S Tsagarakis

Summary

Affiliation: University of Athens
Country: Greece

Publications

  1. ncbi request reprint A reappraisal of the utility of somatostatin receptor scintigraphy in patients with ectopic adrenocorticotropin Cushing's syndrome
    S Tsagarakis
    Department of Endocrinology, Diabetes, and Metabolism, Evangelismos Hospital, 10676 Athens, Greece
    J Clin Endocrinol Metab 88:4754-8. 2003
  2. ncbi request reprint The desmopressin and combined CRH-desmopressin tests in the differential diagnosis of ACTH-dependent Cushing's syndrome: constraints imposed by the expression of V2 vasopressin receptors in tumors with ectopic ACTH secretion
    S Tsagarakis
    Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece
    J Clin Endocrinol Metab 87:1646-53. 2002
  3. ncbi request reprint Lymphocytic hypophysitis: late recurrence following successful transsphenoidal surgery
    Stylianos Tsagarakis
    Department of Endocrinology, Diabetes and Metabolism Evangelismos Hospital, and 2nd Department of Radiology, University of Athens, Athens, Greece
    Endocrine 25:85-90. 2004
  4. ncbi request reprint The application of the combined corticotropin-releasing hormone plus desmopressin stimulation during petrosal sinus sampling is both sensitive and specific in differentiating patients with Cushing's disease from patients with the occult ectopic adrenocort
    S Tsagarakis
    Department of Endocrinology, Athens Polyclinic Hospital, Athens, Greece
    J Clin Endocrinol Metab 92:2080-6. 2007
  5. ncbi request reprint Diabetes insipidus, secondary hypoadrenalism and hypothyroidism after traumatic brain injury: clinical implications
    S Tsagarakis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    Pituitary 8:251-4. 2005
  6. ncbi request reprint Endogenous subclinical hypercortisolism: Diagnostic uncertainties and clinical implications
    S Tsagarakis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    J Endocrinol Invest 29:471-82. 2006
  7. ncbi request reprint Food-dependent androgen and cortisol secretion by a gastric inhibitory polypeptide-receptor expressive adrenocortical adenoma leading to hirsutism and subclinical Cushing's syndrome: in vivo and in vitro studies
    S Tsagarakis
    Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece
    J Clin Endocrinol Metab 86:583-9. 2001
  8. ncbi request reprint Pituitary-adrenal responses to human corticotropin-releasing hormone in critically ill patients
    Ioanna Dimopoulou
    Pesmazoglou 2 Street, 14561, Kifissia, Athens, Greece
    Intensive Care Med 33:454-9. 2007
  9. ncbi request reprint Endocrine alterations in critically ill patients with stroke during the early recovery period
    Ioanna Dimopoulou
    Department of Critical Care Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece
    Neurocrit Care 3:224-9. 2005
  10. ncbi request reprint A prospective study on adrenal cortex responses and outcome prediction in acute critical illness: results from a large cohort of 203 mixed ICU patients
    Ioanna Dimopoulou
    Attikon Hospital, Medical School, Second Department of Critical Care Medicine, University of Athens, 2 Pesmazoglou Street, 14561 Athens, Greece
    Intensive Care Med 33:2116-21. 2007

