Research Topics
Species | Panagiotis TsirigotisSummaryAffiliation: University of Athens Country: Greece Publications
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Detail Information
Publications
Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndromePanagiotis Tsirigotis
2nd Department of Internal Medicine, Propaudeutic, University of Athens, Attikon General University Hospital, Athens, Greece
Rheumatol Int 28:171-4. 2007..We also review the literature about this interesting relationship between APS and HELLP...
Monoclonal antibodies in the treatment of lymphoid malignanciesPanagiotis Tsirigotis
2nd Department of Internal Medicine, Propaudeutic, University of Athens, Attikon University General Hospital, Athens, Greece
J Steroid Biochem Mol Biol 108:267-71. 2008..However, we need to understand better the mechanisms of its action as well as the mechanisms of resistance to Rit, in order to design more effective treatment modalities...
Keratinocyte growth factor is effective in the prevention of intestinal mucositis in patients with hematological malignancies treated with high-dose chemotherapy and autologous hematopoietic SCT: a video-capsule endoscopy studyP Tsirigotis
Haematology Unit, Second Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, University of Athens, Athens, Greece
Bone Marrow Transplant 42:337-43. 2008..019). KGF is effective in the prevention of intestinal mucositis in patients undergoing auto-SCT. Patients with severe intestinal mucositis run a higher risk to develop infections...
Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemiaArgirios E Tsantes
Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, 1 Rimini Str, Athens, Greece
Blood Coagul Fibrinolysis 22:457-62. 2011..Our findings demonstrate normalization of platelet function resulting from platelet count reduction in essential thrombocythemia and reinforce the concept of lowering platelet counts in these patients...
Hypermethylation of the p15INK4B gene promoter in B-chronic lymphocytic leukemiaSotirios G Papageorgiou
Second Department of Internal Medicine Propaedeutic, University General Hospital Attikon, Haidari, Greece
Am J Hematol 82:824-5. 2007..Our results suggest that methylation of the p15 gene promoter can be detected in a small subset of B-CLL patients, at all stages of the disease...
Pure Red Cell Aplasia due to B19 Parvovirus Infection after Autologous Stem Cell TransplantationPanagiotis Tsirigotis
2nd Department of Internal Medicine Propaudeutic, Attikon General University Hospital, University of Athens, P O Box 124 62, Rimini 1, Haidari, Athens, Greece
Case Rep Transplant 2011:251930. 2011..We report a patient with Hodgkin's disease who developed PRCA due to parvovirus B19 after autologous SCT and who had an excellent response after treatment with gamma-globulin...
Extracorporeal photopheresis in refractory chronic graft-versus-host disease: the influence on peripheral blood T cell subpopulations. A study by the Hellenic Association of HematologyPanagiotis Tsirigotis
2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
Transfus Apher Sci 46:181-8. 2012..These data further support the concept that ECP does not cause immune-suppression, but should be better considered as an immune-modulating treatment...
Cell cycle and apoptosis regulatory gene expression in the bone marrow of patients with de novo myelodysplastic syndromes (MDS)Christina Economopoulou
Attikon University Hospital, 2nd Propedeutic Clinic of Internal Medicine, 1 Rimini Str, Haidari, Athens, Greece
Ann Hematol 89:349-58. 2010..In conclusion, our study showed altered expression of genes involved in apoptosis and cell cycle in MDS and increased expression of cyclin D1 in patients with CMML...
Mutational and methylation analysis of the cyclin-dependent kinase 4 inhibitor (p16INK4A) gene in chronic lymphocytic leukemiaPanagiotis Tsirigotis
Second Department of Internal Medicine, Propaedeutic, University of Athens, Attikon University General Hospital, Athens, Greece
Eur J Haematol 76:230-6. 2006..The aim of the present study was to determine the frequency of p16 gene deletions and mutations as well as the methylation status of the same gene in CLL patients...
Isolated central nervous system relapses in primary mediastinal large B-cell lymphoma after CHOP-like chemotherapy with or without RituximabSotirios G Papageorgiou
Second Department of Internal Medicine, Propaedeutic, Hematology Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital Attikon, Haidari, Greece
Hematol Oncol 31:10-7. 2013..Established risk factors for CNS involvement in aggressive lymphomas may not be helpful in assessing the risk of CNS recurrence in this disease. Routine CNS prophylaxis is not probably required in PMLBCL...
Management of cutaneous T-Cell lymphoma patients with extracorporeal photopheresis. The Hellenic experienceMarina P Siakantaris
1st Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Greece
Transfus Apher Sci 46:189-93. 2012..Median survival was 51 months, progression free survival was 28 months and response duration was 29 ± 23.9 months. ECP combined therapy was highly effective or had a palliative effect in CTCL resistant to previous treatments...
