Panagiotis Tsirigotis

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint Monoclonal antibodies in the treatment of lymphoid malignancies
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Propaudeutic, University of Athens, Attikon University General Hospital, Athens, Greece
    J Steroid Biochem Mol Biol 108:267-71. 2008
  2. doi request reprint Keratinocyte growth factor is effective in the prevention of intestinal mucositis in patients with hematological malignancies treated with high-dose chemotherapy and autologous hematopoietic SCT: a video-capsule endoscopy study
    P Tsirigotis
    Haematology Unit, Second Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, University of Athens, Athens, Greece
    Bone Marrow Transplant 42:337-43. 2008
  3. ncbi request reprint Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Propaudeutic, University of Athens, Attikon General University Hospital, Athens, Greece
    Rheumatol Int 28:171-4. 2007
  4. ncbi request reprint Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia
    Argirios E Tsantes
    Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, 1 Rimini Str, Athens, Greece
    Blood Coagul Fibrinolysis 22:457-62. 2011
  5. ncbi request reprint Hypermethylation of the p15INK4B gene promoter in B-chronic lymphocytic leukemia
    Sotirios G Papageorgiou
    Second Department of Internal Medicine Propaedeutic, University General Hospital Attikon, Haidari, Greece
    Am J Hematol 82:824-5. 2007
  6. pmc Pure Red Cell Aplasia due to B19 Parvovirus Infection after Autologous Stem Cell Transplantation
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine Propaudeutic, Attikon General University Hospital, University of Athens, P O Box 124 62, Rimini 1, Haidari, Athens, Greece
    Case Rep Transplant 2011:251930. 2011
  7. doi request reprint Extracorporeal photopheresis in refractory chronic graft-versus-host disease: the influence on peripheral blood T cell subpopulations. A study by the Hellenic Association of Hematology
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
    Transfus Apher Sci 46:181-8. 2012
  8. ncbi request reprint Mutational and methylation analysis of the cyclin-dependent kinase 4 inhibitor (p16INK4A) gene in chronic lymphocytic leukemia
    Panagiotis Tsirigotis
    Second Department of Internal Medicine, Propaedeutic, University of Athens, Attikon University General Hospital, Athens, Greece
    Eur J Haematol 76:230-6. 2006
  9. doi request reprint Cell cycle and apoptosis regulatory gene expression in the bone marrow of patients with de novo myelodysplastic syndromes (MDS)
    Christina Economopoulou
    Attikon University Hospital, 2nd Propedeutic Clinic of Internal Medicine, 1 Rimini Str, Haidari, Athens, Greece
    Ann Hematol 89:349-58. 2010
  10. doi request reprint Isolated central nervous system relapses in primary mediastinal large B-cell lymphoma after CHOP-like chemotherapy with or without Rituximab
    Sotirios G Papageorgiou
    Second Department of Internal Medicine, Propaedeutic, Hematology Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital Attikon, Haidari, Greece
    Hematol Oncol 31:10-7. 2013

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Monoclonal antibodies in the treatment of lymphoid malignancies
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Propaudeutic, University of Athens, Attikon University General Hospital, Athens, Greece
    J Steroid Biochem Mol Biol 108:267-71. 2008
    ..However, we need to understand better the mechanisms of its action as well as the mechanisms of resistance to Rit, in order to design more effective treatment modalities...
  2. doi request reprint Keratinocyte growth factor is effective in the prevention of intestinal mucositis in patients with hematological malignancies treated with high-dose chemotherapy and autologous hematopoietic SCT: a video-capsule endoscopy study
    P Tsirigotis
    Haematology Unit, Second Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, University of Athens, Athens, Greece
    Bone Marrow Transplant 42:337-43. 2008
    ..019). KGF is effective in the prevention of intestinal mucositis in patients undergoing auto-SCT. Patients with severe intestinal mucositis run a higher risk to develop infections...
  3. ncbi request reprint Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Propaudeutic, University of Athens, Attikon General University Hospital, Athens, Greece
    Rheumatol Int 28:171-4. 2007
    ..We also review the literature about this interesting relationship between APS and HELLP...
  4. ncbi request reprint Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia
    Argirios E Tsantes
    Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, 1 Rimini Str, Athens, Greece
    Blood Coagul Fibrinolysis 22:457-62. 2011
    ..Our findings demonstrate normalization of platelet function resulting from platelet count reduction in essential thrombocythemia and reinforce the concept of lowering platelet counts in these patients...
