increased PAI-1 promotes initial development of oral cancer through regulation of cell detachment and delays further tumor progression by inhibiting vascularization...
  2. ncbi request reprint Effect of thrombosis-related gene polymorphisms upon oral cancer: a regression analysis
    Antonis Vylliotis
    D D S, Ph D, Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, Athens 12461, Greece
    Anticancer Res 33:4033-9. 2013
    ..Comparing the present findings with previous knowledge, possible interactions of these factors and their relation to the risk for OSCC development are discussed. ..
  3. ncbi request reprint Diabetes enhances the expression of H-ras and suppresses the expression of EGFR leading to increased cell proliferation
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Histol Histopathol 24:531-9. 2009
    ....
  4. ncbi request reprint The hamster model of sequential oral oncogenesis
    E Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Kifissias and Perikleous Stavrou 9, Athens 11521, Greece
    Oral Oncol 44:315-24. 2008
    ....
  5. ncbi request reprint Increased risk of oral cancer in diabetic animals is not associated with c-jun activation pathway
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Athens, Greece
    J Craniomaxillofac Surg 35:382-7. 2007
    ..The expression of oncogenic protein c-jun was investigated in an experimental model of chemically induced carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats...
  6. ncbi request reprint A metalloproteinase-13 polymorphism affecting its gene expression is associated with advanced stages of oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, GR 12462, Greece
    Anticancer Res 27:4027-30. 2007
    ....
  7. ncbi request reprint EGFR and c-Jun exhibit the same pattern of expression and increase gradually during the progress of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    In Vivo 21:791-6. 2007
    ..In order to investigate their possible correlation with sequential histological stages of OSCC formation, we established an experimental model of induced oral carcinogenesis in Syrian golden hamsters...
  8. ncbi request reprint Expression of cell cycle regulator p16 is not affected by diabetes during oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    In Vivo 21:745-50. 2007
    ..The expression of p16 was investigated in an experimental model of chemically induced carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats...
  9. ncbi request reprint Increased risk for oral cancer is associated with coagulation factor XIII but not with factor XII
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    Oncol Rep 18:1537-43. 2007
    ..Nevertheless, this thinner and less porous fibrin network inhibits cell migration...
  10. ncbi request reprint Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with increased risk for oral cancer
    Eleftherios Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Acta Oncol 46:1097-102. 2007
    ..In light to recently found contribution of factors associated with thrombosis and inflammation to carcinogenesis, we investigated the possible association of angiotensin I- converting enzyme (ACE) with increased risk for oral cancer...
  11. ncbi request reprint Diabetes enhances cell proliferation but not Bax/Bcl-2-mediated apoptosis during oral oncogenesis
    E Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Int J Oral Maxillofac Surg 37:60-5. 2008
    ..These data suggest that diabetes results in increased cell proliferation during oral oncogenesis, but this is accomplished without affecting the Bax/Bcl-2-mediated apoptotic pathways...
  12. ncbi request reprint Diabetes does not influence oral oncogenesis through fibroblast growth factor receptors
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    In Vivo 21:623-8. 2007
    ..The expression of FGFR-2 and FGFR-3 investigated in an experimental model of chemically induced carcinogenesis in normal and diabetic (type I) rats...
  13. ncbi request reprint Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University ofAthens Medical School, Athens, Greece
    In Vivo 21:615-21. 2007
    ..The expression of N-ras and ets-1 proteins was investigated in an experimental model of chemically-induced carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats...
  14. ncbi request reprint The interleukin-1 beta gene polymorphism +3953 C/T is not associated with risk for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 27:3981-6. 2007
    ..Considering the demonstrated effect of other interleukins to the development of oral cancer, this study investigated whether the +3953 C/Tpolymorphism in the IL-1beta gene is associated with this malignancy...