Collaborators

Detail Information

Publications34

  1. ncbi request reprint A reappraisal of the utility of somatostatin receptor scintigraphy in patients with ectopic adrenocorticotropin Cushing's syndrome
    S Tsagarakis
    Department of Endocrinology, Diabetes, and Metabolism, Evangelismos Hospital, 10676 Athens, Greece
    J Clin Endocrinol Metab 88:4754-8. 2003
    ..In summary, in this study a substantial number of patients had positive tumor localization by SRS. Therefore, SRS is a useful tool in the evaluation of patients with EAS...
  2. ncbi request reprint The desmopressin and combined CRH-desmopressin tests in the differential diagnosis of ACTH-dependent Cushing's syndrome: constraints imposed by the expression of V2 vasopressin receptors in tumors with ectopic ACTH secretion
    S Tsagarakis
    Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece
    J Clin Endocrinol Metab 87:1646-53. 2002
    ..Moreover, following the combined CRH-desmopressin test only the ACTH but not the F responses were diagnostically useful, but still far from completely discriminating patients with CD and EAS...
  3. ncbi request reprint Lymphocytic hypophysitis: late recurrence following successful transsphenoidal surgery
    Stylianos Tsagarakis
    Department of Endocrinology, Diabetes and Metabolism Evangelismos Hospital, and 2nd Department of Radiology, University of Athens, Athens, Greece
    Endocrine 25:85-90. 2004
    ....
  4. ncbi request reprint The application of the combined corticotropin-releasing hormone plus desmopressin stimulation during petrosal sinus sampling is both sensitive and specific in differentiating patients with Cushing's disease from patients with the occult ectopic adrenocort
    S Tsagarakis
    Department of Endocrinology, Athens Polyclinic Hospital, Athens, Greece
    J Clin Endocrinol Metab 92:2080-6. 2007
    ..A crucial issue, however, is whether such an amplified stimulation may affect the specificity of the procedure, and this was the main aim of the present study...
  5. ncbi request reprint Diabetes insipidus, secondary hypoadrenalism and hypothyroidism after traumatic brain injury: clinical implications
    S Tsagarakis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    Pituitary 8:251-4. 2005
    ..Therefore, assessment of the integrity of ADH secretion, hypothalamic-pituitary adrenal (HPA) axis and thyroid axis is crucial to ensure survival and optimal rehabilitation of TBI patients...
  6. ncbi request reprint Endogenous subclinical hypercortisolism: Diagnostic uncertainties and clinical implications
    S Tsagarakis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    J Endocrinol Invest 29:471-82. 2006
    ..In summary, SH does exist and is associated with a negative impact in patients' health; however, hormonal cut-off criteria for decision-making remain to be defined...
  7. ncbi request reprint Food-dependent androgen and cortisol secretion by a gastric inhibitory polypeptide-receptor expressive adrenocortical adenoma leading to hirsutism and subclinical Cushing's syndrome: in vivo and in vitro studies
    S Tsagarakis
    Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece
    J Clin Endocrinol Metab 86:583-9. 2001
    ..Thus, aberrant expression of the GIP receptor does not exclusively involve cells of a zona fasciculata phenotype, as previously reported, but may also occur in other types of differentiated adrenocortical cells...
  8. ncbi request reprint Pituitary-adrenal responses to human corticotropin-releasing hormone in critically ill patients
    Ioanna Dimopoulou
    Pesmazoglou 2 Street, 14561, Kifissia, Athens, Greece
    Intensive Care Med 33:454-9. 2007
    ..To investigate the pattern of pituitary-adrenal responses to human corticotropin-releasing hormone (hCRH) in critically ill patients and to examine the relation between responses and clinical outcome...
  9. ncbi request reprint Endocrine alterations in critically ill patients with stroke during the early recovery period
    Ioanna Dimopoulou
    Department of Critical Care Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece
    Neurocrit Care 3:224-9. 2005
    ..Endocrine abnormalities in critically ill patients with stroke during the early recovery period have not been well characterized...
  10. ncbi request reprint A prospective study on adrenal cortex responses and outcome prediction in acute critical illness: results from a large cohort of 203 mixed ICU patients
    Ioanna Dimopoulou
    Attikon Hospital, Medical School, Second Department of Critical Care Medicine, University of Athens, 2 Pesmazoglou Street, 14561 Athens, Greece
    Intensive Care Med 33:2116-21. 2007
    ..To assess whether adrenal cortex hormones predict ICU mortality in acute, mixed, critically ill patients...
  11. ncbi request reprint High incidence of neuroendocrine dysfunction in long-term survivors of aneurysmal subarachnoid hemorrhage
    Ioanna Dimopoulou
    Department of Critical Care Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece
    Stroke 35:2884-9. 2004
    ..To investigate the incidence, pattern, and magnitude of neuroendocrine changes in long-term survivors of aneurysmal subarachnoid hemorrhage (SAH)...
  12. ncbi request reprint Acromegaly caused by ectopic growth hormone-releasing hormone secretion by a carcinoid bronchial tumor: a rare entity
    Kalliopi Athanassiadi
    Department of Thoracic Surgery, Evangelismos General Hospital, Athens, Greece
    J Thorac Cardiovasc Surg 128:631-2. 2004
  13. ncbi request reprint The low-dose corticotropin stimulation test in acute traumatic and non-traumatic brain injury: incidence of hypo-responsiveness and relationship to outcome
    Ioanna Dimopoulou
    Department of Critical Care Medicine, Evangelismos Hospital, Medical School, National and Kapodistrian University of Athens, 10675 Athens, Greece
    Intensive Care Med 30:1216-9. 2004
    ..To investigate adrenal responses to the low-dose corticotropin (ACTH) stimulation test in acute traumatic or non-traumatic brain injury (BI) and to assess its value in predicting outcome...
  14. ncbi request reprint Relationship of thyroid function to post-traumatic S-100b serum levels in survivors of severe head injury: preliminary results
    Ioanna Dimopoulou
    Department of Critical Care Medicine, Evangelismos Hospital, Medical School, National and Kapodistrian University of Athens, 45 47 Ipsilandou Street, 106 75 Athens, Greece
    Intensive Care Med 30:298-301. 2004
    ..To assess thyroid function abnormalities in survivors of severe head trauma and to examine their relationship with indices of brain injury severity...
  15. ncbi request reprint Hypothalamic-pituitary-adrenal axis dysfunction in critically ill patients with traumatic brain injury: incidence, pathophysiology, and relationship to vasopressor dependence and peripheral interleukin-6 levels
    Ioanna Dimopoulou
    Department of Clinical Care Medicine, Evangelismos Hospital, Athens, Greece
    Crit Care Med 32:404-8. 2004
    ....
  16. ncbi request reprint High prevalence of decreased cortisol reserve in brain-dead potential organ donors
    Ioanna Dimopoulou
    Departments of Critical Care Medicine, Evangelismos Hospital, Athens, Greece
    Crit Care Med 31:1113-7. 2003
    ..To investigate the adrenocortical function in brain-dead patients, potential organ donors...
  17. ncbi request reprint Endocrine abnormalities in critical care patients with moderate-to-severe head trauma: incidence, pattern and predisposing factors
    Ioanna Dimopoulou
    Department of Critical Care Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece
    Intensive Care Med 30:1051-7. 2004
    ..To investigate the incidence and type of endocrine abnormalities in critical care patients with traumatic brain injury (TBI) and to examine their relationships to possible predisposing factors...
  18. ncbi request reprint Evaluation of GH reserve in patients with adrenal incidentalomas and biochemical evidence of subclinical autonomous glucocorticoid hypersecretion
    M Tzanela
    Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece
    Clin Endocrinol (Oxf) 62:597-602. 2005
    ..The aim of the present study was to evaluate whether SAGH in patients presented with adrenal incidentalomas has a negative effect on GH secretory reserve...
  19. ncbi request reprint Thyroid function changes and cytokine alterations following major surgery
    Ioannis Ilias
    Department of Endocrinology, Elena Venizelou Hospital, Athens, Greece
    Neuroimmunomodulation 14:243-7. 2007
    ..Significant negative correlations were noted among TNF-alpha, IL-6 and IL-8 against T(3) and FT(4). Cytokines are responsible, at least in part, for NTI following major operations...
  20. ncbi request reprint Pituitary-adrenal responses following major abdominal surgery
    Ioanna Dimopoulou
    2nd Department of Critical Care Medicine, Attikon Hospital, Athens University School of Medicine, Athens, Greece
    Hormones (Athens) 7:237-42. 2008
    ..Perioperative pituitary-adrenal responses after major abdominal surgery have not been well characterized. The aim of the present study was to further clarify perioperative pituitary-adrenal responses...
  21. ncbi request reprint Contribution of endocrine parameters in predicting outcome of multiple trauma patients in an intensive care unit
    Ioannis Ilias
    Department of Endocrinology, Elena Venizelou Hospital, and Athens University School of Medicine, Greece
    Hormones (Athens) 6:218-26. 2007
    ..To evaluate whether tentative prognostic models for intensive care unit survival of multiple trauma patients could be improved by including endocrine parameters...
  22. doi request reprint Clinical and biochemical impact of BCL1 polymorphic genotype of the glucocorticoid receptor gene in patients with adrenal incidentalomas
    M Tzanela
    Department of Endocrinology, Evangelismos Hospital, 45 47 Ipsilantous St, Athens, Greece
    J Endocrinol Invest 35:395-400. 2012
    ..The genotype- phenotype associations of this polymomorphism in patients presenting with AI has not been extensively investigated...
