Agathocles Tsatsoulis

Summary

Affiliation: University of Ioannina
Country: Greece

Publications

  1. ncbi request reprint The effect of thyrotoxicosis on adrenocortical reserve
    A Tsatsoulis
    Endocrine Unit, Department of Medicine, University of Ioannina School of Medicine, Ioannina, 451 10, Greece
    Eur J Endocrinol 142:231-5. 2000
  2. ncbi request reprint Thyroid autoimmunity is associated with higher urinary iodine concentrations in an iodine-deficient area of Northwestern Greece
    A Tsatsoulis
    Department of Medicine, Endocrine Unit, University of Ioannina, Medical School, Greece
    Thyroid 9:279-83. 1999
  3. ncbi request reprint Study of growth hormone secretion and action in growth-retarded children with juvenile chronic arthritis (JCA)
    A Tsatsoulis
    Endocrine Unit, Department of Medicine, Department of Paediatrics, University of Ioannina, Ioannina, Greece
    Growth Horm IGF Res 9:143-9. 1999
  4. ncbi request reprint Turner's syndrome with concomitant hypopituitarism: case report
    Z Efstathiadou
    Endocrine Unit, Department of Internal Medicine, University Hospital of Ioannina, Ioannina, Greece
    Hum Reprod 15:2388-9. 2000
  5. ncbi request reprint The role of apoptosis in thyroid disease
    A Tsatsoulis
    Department of Medicine, Division of Endocrinology, University of Ioannina, Ioannina, Greece
    Minerva Med 93:169-80. 2002
  6. ncbi request reprint The role of stress in the clinical expression of thyroid autoimmunity
    Agathocles Tsatsoulis
    Department of Endocrinology, University of Ioannina, 45110, Ioannina, Greece
    Ann N Y Acad Sci 1088:382-95. 2006
  7. doi request reprint Effects of pioglitazone and metformin on vascular endothelial function in patients with type 2 diabetes treated with sulfonylureas
    Katerina K Naka
    Department of Cardiology, University of Ioannina, Ioannina, Greece
    Diab Vasc Dis Res 9:52-8. 2012
  8. doi request reprint Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: a prospective randomized study
    Katerina K Naka
    Michaelidion Cardiac Center, Department of Cardiology, University of Ioannina, Ioannina, Greece
    Fertil Steril 95:203-9. 2011
  9. doi request reprint Rosiglitazone improves endothelial function in patients with type 2 diabetes treated with insulin
    Katerina K Naka
    Michaelidion Cardiac Centre, University of Ioannina, Greece
    Diab Vasc Dis Res 8:195-201. 2011
  10. pmc Determinants of vascular function in patients with type 2 diabetes
    Katerina K Naka
    Michaelidion Cardiac Center, University of Ioannina, Ioannina, Greece
    Cardiovasc Diabetol 11:127. 2012

Collaborators

Detail Information

Publications58

  1. ncbi request reprint The effect of thyrotoxicosis on adrenocortical reserve
    A Tsatsoulis
    Endocrine Unit, Department of Medicine, University of Ioannina School of Medicine, Ioannina, 451 10, Greece
    Eur J Endocrinol 142:231-5. 2000
    ..This study aimed to assess adrenocortical reserve in response to low-dose ACTH, following dexamethasone suppression, in patients with severe thyrotoxicosis...
  2. ncbi request reprint Thyroid autoimmunity is associated with higher urinary iodine concentrations in an iodine-deficient area of Northwestern Greece
    A Tsatsoulis
    Department of Medicine, Endocrine Unit, University of Ioannina, Medical School, Greece
    Thyroid 9:279-83. 1999
    ..However, it appears that autoimmune thyroiditis is emerging as a frequent cause of goiter in those children with sufficient iodine intake...
  3. ncbi request reprint Study of growth hormone secretion and action in growth-retarded children with juvenile chronic arthritis (JCA)
    A Tsatsoulis
    Endocrine Unit, Department of Medicine, Department of Paediatrics, University of Ioannina, Ioannina, Greece
    Growth Horm IGF Res 9:143-9. 1999
    ....