  15. ncbi request reprint The interleukin-18 -607A/C polymorphism is not associated with risk for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, GR 12462, Greece
    Anticancer Res 27:4011-4. 2007
    ..The purpose of the present study was to investigate the association of angiogenesis-inhibitor interleukin-18 (IL-18) with risk for oral cancer, with regard to the recently found contribution of cytokines to carcinogenesis...
  16. doi request reprint Orbital cellulitis, orbital subperiosteal and intraorbital abscess: report of three cases and review of the literature
    Eleftherios Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    J Craniomaxillofac Surg 37:132-6. 2009
    ..Without appropriate treatment orbital infection may lead to serious complications, even death...
  17. ncbi request reprint H-ras and c-fos exhibit similar expression patterns during most stages of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    In Vivo 22:621-8. 2008
    ..The present study used an animal model for the simultaneous investigation of H-Ras and c-Fos expression in sequential stages of oral oncogenesis...
  18. ncbi request reprint Angiotensinogen polymorphism is associated with risk for malignancy but not for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Anticancer Res 28:1675-9. 2008
    ..In light of the recently found contribution of angiogenic and inflammation-related factors to malignancies, this study investigated the possible association of the angiotensinogen gene (AGT) with increased risk of oral cancer...
  19. doi request reprint Delayed appearance of diplopia due to orbital emphysema after repair of orbital fractures
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:e8-e10. 2008
    ..Under local anesthesia, aspiration-decompression was performed using a 25-gauge needle. On the next day, the patient was free of pain, and 2 days after surgery the diplopia and exophthalmos resolved with no sequelae...
  20. ncbi request reprint The interleukin-10 (-1082A/G) polymorphism is strongly associated with increased risk for oral squamous cell carcinoma
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, GR 12462 Athens, Greece
    Anticancer Res 28:309-14. 2008
    ..Based on this, the -1082A/G polymorphism, which influences IL-10 gene expression level, was investigated in regard to its possible association with risk for oral cancer...
  21. ncbi request reprint A DNA polymorphism of stromal-derived factor-1 is associated with advanced stages of oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Anticancer Res 28:271-5. 2008
    ....
  22. doi request reprint Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma
    Eleftherios Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, 12462, Athens, Greece
    J Cancer Res Clin Oncol 134:821-32. 2008
    ..The present retrospective case-control study examines possible interactions between seven cytokine genotype polymorphisms and their combinatory effect in predicting the occurrence of OSCC in Caucasians...
  23. ncbi request reprint Diabetes and oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Kifissias and Perikleous Stavrou 9, Athens 11524, Greece
    Anticancer Res 27:4185-93. 2007
    ....
  24. ncbi request reprint The platelet glycoprotein Ibalpha VNTR polymorphism is associated with risk for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, GR 12462, Greece
    Anticancer Res 27:4121-5. 2007
    ..The purpose of this study was to investigate the possible relation of another platelet glycoprotein, Iba (GPIbalpha), with oral oncogenesis...
  25. ncbi request reprint Association of -1171 promoter polymorphism of matrix metalloproteinase-3 with increased risk for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 27:4095-100. 2007
    ..The present study investigated the possible association of -1171 5A/6A polymorphism, which influences expression of MMP-3, with risk for oral cancer...
  26. ncbi request reprint Enhancement of erbB2 and erbB3 expression during oral oncogenesis in diabetic rats
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    J Cancer Res Clin Oncol 134:337-44. 2008
    ..The expression of erbB2 and erbB3 receptors was investigated in an experimental model of chemically induced oral carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats...
  27. ncbi request reprint Abundance and localization of skeletal muscle-related erbB2 may stimulate tumour growth during initial stages of oral oncogenesis
    E Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    J Musculoskelet Neuronal Interact 7:185-90. 2007
    ..On the contrary, erbB3 was not expressed at all either in normal or tumour tissue...
  28. ncbi request reprint Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans
    Eleftherios Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, 11521 Athens, Greece
    Oncol Rep 17:963-8. 2007
    ..These results indicate that this polymorphism could serve as a genetic marker for the susceptibility of cancer in the oral cavity...