  5. ncbi request reprint Hypermethylation of the p15INK4B gene promoter in B-chronic lymphocytic leukemia
    Sotirios G Papageorgiou
    Second Department of Internal Medicine Propaedeutic, University General Hospital Attikon, Haidari, Greece
    Am J Hematol 82:824-5. 2007
    ..Our results suggest that methylation of the p15 gene promoter can be detected in a small subset of B-CLL patients, at all stages of the disease...
  6. pmc Pure Red Cell Aplasia due to B19 Parvovirus Infection after Autologous Stem Cell Transplantation
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine Propaudeutic, Attikon General University Hospital, University of Athens, P O Box 124 62, Rimini 1, Haidari, Athens, Greece
    Case Rep Transplant 2011:251930. 2011
    ..We report a patient with Hodgkin's disease who developed PRCA due to parvovirus B19 after autologous SCT and who had an excellent response after treatment with gamma-globulin...
  7. doi request reprint Extracorporeal photopheresis in refractory chronic graft-versus-host disease: the influence on peripheral blood T cell subpopulations. A study by the Hellenic Association of Hematology
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
    Transfus Apher Sci 46:181-8. 2012
    ..These data further support the concept that ECP does not cause immune-suppression, but should be better considered as an immune-modulating treatment...
  8. ncbi request reprint Mutational and methylation analysis of the cyclin-dependent kinase 4 inhibitor (p16INK4A) gene in chronic lymphocytic leukemia
    Panagiotis Tsirigotis
    Second Department of Internal Medicine, Propaedeutic, University of Athens, Attikon University General Hospital, Athens, Greece
    Eur J Haematol 76:230-6. 2006
    ..The aim of the present study was to determine the frequency of p16 gene deletions and mutations as well as the methylation status of the same gene in CLL patients...
  9. doi request reprint Cell cycle and apoptosis regulatory gene expression in the bone marrow of patients with de novo myelodysplastic syndromes (MDS)
    Christina Economopoulou
    Attikon University Hospital, 2nd Propedeutic Clinic of Internal Medicine, 1 Rimini Str, Haidari, Athens, Greece
    Ann Hematol 89:349-58. 2010
    ..In conclusion, our study showed altered expression of genes involved in apoptosis and cell cycle in MDS and increased expression of cyclin D1 in patients with CMML...
  10. doi request reprint Isolated central nervous system relapses in primary mediastinal large B-cell lymphoma after CHOP-like chemotherapy with or without Rituximab
    Sotirios G Papageorgiou
    Second Department of Internal Medicine, Propaedeutic, Hematology Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital Attikon, Haidari, Greece
    Hematol Oncol 31:10-7. 2013
    ..Established risk factors for CNS involvement in aggressive lymphomas may not be helpful in assessing the risk of CNS recurrence in this disease. Routine CNS prophylaxis is not probably required in PMLBCL...
  11. doi request reprint Management of cutaneous T-Cell lymphoma patients with extracorporeal photopheresis. The Hellenic experience
    Marina P Siakantaris
    1st Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Greece
    Transfus Apher Sci 46:189-93. 2012
    ..Median survival was 51 months, progression free survival was 28 months and response duration was 29 ± 23.9 months. ECP combined therapy was highly effective or had a palliative effect in CTCL resistant to previous treatments...
  12. doi request reprint The role of the Platelet Function Analyzer (PFA)-100 and platelet aggregometry in the differentiation of essential thrombocythemia from reactive thrombocytosis
    Argirios E Tsantes
    Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Athens, Greece
    Thromb Res 125:142-6. 2010
    ..Our aim was to evaluate the diagnostic performance of the PFA-100 collagen-epinephrine (CEPI) cartridge test and epinephrine-induced aggregometry individually, but mainly combined, in the differentiation of ET from RT...
  13. doi request reprint Update on the mechanism of action and on clinical efficacy of extracorporeal photopheresis in the treatment of acute and chronic graft versus host disease in children
    Evgenios Goussetis
    Stem Cell Transplant Unit, Aghia Sophia Children s Hospital, Athens, Greece
    Transfus Apher Sci 46:203-9. 2012
    ..Reviewing these data we conclude that ECP is a safe procedure, well tolerated even in low-weight pediatric patients, which warrants further evaluation in well-designed, prospective, controlled studies...
  14. ncbi request reprint Irradiated mononuclear cells express significant in vitro cytotoxic activity: promise for in vivo clinical efficacy of irradiated mismatched donor lymphocytes infusion
    Panagiotis Tsirigotis
    Second Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Greece
    Immunotherapy 6:409-17. 2014
    ..Patients who relapse post-allo-SCT can achieve prolonged remission after donor lymphocyte infusion. Donor lymphocyte infusion as well as other immunotherapeutic strategies are usually complicated by severe graft versus host disease...