  4. ncbi request reprint Turner's syndrome with concomitant hypopituitarism: case report
    Z Efstathiadou
    Endocrine Unit, Department of Internal Medicine, University Hospital of Ioannina, Ioannina, Greece
    Hum Reprod 15:2388-9. 2000
    ..This case illustrates that the co-existence of primary and secondary hypogonadism may obscure and delay the diagnosis of Turner's syndrome, a diagnosis which alters the counselling of the patient from the reproductive perspective...
  5. ncbi request reprint The role of apoptosis in thyroid disease
    A Tsatsoulis
    Department of Medicine, Division of Endocrinology, University of Ioannina, Ioannina, Greece
    Minerva Med 93:169-80. 2002
    ..However, the exact mechanisms involved in the regulation of apoptosis in thyroid disease remain unclear. Further investigation is needed that may provide new strategies in the prevention and treatment of these diseases...
  6. ncbi request reprint The role of stress in the clinical expression of thyroid autoimmunity
    Agathocles Tsatsoulis
    Department of Endocrinology, University of Ioannina, 45110, Ioannina, Greece
    Ann N Y Acad Sci 1088:382-95. 2006
    ..Conversely, recovery from stress or the immune suppressive effect of pregnancy may induce a Th2 to Th1 "return shift" leading to autoimmune (sporadic) or postpartum thyroiditis, respectively...
  7. doi request reprint Effects of pioglitazone and metformin on vascular endothelial function in patients with type 2 diabetes treated with sulfonylureas
    Katerina K Naka
    Department of Cardiology, University of Ioannina, Ioannina, Greece
    Diab Vasc Dis Res 9:52-8. 2012
    ..The beneficial effects of pioglitazone and metformin on endothelial function in T2DM patients did not differ greatly. Larger studies are needed to explore whether a potentially greater benefit with pioglitazone may exist...
  8. doi request reprint Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: a prospective randomized study
    Katerina K Naka
    Michaelidion Cardiac Center, Department of Cardiology, University of Ioannina, Ioannina, Greece
    Fertil Steril 95:203-9. 2011
    ..To compare the effect of two different insulin sensitizers, metformin and pioglitazone, on endothelial function in women with polycystic ovary syndrome (PCOS)...
  9. doi request reprint Rosiglitazone improves endothelial function in patients with type 2 diabetes treated with insulin
    Katerina K Naka
    Michaelidion Cardiac Centre, University of Ioannina, Greece
    Diab Vasc Dis Res 8:195-201. 2011
    ..Further research is needed to investigate why this beneficial effect does not translate into improved cardiovascular prognosis in these patients...
  10. pmc Determinants of vascular function in patients with type 2 diabetes
    Katerina K Naka
    Michaelidion Cardiac Center, University of Ioannina, Ioannina, Greece
    Cardiovasc Diabetol 11:127. 2012
    ..The aim of our study was to investigate the predictors of vascular dysfunction in T2DM patients...
  11. pmc Lack of effects of pioglitazone on cardiac function in patients with type 2 diabetes and evidence of left ventricular diastolic dysfunction: a tissue doppler imaging study
    Katerina K Naka
    Michaelidion Cardiac Center, University of Ioannina, University Campus, Ioannina, Greece
    Cardiovasc Diabetol 9:57. 2010
    ..We sought to investigate the effects of pioglitazone on novel echocardiographic indices of left ventricular (LV) diastolic function in DM2 patients with LV diastolic dysfunction (LVDD)...
  12. doi request reprint HLA-DR expressing peripheral T regulatory cells in newly diagnosed patients with different forms of autoimmune thyroid disease
    Stelios Fountoulakis
    Department of Endocrinology, University of Ioannina, Medical School, Ioannina, Greece
    Thyroid 18:1195-200. 2008
    ..The aim of the present study was to examine whether changes in the number of peripheral CD4 + CD25highHLA-DR + lymphocytes, a subpopulation of Tregs, occur in patients with AITD...