  29. ncbi request reprint Strong association of interleukin-4 (-590 C/T) polymorphism with increased risk for oral squamous cell carcinoma in Europeans
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:796-802. 2007
    ..The present study was performed to investigate the possible association of -590 C/T polymorphism in the interleukin-4 (IL-4) gene which affects its expression with the risk for development of oral cancer...
  30. ncbi request reprint Strong association of interleukin-6 -174 G>C promoter polymorphism with increased risk of oral cancer
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    Int J Biol Markers 21:246-50. 2006
    ..001; Fisher's exact test). These findings suggest that the -174 G>C polymorphism, by affecting IL-6 gene expression, is strongly associated with oral oncogenesis...
  31. ncbi request reprint Association of matrix metalloproteinase-1 (-1607 1G/2G) polymorphism with increased risk for oral squamous cell carcinoma
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 27:459-64. 2007
    ....
  32. doi request reprint Gene polymorphisms related to angiogenesis, inflammation and thrombosis that influence risk for oral cancer
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Athens, Greece
    Oral Oncol 45:247-53. 2009
    ..Based on these findings and previous reports, possible interactions of the implicated factors leading to OSCC development, as well as an algorithm of risk estimation are discussed...
  33. ncbi request reprint Loss of tumour suppressor p16 expression in initial stages of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 27:979-84. 2007
    ..p16 expression in sequential histological stages of oral squamous cell carcinoma (OSCC) formation was investigated using an experimental model of induced oral carcinogenesis in Syrian golden hamsters...
  34. ncbi request reprint A metalloproteinase-9 polymorphism which affects its expression is associated with increased risk for oral squamous cell carcinoma
    E Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, Athens, GR 12462, Greece
    Eur J Surg Oncol 34:450-5. 2008
    ..In light to recently found contribution of factors associated with angiogenesis, thrombosis and inflammation to carcinogenesis, we investigated the possible association of metalloproteinase-9 (MMP-9) with increased risk of oral cancer...
  35. ncbi request reprint FGFR-2 and -3 play an important role in initial stages of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 26:4217-21. 2006
    ..This study was designed to determine gradual FGFR-2 and FGFR-3 expression in sequential stages of oral carcinogenesis in an experimental animal system of Syrian golden hamsters...
  36. ncbi request reprint Diabetes alters expression of p53 and c-myc in different stages of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Mikras Asias 75, Athens 115 27, Greece
    Anticancer Res 27:1465-73. 2007
    ..The expression of tumour suppressor p53 and oncogene c-myc was investigated in an experimental model of chemically induced carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats...
  37. ncbi request reprint Coagulation-related factors, thrombomodulin and protein Z, are not associated with risk for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 27:2449-51. 2007
    ..The link between thrombosis and cancer has been well established. Levels of protein Z and thrombomodulin indirectly regulate thrombin productionl and therefore may affect cancer susceptibility...
  38. ncbi request reprint The 1040C/T polymorphism influencing thermal stability and activity of thrombin activatable fibrinolysis inhibitor is associated with risk for oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Am J Hematol 82:1010-2. 2007
    ..I. 0.13-1.14), while no significant difference was observed in C/T heterozygotes. The observed prophylactic effect of increased TAFI activity might result from reduction of plasmin and inhibition of extracellular matrix dissolution...
  39. ncbi request reprint Association of polymorphisms in Tumor Necrosis Factor Alpha and Beta genes with increased risk for oral cancer
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Eginition Hospital, Athens 11522, Greece
    Anticancer Res 29:2379-86. 2009
    ..In light of the recently found contribution of inflammation-related factors to oral oncogenesis, the possible correlation of tumor necrosis factor alpha and beta genes (TNF-alpha and TNF-beta) with risk of oral cancer was investigated...