  23. ncbi request reprint Assessment of GH reserve before and after successful treatment of adult patients with Cushing's syndrome
    Marinella Tzanela
    Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, 10676 Athens, Greece
    Clin Endocrinol (Oxf) 60:309-14. 2004
    ..The aim of the present study was the evaluation of GH reserve in adult patients with CS before and after correction of cortisol excess...
  24. doi request reprint Role of [(18)F]FDG-PET/CT in the detection of occult recurrent medullary thyroid cancer
    Evangelia Skoura
    Department of Nuclear Medicine, Evangelismos Hospital, Athens, Greece
    Nucl Med Commun 31:567-75. 2010
    ..In this study we report our experience with 2-deoxy-2-[(18)F]fluoro-D-glucose positron emission tomography/computed tomography ([(18)F]FDG-PET/CT) in the evaluation of this specific group...
  25. doi request reprint Ex-vivo effect of dexamethasone on cytokine production from whole blood of septic patients: correlation with disease severity
    Evangelos J Giamarellos-Bourboulis
    4th Department of Internal Medicine, University of Athens, Medical School, Greece
    Cytokine 49:89-94. 2010
    ....
  26. ncbi request reprint Hypothalamic-pituitary dysfunction in critically ill patients with traumatic and nontraumatic brain injury
    Ioanna Dimopoulou
    Second Department of Critical Care Medicine, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, Greece
    Intensive Care Med 31:1020-8. 2005
    ..A significant number of studies have shown that critically ill patients with brain injury (BI) frequently exhibit abnormal pituitary hormonal responses during the immediate postinjury period...
  27. ncbi request reprint Bilateral inferior petrosal sinuses sampling in the routine investigation of Cushing's syndrome: a comparison with MRI
    Ioannis S Kaskarelis
    Department of Radiology, Evangelismos General Hospital, 11 Amasias St, Athens, Greece 11634
    AJR Am J Roentgenol 187:562-70. 2006
    ..We compare the diagnostic performance of BIPSS and MRI in detecting an ACTH-secreting source, and we suggest the diagnostic protocol that we found beneficial for the management of patients with CS...
  28. ncbi request reprint The impact of chronic in vivo glucocorticoid excess on the functional characteristics of human skin fibroblasts obtained from patients with endogenous Cushing's syndrome
    Irene Zervolea
    Laboratory of Cell Proliferation and Ageing, Institute of Biology, National Centre for Scientific Research Demokritos, 15310 Athens, Greece
    Eur J Endocrinol 152:895-902. 2005
    ..As there are concerns that GCs may generate permanent adverse functional changes, we have investigated whether chronic in vivo exposure to GC excess results in persisting defects in skin fibroblasts...
  29. doi request reprint Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine
    Paul E Marik
    Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Crit Care Med 36:1937-49. 2008
    ..To develop consensus statements for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients...
  30. ncbi request reprint Reproducibility of the corticotropin stimulation test in septic shock
    Ioanna Dimopoulou
    Anesth Analg 103:1056-7; author reply 1057. 2006
  31. ncbi request reprint A newly detected mutation of the RET protooncogene in exon 8 as a cause of multiple endocrine neoplasia type 2A
    Sotirios Bethanis
    Department of Endocrinology, Athens Polyclinic, Athens, Greece
    Hormones (Athens) 6:152-6. 2007
    ..Furthermore, patients with FMTC and exon 8 mutations should also be screened for pheochromocytoma...
  32. ncbi request reprint Immunohistochemical localization of interleukin-6 in peripheral human endocrine glands
    George Kontogeorgos
    Department of Pathology, G Genimatas Athens General Hospital, Greece
    Endocrine 17:135-40. 2002
    ..In conclusion, IL-6 immunoreactivity is present in almost all the human endocrine glands and it expressed in a cell-specific manner. These observations provide further support for the existence of local immune-endocrine interactions...
  33. ncbi request reprint Prior chronic in vivo glucocorticoid excess leads to an anabolic phenotype and an extension of cellular life span of skin fibroblasts in vitro
    Dimitris Kletsas
    Laboratory of Cell Proliferation and Ageing, Institute of Biology, National Centre for Scientific Research Demokritos, 15310 Athens, Greece
    Ann N Y Acad Sci 1100:449-54. 2007
    ....
  34. ncbi request reprint Chronic in vivo exposure to glucocorticoids prolongs cellular lifespan: the case of Cushing's syndrome-patients' fibroblasts
    Harris Pratsinis
    Laboratory of Cell Proliferation and Ageing, Institute of Biology, National Centre for Scientific Research, Demokritos, 153 10 Athens, Greece
    Exp Gerontol 37:1237-45. 2002
    ..These results support the hypothesis that stress response may have beneficial consequences in cellular longevity, as well as in tissue homeostasis...