  13. ncbi request reprint Natural course of autoimmune thyroiditis after elimination of iodine deficiency in northwestern Greece
    Christos Zois
    Department of Endocrinology, University Hospital of Ioannina, Ioannina, Greece
    Thyroid 16:289-93. 2006
    ..In conclusion, both antibody types increased in frequency and level, but TPOAbs were the predominant autoimmunity marker predictive of impending thyroid failure in children with AIT, as was thyroid hypoechogenicity on ultrasound...
  14. ncbi request reprint CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype
    Nectaria Xita
    Department of Endocrinology, University of Ioannina, Ioannina, Greece
    Fertil Steril 94:250-4. 2010
    ..To evaluate the possible contribution of the (TTTA)n polymorphism of aromatase gene (CYP19) to the hyperandrogenic phenotype of polycystic ovary syndrome (PCOS)...
  15. ncbi request reprint Effect of ethinylestradiol/cyproterone acetate on endothelial function in young non-obese women with polycystic ovary syndrome: a pilot study
    Katerina K Naka
    Department of Cardiology, University of Ioannina, Ioannina, Greece
    Gynecol Endocrinol 27:615-21. 2011
    ..Combined oral contraceptives are used in polycystic ovary syndrome (PCOS) women for the treatment of hyperandrogenism and menstrual cycle disturbances...
  16. ncbi request reprint The Pro12Ala polymorphism of the PPAR-gamma gene is not associated with the polycystic ovary syndrome
    Nectaria Xita
    Department of Endocrinology, University of Ioannina, Ioannina, Greece
    Hormones (Athens) 8:267-72. 2009
    ..The aim of the study was to investigate the possible involvement of the Pro12Ala polymorphism of the PPAR-gamma gene in the pathogenesis of PCOS...
  17. doi request reprint Association of the A1330V and V667M polymorphisms of LRP5 with bone mineral density in Greek peri- and postmenopausal women
    Anastasia E Markatseli
    Department of Endocrinology, University of Ioannina, Ioannina, Greece
    Maturitas 70:188-93. 2011
    ..Wnt signaling through low-density lipoprotein receptor-related protein 5 (LRP5) is an important determinant of bone mass regulation...
  18. doi request reprint The synergistic effect of sex hormone-binding globulin and aromatase genes on polycystic ovary syndrome phenotype
    Nectaria Xita
    Department of Endocrinology, University of Ioannina, Ioannina 45110, Greece
    Eur J Endocrinol 158:861-5. 2008
    ....
  19. ncbi request reprint Serum levels of soluble fas in patients with multinodular goiter
    Maria Andrikoula
    Department of Endocrinology, University Hospital of Ioannina, Dourouti, Ioannina, Greece
    Immunol Invest 38:398-407. 2009
    ..The aim of this study was to examine whether sFas is differentially expressed in multinodular goiter (MNG), which is associated with decreased Fas-mediated apoptosis...
  20. ncbi request reprint Thyroid substitution therapy induces high-density lipoprotein-associated platelet-activating factor-acetylhydrolase in patients with subclinical hypothyroidism: a potential antiatherogenic effect
    Haralampos J Milionis
    Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece
    Thyroid 15:455-60. 2005
    ..Plasma paraoxonase 1 (PON1) is an esterase exclusively associated with HDL...
  21. ncbi request reprint Association of the (TAAAA)n repeat polymorphism of SHBG gene with the age at menopause in Greek postmenopausal women
    Anastasia E Markatseli
    Department of Endocrinology, University of Ioannina, 45110 Ioannina, Greece
    Maturitas 78:113-6. 2014
    ..To assess the potential association of the pentanucleotide (TAAAA)n repeat polymorphism in the promoter of SHBG gene with the age at menopause in a Greek female population...