  40. doi request reprint Association of leptin -2548G/A and leptin receptor Q223R polymorphisms with increased risk for oral cancer
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Kifissias and Perikleous Stavrou 9, 11524, Athens, Greece
    J Cancer Res Clin Oncol 135:603-12. 2009
    ....
  41. ncbi request reprint High gene expression of matrix metalloproteinase-7 is associated with early stages of oral cancer
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Athens, Greece
    Anticancer Res 27:2493-8. 2007
    ..In the light of the recently found contribution of matrix metalloproteinases (MMPs) to oral oncogenesis, the correlation of MMP-7 with risk for oral cancer was investigated...
  42. ncbi request reprint Expression of ets-1 is not affected by N-ras or H-ras during oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    J Cancer Res Clin Oncol 133:227-33. 2007
    ..To determine whether ras-activated cascades lead to activation of ets-1 expression in sequential histological stages of oral oncogenesis in an experimental animal model...
  43. ncbi request reprint The co-expression of c-myc and p53 increases and reaches a plateau early in oral oncogenesis
    Veronica Papakosta
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Mikras Asias 75, Athens 115 27, Greece
    Anticancer Res 26:2957-62. 2006
    ..The expressions of the p53 and c-myc genes, both strongly related to cell proliferation and apoptosis, were studied in sequential histological grades of oral carcinogenesis in an animal model...
  44. doi request reprint Prevalence of human papillomavirus in saliva and cervix of sexually active women
    Maria Adamopoulou
    Department of Maxillofacial Surgery, Attikon University Hospital, Athens, Greece
    Gynecol Oncol 129:395-400. 2013
    ..However, the relation between oral and cervical HPV infection is not fully understood. This study evaluates the prevalence rate and type-concordance of HPVs in these areas...
  45. ncbi request reprint Metastases following biopsy of oral carcinoma in hamsters and the role of local prebiopsy bleomycin
    George Rallis
    Department of Oral and Maxillofacial Surgery, General Hospital of Athens KAT, Kifissia, Athens, Greece
    Anticancer Res 28:2253-7. 2008
    ..This animal study researches the effect of biopsy on metastasis of oral carcinoma...
  46. ncbi request reprint A common 9 bp deletion in the ataxia-telangiectasia-mutated gene is not associated with oral cancer
    Sofia Spyridonidou
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens 11521, Greece
    Anticancer Res 29:3191-3. 2009
    ..Given the fact that the loss of heterozygosity at the ATM locus is common in head and neck tumours, we investigated the possible association of 7636del9, which is the most frequent ATM deletion, with risk for oral cancer...
  47. doi request reprint Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with decreased risk for basal cell carcinoma
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, 12461 Athens, Greece
    Arch Dermatol Res 305:333-9. 2013
    ..The protective effect of the ID genotype against BCC may be explained by a possible underlying mechanism involving the effect of produced angiotensin II levels on its receptors due to putatively different binding affinity...
  48. ncbi request reprint Oral carcinogenesis is not achieved in different carcinogen-treated PAI-1 transgenic and wild-type mouse models
    Dimitris Avgoustidis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Athens, Greece
    In Vivo 26:1001-5. 2012
    ..In an effort to assess the role of plasminogen activator inhibitor-1 (PAI-1) in oral squamous cancer development and progression, two different carcinogen treatment protocols were conducted...
  49. ncbi request reprint Cell proliferation and apoptosis culminate in early stages of oral oncogenesis
    S Derka
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Greece
    Oral Oncol 42:540-50. 2006
    ..Finally, Ki-67 expression increased sharply in initial stages of oral carcinogenesis, but significantly decreased in later stages...
  50. ncbi request reprint Potential prevention of thromboembolism by genetic counseling and testing for two common thrombophilia mutations
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, Athens 12461, Greece
    In Vivo 26:165-72. 2012
    ....
  51. ncbi request reprint Are factor V and prothrombin mutations associated with increased risk of oral cancer?
