Theodore Tzavaras

Summary

Affiliation: University of Ioannina
Country: Greece

Publications

  1. ncbi Factors influencing the expression of endogenous reverse transcriptases and viral-like 30 elements in mouse NIH3T3 cells
    Theodore Tzavaras
    University of Ioannina, Medical School, Laboratory of General Biology, GR 45 110 Ioannina, Greece
    Int J Oncol 23:1237-43. 2003
  2. ncbi Vanadium induces VL30 retrotransposition at an unusually high level: a possible carcinogenesis mechanism
    Dimitrios Noutsopoulos
    Laboratory of General Biology, Medical School, University of Ioannina, 45 110 Ioannina, Greece
    J Mol Biol 374:80-90. 2007
  3. ncbi H2O2 signals via iron induction of VL30 retrotransposition correlated with cytotoxicity
    Sofia Konisti
    Laboratory of General Biology, University of Ioannina, and Hematology Laboratory, Unit of Molecular Biology, University Hospital of Ioannina, 45 110 Ioannina, Greece
    Free Radic Biol Med 52:2072-81. 2012
  4. ncbi VL30 retrotransposition signals activation of a caspase-independent and p53-dependent death pathway associated with mitochondrial and lysosomal damage
    Dimitrios Noutsopoulos
    Laboratory of General Biology, University of Ioannina, Medical School, 45 110 Ioannina, Greece
    Cell Res 20:553-62. 2010
  5. ncbi Retrotransposon RNA expression and evidence for retrotransposition events in human oocytes
    Ioannis Georgiou
    Laboratory of Reproductive Genetics, Medical School, University of Ioannina, Ioannina, Greece
    Hum Mol Genet 18:1221-8. 2009
  6. ncbi Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin
    Soultana Markopoulou
    Cellular and Molecular Physiology Unit, Laboratory of Physiology, School of Medicine, University of Ioannina, Greece
    FEBS J 276:3784-99. 2009
  7. ncbi SV40 large T antigen up-regulates the retrotransposition frequency of viral-like 30 elements
    Dimitrios Noutsopoulos
    Laboratory of General Biology, Medical School, University of Ioannina, 45 110 Ioannina, Greece
    J Mol Biol 361:450-61. 2006
  8. ncbi Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron
    Paschalis Thomas Doulias
    Laboratory of Biological Chemistry, University of Ioannina Medical School, 451 10 Ioannina, Greece
    Free Radic Biol Med 42:567-77. 2007

Collaborators

  • Evangelos Kolettas
  • Ioannis Sainis
  • Dimitrios Noutsopoulos
  • Georgios Markopoulos
  • Georgios Vartholomatos
  • Sofia Konisti
  • Soultana Markopoulou
  • Ioannis Georgiou
  • Nicolaos Kolaitis
  • Paschalis Thomas Doulias
  • Soteroula Thrasyvoulou
  • Stefania Mantziou
  • Christina Batsi
  • Kostas Pantos
  • Terpsi Vaxevanoglou
  • Maria Syrrou
  • Anastasia Apergi
  • Leandros Lazaros
  • Efstathios S Gonos
  • Evangelos Kontargiris
  • Ioannis Trougakos
  • Eftychia Dimitriadou
  • David A Boothman
  • Lefkothea Dova
  • Dimitra Keramisanou
  • Polychronis Kotoglou
  • Dimitrios Galaris
  • Paschalis-Thomas Doulias
  • Maria Koliou
  • Charalampos Angelidis
  • Margarita Tenopoulou
  • Ulf Brunk

Detail Information

Publications8

  1. ncbi Factors influencing the expression of endogenous reverse transcriptases and viral-like 30 elements in mouse NIH3T3 cells
    Theodore Tzavaras
    University of Ioannina, Medical School, Laboratory of General Biology, GR 45 110 Ioannina, Greece
    Int J Oncol 23:1237-43. 2003
    ..Collectively, our results suggest that such stimuli inducing enRTs might play a role in the activation of transcription and retrotransposition of VL30...
  2. ncbi Vanadium induces VL30 retrotransposition at an unusually high level: a possible carcinogenesis mechanism
    Dimitrios Noutsopoulos
    Laboratory of General Biology, Medical School, University of Ioannina, 45 110 Ioannina, Greece
    J Mol Biol 374:80-90. 2007
    ..We propose that VOSO(4)-induced VL30 retrotransposition through H(2)O(2) generation may be an alternative mutagenic, DNA-DSBs independent, mechanism leading to carcinogenesis...
  3. ncbi H2O2 signals via iron induction of VL30 retrotransposition correlated with cytotoxicity
    Sofia Konisti
    Laboratory of General Biology, University of Ioannina, and Hematology Laboratory, Unit of Molecular Biology, University Hospital of Ioannina, 45 110 Ioannina, Greece
    Free Radic Biol Med 52:2072-81. 2012
    ..Our data show for the first time that H2O2, acting via iron, is a potent stimulus of retrotransposition contributing to oxidative stress-induced cell damage...
  4. ncbi VL30 retrotransposition signals activation of a caspase-independent and p53-dependent death pathway associated with mitochondrial and lysosomal damage
    Dimitrios Noutsopoulos
    Laboratory of General Biology, University of Ioannina, Medical School, 45 110 Ioannina, Greece
    Cell Res 20:553-62. 2010
    ....
  5. ncbi Retrotransposon RNA expression and evidence for retrotransposition events in human oocytes
    Ioannis Georgiou
    Laboratory of Reproductive Genetics, Medical School, University of Ioannina, Ioannina, Greece
    Hum Mol Genet 18:1221-8. 2009
    ....
  6. ncbi Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin
    Soultana Markopoulou
    Cellular and Molecular Physiology Unit, Laboratory of Physiology, School of Medicine, University of Ioannina, Greece
    FEBS J 276:3784-99. 2009
    ..In contrast, nCLU sensitized HaCaT cells to apoptosis. Our data suggest that vanadium-mediated apoptosis was promoted by c-fos, leading to alterations in CLU isoform processing and induction of the pro-death nCLU protein...
  7. ncbi SV40 large T antigen up-regulates the retrotransposition frequency of viral-like 30 elements
    Dimitrios Noutsopoulos
    Laboratory of General Biology, Medical School, University of Ioannina, 45 110 Ioannina, Greece
    J Mol Biol 361:450-61. 2006
    ..Our results show a direct correlation between SV40-cell transformation and VL30 retrotransposition and provide for the first time strong evidence that SV40 large T antigen up-regulates the retrotransposition of VL30 elements...
  8. ncbi Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron
    Paschalis Thomas Doulias
    Laboratory of Biological Chemistry, University of Ioannina Medical School, 451 10 Ioannina, Greece
    Free Radic Biol Med 42:567-77. 2007
    ....