  22. ncbi request reprint PROP-1 gene mutations in a 63-year-old woman presenting with osteoporosis and hyperlipidaemia
    Maria Andrikoula
    Department of Endocrinology, University Hospital of Ioannina, Ioannina, Greece
    Hormones (Athens) 12:128-34. 2013
    ....
  23. ncbi request reprint High prevalence of autoimmune thyroiditis in schoolchildren after elimination of iodine deficiency in northwestern Greece
    Christos Zois
    Division of Endocrinology, Department of Medicine, University of Ioannina, Greece
    Thyroid 13:485-9. 2003
    ..In conclusion, silent iodine prophylaxis has resulted in the elimination of iodine deficiency in Greece, and this has been accompanied by an increase in the prevalence of autoimmune thyroiditis...
  24. ncbi request reprint Association of the (TTTA)n repeat polymorphism of CYP19 gene with bone mineral density in Greek peri- and postmenopausal women
    Anastasia E Markatseli
    Department of Endocrinology, University of Ioannina, Ioannina, Greece
    Clin Endocrinol (Oxf) 81:38-44. 2014
    ..CYP19 gene polymorphisms have been studied for their association with bone mineral density (BMD) in the general population with mixed results...
  25. doi request reprint Differential expression of Fas system apoptotic molecules in peripheral lymphocytes from patients with Graves' disease and Hashimoto's thyroiditis
    Stelios Fountoulakis
    Department of Endocrinology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Eur J Endocrinol 158:853-9. 2008
    ..To examine whether the Fas system apoptotic molecules are differentially expressed in Graves' disease (GD) and Hashimoto's thyroiditis (HT), the two opposite phenotypes of autoimmune thyroid disease (AITD)...
  26. doi request reprint Genetic variants of sex hormone-binding globulin and their biological consequences
    Nectaria Xita
    Department of Endocrinology, University of Ioannina, Ioannina, Greece
    Mol Cell Endocrinol 316:60-5. 2010
    ..However, the weight of evidence suggests that some common genetic variants of SHBG may influence SHBG levels and in part contribute to the phenotypic expression of human diseases...
  27. ncbi request reprint The role of iodine in the evolution of thyroid disease in Greece: from endemic goiter to thyroid autoimmunity
    Stelios Fountoulakis
    Department of Endocrinology, University of Ioannina, Ioannina, Greece
    Hormones (Athens) 6:25-35. 2007
    ....
  28. doi request reprint Pioglitazone vs glimepiride: Differential effects on vascular endothelial function in patients with type 2 diabetes
    Katerina Papathanassiou
    Michaelidion Cardiac Center, University of Ioannina, Ioannina, Greece
    Atherosclerosis 205:221-6. 2009
    ..The aim of this study was to compare the effect of glimepiride and pioglitazone on endothelial function in patients with type 2 diabetes already on metformin...
  29. ncbi request reprint Sex steroids and sex hormone-binding globulin in postmenopausal women with nonalcoholic fatty liver disease
    Stergios A Polyzos
    Department of Medicine, Second Medical Clinic, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Greece
    Hormones (Athens) 12:405-16. 2013
    ..The evaluation of serum sex steroids and sex hormone-binding globulin (SHBG) levels in postmenopausal women with nonalcoholic fatty liver disease (NAFLD) and their association to the disease severity...
  30. ncbi request reprint PROP-1 gene mutations in a 63-year-old woman presenting with osteoporosis and hyperlipidaemia
    Maria Andrikoula
    Department of Endocrinology, University Hospital of Ioannina, Ioannina, Greece
    Hormones (Athens) 12:128-34. 2013
    ....
  31. ncbi request reprint Hypokalemic paralysis following administration of intravenous methylprednisolone in a patient with Graves' thyrotoxicosis and ophthalmopathy
    Stelios Tigas
    Department of Endocrinology, University of Ioannina, Greece
    Hormones (Athens) 10:313-6. 2011
    ..Clinicians should exercise caution when administering high-dose glucocorticoids during thyrotoxicosis as there is a risk of provoking hypokalemic paralysis in susceptible patients...