    Eleftherios Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens, Greece
    Anticancer Res 25:2561-5. 2005
    ..Methylenetetrahydrofolate reductase is associated with pathogenesis of both thrombosis and oral cancer. Therefore, a search for a similar association of other thrombosis-related factors with oral cancer is justified...
  52. ncbi request reprint The interleukin-8 (-251A/T) polymorphism is associated with increased risk for oral squamous cell carcinoma
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, GR 11521 Athens, Greece
    Eur J Surg Oncol 33:504-7. 2007
    ..In light of recently found contribution of angiogenic and inflammation-related factors to malignancies, this study investigated the possible association of interleukin-8 gene (IL-8) to increased risk of oral cancer...
  53. ncbi request reprint Prevalence of thrombosis-related DNA polymorphisms in a healthy Greek population
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    In Vivo 26:1095-101. 2012
    ..Knowledge of the prevalence of these variations in a given population may assist in the design of effective preventive measures against cardiovascular disease...
  54. ncbi request reprint Evaluation of apoptosis in nasal and buccal cells of septic patients
    Stavros Vassiliou
    Department of Oral and Maxillofacial Surgery, Attikon Hospital, University of Athens Medical School, Athens, Greece
    In Vivo 21:901-4. 2007
    ..The present study evaluated apoptosis in the nasal and buccal mucosa of septic patients as an alternative and less invasive approach for studying the cells involved in bronchial inflammation...
  55. ncbi request reprint The interplay between hemostasis and malignancy: the oral cancer paradigm
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, Athens 12461, Greece
    Anticancer Res 32:1791-800. 2012
    ..In conclusion, the hemostatic system contributes to the development of the malignant phenotype acting on many different levels...
  56. doi request reprint Genetic association of cytokine DNA polymorphisms with head and neck cancer
    Zoe Serefoglou
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Rimini 1, GR 12462 Athens, Greece
    Oral Oncol 44:1093-9. 2008
    ..It is generally believed that such genetic association studies will gradually increase our knowledge regarding the predisposed manifestation and advancement of these malignancies in the head and neck region...
  57. ncbi request reprint HPV detection rate in saliva may depend on the immune system efficiency
    Maria Adamopoulou
    Department of Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    In Vivo 22:599-602. 2008
    ....
  58. ncbi request reprint Methylenetetrahydrofolate reductase polymorphism and minor increase of risk for oral cancer
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    J Cancer Res Clin Oncol 132:219-22. 2006
    ..Folate deficiency is associated with increased risk for thrombosis, as well as for several types of cancer, through disruption of DNA methylation, DNA synthesis and deficient DNA repair...
  59. ncbi request reprint Prevalence of HPV types in a cohort of Greeks with clinical indication of infection
    Christos Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Attikon Hospital, Athens, Greece
    Anticancer Res 28:2233-7. 2008
    ....
  60. ncbi request reprint The low VEGF production allele of the +936C/T polymorphism is strongly associated with increased risk for oral cancer
    C Yapijakis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens, 11521, Greece
    J Cancer Res Clin Oncol 133:787-91. 2007
    ....
  61. ncbi request reprint Association of platelet glycoprotein Ia polymorphism with minor increase of risk for oral cancer
    E Vairaktaris
    Department of Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Eur J Surg Oncol 32:455-7. 2006
    ....
  62. ncbi request reprint Orbital abscess: visual loss following extraction of a tooth--case report
    Nicholas Zachariades
    Department of Oral and Maxillofacial Surgery, KAT General District Hospital of Attica, Athens, Greece
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:e70-3. 2005
    ..It is the purpose of this article to alert the general practitioner to the severe consequences that may result from a tooth extraction, including the loss of vision, despite the use of antibiotics...
  63. ncbi request reprint Diabetes may increase risk for oral cancer through the insulin receptor substrate-1 and focal adhesion kinase pathway
    L Goutzanis
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Oral Oncol 43:165-73. 2007
    ..These data suggest that the IRS-1/FAK pathway is altered by diabetes resulting in reduced cell adhesion and possibly increasing risk for oral cancer...