  15. doi request reprint Rosuvastatin-induced thrombocytopenia
    Ioannis Vrettos
    Second Department of Internal Medicine, Propaedeutic, University of Athens, Medical School, Attikon University General Hospital, Haidari, Athens, Greece
    South Med J 103:676-8. 2010
    ..One rare complication of statin treatment is severe thrombocytopenia. The case of a 65-year-old patient who developed severe thrombocytopenia while on rosuvastatin is presented, in addition to a review of the literature...
  16. ncbi request reprint 2-deoxycoformycin in the treatment of T-large granular lymphocyte leukemia
    Panagiotis Tsirigotis
    Third Department of Internal Medicine, First Hospital of Athens, Social Insurance Foundation, Zaimi Street Melissia, 15127 Athens, Greece
    Leuk Res 27:865-7. 2003
    ..Flow cytometric analysis of TCR-Vbeta repertoire proved to be an effective method to assess the therapeutic response to various treatments and to evaluate residual disease...
  17. pmc Lobomycosis: A case from Southeastern Europe and review of the literature
    Evangelia Papadavid
    2nd Department of Dermatology, Athens University School of Medicine, Attikon General University Hospital, Chaidari, Athens, Greece
    J Dermatol Case Rep 6:65-9. 2012
    ..More than 550 human cases have been reported, especially in patients with a history of travel or residence in endemic areas (Central and South America, particularly Brazil) or in communities along rivers...
  18. doi request reprint The nature of small intestinal mucositis: a video-capsule endoscopy study
    Konstantinos Triantafyllou
    Hepatogastroenterology, 2nd Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, Athens University, Athens, Greece
    Support Care Cancer 16:1173-8. 2008
    ..The aim of our study was to investigate small intestinal lesions using video-capsule endoscopy in patients undergoing peripheral blood stem cells transplantation...
  19. doi request reprint Expression analysis of proteins involved in the non homologous end joining DNA repair mechanism, in the bone marrow of adult de novo myelodysplastic syndromes
    Panagiota Economopoulou
    Second Department of Internal Medicine, Propaedeutic, University of Athens, Medical School, University General Hospital Attikon, 12 462 Haidari, Greece
    Ann Hematol 89:233-9. 2010
    ..04). Our findings suppor-t a potential role of NHEJ enzyme Ligase IV in the pathogenesis of MDS. Larger numbers of cases need to be screened in order to draw definite conclusion...
  20. pmc Clinical reasoning: a 51-year-old man with cervical pain and progressively deteriorating gait
    Dimitrios Rallis
    2ns Department of Neurology, Attiko University Hospital, Medical School, University of Athens, Athens, Greece
    Neurology 80:e230-4. 2013
    ..No previous trauma was recalled. His medical and family history was unremarkable except for hypertension that was treated with angiotensin-converting enzyme inhibitors...
  21. doi request reprint Monitoring aspirin treatment in patients with thrombocytosis: comparison of the platelet function analyzer (PFA)-100 with optical aggregometry
    Argirios E Tsantes
    Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Greece
    Thromb Res 123:100-7. 2008
    ..It still remains to determine whether there is any relevance between the measurements obtained by these methods and clinical outcome in thrombocythemic patients...
  22. doi request reprint The role of extracorporeal photopheresis in the treatment of cutaneous T-cell lymphomas
    Maria Atta
    2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
    Transfus Apher Sci 46:195-202. 2012
    ..Considering the high cost of the procedure, the role of ECP in the treatment of SS/MF needs to be clarified via well designed multicenter prospective randomized trials...
  23. doi request reprint Extracorporeal photopheresis in the treatment of chronic graft-versus-host disease. The Hellenic experience: a study by the Hellenic association of hematology
    Panagiotis Tsirigotis
    2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
    Transfus Apher Sci 46:173-80. 2012
    ..1, CI 95% 0.1-0.7, p=0.02). ECP should be tested as first-line treatment in patients with cGVHD with the aim to minimize the duration of immunosuppression and the rate of relapse of the malignant disease...
  24. ncbi request reprint Absence of p16 and p27 gene rearrangements and mutations in de novo myelodysplastic syndromes
    Sotirios G Papageorgiou
    Second Department of Internal Medicine Propaedeutic, Athens University Medical School, Attikon General Hospital, Haidari, Greece
    Eur J Haematol 75:193-8. 2005
    ..Our results suggest that mutations of p16 and p27 genes resulting in abnormal p16 and p27 proteins do not represent a mechanism of gene inactivation involved in the pathogenesis of MDS...