  32. ncbi request reprint The protective role of exercise on stress system dysregulation and comorbidities
    Agathocles Tsatsoulis
    Department of Endocrinology, University of Ioannina, Ioannina 45110, Greece
    Ann N Y Acad Sci 1083:196-213. 2006
    ..The way to prevent and combat this burden is by regular exercise...
  33. doi request reprint Association of serum and follicular fluid SHBG levels and SHBG (TAAAA)n polymorphism with follicle size in women undergoing ovarian stimulation
    Elissavet Hatzi
    Department of Obstetrics Gynecology, Medical School, University of Ioannina, Ioannina, Greece
    Gynecol Endocrinol 27:27-32. 2011
    ..The aim of this study was to investigate whether serum and follicular fluid SHBG levels and SHBG (TAAAA)(n) polymorphism are related to follicle size and pregnancy rate in women undergoing in vitro fertilisation...
  34. ncbi request reprint A study of the growth-promoting and metabolic effects of growth hormone (GH) in a patient with the "growth without GH" syndrome
    M Pavlou
    Department of Paediatrics, University of Ioannina, 45110 Ioannina, Greece
    Growth Horm IGF Res 11:225-30. 2001
    ..In conclusion, our case study suggests that, in the "growth without GH" syndrome, the excessive growth is independent of GH and dissociated from other GH-dependent metabolic effects, which are decreased...
  35. ncbi request reprint The adiponectin-to-leptin ratio in women with polycystic ovary syndrome: relation to insulin resistance and proinflammatory markers
    Nectaria Xita
    Department of Endocrinology, University of Ioannina, 45110 Ioannina, Greece
    Metabolism 56:766-71. 2007
    ..570, P = .001 in overweight-obese women). In conclusion, the A/L ratio may serve as a biomarker of both insulin resistance and low-grade inflammation, providing the link between these cardiovascular risk factors in women with PCOS...
  36. ncbi request reprint On the pathogenesis of autoimmune thyroid disease: a unifying hypothesis
    Stelios Fountoulakis
    Division of Endocrinology, Department of Medicine, University of Ioannina, Ioannina, Greece
    Clin Endocrinol (Oxf) 60:397-409. 2004
  37. ncbi request reprint Molecular genetic aspects and pathophysiology of endocrine hypertension
    Stelios Fountoulakis
    Department of Endocrinology, University of Ioannina Medical School, Ioannina, Greece
    Hormones (Athens) 5:90-106. 2006
  38. doi request reprint Insulin resistance: an adaptive mechanism becomes maladaptive in the current environment - an evolutionary perspective
    Agathocles Tsatsoulis
    Department of Endocrinology, Medical School, University of Ioannina, 45110 Ioannina, Greece
    Metabolism 62:622-33. 2013
    ....
  39. ncbi request reprint Fas and Bcl-2 protein expression in thyrocytes of patients with nodular goiter
    M Andrikoula
    Division of Endocrinology, Department of Medicine, University of Ioannina, 45 110 Ioannina, Greece
    Eur J Endocrinol 145:403-7. 2001
    ..The regulation of Bcl-2 protein differs between adenomatous and colloid nodules, suggesting that this protein may play a role in the differentiation of thyroid nodules...
  40. ncbi request reprint Lipid profile in subclinical hypothyroidism: is L-thyroxine substitution beneficial?
    Z Efstathiadou
    Division of Endocrinology, University of Ioannina School of Medicine, University Hospital of Ioannina, Ioannina, Greece
    Eur J Endocrinol 145:705-10. 2001
    ..The present study aimed to assess the association of SH with lipid abnormalities and to quantify the effect of L-thyroxine therapy on serum lipid profiles...
  41. ncbi request reprint Lipoprotein (a) levels and apolipoprotein (a) isoform size in patients with subclinical hypothyroidism: effect of treatment with levothyroxine
    Haralampos J Milionis
    Department of Internal Medicine, Medical School of Ioannina, Ioannina, Greece
    Thyroid 13:365-9. 2003
    ....