The role of the Platelet Function Analyzer (PFA)-100 and platelet aggregometry in the differentiation of essential thrombocythemia from reactive thrombocytosisArgirios E Tsantes
Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Athens, Greece
Thromb Res 125:142-6. 2010..Our aim was to evaluate the diagnostic performance of the PFA-100 collagen-epinephrine (CEPI) cartridge test and epinephrine-induced aggregometry individually, but mainly combined, in the differentiation of ET from RT...
Update on the mechanism of action and on clinical efficacy of extracorporeal photopheresis in the treatment of acute and chronic graft versus host disease in childrenEvgenios Goussetis
Stem Cell Transplant Unit, Aghia Sophia Children s Hospital, Athens, Greece
Transfus Apher Sci 46:203-9. 2012..Reviewing these data we conclude that ECP is a safe procedure, well tolerated even in low-weight pediatric patients, which warrants further evaluation in well-designed, prospective, controlled studies...
Rosuvastatin-induced thrombocytopeniaIoannis Vrettos
Second Department of Internal Medicine, Propaedeutic, University of Athens, Medical School, Attikon University General Hospital, Haidari, Athens, Greece
South Med J 103:676-8. 2010..One rare complication of statin treatment is severe thrombocytopenia. The case of a 65-year-old patient who developed severe thrombocytopenia while on rosuvastatin is presented, in addition to a review of the literature...
2-deoxycoformycin in the treatment of T-large granular lymphocyte leukemiaPanagiotis Tsirigotis
Third Department of Internal Medicine, First Hospital of Athens, Social Insurance Foundation, Zaimi Street Melissia, 15127 Athens, Greece
Leuk Res 27:865-7. 2003..Flow cytometric analysis of TCR-Vbeta repertoire proved to be an effective method to assess the therapeutic response to various treatments and to evaluate residual disease...
Lobomycosis: A case from Southeastern Europe and review of the literatureEvangelia Papadavid
2nd Department of Dermatology, Athens University School of Medicine, Attikon General University Hospital, Chaidari, Athens, Greece
J Dermatol Case Rep 6:65-9. 2012..More than 550 human cases have been reported, especially in patients with a history of travel or residence in endemic areas (Central and South America, particularly Brazil) or in communities along rivers...
The nature of small intestinal mucositis: a video-capsule endoscopy studyKonstantinos Triantafyllou
Hepatogastroenterology, 2nd Department of Internal Medicine Propaedeutic, Attikon University General Hospital, Medical School, Athens University, Athens, Greece
Support Care Cancer 16:1173-8. 2008..The aim of our study was to investigate small intestinal lesions using video-capsule endoscopy in patients undergoing peripheral blood stem cells transplantation...
Expression analysis of proteins involved in the non homologous end joining DNA repair mechanism, in the bone marrow of adult de novo myelodysplastic syndromesPanagiota Economopoulou
Second Department of Internal Medicine, Propaedeutic, University of Athens, Medical School, University General Hospital Attikon, 12 462 Haidari, Greece
Ann Hematol 89:233-9. 2010..04). Our findings suppor-t a potential role of NHEJ enzyme Ligase IV in the pathogenesis of MDS. Larger numbers of cases need to be screened in order to draw definite conclusion...
Monitoring aspirin treatment in patients with thrombocytosis: comparison of the platelet function analyzer (PFA)-100 with optical aggregometryArgirios E Tsantes
Laboratory of Haematology and Blood Bank Unit, Attikon General Hospital, School of Medicine, University of Athens, Greece
Thromb Res 123:100-7. 2008..It still remains to determine whether there is any relevance between the measurements obtained by these methods and clinical outcome in thrombocythemic patients...
The role of extracorporeal photopheresis in the treatment of cutaneous T-cell lymphomasMaria Atta
2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
Transfus Apher Sci 46:195-202. 2012..Considering the high cost of the procedure, the role of ECP in the treatment of SS/MF needs to be clarified via well designed multicenter prospective randomized trials...
Extracorporeal photopheresis in the treatment of chronic graft-versus-host disease. The Hellenic experience: a study by the Hellenic association of hematologyPanagiotis Tsirigotis
2nd Department of Internal Medicine, Attikon General University Hospital, Medical School, University of Athens, Greece
Transfus Apher Sci 46:173-80. 2012..1, CI 95% 0.1-0.7, p=0.02). ECP should be tested as first-line treatment in patients with cGVHD with the aim to minimize the duration of immunosuppression and the rate of relapse of the malignant disease...
Absence of p16 and p27 gene rearrangements and mutations in de novo myelodysplastic syndromesSotirios G Papageorgiou
Second Department of Internal Medicine Propaedeutic, Athens University Medical School, Attikon General Hospital, Haidari, Greece
Eur J Haematol 75:193-8. 2005..Our results suggest that mutations of p16 and p27 genes resulting in abnormal p16 and p27 proteins do not represent a mechanism of gene inactivation involved in the pathogenesis of MDS...