  64. ncbi request reprint Cytokeratin 17 mRNA expression has potential for diagnostic marker of oral squamous cell carcinoma
    Takeshi Toyoshima
    Department of Oral and Maxillofacial Surgery, University of Erlangen Nuremberg, Glueckstrasse 11, 91054 Erlangen, Germany
    J Cancer Res Clin Oncol 134:515-21. 2008
    ..Cytokeratins (CKs) like CK 19 and CK 20 are known to be useful diagnostic and prognostic markers for solid tumors. The aim of this study was to evaluate the relevance of further CKs for diagnosis of OSCC...
  65. ncbi request reprint Phosphorylation of Akt (Ser473) predicts poor clinical outcome in oropharyngeal squamous cell cancer
    Ziwei Yu
    Department of Surgery, Yale Cancer Center, P O Box 208032, New Haven, CT 06520, USA
    Cancer Epidemiol Biomarkers Prev 16:553-8. 2007
    ..We sought to determine the prognostic significance of Akt activation in a cohort of patients with OSCC as well as the association between phosphorylated (activated) Akt and PTEN levels...
  66. pmc Expression of MAGE-A12 in oral squamous cell carcinoma
    Nur Mollaoglu
    Department of Oral and Maxillofacial Surgery, Friedrich Alexander University of Erlangen Nuremberg, Gluckstrasse 11, 91054, Erlangen, Germany
    Dis Markers 24:27-32. 2008
    ..In addition, MAGE-A12 expression in OSCC may also determine anew immunotherapeutic target and might be warranted to develop vaccine for OSCC..
  67. doi request reprint Expression of melanoma-associated antigens in oral squamous cell carcinoma
    Jutta Ries
    Department of Oral and Cranio Maxillofacial Surgery, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    J Oral Pathol Med 37:88-93. 2008
    ..Thus, their detection is highly specific to cancer cells, which makes them potential targets for the diagnosis, prognosis and also immunotherapy of neoplastic diseases...
  68. doi request reprint In vitro response of hFOB cells to pamidronate modified sodium silicate coated cellulose scaffolds
    Sabine Ponader
    Department of Oral and Maxillofacial Surgery, University of Erlangen Nuremberg, Erlangen, Germany
    Colloids Surf B Biointerfaces 64:275-83. 2008
    ..Low concentrations of pamidronate seem to have a relevant effect on cell proliferation and vitality and, therefore, can be recommended for the improvement of the properties of a biomaterial...
  69. ncbi request reprint Patient-centred outcomes comparing transmucosal implant placement with an open approach in the maxilla: a prospective, non-randomized pilot study
    Emeka Nkenke
    Department of Oral and Maxillofacial Surgery, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Oral Implants Res 18:197-203. 2007
    ..002). Within the limitations of this pilot study, it could be shown that transmucosal implant placement reduces patient morbidity significantly compared with an open approach...
  70. ncbi request reprint Effects of topographical surface modifications of electron beam melted Ti-6Al-4V titanium on human fetal osteoblasts
    Sabine Ponader
    Department of Oral and Maxillofacial Surgery, University of Erlangen Nuremberg, Erlangen, Germany
    J Biomed Mater Res A 84:1111-9. 2008
    ..9 microm) reduced proliferation of hFOB cells. Surface characteristics of titanium can easily be changed by EBM in order to further improve proliferation...
  71. doi request reprint Vascular mapping of head and neck: computed tomography angiography versus digital subtraction angiography
    Manuel Kramer
    Institute of Diagnostic Radiology, University of Erlangen Nuremberg, Erlangen, Germany
    J Oral Maxillofac Surg 66:302-7. 2008
    ..The aim of the study was to compare multislice computed tomography angiography (MSCTA) to digital subtraction angiography (DSA) for vascular mapping of the head and neck...