  42. ncbi request reprint Predictors of endothelial dysfunction in young women with polycystic ovary syndrome
    Maria Kravariti
    F R C P, Department of Endocrinology, University of Ioannina, Panepistimiou Avenue, 45 110 Ioannina, Greece
    J Clin Endocrinol Metab 90:5088-95. 2005
    ..Women with polycystic ovary syndrome (PCOS) may be at increased risk for cardiovascular disease. Endothelial dysfunction is an early marker of atherosclerosis...
  43. doi request reprint Active Paget's disease of bone with normal biomarkers of bone metabolism: a case report and review of the literature
    Lamprini Gkouva
    Department of Endocrinology, University Hospital of Ioannina, Dim Hatzi 68, Ioannina, 45445, Greece
    Clin Rheumatol 30:139-44. 2011
    ....
  44. ncbi request reprint Phenotypic and molecular genetic aspects of pseudohypoparathyroidism type Ib in a Greek kindred: evidence for enhanced uric acid excretion due to parathyroid hormone resistance
    Elena Laspa
    Department of Medicine, Division of Endocrinology, University of Ioannina, 45110 Ioannina, Greece
    J Clin Endocrinol Metab 89:5942-7. 2004
    ..Furthermore, affected individuals displayed hypouricemia with increased fractional excretion of uric acid, suggesting possible involvement of PTH in the renal handling of this metabolite...
  45. ncbi request reprint Review: fetal programming of polycystic ovary syndrome by androgen excess: evidence from experimental, clinical, and genetic association studies
    Nectaria Xita
    Department of Endocrinology, University of Ioannina, Ioannina 45110, Greece
    J Clin Endocrinol Metab 91:1660-6. 2006
    ..Although PCOS manifests clinically during adolescence, emerging data suggest that the natural history of PCOS may originate in intrauterine life...
  46. ncbi request reprint Possible reasons for different pattern disappearance of thyroglobulin and thyroid peroxidase autoantibodies in patients with differentiated thyroid carcinoma following total thyroidectomy and iodine-131 ablation
    D Thomas
    Department of Endocrinology, Diabetes and Metabolism, Metaxa Memorial Anticancer Research Hospital, Piraeus, Greece
    J Endocrinol Invest 30:173-80. 2007
    ..Although tumor size and age may influence the pattern of thyroid autoantibody reduction, the exact reasons for the different rhythm of autoantibodies decrease must further be evaluated...
  47. ncbi request reprint Reduced serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 levels in adults with inflammatory bowel disease
    K H Katsanos
    Hepato Gastroenterology Unit, School of Medicine, University of Ioannina, Ioannina, 451 10, Greece
    Growth Horm IGF Res 11:364-7. 2001
    ..11 pg/ml, P<0.0001). The reduced IGF-1 and IGFBP-3 levels in patients with active IBD suggest that this systemic inflammatory condition is associated with a degree of acquired GH resistance, possibly induced by inflammatory cytokines...
  48. doi request reprint Detection of herpes virus DNA in post-operative thyroid tissue specimens of patients with autoimmune thyroid disease
    D Thomas
    Department of Endocrinology, Diabetes and Metabolism, Metaxa Memorial Anticancer Research Hospital, Piraeus, Greece
    Exp Clin Endocrinol Diabetes 116:35-9. 2008
    ....
  49. ncbi request reprint The role of fine-needle aspiration biopsy in the management of patients with thyroid nodules
    P Zagorianakou
    Department of Pathology Cytology, Medical School, University of Ioannina, Greece
    In Vivo 19:605-9. 2005
    ..We conclude that FNA is an effective screening test in the evaluation of the necessity for surgical treatment in patients with thyroid nodules...
  50. ncbi request reprint The Sp1 COLIA1 gene polymorphism, and not vitamin D receptor or estrogen receptor gene polymorphisms, determines bone mineral density in postmenopausal Greek women
    Z Efstathiadou
    Division of Endocrinology, Department of Internal Medicine, University of Ioannina School of Medicine, Ioannina, Greece
    Osteoporos Int 12:326-31. 2001
    ..When all five polymorphisms are considered simultaneously, the Sp1 COLIA1 polymorphism seems to have the most unequivocal effect on BMD, at least in postmenopausal women...
  51. ncbi request reprint Apolipoprotein E polymorphism is not associated with spinal bone mineral density in peri- and postmenopausal Greek women
    Z Efstathiadou
    Division of Endocrinology, Department of Internal Medicine, University of Ioannina School of Medicine, Ioannina, Greece
    Maturitas 48:259-64. 2004
    ..The aim of the present study was to determine the possible effect of ApoE gene polymorphism on spinal bone mineral density and metabolic bone markers in Greek women...
  52. ncbi request reprint Combined estrogen receptor alpha and estrogen receptor beta genotypes influence the age of menarche
    I Stavrou
    Department of Endocrinology and Laboratory of Reproductive Genetics, University of Ioannina, 45110 Ioannina, Greece
    Hum Reprod 21:554-7. 2006
    ..In the present study, we examined whether ERbeta genotypes alone, or in combination with ERalpha genotypes, may also influence onset of menarche...
  53. ncbi request reprint Isolated ACTH deficiency associated with Crohn's disease
    G Kalambokis
    Department of Internal Medicine, Medical School of Ioannina, Ioannina, Greece
    J Endocrinol Invest 27:961-4. 2004
    ..However more evidence is needed before isolated ACTH deficiency is added to the list of extraintestinal manifestations of CD...
  54. ncbi request reprint The role of Fas-mediated apoptosis in thyroid disease
    M Andrikoula
    Division of Endocrinology, Department of Medicine, University of Ioannina Medical School, Ioannina 45110, Greece
    Eur J Endocrinol 144:561-8. 2001
    ..However, the exact mechanisms involved in the regulation of apoptosis in thyroid disease remain unclear. Further investigation is needed...
  55. ncbi request reprint Association of SHBG gene polymorphism with menarche
    N Xita
    Department of Endocrinology and Laboratory of Reproductive Genetics, University of Ioannina, Ioannina, Greece
    Mol Hum Reprod 11:459-62. 2005
    ..24+/-1.15 years) than those with shorter allele genotypes (12.67+/-1.15, P=0.018). These findings provide evidence for a genetic contribution of SHBG gene to the age of menarche...
  56. ncbi request reprint Correlation of estrogen receptor beta gene polymorphisms with spinal bone mineral density in peri- and post-menopausal Greek women
    Z Efstathiadou
    Division of Endocrinology, Department of Internal Medicine, University of Ioannina School of Medicine, 45110 Ioannina, Greece
    Maturitas 53:380-5. 2006
    ..05]. Furthermore, no interaction between the two polymorphisms on BMD was found. In conclusion, in a Greek female post-menopausal population, the two ERbeta gene polymorphisms were not associated with BMD, or metabolic bone markers...
  57. ncbi request reprint Transcription factor-mediated proliferation and apoptosis in benign and malignant thyroid lesions
    Konstantinos P Letsas
    Second Department of Cardiology, Evangelismos General Hospital of Athens, Greece
    Pathol Int 55:694-702. 2005
    ..Furthermore, prothymosin alpha may promote cell survival through the Bcl2 anti-apoptotic pathway, while E2F-1-induced apoptosis via p53-independent pathways may be associated with transcriptional activation of bax pro-apoptotic gene...
  58. ncbi request reprint Fine-needle aspiration biopsy-RT-PCR expression analysis of prothymosin alpha and parathymosin in thyroid: novel proliferation markers?
    Konstantinos P Letsas
    Medical School of Ioannina, Greece
    Neoplasma 54:57-62. 2007
    ....